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Institution
Researcher name
Grant Type
Grant Title
Award Value
University of California, Irvine
Dr. Lisa A Flanagan
Basic Biology V
Molecular basis of plasma membrane characteristics reflecting stem cell fate potential
$994,108
University of California, San Diego
Maike Sander
Basic Biology V
Defining links between chromatin state and developmental competence
$1,050,300
University of Southern California
Dr. Denis A Evseenko Dr.
Basic Biology V
Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes
$735,138
University of California, Los Angeles
Dr. Denis A Evseenko Dr.
Basic Biology V
Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes
$411,330
University of California, San Diego
Miles F Wilkinson
Basic Biology V
New Regulators of Spermatogonial Stem Cells: RHOX Homeobox Transcription Factors
$552,811
University of California, Los Angeles
Dr. Lili Yang
Basic Biology V
Differentiation of Human Hematopoietic Stem Cells into iNKT Cells
$614,400
University of California, San Diego
Dr. Cornelis Murre
Basic Biology V
Epigenetic mechanisms that enforce pluripotency in embryonic stem cells
$1,160,997
University of California, San Diego
Dr. Wei Wang
Basic Biology V
Systems-level discovery of the regulatory mechanisms directing differentiation of hESC
$1,161,000
University of California, San Diego
Dr. Lawrence S. B. Goldstein
Basic Biology V
Elucidating pathways from hereditary Alzheimer mutations to pathological tau phenotypes
$1,050,300
University of California, San Diego
Dr. David A. Cheresh
Basic Biology V
CD61-driven stemness program in epithelial cancer
$1,161,000
University of California, Berkeley
Dr. Andrew Dillin
Basic Biology V
A Requirement for Protein Homeostasis in the Mediation of Stem Cell Health
$1,034,100
Stanford University
Xinnan Wang
Basic Biology V
Misregulated Mitophagy in Parkinsonian Neurodegeneration
$1,174,943
University of Southern California
Dr. Mark S Humayun
Disease Team Therapy Development III
Phase 1 Safety Assessment of CPCB-RPE1, hESC-derived RPE Cell Coated Parylene Membrane Implants, in Patients with Advanced Dry Age Related Macular Degeneration
$16,339,827
University of California, Davis
Dr. Peter C. Belafsky
Disease Team Therapy Development III
Tissue Engineered Recellularized Laryngotracheal Implants
$3,181,162
University of California, Los Angeles
Dr. Dennis J Slamon
Disease Team Therapy Development III
A Phase I dose escalation and expansion clinical trial of the novel first-in-class Polo-like Kinase 4 (PLK4) inhibitor, CFI-400945 in patients with advanced solid tumors
$5,683,693
Stanford University
Professor Irving L Weissman MD
Disease Team Therapy Development III
Clinical Investigation of a Humanized Anti-CD47 Antibody in Targeting Cancer Stem Cells in Hematologic Malignancies and Solid Tumors
$6,505,568
University of California, Los Angeles
Dr. Donald B. Kohn PhD
Disease Team Therapy Development III
Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease
$13,145,465
University of California, San Diego
Thomas J Kipps
Disease Team Therapy Development III
Therapeutic Eradication of Cancer Stem Cells with UC-961 (Cirmtuzumab)
$4,179,598
Sangamo BioSciences, Inc.
Dr. Fyodor D Urnov
Strategic Partnership II
A Treatment For Beta-thalassemia via High-Efficiency Targeted Genome Editing of Hematopoietic Stem Cells
$2,760,540
Human BioMolecular Research Institute
Dr. John R Cashman
Patent Assistance Fund Awards
Intellectual Property for Stem Cell-Related Inventions – HBRI
$50,000
University of California, San Francisco
Karin Immergluck PhD
Patent Assistance Fund Awards
Patent Assistance Fund Proposal – UCSF
$87,257
University of California, Davis
David McGee
Patent Assistance Fund Awards
CIRM Patent Prosecution Assistance Fund for Stem Cell Technologies – UCD
$48,595
University of California, Santa Barbara
Bernadette McCafferty
Patent Assistance Fund Awards
Intellectual Property in Regenerative Bioengineering from CIRM funded research in regenerative medicine at the University of California, Santa Barbara.
$23,564
University of California, Irvine
Ronnie Hanecak
Patent Assistance Fund Awards
CIRM Patent Assistance Fund Application – UCI
$46,155
University of California, Los Angeles
Adele Rennie
Patent Assistance Fund Awards
Patent Assistance Fund – UCLA
$84,973
Stanford University
Katharine Ku
Patent Assistance Fund Awards
Funding for Patent Applications for CIRM-funded Inventions out of Stanford University
$3,525
University of California, San Diego
Dr. Rubén D. Flores
Patent Assistance Fund Awards
Patent Assistance Fund Application – UCSD
$38,162
University of California, San Diego
Dr. Lawrence S. B. Goldstein
Early Translational from Disease Team Conversion
Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis
$4,139,754
University of California, Los Angeles
Dr. Irvin SY Chen
Early Translational from Disease Team Conversion
Development of a humanized mouse model for testing anti-HIV HSPC gene therapy strategies in HIV-1 infected mice.
