All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, San Diego Yang Xu Quest - Discovery Stage Research Projects Development of immune invisible beta cells as a cell therapy for type 1 diabetes through genetic modification of hESCs $1,960,560
ViaCyte, Inc. Alan Agulnick Quest - Discovery Stage Research Projects Preclinical development of an immune evasive islet cell replacement therapy for type 1 diabetes $1,470,987
Stanford University Helen Blau Quest - Discovery Stage Research Projects Stimulating endogenous muscle stem cells to counter muscle atrophy $2,198,687
University of California, San Diego Mark Tuszynski Quest - Discovery Stage Research Projects Neural Stem Cell Relays for Severe Spinal Cord Injury $1,652,677
Stanford University Kyle Loh Quest - Discovery Stage Research Projects Towards hepatocyte cell replacement therapy: developing a renewable source of human hepatocytes from pluripotent stem cells $1,968,456
Human BioMolecular Research Institute John Cashman Inception - Discovery Stage Research Projects Human Pancreatic Cancer Stem Cells: Developing a Novel Drug for Cancer Eradication $303,785
Loma Linda University Julia Unternaehrer-Hamm Inception - Discovery Stage Research Projects Targeting cancer stem cells with nanoparticle RNAi delivery to prevent recurrence and metastasis of ovarian cancer $172,870
University of California, Davis Alice Tarantal Inception - Discovery Stage Research Projects Enhanced Branching Morphogenesis and Pluripotent Cell Lineage Differentiation for Pediatric Regenerative Therapies $235,800
Palo Alto Veterans Institute for Research Ngan Huang Inception - Discovery Stage Research Projects iPSC-Derived Smooth Muscle Progenitors for Treatment of Abdominal Aortic Aneurysm $172,621
Loma Linda University David Baylink Inception - Discovery Stage Research Projects Bone Marrow Targeting of Hematopoietic Stem Cells Engineered to Overexpress 25-OH-VD3 1-α-hydroxylase for Acute Myeloid Leukemia Therapy $178,967
Cedars-Sinai Medical Center Dmitriy Sheyn Inception - Discovery Stage Research Projects IVD rejuvenation using iPSC-derived notochordal cells $241,992
Zenobia Therapeutics Vicki Nienaber Inception - Discovery Stage Research Projects A new phenotypic screening platform that identifies biologically-relevant targets and lead compounds for the treatment of Parkinson’s disease $112,500
University of California, Los Angeles Alireza Moshaverinia Inception - Discovery Stage Research Projects Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration $194,483
Stanford University Anthony Oro Therapeutic Translational Research Projects DEBCT: Genetically Corrected, Induced Pluripotent Cell-Derived Epithelial Sheets for Definitive Treatment of Dystrophic Epidermolysis Bullosa $5,107,353
University of California, San Diego Karl Wahlin Inception - Discovery Stage Research Projects An IPSC cell based model of macular degeneration for drug discovery. $232,200
University of California, San Diego Catriona Jamieson Therapeutic Translational Research Projects A Splicing Modulator Targeting Cancer Stem Cells in Acute Myeloid Leukemia $2,511,767
University of California, San Diego Dan Kaufman Therapeutic Translational Research Projects Human Embryonic Stem Cell-Derived Natural Killer Cells for Cancer Treatment $4,698,821
University of California, San Francisco Semil Choksi Inception - Discovery Stage Research Projects Generation of human airway stem cells by direct transcriptional reprogramming for disease modeling and regeneration $238,408
Stanford University Guillem Pratx Inception - Discovery Stage Research Projects Novel metabolic labeling method for tracking stem cells to irradiated salivary glands using PET $229,227
University of California, Davis Alyssa Panitch Inception - Discovery Stage Research Projects Development of treatments to improve healing of ischemic wounds $235,099
University of California, San Diego Gerald Morris Inception - Discovery Stage Research Projects Identification of antigenic neo-epitopes from in vitro reprogrammed human tissue precursors for regenerative therapy $193,500
Stanford University Hiromitsu Nakauchi Inception - Discovery Stage Research Projects Optimizing self-renewal signaling kinetics to stabilize ex vivo hematopoietic stem cell expansion $210,906
Calibr Kristen Johnson Clinical Trial Stage Projects Evaluation of the Safety and Tolerability of KA34 in a Phase 1, Double-Blind, Dose Escalation Trial in Patients with Knee Osteoarthritis $8,447,523
