Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

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Disease Cell Type Therapeutic or Technology Institutionsort descending Stage Project Objective Details
Blood Cancer Adult Stem Cell Donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer Adult Stem Cell Gene-modified, donor cell therapy Angiocrine
Clinical Trial, Phase 1 or Phase 1/2
Parkinson's Disease iPS Cell Cell processing & handling Aspen Neuroscience Research Insights, Tool/Resources/Bottleneck
Sickle Cell Disease Adult Stem Cell Gene-modified, personalized cell therapy Boston Children's Hospital
Clinical Trial, Phase 2
Parkinson's Disease Vital Research Opportunity Gene Therapy, cell free Brain Neurotherapy Bio
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Personalized cell therapy BrainStorm
Clinical Trial, Phase 3
Retinitis Pigmentosa Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Pulmonary Hypertension,
Vascular Disease
Adult Stem Cell Donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
Amyotrophic Lateral Sclerosis Adult Stem Cell Gene-modified, donor cell therapy Cedars-Sinai
Clinical Trial, Phase 1 or Phase 1/2
COVID-19,
Respiratory Disorders
Adult Stem Cell Donor cell therapy Celularity Inc
Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer,
Bone Marrow Transplant and Viral Infection
Adult Stem Cell Donor cell therapy CHLA
Clinical Trial, Phase 1 or Phase 1/2
Intestinal Disease,
Neurological Disorders
iPS Cell Donor cell therapy CHLA
Pre-IND/IDE or Equivalent
Liver Disease iPS Cell Gene-modified, donor cell therapy CHLA
Development Candidate, Proof of Concept
HIV/AIDS Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
IND
Canavan Disease iPS Cell Gene-modified, personalized cell therapy COH
Pre-IND/IDE or Equivalent
Brain Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Ovarian Cancer Adult Stem Cell Gene-modified, personalized cell therapy COH
Development Candidate, Proof of Concept
COVID-19 Adult Stem Cell Gene-modified, donor cell therapy COH
Development Candidate, Proof of Concept
Ovarian Cancer Adult Stem Cell Gene-modified, donor cell therapy COH
Pre-IND/IDE or Equivalent
Hemophilia A Adult Stem Cell Gene modification COH
Development Candidate, Proof of Concept
Sickle Cell Disease Adult Stem Cell Donor cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer,
Breast Cancer
Adult Stem Cell Gene-modified, personalized cell therapy COH
Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS Personalized cell therapy COH
IND
COVID-19,
Respiratory Disorders
Vital Research Opportunity Convalescent Plasma COH
Clinical Trial, Phase 1 or Phase 1/2
COVID-19 Embryonic Stem Cell,
iPS Cell
Gene-modified, donor cell therapy COH
Proof of Concept
Sickle Cell Disease Adult Stem Cell Donor cell therapy ExCellThera Inc.
Clinical Trial, Phase 1 or Phase 1/2
Dementia iPS Cell Donor cell therapy Gladstone
Development Candidate, Proof of Concept
Leukemia, Acute Myeloid (AML) Cancer Stem Cell Antibody Immune-Onc Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Severe Combined Immunodeficiency, X-linked (X-SCID) Adult Stem Cell Antibody Jasper Therapeutics, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa Therapeutic Approach jCyte
Clinical Trial, Phase 2
Retinitis Pigmentosa Other Donor cell therapy jCyte
Clinical Trial, Phase 2
Type 1 diabetes Embryonic Stem Cell Gene-modified, donor cell therapy Lundquist Institute
Development Candidate, Proof of Concept
Kidney Failure Adult Stem Cell Donor cell therapy Medeor Therapeutics
Clinical Trial, Phase 3
Epilepsy Embryonic Stem Cell Donor cell therapy Neurona Therapeutics
Pre-IND/IDE or Equivalent
Epilepsy Embryonic Stem Cell Donor cell therapy Neurona Therapeutics
Research Insights
Immune Disease,
Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy Orchard Therapeutics
Clinical Trial, Phase 2
Multiple Myeloma Adult Stem Cell Gene-modified, personalized cell therapy Poseida Therapeutics
Clinical Trial, Phase 1 or Phase 1/2
Bone or Cartilage Disease Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
Immune Disease,
Leukocyte Adhesion Deficiency
Adult Stem Cell Gene-modified, personalized cell therapy Rocket Pharmaceuticals, Inc.
Clinical Trial, Phase 1 or Phase 1/2
COVID-19,
Respiratory Disorders
iPS Cell Small molecule therapy Sanford-Burnham
Development Candidate, Proof of Concept
Brain Injury, hypoxic, ischemic Adult Stem Cell Donor cell therapy Sanford-Burnham
Pre-IND/IDE or Equivalent
Beta Thalassemia Adult Stem Cell Gene-modified, personalized cell therapy Sangamo
Clinical Trial, Phase 1 or Phase 1/2
Autism iPS Cell Small molecule therapy Scripps
Development Candidate, Proof of Concept
COVID-19 iPS Cell Small molecule therapy Scripps
Development Candidate, Proof of Concept
Immune Disease,
Severe Combined Immunodeficiency, X-linked (X-SCID)
Adult Stem Cell Gene-modified, personalized cell therapy St. Jude
Clinical Trial, Phase 1 or Phase 1/2
Bladder or Urinary Tract Disorder,
Incontinence
iPS Cell Personalized cell therapy Stanford
Pre-IND/IDE or Equivalent
IPEX Syndrome,
Immune Disease
Vital Research Opportunity Gene Therapy, cell free Stanford
IND
Age-related macular degeneration Adult Stem Cell Donor cell therapy Stanford
Pre-IND/IDE or Equivalent

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