All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Berkeley David Schaffer Tools and Technologies III Engineered Biomaterials for Scalable Manufacturing and High Viability Implantation of hPSC-Derived Cells to Treat Neurodegenerative Disease $1,239,276
Stanford University Irving Weissman Disease Team Therapy Development III Clinical Investigation of a Humanized Anti-CD47 Antibody in Targeting Cancer Stem Cells in Hematologic Malignancies and Solid Tumors $7,672,364
Gladstone Institutes Todd McDevitt Research Leadership Engineering microscale tissue constructs from human pluripotent stem cells $6,368,285
University of California, San Diego Shyni Varghese Tools and Technologies III Technologies to improve in vivo function of transplanted stem cells $1,393,200
University of California, Los Angeles Leif Havton Tools and Technologies III Development of a Relevant Pre-Clinical Animal Model as a Tool to Evaluate Human Stem Cell-Derived Replacement Therapies for Motor Neuron Injuries and Degenerative Diseases $1,308,711
University of California, Berkeley Lin He New Faculty II The roles of non-coding RNAs in the self-renewal and differentiation of pluripotent stem cells $1,406,823
Stanford University Fan Yang Tools and Technologies III Injectable Macroporous Matrices to Enhance Stem Cell Engraftment and Survival $1,452,708
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Development - Research Progenitor Cells Secreting GDNF for the Treatment of ALS $16,961,287
San Jose State University Tzvia Abramson Bridges Stem Cell Internships for Laboratory-based Learning (SCILL) $4,201,707
California State University, Channel Islands Ching-Hua Wang Bridges Curriculum Development and Implementation of Stem Cell Technology and Laboratory Management Emphasis in an Established MS Biotechnology and Bioinformatics Program at (REDACTED) and Co-development of a GE Course on Stem Cel $4,237,241
California State University, Long Beach Lisa Klig Bridges CIRM Stem Cell Research Biotechnology Training Program $3,513,898
Stanford University Robert Negrin Transplantation Immunology Regulatory T cell induced tolerance to ESC transplantation $1,382,658
Stanford University Garry Nolan Basic Biology II Kinase signaling analysis of iPS cell reprogramming and differentiation $1,343,100
University of California, Los Angeles Leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $75,628
City of Hope Larry Couture Tools and Technologies III Development of a scalable, practical, and transferable GMP-compliant suspension culture-based differentiation process for cardiomyocyte production from human embryonic stem cells. $899,728
University of Southern California Toshio Miki Tools and Technologies III Development of a clinical-grade extracorporeal liver support system using human induced pluripotent stem cell-derived hepatic cells $1,257,372
Salk Institute for Biological Studies Juan Carlos Izpisua Belmonte Early Translational III Direct reprogramming towards vascular progenitors for the treatment of ischemia $2,340,000
University of California, San Diego Shaochen Chen Tools and Technologies III Development of 3D Bioprinting Techniques using Human Embryonic Stem Cells Derived Cardiomyocytes for Cardiac Tissue Engineering $1,368,517
University of California, Los Angeles Carla Koehler Tools and Technologies III A small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs $1,283,900
Stanford University Vittorio Sebastiano Shared Labs Center for Human Embryonic Stem Cell Research and Education $3,434,600
Stanford University Irving Weissman Disease Team Research I Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells $18,759,276
University of California, San Francisco Daniel Lim Tools and Technologies II Development and preclinical testing of new devices for cell transplantation to the brain. $1,797,426
ViaCyte, Inc. Howard Foyt Strategic Partnership I Preclinical and clinical testing of a stem cell-based combination product for insulin-dependent diabetes $10,075,070
Stanford University Helen Blau Basic Biology V Mass Cytometry to Delineate the Human Muscle Stem Cell Hierarchy and Dysfunction in Aging $1,175,357
University of California, San Diego Thomas Kipps Disease Team Therapy Development III Therapeutic Eradication of Cancer Stem Cells $4,179,598
University of Southern California Mark Humayun Disease Team Therapy Development III Phase 1 Safety Assessment of CPCB-RPE1, hESC-derived RPE Cell Coated Parylene Membrane Implants, in Patients with Advanced Dry Age Related Macular Degeneration $17,128,661
San Francisco State University Carmen Domingo Bridges Bridges to Stem Cell Research $4,201,420
City of Hope Yanhong Shi Early Translational II Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
Cedars-Sinai Medical Center Paul Noble Basic Biology V Innate Immune Regulation of Lung Alveolar Stem Cell Renewal in Mouse and Man $624,816