Children's Hospital of Los Angeles Michael Pulsipher Clinical Trial Stage Projects Antiviral Cellular Therapy for Enhancing T-cell Reconstitution Before or After Hematopoietic Stem Cell Transplantation (ACES) $4,825,587
Poseida Therapeutics, Inc. Matthew Spear Clinical Trial Stage Projects Clinical Study of T stem cell memory (Tscm)-based CAR-T cells in Patients with Multiple Myeloma $19,813,407
University of California, Davis Gerhard Bauer Conference - Manage The SPARK Annual Meeting The 2018 SPARK Annual Meeting $39,559
Cal State Univ, San Marcos Bianca Mothe Conference - Manage The Bridges Annual Meeting 2018 and 2019 Bridges Annual Meeting $291,622
RUNX1 Research Program Timothy Babich Conference II Living with and Curing RUNX1 FPD/AML Forum $9,500
Alliance Forum Foundation George Hara Conference II 2017 World Alliance Forum in San Francisco (WAFSF) "Healthcare Game Changers" $5,000
Children's Hospital of Oakland Research Institute Mark Walters Alpha Stem Cell Clinics Network Expansion University of California, San Francisco (UCSF) CIRM Alpha Stem Cell Clinic $2,292,611
University of California, San Francisco Mark Walters Alpha Stem Cell Clinics Network Expansion University of California, San Francisco (UCSF) CIRM Alpha Stem Cell Clinic $5,707,388
Stanford University Matthew Porteus Late Stage Preclinical Projects Genome Editing of Autologous Hematopoietic Stem Cells to Treat Sickle Cell Disease $4,849,363
Nohla Therapeutics Inc Colleen Delaney Clinical Trial Stage Projects A Phase 2 Open-Label, Multi-Center, Randomized, Controlled, Optimal Dose-Finding Study of DCC-UCB in Adults Receiving High Dose Chemotherapy for AML $4,310,000
ViaCyte, Inc. Howard Foyt Clinical Trial Stage Projects Clinical trial of directly vascularized islet cell replacement therapy for high-risk type 1 diabetes $19,752,463
Humacyte, Inc. Jeffrey Lawson Clinical Trial Stage Projects A Phase 3 Study Comparing the Utility of Human Acellular Vessels to Arteriovenous Fistula in Subjects with End-Stage Renal Disease (California Sites) $3,525,000
City of Hope, Beckman Research Institute Christine Brown Clinical Trial Stage Projects Phase I Study of Chimeric Antigen Receptor Engineered Central Memory T cells for the Treatment of Malignant Glioma $12,753,854
University of California, Davis Mehrdad Abedi Alpha Stem Cell Clinics Network Expansion Alpha Stem Cell Clinic for Northern and Central California $7,905,671
Angiocrine Bioscience, Inc. Paul Finnegan Clinical Trial Stage Projects AB-110-001 Phase 1b Trial and Related Activities to Support Clinical Development of AB-110 $5,000,000
University of California, San Diego Thomas Kipps Clinical Trial Stage Projects A Phase 1b/2a Study of the ROR1-Targeting Monoclonal Antibody, Cirmtuzumab, and the Bruton Tyrosine Kinase Inhibitor, Ibrutinib, in B-Cell Cancers $18,292,674
International Alliance for Biological Standardization Anthony Lubiniecki Conference - Manage a Symposium on Pluripotent Stem Cell Manufacturing Basis of Standardization for Cell Therapies $100,000
University of California, San Diego Ezra Cohen Therapeutic Translational Research Projects Development of ROR1 CAR-T cells to target cancer stem cells in advanced malignancies $5,795,584
BrainStorm Cell Therapeutics Ralph Kern Clinical Trial Stage Projects A Phase 3, Randomized, Placebo-controlled Multicenter Study to Evaluate Efficacy & Safety of Repeated Administrations of NurOwn® in Patients with ALS $15,912,390
JDRF International Esther Latres Conference II JDRF Encapsulation Consortium Fall 2017 Meeting $42,425
Scaled Biolabs Inc. Justin Cooper-White Quest - Discovery Stage Research Projects A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs $657,528
Cellerant Therapeutics, Inc. Swapna Panuganti Late Stage Preclinical Projects Development of CLT030-ADC, a Leukemic Stem Cell Targeting Antibody-Drug-Conjugate, for Treatment of Acute Myeloid Leukemia $6,863,755
University of California, San Francisco Holger Willenbring Quest - Discovery Stage Research Projects Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis $1,638,389
SanBio, Inc. Bijan Nejadnik Clinical Trial Stage Projects A Double-Blind, Controlled Ph 2b Study of the Safety and Efficacy of Modified Stem Cells in Patients with Chronic Motor Deficit from Ischemic Stroke $18,970,000
University of California, Berkeley Kevin Healy Quest - Discovery Stage Research Projects Human Cardiac Chip for Assessment of Proarrhythmic Risk $899,581
