University of California, Davis

Awards to the Institution

Program	Investigator	Award Title	Award Value
Early Translational II	Mark Zern	Liver Cell Transplantation	$4,212,621
Early Translational I	Alice Tarantal	In Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies	$3,143,392
Disease Team Therapy Planning I	Vicki Wheelock	MSC engineered to produce BDNF for the treatment of Huntington's disease	$97,564
Disease Team Therapy Development - Research	Nancy Lane	Treatment of non-traumatic osteonecrosis with endogenous Mesenchymal stem cells	$18,231,356
Tools and Technologies III	J. Leach	Multi-modal technology for non-destructive characterization of bioengineered tissues	$1,574,151
Conference	Alice Tarantal	12th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases	$8,000
Quest - Discovery Stage Research Projects	Deborah Lieu	Microenvironment for hiPSC-derived pacemaking cardiomyocytes	$2,042,438
Clinical Trial Stage Projects	Diana Farmer	The CuRe Trial: Cellular Therapy for In Utero Myelomeningocele Repair	$8,996,474
COMPASS Training Grant	Alice Tarantal	COMPASS Undergraduate Program	$2,909,950
Early Translational II	Roslyn Isseroff	Bone Marrow Mesenchymal Stem Cells to Heal Chronic Diabetic Wounds	$4,629,747
Shared Labs	Alice Tarantal	UC Davis Translational Human Embryonic Stem Cell Shared Research Facility	$1,728,111
Disease Team Therapy Planning I	Mehrdad Abedi	Stem Cell Gene Therapy for HIV in AIDS Lymphoma Patients	$66,880
Disease Team Therapy Development - Research	Vicki Wheelock	MSC engineered to produce BDNF for the treatment of Huntington's disease	$8,924,235
Tools and Technologies III	Laura Marcu	Multimodal platform combining optical and ultrasonic technologies for in vivo nondestructive evaluation of engineered vascular tissue constructs	$1,834,350
Conference	Mark Yarborough	Stem Cell Research for Neurological Disorders: A Case Study in Ethical and Policy Issues in ALS Research	$1,020
Alpha Stem Cell Clinics Network Expansion	Mehrdad Abedi	Alpha Stem Cell Clinic for Northern and Central California	$8,076,421
Quest - Discovery Stage Research Projects	Deborah Lieu	Building a hiPSC-based biopacemaker	$1,260,827
Alpha Stem Cell Clinics Network Expansion	Mehrdad Abedi	Alpha Stem Cell Clinic for Northern and Central California	$7,999,997
SEED Grant	Ebenezer Yamoah	Hair Cells and Spiral Ganglion Neuron Differentiation from Human Embryonic Stem Cells	$458,071
Tools and Technologies I	Alice Tarantal	In Vivo Imaging for the Detection and Quantitation of Transplanted Stem/Progenitor Cells in Nonhuman Primates	$799,350
Disease Team Therapy Planning I	Nancy Lane	Increasing the endogenous mesenchymal stem cells to the bone surface to treat osteoporosis	$107,750
Basic Biology IV	Deborah Lieu	Induction of Pluripotent Stem Cell-Derived Pacemaking Cells	$1,333,689
Preclinical Development Awards	Diana Farmer	Placental Stem Cells for the In Utero Treatment of Spina Bifida	$2,182,146
Conference	Alice Tarantal	11th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases	$16,850
Conference - Manage The SPARK Annual Meeting	Gerhard Bauer	The 2018 SPARK Annual Meeting	$39,391
Quest - Discovery Stage Research Projects	David Segal	AAV9-Cas13 gene therapy for Angelman syndrome	$1,364,903
Therapeutic Translational Research Projects	William Murphy	Overcoming resistance to standard CD19-targeted CAR T using a novel triple antigen targeted vector	$3,869,061
SEED Grant	A. Reddi	hESCs for Articular Cartilage Regeneration	$301,703
Tools and Technologies I	Kit Lam	Discovery of adhesion ligands for pluripotent human stem cells	$834,003
Disease Team Therapy Planning I	Martin Birchall	Airways for Children	$19,800
Creativity Awards	Gerhard Bauer	Internship at a Cutting Edge CIRM-funded Stem Cell Research Facility	$250,064
Preclinical Development Awards	Roslyn Isseroff	Scaffold for dermal regeneration containing pre-conditioned mesenchymal stem cells to heal chronic diabetic wounds	$4,620,144
Conference	Alice Tarantal	9th Annual Gene Therapy Symposium for Heart, Lung and Blood Diseases	$12,000
Inception - Discovery Stage Research Projects	Alyssa Panitch	Development of treatments to improve healing of ischemic wounds	$235,099
Research Training Grant	Jan Nolta	CIRM Cell and Gene Therapy Training Program 2.0	$4,966,300
Late Stage Preclinical Projects	Joseph Anderson	Hematopoetic stem cell gene therapy for the treatment of Tay-Sachs disease	$4,048,253
