All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Irvine Magdalene Seiler Therapeutic Translational Research Projects Morphological and functional integration of stem cell derived retina organoid sheets into degenerating retina models $4,769,039
Children's Hospital of Oakland Research Institute Henry Erlich Diagnostic Translational Research Projects Development of a Noninvasive Prenatal Test for Beta-Hemoglobinopathies for Earlier Stem Cell Therapeutic Interventions $1,088,592
University of California, San Francisco Steven Mack Diagnostic Translational Research Projects Development of a Noninvasive Prenatal Test for Beta-Hemoglobinopathies for Earlier Stem Cell Therapeutic Interventions $633,014
University of California, San Francisco Morton Cowan Clinical Trial Stage Projects Gene Transfer for Artemis-Deficient Severe Combined Immunodeficiency Using a Lentiviral Vector to Transduce Autologous CD34 Hematopoietic Stem Cells $12,000,000
Stanford University Crystal Mackall Clinical Trial Stage Projects Phase 1 Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Adults with Recurrent or Refractory B Cell Malignancies $11,034,982
Sangamo BioSciences, Inc. Bettina Cockroft Clinical Trial Stage Projects A Phase 1/2 Study to Assess the Safety, Tolerability, and Efficacy of ST-400 Autologous HSPC Transplant in Transfusion-dependent β-Thalassemia $8,000,000
Fate Therapeutics, Inc. Bob Valamehr Late Stage Preclinical Projects IND enabling development of FT516: A Natural Killer Cell Immunotherapy for Cancer Derived from a Human Inducible Pluripotent Stem Cell $4,000,000
City of Hope, Beckman Research Institute Joseph Rosenthal Clinical Trial Stage Projects Treatment of sickle cell disease by induction of mixed chimerism and immune tolerance using CD4+ T-depleted haploidentical blood stem cell transplant $5,742,180
Medeor Therapeutics, Inc. Daniel Brennan Clinical Trial Stage Projects Cellular Immunotherapy for Induction of Immune Tolerance in HLA Matched Living Donor Kidney Transplant Recipients $11,217,155
International Society for Stem Cell Research Glori Rosenson Conference II ISSCR 2019 Nucleus Forum $24,000
International Society for Stem Cell Research Cathy Vijeh Conference II ISSCR 2019 $50,000
Stanford University Joseph Wu Conference II 2018 Stanford Drug Discovery and Stem Cell Technology Conference $15,000
University of California, Riverside Xiaoping Hu Conference II 19th Annual UC System-wide Bioengineering Symposium $14,536
University of California, Los Angeles John Adams Conference - The 2018 Alpha Stem Cell Clinic Annual Symposium Delivery of Stem Cell Therapeutics to Patients $60,000
University of California, Irvine Leslie Thompson Conference II Stem Cells for Huntington’s Disease (HD) International (SC4HDI) Conference $31,727
Keystone Symposia on Molecular and Cellular Biology Thale Jarvis Conference II iPSCs: A Decade of Progress and Beyond $35,000
University of California, San Francisco David Rowitch Conference II “Myelin Through the Ages: Evolution, Development, Degeneration and Disease” - 2018 Gordon Research Conference (GRC) and Gordon Research Seminar (GRS) $10,000
City of Hope, Beckman Research Institute Saswati Chatterjee Quest - Discovery Stage Research Projects Genome Editing of Sinusoidal Endothelial Stem Cells for Permanent Correction of Hemophilia A $2,182,193
Neurona Therapeutics Cory Nicholas Quest - Discovery Stage Research Projects Development of a Cellular Therapeutic for Treatment of Epilepsy $1,616,536
University of California, San Diego Yang Xu Quest - Discovery Stage Research Projects Development of immune invisible beta cells as a cell therapy for type 1 diabetes through genetic modification of hESCs $1,924,791
ViaCyte, Inc. Alan Agulnick Quest - Discovery Stage Research Projects Preclinical development of an immune evasive islet cell replacement therapy for type 1 diabetes $1,470,987
Stanford University Helen Blau Quest - Discovery Stage Research Projects Stimulating endogenous muscle stem cells to counter muscle atrophy $2,198,687
University of California, San Diego Mark Tuszynski Quest - Discovery Stage Research Projects Neural Stem Cell Relays for Severe Spinal Cord Injury $1,638,900
Stanford University Kyle Loh Quest - Discovery Stage Research Projects Towards hepatocyte cell replacement therapy: developing a renewable source of human hepatocytes from pluripotent stem cells $1,968,456
University of California, Los Angeles April Pyle Quest - Discovery Stage Research Projects Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells $2,148,519
