All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
Humacyte, Inc. Jeffrey Lawson Clinical Trial Stage Projects A Phase 3 Study Comparing the Utility of Human Acellular Vessels to Arteriovenous Fistula in Subjects with End-Stage Renal Disease (California Sites) $14,082,865
Forty Seven Inc. Mark Chao Clinical Trial Stage Projects A Phase 1b Trial of Hu5F9-G4 Monotherapy or Hu5F9-G4 in Combination with Azacitidine in Patients with Acute Myeloid Leukemia $5,000,000
City of Hope, Beckman Research Institute Christine Brown Clinical Trial Stage Projects Phase I Study of Chimeric Antigen Receptor Engineered Central Memory T cells for the Treatment of Malignant Glioma $12,753,854
University of California, Davis Mehrdad Abedi Alpha Stem Cell Clinics Network Expansion Alpha Stem Cell Clinic for Northern and Central California $7,905,671
Children's Hospital of Oakland Research Institute Mark Walters Alpha Stem Cell Clinics Network Expansion University of California, San Francisco (UCSF) CIRM Alpha Stem Cell Clinic $7,999,999
Angiocrine Bioscience, Inc. Paul Finnegan Clinical Trial Stage Projects AB-110-001 Phase 1b Trial and Related Activities to Support Clinical Development of AB-110 $5,000,000
University of California, San Diego Thomas Kipps Clinical Trial Stage Projects A Phase 1b/2a Study of the ROR1-Targeting Monoclonal Antibody, Cirmtuzumab, and the Bruton Tyrosine Kinase Inhibitor, Ibrutinib, in B-Cell Cancers $18,292,674
International Alliance for Biological Standardization Anthony Lubiniecki Conference - Manage a Symposium on Pluripotent Stem Cell Manufacturing Basis of Standardization for Cell Therapies $100,000
BrainStorm Cell Therapeutics Ralph Kern Clinical Trial Stage Projects A Phase 3, Randomized, Placebo-controlled Multicenter Study to Evaluate Efficacy & Safety of Repeated Administrations of NurOwn® in Patients with ALS $15,912,390
University of California, San Diego Ezra Cohen Therapeutic Translational Research Projects Development of ROR1 CAR-T cells to target cancer stem cells in advanced malignancies $5,795,584
JDRF International Esther Latres Conference II JDRF Encapsulation Consortium Fall 2017 Meeting $42,425
University of California, Los Angeles Caroline Kuo Quest - Discovery Stage Research Projects Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome $1,512,333
X-Therma Inc. Xiaoxi Wei Quest - Discovery Stage Research Projects Non-Toxic, Highly-Effective Bioinspired Cryoprotectants for On-Demand Stem Cell Therapies $887,883
University of California, Los Angeles Gay Crooks Quest - Discovery Stage Research Projects Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy $965,636
Rumi Scientific CA Ali Brivanlou Quest - Discovery Stage Research Projects Discovery of therapeutics for Huntington’s Disease $1,399,800
University of California, Los Angeles Vaithilingaraja Arumugaswami Quest - Discovery Stage Research Projects Immunization strategies to prevent Zika viral congenital eye and brain disease $2,128,867
University of California, Irvine Brian Cummings Quest - Discovery Stage Research Projects Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0. $1,671,213
City of Hope, Beckman Research Institute Markus Müschen Quest - Discovery Stage Research Projects Lgr5-mediated self-renewal in B cell selection and leukemia-initiation $2,186,520
Stanford University Gary Steinberg Late Stage Preclinical Projects Intraparenchymal NR1 Stem Cell Therapy for Chronic Subcortical Ischemic Stroke $5,300,000
Scaled Biolabs Inc. Justin Cooper-White Quest - Discovery Stage Research Projects A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs $657,528
Cellerant Therapeutics, Inc. Swapna Panuganti Late Stage Preclinical Projects Development of CLT030-ADC, a Leukemic Stem Cell Targeting Antibody-Drug-Conjugate, for Treatment of Acute Myeloid Leukemia $6,863,755
University of California, San Francisco Holger Willenbring Quest - Discovery Stage Research Projects Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis $1,638,389
SanBio, Inc. Bijan Nejadnik Clinical Trial Stage Projects A Double-Blind, Controlled Ph 2b Study of the Safety and Efficacy of Modified Stem Cells in Patients with Chronic Motor Deficit from Ischemic Stroke $19,998,580
University of California, Berkeley Kevin Healy Quest - Discovery Stage Research Projects Human Cardiac Chip for Assessment of Proarrhythmic Risk $899,595
University of California, San Francisco Tippi MacKenzie Clinical Trial Stage Projects In Utero Hematopoietic Stem Cell Transplantation For The Treatment Of Fetuses With Alpha Thalassemia Major $10,906,978