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $1,721,129
University of California, Los Angeles Samantha Butler Basic Biology V Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $545,962
University of California, San Francisco Andrew Leavitt Tools and Technologies III Small molecule tools and scale-up technologies to expand human umbilical cord blood stem and progenitor cells for clinical and research use $1,416,600
Sanford-Burnham Medical Research Institute Stuart Lipton Early Translational IV Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke $885,000
University of California, San Diego Douglas Galasko Tissue Collection for Disease Modeling Collection of skin biopsies to prepare fibroblasts from patients with Alzheimer's disease and cognitively healthy elderly controls $643,693
University of California, Los Angeles Yi Sun Basic Biology III Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
University of California, San Diego Mana Parast New Faculty Physician Scientist Human pluripotent stem cell-based therapeutics for preeclampsia $2,974,750
Stanford University Joseph Wu Early Translational III Heart Repair with Human Tissue Engineered Myocardium $4,397,241
Stanford University Judith Shizuru Disease Team Therapy Development - Research A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $19,068,382
Sangamo BioSciences, Inc. Fyodor Urnov Strategic Partnership II A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells $6,374,150
University of California, San Diego Wei Wang Basic Biology V Systems-level discovery of the regulatory mechanisms directing differentiation of hESC $1,161,000
University of California, Merced Kara McCloskey Basic Biology V Directed Differentiation of Specialized Endothelial Cells $476,052
ViaCyte, Inc. Allan Robins Disease Team Research I Cell Therapy for Diabetes $22,999,933
StemCells, Inc. Alexandra Capela Disease Team Therapy Development - Research Restoration of memory in Alzheimer’s disease: a new paradigm using neural stem cell therapy $8,901,641
University of California, San Francisco Morton Cowan Early Translational III Gene Correction of Autologous Hematopoietic Stem Cells in Artemis Deficient SCID $3,931,662
University of California, Berkeley David Schaffer Shared Labs Human Embryonic Stem Cell Shared Research Laboratory $1,688,129
University of Southern California Robert Maxson Research Training II CIRM Stem Cell Biology Training Program $6,162,045
Buck Institute for Age Research Xianmin Zeng Shared Labs CIRM Shared Research Laboratory for Stem Cells and Aging $3,478,933
San Diego State University Ricardo Zayas New Faculty II The molecular basis underlying adult neurogenesis during regeneration and tissue renewal $1,712,225
Salk Institute for Biological Studies Senyon Choe SEED Grant A method to maintain and propagate pluripotent human ES cells $760,042
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
Cedars-Sinai Medical Center Eduardo Marbán Disease Team Research I Autologous cardiac-derived cells for advanced ischemic cardiomyopathy $5,560,232
Samumed, LLC John Hood Disease Team Therapy Planning I Clinical Development of an osteoinductive therapy to prevent osteoporosis-related fractures $99,110
University of Southern California Mohammad Pashmforoush New Faculty I Transcriptional Regulation of Cardiac Pacemaker Cell Progenitors $27,949
University of California, Los Angeles Martin Martin Tools and Technologies II Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
University of California, Berkeley Andrew Dillin Basic Biology V A Requirement for Protein Homeostasis in the Mediation of Stem Cell Health $1,034,100
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $1,638,357
Ludwig Institute for Cancer Research Bing Ren New Faculty II Mechanisms of chromatin dynamics at enhancers during ES cell differentiation $1,726,564
Salk Institute for Biological Studies Fred Gage New Cell Lines Development of Induced Pluripotent Stem Cells for Modeling Human Disease $1,737,720
University of California, Irvine Peter Bryant Training Grant I-1 Stem Cell Research Training Grant $1,935,487
Buck Institute for Age Research Mary McEachron Major Facilities CIRM Center of Excellence at Buck Institute for Age Research $20,500,000
University of California, San Diego Steve Dowdy Tools and Technologies I TAT Cell-Permeable Protein Delivery of siRNAs for Epigenetic Programming of Human Pluripotent and Adult Stem Cells $720,000
University of California, San Diego Mana Parast New Faculty II Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal $3,077,918
University of California, Riverside Michael Pirrung SEED Grant Stem Cell Survival and Differentiation Through Chemical Genetics $522,933
University of California, San Diego Eric Adler Early Translational III Identification of Novel Therapeutics for Danon Disease Using an iPS Model of the Disease $1,701,575
