Proteins Found that Guide Neuron Migration in Brain

Researchers at UC, San Francisco discovered that membrane proteins that form cell to cell connections also have an important role in controlling how neurons migrate in the brain. Understanding neuronal migration is a critical aspect of cell therapy in the nervous system, as replacement cells will need to be directed to their appropriate site of action. This research project is also an example of how funding work in one field moves along work in another. The membrane proteins highlighted in this report had previously been identified in some cancers, and these new observations in neurons provide rationale for targeting them in cancer therapy.

Nature: August 23, 2007
CIRM funding: Laura Elias (T1-00002)

Related Information: Press release, UCSF Institute for Regeneration Medicine

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CIRM's blog is intended to provide information about progress by CIRM grantees, highlight news in stem cell research, and comment on news and events that influence stem cell science whether it's in the U.S. or internationally.

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