City of Hope, Beckman Research Institute Yuan Chen Quest - Discovery Stage Research Projects A Novel Approach to Eradicate Cancer Stem Cells $1,839,484
Stanford University Mark Mercola Quest - Discovery Stage Research Projects Multipotent Cardiovascular Progenitor Regeneration of the Myocardium after MI $1,809,234
University of California, Davis Deborah Lieu Quest - Discovery Stage Research Projects Microenvironment for hiPSC-derived pacemaking cardiomyocytes $2,042,728
University of Southern California Biju Thomas Inception - Discovery Stage Research Projects A Novel Tissue Engineering Technique to Repair Degenerated Retina $215,133
University of California, San Francisco Sonja Schrepfer Inception - Discovery Stage Research Projects Hypo-immunogenic cardiac patches for myocardial regeneration $235,818
Sanford-Burnham Medical Research Institute Alessandra Sacco Inception - Discovery Stage Research Projects Generation of expandable, self-renewing muscle stem cells for Duchenne Muscular Dystrophy $252,000
Stanford University Helen Blau Inception - Discovery Stage Research Projects Prodrug innovation to target muscle stem cells and enhance muscle regeneration $235,834
University of California, San Diego Tannishtha Reya Inception - Discovery Stage Research Projects Reprogramming human stem cells for blood cell generation $210,060
University of California, Irvine Janet Baulch Inception - Discovery Stage Research Projects An exosome-based translational strategy to mitigate Alzheimer’s disease neuropathology $157,650
American Association of Blood Banks Naynesh Kamani Conference II 15th International Cord Blood Sympsium $30,000
Stanford University Samuel Strober Conference II Third International Workshop on Clinical Tolerance $29,500
University of California, Los Angeles Song Li Conference II The 18th Annual UC System-Wide Bioengineering Symposium $25,000
University of California, San Diego Karen Christman Therapeutic Translational Research Projects Injectable pro-regenerative scaffold for treating symptomatic peripheral artery disease $2,839,317
Stanford University Joseph Wu Tool Translational Research Projects A Novel, Robust and Comprehensive Predictive Tool Using Human Disease-Specific Induced Pluripotent Stem Cells for Preclinical Drug Screening $1,000,000
Caladrius Biosciences Douglas Losordo Clinical Trial Stage Projects Phase 2 Safety and Efficacy Study of CLBS03 Autologous T-Regulatory Cells in Adolescents with Recent Onset Type 1 Diabetes Mellitus $8,568,363
Cedars-Sinai Medical Center Clive Svendsen Clinical Trial Stage Projects Human Neural Progenitors Secreting Glial Cell Line-Derived Neurotrophic Factor (CNS10-NPC-GDNF) for the Treatment of Amyotrophic Lateral Sclerosis $6,154,067
St. Jude Children's Research Hospital Stephen Gottschalk Clinical Trial Stage Projects Lentiviral Gene Therapy for Infants with X-linked Severe Combined Immunodeficiency using Autologous Bone Marrow Stem Cells and Busulfan Conditioning $11,924,780
Cellular Biomedicine Group, Inc. Jack Wang Late Stage Preclinical Projects Allogenic human adipose-derived mesenchymal stem cells for the treatment of knee osteoarthritis $1,200,000
Stanford University Joseph Wu Conference II 2017 Stanford Drug Discovery and Stem Cell Technology Conference $2,359
City of Hope, Beckman Research Institute John Zaia Conference - The 2017 Alpha Stem Cell Clinic Annual Symposium 2nd Annual Symposium of the CIRM Alpha Stem Cell Clinics Network "Alpha Clinics - Making the Future a Reality for Stem Cell-Based Therapies" $79,287
Gladstone Institutes, J. David Deepak Srivastava Quest - Discovery Stage Research Projects Direct Cardiac Reprogramming for Regenerative Medicine $2,400,048
Parkinson's Institute Birgitt Schuele Quest - Discovery Stage Research Projects CRISPR/dCas9 mutant targeting SNCA promoter for downregulation of alpha-synuclein expression as a novel therapeutic approach for Parkinson’s disease $1,288,415
University of California, San Diego Dan Kaufman Quest - Discovery Stage Research Projects Targeted off-the-shelf immunotherapy to treat refractory cancers $1,936,936
University of California, Los Angeles John Chute Quest - Discovery Stage Research Projects Protein tyrosine phosphatase - sigma inhibitors for hematopoietic regeneration $2,116,708
University of California, San Francisco Julie Sneddon Quest - Discovery Stage Research Projects Designing a cellular niche for transplantation of human embryonic stem cell-derived beta cells $2,006,076