$1,505,000
University of California, Los Angeles
Dr. Stanley Nelson
Early Translational from Disease Team Conversion
Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy
$1,823,545
University of California, Los Angeles
Dr. Robert Reiter MD
Early Translational IV
Clinical Development of an N-cadherin Antibody to Target Cancer Stem Cells
$4,075,668
Human BioMolecular Research Institute
Dr. John R Cashman
Early Translational IV
Improving Existing Drugs for Long QT Syndrome type 3 (LQT3) by hiPSC Disease-in-Dish Model
$6,361,369
Numerate, Inc.
Dr. John H Griffin
Early Translational IV
Use of human iPSC-derived neurons from Huntington’s Disease patients to develop novel, disease-modifying small molecule structural corrector drug candidates targeting the unique, neurotoxic conformation of mutant huntingtin
$520,015
University of California, Los Angeles
Dr. Jerome A. Zack Ph.D.
Early Translational IV
Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection
$4,925,166
University of California, Los Angeles
Dr. Gerald Lipshutz
Early Translational IV
Gene therapy-corrected autologous hepatocyte-like cells from induced pluripotent stem cells for the treatment of pediatric single enzyme disorders
$1,801,629
University of California, Los Angeles
Dr. Donald B. Kohn PhD
Early Translational IV
Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells
$1,651,884
Salk Institute for Biological Studies
Dr. Inder M. Verma
Early Translational IV
Development of a cell and gene based therapy for hemophilia
$2,298,634
The Scintillon Institute
Dr. Stuart A Lipton
Early Translational IV
Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke
$1,103,185
Sanford Burnham Prebys Medical Discovery Institute
Dr. Stuart A Lipton
Early Translational IV
Programming Human ESC-derived Neural Stem Cells with MEF2C for Transplantation in Stroke
$1,020,815
University of California, San Diego
Professor Alysson R Muotri
Early Translational IV
A drug-screening platform for autism spectrum disorders using human astrocytes
$1,656,456
Cedars-Sinai Medical Center
Dr. Dan Gazit
Early Translational IV
Gene Targeting to Endogenous Stem Cells for Segmental Bone Fracture Healing
$5,121,514
Stanford University
Dr. Michele Calos
Early Translational IV
Engineered iPSC for therapy of limb girdle muscular dystrophy type 2B
$1,876,253
Gladstone Institutes, J. David
Dr. Steve M. Finkbeiner
Early Translational IV
Development of Novel Autophagy Inducers to Block the Progression of and Treat Amyotrophic Lateral Sclerosis (ALS) and Other Neurodegenerative Diseases
$2,049,053
University of California, Irvine
Dr. Magdalene J Seiler
Early Translational IV
Restoring vision by sheet transplants of retinal progenitors and retinal pigment epithelium (RPE) derived from human embryonic stem cells (hESCs)
$3,998,948
ViaCyte, Inc.
Howard Foyt
Strategic Partnership I
Preclinical and clinical testing of a stem cell-based combination product for insulin-dependent diabetes
$9,475,070
Bluebird Bio
David M. Davidson
Strategic Partnership I
A Phase 1/2, Open Label Study Evaluating the Safety and Efficacy of Gene Therapy in Subjects with β-Thalassemia by Transplantation of Autologous Hematopoietic Stem Cells Transduced with the Lentiviral Vector LentiGlobin® Encoding the Human β-A-T87Q-…
$0
FUJIFILM Cellular Dynamics
Deborah Requesens
hPSC Repository
The CIRM Human Pluripotent Stem Cell Biorepository – A Resource for Safe Storage and Distribution of High Quality iPSCs
$9,942,175
Cellular Dynamics International
Dr. Thomas J Novak
hiPSC Derivation
Generation and characterization of high-quality, footprint-free human induced pluripotent stem cell lines from 3,000 donors to investigate multigenic diseases
$16,000,000
University of California, San Diego
Dr. Joseph G. Gleeson
Tissue Collection for Disease Modeling
CIRM Tissue Collection for Neurodevelopmental Disabilities
$830,426
University of California, San Diego
Dr. Kang Zhang M.D.
Tissue Collection for Disease Modeling
Generation of fibroblast cell lines in patients with common blinding eye diseases
$1,034,425
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