Partnering Opportunity for Translational Research Projects


This page contains the program announcement for CIRM's Translational Stage Research Programs. For Information on CIRM's COVID-19 Initiative please click here: Special Call for COVID-19 Projects

The mission of California Institute for Regenerative Medicine (CIRM) is to accelerate stem cell treatments to patients with unmet medical needs.

The objective of this initiative is to create a highly competitive opportunity for promising stem cell-based projects that accelerate completion of translational stage activities necessary for advancement to clinical study or broad end use for any one of the following product types:

  • TRAN 1: Stem cell-based therapeutic candidate (not offered in 2020)
  • TRAN 2: Diagnostic based on stem cells, or critical for stem cell based therapy development or use (not offered in 2020)
  • TRAN 3: Medical device (non-diagnostic) for a stem cell-based therapy or critical for stem cell based therapy development or use (not offered in 2020)
  • TRAN 4: Novel tool that addresses a critical bottleneck to the discovery or development of stem cell-based therapy (not offered in 2020)

Project outcomes, allowable activities, and what qualifies for each of the above product types are described in the corresponding Appendices: A, B, C, and D.  The overall application and review process and general requirements for all product types are described in main document.

Please see the Program Announcement for full details: 

For previous versions of the TRAN Program Announcement, please refer to our Previous Funding Opportunities page.

TRAN application deadline

  • CIRM is not anticipating any Translational Award (TRAN 1,2,3,4) opportunities for the 2020 calendar year.

Future applicants who are interested in reading reviewer feed back on previous TRAN applications, please refer to the review summaries below.


Translational Stage projects seeking additional options for operational support are encouraged to contact The Cell and Gene Therapy Center .

To Submit an Application:

  1. Go to the Grants Management Portal ( and log in with your existing CIRM Username and Password. If you do not have a Username, Click on the "New User" link and follow the instructions to create a CIRM Username and password.
  2. After logging in, click on the Menu tab. Select the tab labeled "Open Programs". Under the section labeled "RFAs and Programs Open for Applications", click on the "Start a Grant Application" link for your selected program.
  3. Complete each section of the Application by clicking on the appropriate link and following the posted instructions. Proposal templates can be located and submitted under the "Uploads" section.
  4. To submit your Application, click on the "Done with Application" button. The "Done with Application" button will be enabled when all of the mandatory sections have been completed. Please note that once this has been selected, you will no longer be able to make changes to your Application.
  5. To confirm submission of your Application, select the tab labeled "Your Applications" and check the table under the section labeled "Your Submitted Applications". You will see your Application number and project title listed once the submission process has been completed.

Latest Press Releases

CIRM-funded research programs are helping turn stem cells into cures. Browse our press release archive below to find out the latest advances. For even more breaking news, visit our blog, The Stem Cellar.