University of California, Los Angeles Stanley Carmichael Quest - Discovery Stage Research Projects iPS Glial Therapy for White Matter Stroke and Vascular Dementia $2,096,095
University of California, San Diego Tannishtha Reya Quest - Discovery Stage Research Projects Targeting Cancer Stem Cells in Hematologic Malignancies $1,960,560
University of California, Los Angeles Scott Kitchen Quest - Discovery Stage Research Projects Engineering Lifelong Cellular Immunity to HIV $1,701,178
University of California, San Francisco Shuvo Roy Quest - Discovery Stage Research Projects Silicon Nanopore Membrane encapsulated enriched-Beta Clusters for Type 1 Diabetes treatment $1,113,000
University of California, Irvine Aileen Anderson Quest - Discovery Stage Research Projects Generation and in vitro profiling of neural stem cell lines to predict in vivo efficacy for chronic cervical spinal cord injury. $1,575,613
University of California, San Diego Catriona Jamieson Therapeutic Translational Research Projects A Splicing Modulator Targeting Cancer Stem Cells in Acute Myeloid Leukemia $2,511,767
University of California, San Diego Dan Kaufman Therapeutic Translational Research Projects Human Embryonic Stem Cell-Derived Natural Killer Cells for Cancer Treatment $4,698,821
University of California, San Francisco Semil Choksi Inception - Discovery Stage Research Projects Generation of human airway stem cells by direct transcriptional reprogramming for disease modeling and regeneration $238,408
Stanford University Guillem Pratx Inception - Discovery Stage Research Projects Novel metabolic labeling method for tracking stem cells to irradiated salivary glands using PET $229,227
University of California, Davis Alyssa Panitch Inception - Discovery Stage Research Projects Development of treatments to improve healing of ischemic wounds $235,099
University of California, San Diego Gerald Morris Inception - Discovery Stage Research Projects Identification of antigenic neo-epitopes from in vitro reprogrammed human tissue precursors for regenerative therapy $193,500
Stanford University Hiromitsu Nakauchi Inception - Discovery Stage Research Projects Optimizing self-renewal signaling kinetics to stabilize ex vivo hematopoietic stem cell expansion $210,906
Human BioMolecular Research Institute John Cashman Inception - Discovery Stage Research Projects Human Pancreatic Cancer Stem Cells: Developing a Novel Drug for Cancer Eradication $303,785
Loma Linda University Julia Unternaehrer-Hamm Inception - Discovery Stage Research Projects Targeting cancer stem cells with nanoparticle RNAi delivery to prevent recurrence and metastasis of ovarian cancer $172,870
University of California, Davis Alice Tarantal Inception - Discovery Stage Research Projects Enhanced Branching Morphogenesis and Pluripotent Cell Lineage Differentiation for Pediatric Regenerative Therapies $235,800
Palo Alto Veterans Institute for Research Ngan Huang Inception - Discovery Stage Research Projects iPSC-Derived Smooth Muscle Progenitors for Treatment of Abdominal Aortic Aneurysm $172,621
Loma Linda University David Baylink Inception - Discovery Stage Research Projects Bone Marrow Targeting of Hematopoietic Stem Cells Engineered to Overexpress 25-OH-VD3 1-α-hydroxylase for Acute Myeloid Leukemia Therapy $178,967
Cedars-Sinai Medical Center Dmitriy Sheyn Inception - Discovery Stage Research Projects IVD rejuvenation using iPSC-derived notochordal cells $241,992
Zenobia Therapeutics Vicki Nienaber Inception - Discovery Stage Research Projects A new phenotypic screening platform that identifies biologically-relevant targets and lead compounds for the treatment of Parkinson’s disease $112,500
University of California, Los Angeles Alireza Moshaverinia Inception - Discovery Stage Research Projects Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration $194,483
Stanford University Anthony Oro Therapeutic Translational Research Projects DEBCT: Genetically Corrected, Induced Pluripotent Cell-Derived Epithelial Sheets for Definitive Treatment of Dystrophic Epidermolysis Bullosa $5,107,353
University of California, San Diego Karl Wahlin Inception - Discovery Stage Research Projects An IPSC cell based model of macular degeneration for drug discovery. $232,200
Calibr Kristen Johnson Clinical Trial Stage Projects Evaluation of the Safety and Tolerability of KA34 in a Phase 1, Double-Blind, Dose Escalation Trial in Patients with Knee Osteoarthritis $8,447,523