University of California, San Diego Eugene Yeo Basic Biology I RNA Binding Protein-mediated Post-transcriptional Networks Regulating HPSC Pluripotency $1,308,901
University of California, Los Angeles Shuo Lin Basic Biology III Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,382,400
Salk Institute for Biological Studies Samuel Pfaff Disease Team Planning Motor neuron diseases: Finding cures through basic, translational, and clinical collaboration $54,016
Palo Alto Institute for Research and Education Husein Hadeiba Transplantation Immunology Application of Tolerogenic Dendritic Cells for Hematopoietic Stem Cell Transplantation $733,061
Stanford University Joachim Hallmayer Tissue Collection for Disease Modeling Induced pluripotent stem cells from children with autism spectrum disorders $530,265
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,467,200
University of California, Los Angeles Noriyuki Kasahara SEED Grant Down-Regulation of Alloreactive Immune Responses to hES Cell-Derived Graft Tissues $399,239
University of California, Davis John Laird Disease Team Therapy Development - Research Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia $12,113,602
Salk Institute for Biological Studies Ronald Evans Basic Biology II Molecular Characterization and Functional Exploration of Nuclear Receptors in hiPSCs $1,712,880
University of California, Los Angeles Stanley Carmichael Disease Team Planning Development of a Stem Cell Therapy to Promote Functional Recovery in Stroke $42,748
Stanford University Howard Chang New Faculty I Noncoding RNAs in Cell Fate Determination $2,985,894
Sanford-Burnham Medical Research Institute Mark Mercola Comprehensive Grant Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes $2,832,000
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
iPierian, Inc. John Dimos Early Translational II New Drug Discovery for SMA using Patient-derived Induced Pluripotent Stem Cells $2,410,000
City College Of San Francisco Carin Zimmerman Bridges Stem Cell Training Enhancement Program $2,732,437
University of California, Irvine Peter Donovan Shared Labs Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $2,107,376
University of California, San Diego David Traver New Faculty I Genetic dissection of mesodermal commitment to the hematopoietic fates. $2,150,620
BioTime, Inc. Michael West Early Translational I Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines $4,721,706
University of Southern California Martin Pera New Cell Lines New Technology ForThe Derivation of Human Pluripotent Stem Cell Lines For Clinical Use $1,266,134
Sanford-Burnham Medical Research Institute Gregg Duester SEED Grant Retinoic Acid-FGF Antagonism during Motor Neuron Differentiation of Human ES Cells $695,229
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
City of Hope John Zaia Disease Team Research I ZIinc Finger Nuclease-Based Stem Cell Therapy for AIDS $14,536,969
Sanford-Burnham Medical Research Institute Stuart Lipton Disease Team Therapy Planning I hESC-derived NPCs Programmed with MEF2C for Cell Transplantation in Parkinson’s Disease $96,448
Stanford University Brian Rutt Tools and Technologies II Development of Single Cell MRI Technology using Genetically-Encoded Iron-Based Reporters $1,833,348
University of California, San Diego Miles Wilkinson Basic Biology V New Regulators of Spermatogonial Stem Cells: RHOX Homeobox Transcription Factors $560,160
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $1,737,694
University of California, San Diego Shyni Varghese New Faculty II A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
University of California, San Francisco Long-cheng Li New Cell Lines Induction of pluripotent stem cells by small RNA-guided transcriptional activation $1,368,461
Scripps Research Institute Peter Schultz Training Grant I-2 Training Grant I $1,021,395
Sanford Consortium for Regenerative Medicine Edward Holmes Major Facilities Sanford Consortium for Regenerative Medicine $42,827,439
University of California, Irvine Lisa Flanagan Tools and Technologies I Novel Separation of Stem Cell Subpopulations $861,122
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,075,251
Sanford-Burnham Medical Research Institute Huei-sheng Chen SEED Grant Development of Neuro-Coupled Human Embryonic Stem Cell-Derived Cardiac Pacemaker Cells. $695,680
University of Southern California Toshio Miki Early Translational III Generation of hepatic cell from placental stem cell for congenital metabolic disorders $1,750,375
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,705,500
Gladstone Institutes Deepak Srivastava Disease Team Planning Pluripotent Stem Cell–Based Therapy for Heart Disease $13,505

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