Stanford University Matthew Porteus Quest - Discovery Stage Research Projects Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells $1,968,456
University of California, San Diego Alysson Muotri Quest - Discovery Stage Research Projects A treatment for Zika virus infection and neuroprotection efficacy $1,924,524
Stanford University Rosa Bacchetta Quest - Discovery Stage Research Projects GENE EDITING FOR FOXP3 IN HUMAN HSC $984,228
University of California, San Francisco Tejal Desai Quest - Discovery Stage Research Projects Thin Film Encapsulation Devices for Human Stem Cell derived Insulin Producing Cells $1,092,063
Stanford University Roel Nusse Quest - Discovery Stage Research Projects Preclinical development of human hepatocyte progenitor cells for cell therapy $1,651,643
University of California, Irvine Leslie Thompson Quest - Discovery Stage Research Projects hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease $1,650,263
jCyte, Inc Henry Klassen Clinical Trial Stage Projects Phase 2b Clinical Study of Safety and Efficacy of Intravitreal Injection of Retinal Progenitor Cells (jCell) for Treatment of Retinitis Pigmentosa $8,295,750
Stanford University Samuel Strober Clinical Trial Stage Projects Induction of Tolerance to Combined Kidney and Hematopoietic Progenitor Cell Transplants from HLA Haplotype Matched Living Donors $6,653,266
Ankasa Regenerative Therapeutics Ying Zhu Therapeutic Translational Research Projects An autologous somatic stem cell therapy for the treatment of osteonecrosis $2,088,780
University of Southern California Denis Evseenko Therapeutic Translational Research Projects Pluripotent stem cell-derived chondrocytes for articular cartilage repair $2,503,104
Children's Hospital of Oakland Research Institute Mark Walters Therapeutic Translational Research Projects Curing Sickle cell Disease with CRISPR-Cas9 genome editing $4,463,435
Gladstone Institutes, J. David Yadong Huang Therapeutic Translational Research Projects Human iPSC-derived GABAergic Progenitors for Alzheimer’s Disease Treatment $1,900,000
City of Hope, Beckman Research Institute Paul Salvaterra Conference - Manage The SPARK Annual Meeting Manage the 2017 SPARK Annual Meeting $22,555
University of Southern California Justin Ichida Conference II The 7th Annual California ALS research network and PAC10 meeting $10,830
Orchard Therapeutics plc Andrea Spezzi Clinical Trial Stage Projects Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $8,465,745
University of California, Los Angeles Donald Kohn Clinical Trial Stage Projects Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $10,156,925
Cedars-Sinai Medical Center Michael Lewis Clinical Trial Stage Projects Pulmonary Arterial Hypertension Treated with Cardiosphere-Derived Allogeneic Stem Cells $7,354,772
Forty Seven Inc. Mark Chao Clinical Trial Stage Projects A Phase 1b/2 Trial of the Anti-CD47 Antibody Hu5F9-G4 in Combination with Cetuximab in Patients with Solid Tumors and Advanced Colorectal Cancer $10,234,048
San Diego State University Foundation Ralph Feuer Conference - Manage The Bridges Annual Meeting 2017 Bridges Annual Meeting $153,449
Quintiles Consulting, Inc. Thorsten Gorba Translating Center A Translating Center designed to expedite the development and delivery of high quality stem cell therapies to patients $15,000,000
University of California, San Diego Stephanie Cherqui Late Stage Preclinical Projects Ex vivo transduced autologous human CD34+ hematopoietic stem cells for treatment of cystinosis $5,273,189
Midwinter Conference of Immunologists Christel Uittenbogaart Conference II The 2017 Midwinter Conference of Immunologists at Asilomar $5,000
University of California, San Diego Robert Sah Conference II 2016 Tissue Engineering and Regenerative Medicine International Society - Americas (TERMIS-AM) Conference in San Diego, CA on December 11-14, 2016 $40,000
Vitalant Research Institute Shibani Pati Conference II Cellular Therapies and Transfusion Medicine in Trauma and Critical Care - Looking Towards the Future $30,000
Alliance Forum Foundation George Hara Conference II 2016 World Alliance Forum in San Francisco (WAFSF) “US-Japan Innovative Healthcare Technologies Conference” $20,000
Humacyte, Inc. Jeffrey Lawson Clinical Trial Stage Projects A Human Acellular Vessel in Patients Needing Renal Replacement Therapy: A Comparison with ePTFE Grafts as Conduits for Hemodialysis (HUMANITY) $9,999,528