Children's Hospital of Los Angeles Michael Pulsipher Clinical Trial Stage Projects Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation (ACES) $4,825,587
Poseida Therapeutics, Inc. Matthew Spear Clinical Trial Stage Projects Clinical Study of T stem cell memory (Tscm)-based CAR-T cells in Patients with Multiple Myeloma $19,813,407
University of California, Davis Gerhard Bauer Conference - Manage The SPARK Annual Meeting The 2018 SPARK Annual Meeting $39,559
Cal State Univ, San Marcos Bianca Mothe Conference - Manage The Bridges Annual Meeting 2018 and 2019 Bridges Annual Meeting $291,622
RUNX1 Research Program Timothy Babich Conference II Living with and Curing RUNX1 FPD/AML Forum $9,500
Alliance Forum Foundation George Hara Conference II 2017 World Alliance Forum in San Francisco (WAFSF) "Healthcare Game Changers" $5,000
University of California, San Francisco Mark Walters Alpha Stem Cell Clinics Network Expansion University of California, San Francisco (UCSF) CIRM Alpha Stem Cell Clinic $5,707,388
Stanford University Matthew Porteus Late Stage Preclinical Projects Genome Editing of Autologous Hematopoietic Stem Cells to Treat Sickle Cell Disease $4,849,363
Nohla Therapeutics Inc Colleen Delaney Clinical Trial Stage Projects A Phase 2 Open-Label, Multi-Center, Randomized, Controlled, Optimal Dose-Finding Study of DCC-UCB in Adults Receiving High Dose Chemotherapy for AML $4,310,000
ViaCyte, Inc. Howard Foyt Clinical Trial Stage Projects Clinical trial of directly vascularized islet cell replacement therapy for high-risk type 1 diabetes $19,752,463
Humacyte, Inc. Jeffrey Lawson Clinical Trial Stage Projects A Phase 3 Study Comparing the Utility of Human Acellular Vessels to Arteriovenous Fistula in Subjects with End-Stage Renal Disease (California Sites) $3,525,000
City of Hope, Beckman Research Institute Christine Brown Clinical Trial Stage Projects Phase I Study of Chimeric Antigen Receptor Engineered Central Memory T cells for the Treatment of Malignant Glioma $12,753,854
University of California, Davis Mehrdad Abedi Alpha Stem Cell Clinics Network Expansion Alpha Stem Cell Clinic for Northern and Central California $7,905,671
Children's Hospital of Oakland Research Institute Mark Walters Alpha Stem Cell Clinics Network Expansion University of California, San Francisco (UCSF) CIRM Alpha Stem Cell Clinic $2,292,611
Angiocrine Bioscience, Inc. Edward Kavalerchik Clinical Trial Stage Projects AB-110-001 Phase 1b Trial and Related Activities to Support Clinical Development of AB-110 $5,000,000
University of California, San Diego Thomas Kipps Clinical Trial Stage Projects A Phase 1b/2a Study of the ROR1-Targeting Monoclonal Antibody, Cirmtuzumab, and the Bruton Tyrosine Kinase Inhibitor, Ibrutinib, in B-Cell Cancers $18,292,674
International Alliance for Biological Standardization Anthony Lubiniecki Conference - Manage a Symposium on Pluripotent Stem Cell Manufacturing Basis of Standardization for Cell Therapies $100,000
University of California, San Diego Ezra Cohen Therapeutic Translational Research Projects Development of ROR1 CAR-T cells to target cancer stem cells in advanced malignancies $5,751,079
BrainStorm Cell Therapeutics Ralph Kern Clinical Trial Stage Projects A Phase 3, Randomized, Placebo-controlled Multicenter Study to Evaluate Efficacy & Safety of Repeated Administrations of NurOwn® in Patients with ALS $15,912,390
JDRF International Esther Latres Conference II JDRF Encapsulation Consortium Fall 2017 Meeting $42,425
Rumi Scientific CA Ali Brivanlou Quest - Discovery Stage Research Projects Discovery of therapeutics for Huntington’s Disease $1,399,800
University of California, Los Angeles Vaithilingaraja Arumugaswami Quest - Discovery Stage Research Projects Immunization strategies to prevent Zika viral congenital eye and brain disease $2,128,867
University of California, Irvine Brian Cummings Quest - Discovery Stage Research Projects Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0. $1,671,213
City of Hope, Beckman Research Institute Markus Müschen Quest - Discovery Stage Research Projects Lgr5-mediated self-renewal in B cell selection and leukemia-initiation $2,186,520
Stanford University Gary Steinberg Late Stage Preclinical Projects Intraparenchymal NR1 Stem Cell Therapy for Chronic Subcortical Ischemic Stroke $5,300,000
Scaled Biolabs Inc. Justin Cooper-White Quest - Discovery Stage Research Projects A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs $657,528