University of California, San Francisco Tippi MacKenzie Clinical Trial Stage Projects In Utero Hematopoietic Stem Cell Transplantation For The Treatment Of Fetuses With Alpha Thalassemia Major $10,906,978
City of Hope, Beckman Research Institute Yuan Chen Quest - Discovery Stage Research Projects A Novel Approach to Eradicate Cancer Stem Cells $1,539,935
Stanford University Mark Mercola Quest - Discovery Stage Research Projects Multipotent Cardiovascular Progenitor Regeneration of the Myocardium after MI $1,809,234
University of California, San Diego Yuan Chen Quest - Discovery Stage Research Projects A Novel Approach to Eradicate Cancer Stem Cells $279,977
University of California, Davis Deborah Lieu Quest - Discovery Stage Research Projects Microenvironment for hiPSC-derived pacemaking cardiomyocytes $2,042,728
University of California, Los Angeles Caroline Kuo Quest - Discovery Stage Research Projects Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome $1,512,333
X-Therma Inc. Xiaoxi Wei Quest - Discovery Stage Research Projects Non-Toxic, Highly-Effective Bioinspired Cryoprotectants for On-Demand Stem Cell Therapies $887,883
University of California, Los Angeles Gay Crooks Quest - Discovery Stage Research Projects Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy $965,636
Rumi Scientific CA Ali Brivanlou Quest - Discovery Stage Research Projects Discovery of therapeutics for Huntington’s Disease $1,399,800
University of California, Los Angeles Vaithilingaraja Arumugaswami Quest - Discovery Stage Research Projects Immunization strategies to prevent Zika viral congenital eye and brain disease $2,128,867
University of California, Irvine Brian Cummings Quest - Discovery Stage Research Projects Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0. $1,671,213
City of Hope, Beckman Research Institute Markus Müschen Quest - Discovery Stage Research Projects Lgr5-mediated self-renewal in B cell selection and leukemia-initiation $2,186,520
Stanford University Gary Steinberg Late Stage Preclinical Projects Intraparenchymal NR1 Stem Cell Therapy for Chronic Subcortical Ischemic Stroke $5,300,000
University of Southern California Biju Thomas Inception - Discovery Stage Research Projects A Novel Tissue Engineering Technique to Repair Degenerated Retina $215,133
University of California, San Francisco Sonja Schrepfer Inception - Discovery Stage Research Projects Hypo-immunogenic cardiac patches for myocardial regeneration $235,818
Sanford Burnham Prebys Medical Discovery Institute Alessandra Sacco Inception - Discovery Stage Research Projects Generation of expandable, self-renewing muscle stem cells for Duchenne Muscular Dystrophy $252,000
Stanford University Helen Blau Inception - Discovery Stage Research Projects Prodrug innovation to target muscle stem cells and enhance muscle regeneration $235,834
University of California, San Diego Tannishtha Reya Inception - Discovery Stage Research Projects Reprogramming human stem cells for blood cell generation $210,060
University of California, Irvine Janet Baulch Inception - Discovery Stage Research Projects An exosome-based translational strategy to mitigate Alzheimer’s disease neuropathology $157,650
American Association of Blood Banks Naynesh Kamani Conference II 15th International Cord Blood Sympsium $30,000
Stanford University Samuel Strober Conference II Third International Workshop on Clinical Tolerance $29,500
University of California, Los Angeles Song Li Conference II The 18th Annual UC System-Wide Bioengineering Symposium $25,000
University of California, San Diego Karen Christman Therapeutic Translational Research Projects Injectable pro-regenerative scaffold for treating symptomatic peripheral artery disease $2,839,317
Stanford University Joseph Wu Tool Translational Research Projects A Novel, Robust and Comprehensive Predictive Tool Using Human Disease-Specific Induced Pluripotent Stem Cells for Preclinical Drug Screening $975,000
Cellular Biomedicine Group, Inc. Jack Wang Late Stage Preclinical Projects Allogenic human adipose-derived mesenchymal stem cells for the treatment of knee osteoarthritis $1,200,000
Caladrius Biosciences Douglas Losordo Clinical Trial Stage Projects Phase 2 Safety and Efficacy Study of CLBS03 Autologous T-Regulatory Cells in Adolescents with Recent Onset Type 1 Diabetes Mellitus $8,175,946
Cedars-Sinai Medical Center Clive Svendsen Clinical Trial Stage Projects Human Neural Progenitors Secreting Glial Cell Line-Derived Neurotrophic Factor (CNS10-NPC-GDNF) for the Treatment of Amyotrophic Lateral Sclerosis $6,154,067
