Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Typesort descending Therapeutic or Technology Institution Stage Project Objective Details
IPEX Syndrome,
Immune Disease
Gene Therapy, cell free Stanford
IND
Retinitis Pigmentosa Donor cell therapy jCyte
Clinical Trial, Phase 2
Parkinson's Disease Gene Therapy, cell free Brain Neurotherapy Bio
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Personalized cell therapy COH
IND
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Development Candidate, Proof of Concept
Age-related macular degeneration Adult Stem Cell Donor cell therapy Stanford
Pre-IND/IDE or Equivalent
Vascular Disease Adult Stem Cell Biologic UCSD
Pre-IND/IDE or Equivalent
Brain Injury, hypoxic, ischemic Adult Stem Cell Donor cell therapy Sanford-Burnham
Pre-IND/IDE or Equivalent
Ovarian Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Development Candidate, Proof of Concept
Spina Bifida Adult Stem Cell Donor cell therapy UC Davis
IND
Type 1 diabetes Adult Stem Cell Personalized cell therapy Caladrius Biosciences
Clinical Trial, Phase 2
Stroke Adult Stem Cell Gene-modified, donor cell therapy SanBio, Inc.
Clinical Trial, Phase 2
Spinal Cord Injury Adult Stem Cell Donor cell therapy UC Irvine
Development Candidate
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer Adult Stem Cell Donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Alpha Thalassemia Major Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure Adult Stem Cell Donor cell therapy Medeor Therapeutics
Clinical Trial, Phase 3
Heart Disease,
Danon Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Development Candidate, Proof of Concept
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Cancer Adult Stem Cell Gene-modified, donor cell therapy UCLA
Development Candidate, Proof of Concept
Blood Disorders,
Leukemia
Adult Stem Cell Exploring stem cell mechanisms UCLA
Development Candidate, Proof of Concept, Research Insights
Kidney Failure Adult Stem Cell Donor cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Skeletal/Smooth Muscle disorders Adult Stem Cell Protein/peptide therapy Stanford
Research Insights
Corneal Damage Adult Stem Cell Personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Sickle Cell Disease Adult Stem Cell Donor cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Severe Combined Immunodeficiency, X-linked (X-SCID) Adult Stem Cell Antibody Stanford
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Bone or Cartilage Disease Adult Stem Cell Donor cell therapy UCLA
Proof of Concept
Severe Combined Immunodeficiency, Artemis deficient (ART-SCID) Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Intervertebral disc degeneration Adult Stem Cell Personalized cell therapy Ankasa
IND
Hyper IgM Syndrome,
Immune Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
B cell cancers,
Leukemia
Adult Stem Cell Gene-modified, personalized cell therapy Stanford
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
IND
Ovarian Cancer Adult Stem Cell Gene-modified, donor cell therapy COH
Pre-IND/IDE or Equivalent
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Stanford
IND
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Sarcoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Multiple Myeloma Adult Stem Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Antibody Stanford
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy CHORI
Pre-IND/IDE or Equivalent
Leukocyte Adhesion Deficiency Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3

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