Cellerant Therapeutics, Inc. Swapna Panuganti Late Stage Preclinical Projects Development of CLT030-ADC, a Leukemic Stem Cell Targeting Antibody-Drug-Conjugate, for Treatment of Acute Myeloid Leukemia $6,863,755
University of California, San Francisco Holger Willenbring Quest - Discovery Stage Research Projects Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis $1,638,389
SanBio, Inc. Bijan Nejadnik Clinical Trial Stage Projects A Double-Blind, Controlled Ph 2b Study of the Safety and Efficacy of Modified Stem Cells in Patients with Chronic Motor Deficit from Ischemic Stroke $18,970,000
University of California, Berkeley Kevin Healy Quest - Discovery Stage Research Projects Human Cardiac Chip for Assessment of Proarrhythmic Risk $899,581
University of California, San Francisco Tippi MacKenzie Clinical Trial Stage Projects In Utero Hematopoietic Stem Cell Transplantation For The Treatment Of Fetuses With Alpha Thalassemia Major $10,906,978
City of Hope, Beckman Research Institute Yuan Chen Quest - Discovery Stage Research Projects A Novel Approach to Eradicate Cancer Stem Cells $1,539,935
Stanford University Mark Mercola Quest - Discovery Stage Research Projects Multipotent Cardiovascular Progenitor Regeneration of the Myocardium after MI $1,809,234
University of California, San Diego Yuan Chen Quest - Discovery Stage Research Projects A Novel Approach to Eradicate Cancer Stem Cells $279,977
University of California, Davis Deborah Lieu Quest - Discovery Stage Research Projects Microenvironment for hiPSC-derived pacemaking cardiomyocytes $2,042,438
University of California, Los Angeles Caroline Kuo Quest - Discovery Stage Research Projects Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome $1,512,333
X-Therma Inc. Xiaoxi Wei Quest - Discovery Stage Research Projects Non-Toxic, Highly-Effective Bioinspired Cryoprotectants for On-Demand Stem Cell Therapies $887,883
University of California, Los Angeles Gay Crooks Quest - Discovery Stage Research Projects Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy $965,636
University of Southern California Biju Thomas Inception - Discovery Stage Research Projects A Novel Tissue Engineering Technique to Repair Degenerated Retina $215,133
University of California, San Francisco Sonja Schrepfer Inception - Discovery Stage Research Projects Hypo-immunogenic cardiac patches for myocardial regeneration $235,818
Sanford Burnham Prebys Medical Discovery Institute Alessandra Sacco Inception - Discovery Stage Research Projects Generation of expandable, self-renewing muscle stem cells for Duchenne Muscular Dystrophy $252,000
Stanford University Helen Blau Inception - Discovery Stage Research Projects Prodrug innovation to target muscle stem cells and enhance muscle regeneration $235,834
University of California, San Diego Tannishtha Reya Inception - Discovery Stage Research Projects Reprogramming human stem cells for blood cell generation $210,060
University of California, Irvine Janet Baulch Inception - Discovery Stage Research Projects An exosome-based translational strategy to mitigate Alzheimer’s disease neuropathology $157,650
American Association of Blood Banks Naynesh Kamani Conference II 15th International Cord Blood Sympsium $30,000
Stanford University Samuel Strober Conference II Third International Workshop on Clinical Tolerance $29,500
University of California, Los Angeles Song Li Conference II The 18th Annual UC System-Wide Bioengineering Symposium $25,000
University of California, San Diego Karen Christman Therapeutic Translational Research Projects Injectable pro-regenerative scaffold for treating symptomatic peripheral artery disease $2,839,317
Stanford University Joseph Wu Tool Translational Research Projects A Novel, Robust and Comprehensive Predictive Tool Using Human Disease-Specific Induced Pluripotent Stem Cells for Preclinical Drug Screening $975,000
Cellular Biomedicine Group, Inc. Jack Wang Late Stage Preclinical Projects Allogenic human adipose-derived mesenchymal stem cells for the treatment of knee osteoarthritis $1,200,000
Caladrius Biosciences William Sietsema Clinical Trial Stage Projects Phase 2 Safety and Efficacy Study of CLBS03 Autologous T-Regulatory Cells in Adolescents with Recent Onset Type 1 Diabetes Mellitus $8,175,946
Cedars-Sinai Medical Center Clive Svendsen Clinical Trial Stage Projects Human Neural Progenitors Secreting Glial Cell Line-Derived Neurotrophic Factor (CNS10-NPC-GDNF) for the Treatment of Amyotrophic Lateral Sclerosis $6,154,067

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