St. Jude Children's Research Hospital Stephen Gottschalk Clinical Trial Stage Projects Lentiviral Gene Therapy for Infants with X-linked Severe Combined Immunodeficiency using Autologous Bone Marrow Stem Cells and Busulfan Conditioning $11,924,780
Stanford University Joseph Wu Conference II 2017 Stanford Drug Discovery and Stem Cell Technology Conference $2,359
City of Hope, Beckman Research Institute John Zaia Conference - The 2017 Alpha Stem Cell Clinic Annual Symposium 2nd Annual Symposium of the CIRM Alpha Stem Cell Clinics Network "Alpha Clinics - Making the Future a Reality for Stem Cell-Based Therapies" $79,287
University of California, Irvine Leslie Thompson Quest - Discovery Stage Research Projects hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease $1,650,263
Gladstone Institutes, J. David Deepak Srivastava Quest - Discovery Stage Research Projects Direct Cardiac Reprogramming for Regenerative Medicine $2,392,157
Parkinson's Institute Birgitt Schuele Quest - Discovery Stage Research Projects CRISPR/dCas9 mutant targeting SNCA promoter for downregulation of alpha-synuclein expression as a novel therapeutic approach for Parkinson’s disease $1,288,415
University of California, San Diego Dan Kaufman Quest - Discovery Stage Research Projects Targeted off-the-shelf immunotherapy to treat refractory cancers $1,936,936
University of California, Los Angeles John Chute Quest - Discovery Stage Research Projects Protein tyrosine phosphatase - sigma inhibitors for hematopoietic regeneration $2,116,708
University of California, San Francisco Julie Sneddon Quest - Discovery Stage Research Projects Designing a cellular niche for transplantation of human embryonic stem cell-derived beta cells $2,006,076
Stanford University Matthew Porteus Quest - Discovery Stage Research Projects Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells $1,968,456
University of California, San Diego Alysson Muotri Quest - Discovery Stage Research Projects A treatment for Zika virus infection and neuroprotection efficacy $1,924,524
Stanford University Rosa Bacchetta Quest - Discovery Stage Research Projects GENE EDITING FOR FOXP3 IN HUMAN HSC $984,228
University of California, San Francisco Tejal Desai Quest - Discovery Stage Research Projects Thin Film Encapsulation Devices for Human Stem Cell derived Insulin Producing Cells $1,092,063
Stanford University Roel Nusse Quest - Discovery Stage Research Projects Preclinical development of human hepatocyte progenitor cells for cell therapy $1,651,211
jCyte, Inc Henry Klassen Clinical Trial Stage Projects Phase 2b Clinical Study of Safety and Efficacy of Intravitreal Injection of Retinal Progenitor Cells (jCell) for Treatment of Retinitis Pigmentosa $8,295,750
Stanford University Samuel Strober Clinical Trial Stage Projects Induction of Tolerance to Combined Kidney and Hematopoietic Progenitor Cell Transplants from HLA Haplotype Matched Living Donors $6,653,266
University of California, San Francisco Mark Walters Therapeutic Translational Research Projects Curing Sickle cell Disease with CRISPR-Cas9 genome editing $69,159
Ankasa Regenerative Therapeutics Ying Zhu Therapeutic Translational Research Projects An autologous somatic stem cell therapy for the treatment of osteonecrosis $2,088,780
University of Southern California Denis Evseenko Therapeutic Translational Research Projects Pluripotent stem cell-derived chondrocytes for articular cartilage repair $2,503,104
Children's Hospital of Oakland Research Institute Mark Walters Therapeutic Translational Research Projects Curing Sickle cell Disease with CRISPR-Cas9 genome editing $4,394,276
Gladstone Institutes, J. David Yadong Huang Therapeutic Translational Research Projects Human iPSC-derived GABAergic Progenitors for Alzheimer’s Disease Treatment $1,900,000
City of Hope, Beckman Research Institute Paul Salvaterra Conference - Manage The SPARK Annual Meeting Manage the 2017 SPARK Annual Meeting $22,555
University of Southern California Justin Ichida Conference II The 7th Annual California ALS research network and PAC10 meeting $10,830
Orchard Therapeutics plc Andrea Spezzi Clinical Trial Stage Projects Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $8,465,745
University of California, Los Angeles Donald Kohn Clinical Trial Stage Projects Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $10,156,925

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