Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institutionsort ascending Stage Project Objective Details
Other Embryonic Stem Cell,
iPS Cell
Cell processing & handling X-Therma
Proof of Concept, Tool/Resources/Bottleneck
Type 1 diabetes Embryonic Stem Cell Donor cell therapy ViaCyte
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy ViaCyte
Development Candidate
Bone or Cartilage Disease Embryonic Stem Cell Donor cell therapy USC
Pre-IND/IDE or Equivalent
Hearing Loss iPS Cell Model system development USC
Proof of Concept, Tool/Resources/Bottleneck
Age-related macular degeneration Embryonic Stem Cell Biologic USC
Pre-IND/IDE or Equivalent
Liver Disease Directly Reprogrammed Cell Gene modification UCSF
Development Candidate
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
IND
Type 1 diabetes Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Parkinson's Disease Adult Stem Cell Gene-modified, donor cell therapy UCSF
IND
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Type 1 diabetes Embryonic Stem Cell Donor cell therapy UCSF
Development Candidate
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Development Candidate, Proof of Concept
Alpha Thalassemia Major Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Respiratory Disorders Directly Reprogrammed Cell Model system development UCSF
Research Insights
Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Cancer Stem Cell Antibody UCSD
Clinical Trial, Phase 1 or Phase 1/2
Vision Loss iPS Cell Small molecule therapy UCSD
Development Candidate, Proof of Concept
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy UCSD
Development Candidate, Proof of Concept
Cystinosis,
Kidney Failure
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis,
Spinal Cord Injury
Embryonic Stem Cell,
iPS Cell
Cell imaging & tracking UCSD
Research Insights
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody UCSD
Development Candidate, Proof of Concept
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Vascular Disease Adult Stem Cell Biologic UCSD
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Small molecule therapy UCSD
Pre-IND/IDE or Equivalent
Leukemia, Acute Myeloid (AML) Embryonic Stem Cell Donor cell therapy UCSD
Pre-IND/IDE or Equivalent
Heart Disease,
Danon Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Development Candidate, Proof of Concept
Cancer Cancer Stem Cell Gene-modified, personalized cell therapy UCSD
Pre-IND/IDE or Equivalent
Age-related macular degeneration iPS Cell Exploring disease mechanisms UCSD
Research Insights
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Hyper IgM Syndrome,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Lung Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Sarcoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Hyper IgM Syndrome Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Muscular Dystrophy Embryonic Stem Cell,
iPS Cell
Personalized cell therapy UCLA
Development Candidate
Stroke iPS Cell Donor cell therapy UCLA
Development Candidate
Corneal Damage Adult Stem Cell Personalized cell therapy UCLA
IND
Neurological Disorders,
Zika virus
Adult Stem Cell,
iPS Cell
Vaccine UCLA
Development Candidate
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Age-related macular degeneration iPS Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders,
Leukemia
Adult Stem Cell Exploring stem cell mechanisms UCLA
Development Candidate, Proof of Concept, Research Insights
Cancer Adult Stem Cell Gene-modified, donor cell therapy UCLA
Development Candidate, Proof of Concept
Corneal Damage Adult Stem Cell Personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Bone or Cartilage Disease Adult Stem Cell Donor cell therapy UCLA
Proof of Concept
Retinitis Pigmentosa Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Pre-IND/IDE or Equivalent
Traumatic Brain Injury Embryonic Stem Cell Donor cell therapy UC Irvine
Development Candidate

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