Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institutionsort descending Stage Project Objective Details
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer Adult Stem Cell Donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Intervertebral disc degeneration Adult Stem Cell Personalized cell therapy Ankasa
IND
Parkinson's Disease Gene Therapy, cell free Brain Neurotherapy Bio
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Type 1 diabetes Adult Stem Cell Personalized cell therapy Caladrius Biosciences
Clinical Trial, Phase 2
Arthritis,
Osteoarthritis
Adult Stem Cell Small molecule therapy Calibr
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Pulmonary Hypertension,
Vascular Disease
Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Cellerant Therapeutics
IND
COVID-19,
Respiratory Disorders
Adult Stem Cell Donor cell therapy Celularity Inc
Clinical Trial, Phase 1 or Phase 1/2
Liver Disease iPS Cell Gene-modified, donor cell therapy CHLA
Development Candidate, Proof of Concept
Intestinal Disease,
Neurological Disorders
iPS Cell Donor cell therapy CHLA
Pre-IND/IDE or Equivalent
Blood Cancer,
Bone Marrow Transplant and Viral Infection
Adult Stem Cell Donor cell therapy CHLA
Clinical Trial, Phase 1 or Phase 1/2
Beta Thalassemia,
Sickle Cell Disease
Adult Stem Cell Diagnostic Test CHORI
Regulated Lab Test, Ready for Validation
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy CHORI
Pre-IND/IDE or Equivalent
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
Brain Cancer,
Breast Cancer
Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
B cell cancers,
Leukemia
Cancer Stem Cell Antibody COH
Development Candidate, Proof of Concept
HIV/AIDS Personalized cell therapy COH
IND
COVID-19,
Respiratory Disorders
Convalescent Plasma COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Canavan Disease iPS Cell Gene-modified, personalized cell therapy COH
Pre-IND/IDE or Equivalent
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
IND
Ovarian Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Development Candidate, Proof of Concept
COVID-19 Adult Stem Cell Gene-modified, donor cell therapy COH
Development Candidate, Proof of Concept
Sickle Cell Disease Adult Stem Cell Donor cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Ovarian Cancer Adult Stem Cell Gene-modified, donor cell therapy COH
Pre-IND/IDE or Equivalent
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Solid Tumors iPS Cell Gene-modified, donor cell therapy Fate Therapeutics
IND
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Colon Cancer Cancer Stem Cell Antibody Forty Seven
Clinical Trial, Phase 1 or Phase 1/2
Heart Disease,
Neurological Disorders
Embryonic Stem Cell,
iPS Cell
Tissue engineering Gladstone
Proof of Concept, Research Insights
Dementia iPS Cell Donor cell therapy Gladstone
Development Candidate, Proof of Concept
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Retinitis Pigmentosa Donor cell therapy jCyte
Clinical Trial, Phase 2
Retinitis Pigmentosa Other Donor cell therapy jCyte
Clinical Trial, Phase 2
Spinal Cord Injury Embryonic Stem Cell Donor cell therapy Lineage Cell
Clinical Trial, Phase 1 or Phase 1/2
Bone or Cartilage Disease Adult Stem Cell Small molecule therapy MAX BioPharma
Pre-IND/IDE or Equivalent
Kidney Failure Adult Stem Cell Donor cell therapy Medeor Therapeutics
Clinical Trial, Phase 3
Epilepsy Embryonic Stem Cell Donor cell therapy Neurona Therapeutics
Pre-IND/IDE or Equivalent
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Vascular Disease iPS Cell Personalized cell therapy PAVIR
Proof of Concept, Research Insights
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Leukocyte Adhesion Deficiency Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy Salk
Development Candidate, Proof of Concept
Stroke Adult Stem Cell Gene-modified, donor cell therapy SanBio, Inc.
Clinical Trial, Phase 2
Brain Injury, hypoxic, ischemic Adult Stem Cell Donor cell therapy Sanford-Burnham
Pre-IND/IDE or Equivalent

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