University of California, Los Angeles April Pyle Quest - Discovery Stage Research Projects CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells $2,150,400
Stanford University Hiromitsu Nakauchi Quest - Discovery Stage Research Projects Novel Rejuvenated T Cell Immunotherapy for Lung Cancer $1,968,456
University of California, Berkeley David Schaffer Quest - Discovery Stage Research Projects Scalable, Defined Production of Oligodendrocyte Precursor Cells to Treat Neural Disease and Injury $1,634,055
University of California, Davis David Segal Quest - Discovery Stage Research Projects MSC delivery of an artificial transcription factor to the brain as a treatment for Angelman Syndrome $1,087,572
Scripps Research Institute Jeanne Loring Quest - Discovery Stage Research Projects Autologous cell therapy for Parkinson’s disease using iPSC-derived DA neurons $2,299,786
Gladstone Institutes, J. David Deepak Srivastava Quest - Discovery Stage Research Projects Use of Human iPSC-derived Endothelial Cells for Calcific Aortic Valve Disease Therapeutics $2,400,048
California Institute of Technology David Baltimore Quest - Discovery Stage Research Projects Immunotherapy for HIV infection using engineered hematopoietic stem/progenitor cells $1,576,888
ViaCyte, Inc. Kevin D'Amour Late Stage Preclinical Projects Stem cell-derived islet cell replacement therapy with immunosuppression for high-risk type 1 diabetes $3,544,721
Quintiles Consulting, Inc. Peter Robinson Accelerating Center An Accelerating Center designed to expedite the development and delivery of high quality stem cell therapies to patients $12,000,000
University of California, Los Angeles Sophie Deng Late Stage Preclinical Projects Regeneration of a Normal Corneal Surface by Limbal Stem Cell Therapy $4,244,211
University of California, Los Angeles Brigitte Gomperts Conference - Lung Regenerative Medicine Workshop Stem Cells for Lung Diseases - Overcoming Barriers to Find New Therapies $44,548
Stanford University Albert Wong Therapeutic Translational Research Projects 2nd Generation Vaccine for the Treatment of Glioblastoma $2,929,889
University of California, San Francisco Andrew Brack Inception - Discovery Stage Research Projects Examining the efficacy of GDF11 antibody as a rejuvenator of aged human muscle stem cell capacity and muscle repair . $180,000
University of California, Los Angeles April Pyle Inception - Discovery Stage Research Projects Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells $230,400
University of California, San Diego Alysson Muotri Inception - Discovery Stage Research Projects Reverse transcriptase inhibitors as a novel therapeutic approach for neurological autoimmune disorders $210,060
University of California, Los Angeles Owen Witte Inception - Discovery Stage Research Projects Identification of stem cell surface markers as potential therapeutic targets for advanced prostate cancer $209,160
Stanford University Jeffrey Goldberg Inception - Discovery Stage Research Projects Embryonic Stem Cells for Corneal Endothelial Degeneration $235,836
Vitalant Research Institute Marcus Muench Inception - Discovery Stage Research Projects Modulating Liver Sinusoidal Endothelial Cell Permeability to Enhance Engraftment of Endothelial Cell Progenitors for the Treatment of Hemophilia A $180,000
Children's Hospital of Los Angeles Senta Georgia Inception - Discovery Stage Research Projects Developing a personalized approach to beta cell replacement for patients with a genetic form of diabetes $179,995
University of California, San Diego Karl Wahlin Inception - Discovery Stage Research Projects Microenvironment based optimization of retinal induction using CRISPR-CAS9 reporter pluripotent stem cells as an expandable source of retinal progenitors and photoreceptors. $232,200
University of California, Los Angeles Stanley Carmichael Inception - Discovery Stage Research Projects iPS-Interneuron Transplantation for Neural Repair after Stroke $229,396
Stanford University Bertha Chen Inception - Discovery Stage Research Projects Autologous iPSC-based therapy for radiation induced bladder injury $235,836
University of California, San Diego Dionicio Siegel Inception - Discovery Stage Research Projects New Methods for the Chemical Expansion of Hematopoietic Stem and Progenitor Cells $232,200
Stanford University Philip Beachy Inception - Discovery Stage Research Projects Curing bladder cancer by replacing corrupted urothelium with differentiated hES cells $210,906

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