Institution RFA PI Name Award Value University of California, Irvine Early Translational IV Magdalene Seiler Restoring vision by sheet transplants of retinal progenitors and retinal pigment epithelium (RPE) derived from human embryonic stem cells (hESCs) $3,998,948 University of California, Irvine Early Translational II leif Havton Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,538,467 University of California, Irvine Basic Biology V Lisa Flanagan Molecular basis of plasma membrane characteristics reflecting stem cell fate potential $994,108 University of California, Irvine Early Translational III Craig Walsh Multiple Sclerosis therapy: Human Pluripotent Stem Cell-Derived Neural Progenitor Cells $4,590,219 University of California, Irvine Disease Team Therapy Development - Research Henry Klassen Retinal progenitor cells for treatment of retinitis pigmentosa $17,144,825 University of California, Irvine Research Training II Peter Donovan Research Training Program II $6,540,127 University of California, Irvine Comprehensive Grant Hans Keirstead hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,158,445 University of California, Irvine SEED Grant Charles Limoli Using human embryonic stem cells to treat radiation-induced stem cell loss: Benefits vs cancer risk $593,242 University of California, Irvine Training Grant I-1 Peter Bryant Stem Cell Research Training Grant $1,935,487 University of California, Irvine New Cell Lines Leslie Thompson New Cell Lines for Huntington's Disease $1,302,526 University of California, Irvine Tools and Technologies III Mathew Blurton-Jones Optimizing the differentiation and expansion of microglial progenitors from human pluripotent stem cells for the study and treatment of neurological disease. $1,147,596 University of California, Irvine Early Translational I Frank LaFerla Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997 University of California, Irvine Basic Biology II Aileen Anderson Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,256,194 University of California, Irvine Basic Biology V Peter Donovan Non-invasive live imaging of stem cell signature metabolic states $540,480 University of California, Irvine SEED Grant Frank LaFerla Development of human ES cell lines as a model system for Alzheimer disease drug discovery $473,963 University of California, Irvine SEED Grant Grant MacGregor Production of Oocytes from Human ES Cells $385,466 University of California, Irvine Shared Labs Peter Donovan Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $3,072,500 University of California, Irvine Basic Biology II Marian Waterman TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal $1,277,101 University of California, Irvine Major Facilities Michael Drake UC Irvine CIRM Institute $27,156,000 University of California, Irvine SEED Grant Vincent Procaccio Mitochondrial Dysfunction in Embryonic Stem Cells $245,582 StemCells, Inc. Disease Team Therapy Development - Research Alexandra Capela Restoration of memory in Alzheimer’s disease: a new paradigm using neural stem cell therapy $8,901,641 University of California, Irvine SEED Grant Michelle Khine Micro Platform for Controlled Cardiac Myocyte Differentiation $156,426 University of California, Irvine Tools and Technologies I Lisa Flanagan Novel Separation of Stem Cell Subpopulations $861,122 University of California, Irvine Early Translational II Brian Cummings Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,517,767 University of California, Irvine Disease Team Planning Henry Klassen Stem cells for neuroprotection of photoreceptors in retinitis pigmentosa $23,537 University of California, Irvine New Faculty II Edwin Monuki Mechanisms in Choroid Plexus Epithelial Development $2,793,395 StemCells, Inc. Disease Team Therapy Development - Research Nobuko Uchida Neural stem cell transplantation for chronic cervical spinal cord injury $0 University of California, Irvine SEED Grant Kyoko Yokomori Derivation and characterization of human ES cells from FSHD embryos $607,200 University of California, Irvine Tools and Technologies I Orhan NALCIOGLU A Multimodality Molecular Imaging Systen (MRSPECT) for in Vivo Stem Cell Tracking $719,798 University of California, Irvine Early Translational II Leslie Thompson A hESc-based Development Candidate for Huntington's Disease $4,045,253 University of California, Irvine Disease Team Planning Leslie Thompson Huntington's Disease Team $41,953 University of California, Irvine Comprehensive Grant Peter Donovan Improved hES Cell Growth and Differentiation $2,381,713 University of California, Irvine SEED Grant Thomas Lane Human Embryonic Stem Cells and Remyelination in a Viral Model of Demyelination $368,081 University of California, Irvine New Faculty I Andrew Putnam A Novel Engineered Niche to Explore the Vasculogenic Potential of Embryonic Stem Cells $395,764 University of California, Irvine Early Translational II Henry Klassen Human retinal progenitor cells as candidate therapy for retinitis pigmentosa $1,803,768 University of California, Irvine Shared Labs Peter Donovan Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $2,107,376 University of California, Irvine Comprehensive Grant Douglas Wallace The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133 University of California, Irvine SEED Grant Brian Cummings The Immunological Niche: Effect of immunosuppressant drugs on stem cell proliferation, gene expression, and differentiation in a model of spinal cord injury. $595,345 University of California, Irvine Tools and Technologies III leif Havton Development of Relevant Pre-clinical Animal Model as a Tool to Evaluate Human Stem Cell-Derived Replacement Therapies for Motor Neuron Injuries and Degenerative Diseases $1,308,711