New Faculty II	Paul Knoepfler	Molecular mechanisms governing hESC and iPS cell self-renewal and pluripotency	$2,157,255
Transplantation Immunology	William Murphy	Donor natural killer (NK) cells as “veto” cells to promote donor-specific tolerance	$1,257,601
Training Grant I-1	Frederick Meyers	Stem Cell Research Training Grant	$1,780,859
New Faculty Physician Scientist	Emanual Maverakis	Tunable hydrogels for therapeutic delivery of multipotent stem cells.	$2,771,903
Clinical Trial Stage Projects	Mehrdad Abedi	Stem Cell Gene Therapy for HIV Mediated by Lentivector Transduced, Pre-selected CD34+ Cells in AIDS lymphoma patients	$8,414,265
Conference	Alice Tarantal	10th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases	$18,300
Inception - Discovery Stage Research Projects	Alice Tarantal	Enhanced Branching Morphogenesis and Pluripotent Cell Lineage Differentiation for Pediatric Regenerative Therapies	$235,800
SPARK	Gerhard Bauer	Internship at a Cutting Edge CIRM-funded Stem Cell Research Facility	$508,750
Quest - Discovery Stage Research Projects	Aijun Wang	In Utero Treatment of Duchenne Muscular Dystrophy with Non-viral Gene Editing	$2,035,544
Comprehensive Grant	Mark Zern	An in vitro and in vivo comparison among three different human hepatic stem cell populations.	$2,251,223
New Faculty I	Chong-Xian Pan	Combinatorial Chemistry Approaches to Develop LIgands against Leukemia Stem Cells	$2,386,409
Early Translational III	Walter Boyd	Extracellular Matrix Bioscaffold Augmented with Human Stem Cells for Cardiovascular Repair	$4,631,754
Disease Team Therapy Development III	Peter Belafsky	Tissue Engineered Recellularized Laryngotracheal Implants	$3,181,162
SPARK	Gerhard Bauer	Internship at a Cutting Edge CIRM-funded Stem Cell Research Facility	$360,573
Conference	Alice Tarantal	13th Annual Gene Therapy Symposium for Heart, Lung, and Blood Diseases	$10,000
Late Stage Preclinical Projects	Diana Farmer	Placental Mesenchymal Stem Cell Augmentation of Fetal Myelomeningocele Repair	$5,615,207
Medical Device Translational Research Projects	Aijun Wang	Living Synthetic Vascular Grafts with Renewable Endothelium	$3,082,579
Basic Biology I	Min Zhao	Directing migration of human stem cells with electric fields	$816,228
Comprehensive Grant	Alice Tarantal	Preclinical Model for Labeling, Transplant, and In Vivo Imaging of Differentiated Human Embryonic Stem Cells	$2,166,757
Research Training II	Frederick Meyers	UC Davis Stem Cell Training Program	$4,838,291
Early Translational III	Kyriacos Athanasiou	Tissue engineered cartilage from autologous, dermis-isolated, adult, stem (DIAS) cells	$1,735,703
Major Facilities	Larry Vanderhoef	UC Davis CIRM Institute	$20,082,400
Therapeutic Translational Research Projects	Joseph Anderson	Overexpression of HexA/HexB by lentivector expression in blood cells to treat Tay-Sachs and Sandhoff disease	$883,174
Conference	Randi Hagerman	Pathways of Neurodevelopmental Disorders (C8)	$29,939
Conference - The 2020 Alpha Stem Cell Clinic Annual Symposium	Mehrdad Abedi	CIRM - Leading the New Era of Living Medicines	$6,738
Clinical Trial Stage Projects	Peter Belafsky	A Double-Blind Randomized Placebo-Controlled Investigation of Autologous Muscle Derived Progenitor Cells for the Treatment of Dysphagia	$11,015,936
Basic Biology II	Eric Kurzrock	Differentiation of Human Embryonic Stem Cells into Urothelium	$849,037
Early Translational I	Jan Nolta	Sustained siRNA production from human MSC to treat Huntingtons Disease and other neurodegenerative disorders	$2,615,674
Disease Team Therapy Planning I	John Laird	Phase I study of IM Injection of VEGF Producing MSC for the Treatment of Critical Limb Ischemia	$76,066
Disease Team Therapy Development - Research	John Laird	Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia	$3,728,384
Shared Labs	Alice Tarantal	UC Davis Translational Human Embryonic Stem Cell Shared Research Facility	$2,000,000
Quest - Discovery Stage Research Projects	David Segal	MSC delivery of an artificial transcription factor to the brain as a treatment for Angelman Syndrome	$1,055,319
Patent Assistance Fund Awards	David McGee	CIRM Patent Prosecution Assistance Fund for Stem Cell Technologies - UCD	$48,595
Conference - Manage The SPARK Annual Meeting	Gerhard Bauer	The 2020 SPARK Annual Meeting	$22,876
Quest - Discovery Stage Research Projects	Kyle Fink	AAV-dCas9 Epigenetic Editing for CDKL5 Deficiency Disorder	$1,429,378
			Total: $195,295,790.00