Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Typesort descending Therapeutic or Technology Institution Stage Project Objective Details
HIV/AIDS Personalized cell therapy COH
IND
COVID-19,
Respiratory Disorders
Convalescent Plasma COH
Clinical Trial, Phase 1 or Phase 1/2
IPEX Syndrome,
Immune Disease
Gene Therapy, cell free Stanford
IND
Retinitis Pigmentosa Donor cell therapy jCyte
Clinical Trial, Phase 2
Parkinson's Disease Gene Therapy, cell free Brain Neurotherapy Bio
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
IND
Vascular Disease Adult Stem Cell Biologic UCSD
Pre-IND/IDE or Equivalent
Ovarian Cancer Adult Stem Cell Gene-modified, donor cell therapy COH
Pre-IND/IDE or Equivalent
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Sarcoma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Adult Stem Cell Personalized cell therapy Caladrius Biosciences
Clinical Trial, Phase 2
Multiple Myeloma Adult Stem Cell Personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Leukocyte Adhesion Deficiency Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Lung Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
HIV-related Lymphoma,
HIV/AIDS
Adult Stem Cell Gene-modified, personalized cell therapy UC Davis
Clinical Trial, Phase 1 or Phase 1/2
Type 1 diabetes Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Stanford
IND
Bone or Cartilage Disease Adult Stem Cell Small molecule therapy MAX BioPharma
Pre-IND/IDE or Equivalent
Immune Disease,
X-linked Chronic Granulomatous Disease
Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Clinical Trial, Phase 1 or Phase 1/2
Cystinosis,
Kidney Failure
Adult Stem Cell Gene-modified, personalized cell therapy UCSD
Clinical Trial, Phase 1 or Phase 1/2
Skeletal/Smooth Muscle disorders Adult Stem Cell Protein/peptide therapy Stanford
Research Insights
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Pre-IND/IDE or Equivalent
Skeletal/Smooth Muscle disorders Adult Stem Cell Small molecule therapy Stanford
Development Candidate
Blood Disorders,
Leukemia
Adult Stem Cell Exploring stem cell mechanisms UCLA
Development Candidate, Proof of Concept, Research Insights
Brain Cancer,
Breast Cancer
Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Hearing Loss Adult Stem Cell Protein/peptide therapy Stanford
Development Candidate, Proof of Concept
COVID-19,
Respiratory Disorders
Adult Stem Cell Model system development UCLA
Development Candidate, Proof of Concept, Tool/Resources/Bottleneck
Beta Thalassemia,
Sickle Cell Disease
Adult Stem Cell Diagnostic Test CHORI
Regulated Lab Test, Ready for Validation
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Parkinson's Disease Adult Stem Cell Gene-modified, donor cell therapy UCSF
IND
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Pre-IND/IDE or Equivalent
Arthritis,
Osteoarthritis
Adult Stem Cell Small molecule therapy Calibr
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
IND
Age-related macular degeneration Adult Stem Cell Donor cell therapy Stanford
Pre-IND/IDE or Equivalent
Kidney Failure Adult Stem Cell Biologic Humacyte
Clinical Trial, Phase 3
Brain Injury, hypoxic, ischemic Adult Stem Cell Donor cell therapy Sanford-Burnham
Pre-IND/IDE or Equivalent
Blood Cancer,
Bone Marrow Transplant and Viral Infection
Adult Stem Cell Donor cell therapy CHLA
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy UCLA
Development Candidate, Proof of Concept
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy UCSF
Development Candidate, Proof of Concept
Spina Bifida Adult Stem Cell Donor cell therapy UC Davis
IND
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy CHORI
Pre-IND/IDE or Equivalent
COVID-19 Adult Stem Cell Donor cell therapy UCSF
Clinical Trial, Phase 2

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