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Institution
Researcher name
Grant Type
Grant Title
Award Value
University of California, San Diego
Dan S Kaufman
Quest – Discovery Stage Research Projects
Human iPSC-derived chimeric antigen receptor expressing macrophages for improved cancer treatment.
$1,256,332
Stanford University
Dr. Marius Wernig MD, PhD
Quest – Discovery Stage Research Projects
A universally applicable skin sheet for Dystrophic Epidermolysis Bullosa via next-generation gene editing, iPS cell technology and tissue engineering
$1,229,040
University of California, Davis
Dr. David J Segal PhD
Quest – Discovery Stage Research Projects
AAV9-Cas13 gene therapy for Angelman syndrome
$1,364,903
Stanford University
Dr. Phillip C Yang
Quest – Discovery Stage Research Projects
Hypoxia-specific Production of Exosomes from iPSC-derivatives for Myocardial Repair
$1,418,023
Stanford University
Kathleen M Sakamoto
Quest – Discovery Stage Research Projects
Small Molecules to inhibit Nemo-like Kinase for Treatment of Diamond Blackfan Anemia
$847,923
University of California, Irvine
Munjal M Acharya
Quest – Discovery Stage Research Projects
Stem cell-derived extracellular vesicles to reverse radiation-induced brain injury
$1,064,724
University of California, San Francisco
Dr Marisa Medina
Quest – Discovery Stage Research Projects
iPSCs as a screening tool to predict risk of nonalcoholic fatty liver disease
$813,000
University of California, San Diego
Dr. Tannishtha Reya
Quest – Discovery Stage Research Projects
Targeting Critical Regulators of Cancer Stem Cells
$1,148,264
University of California, Davis
Dr. Deborah K Lieu
Quest – Discovery Stage Research Projects
Building a hiPSC-based biopacemaker
$1,260,827
City of Hope, Beckman Research Institute
Professor Yanhong Shi
Quest – Discovery Stage Research Projects
Combating COVID-19 using human PSC-derived NK cells
$249,998
University of California, San Diego
Tariq M Rana
Quest – Discovery Stage Research Projects
Development of COVID-19 Antiviral Therapy Using Human iPSC-Derived Lung Organoids
$250,000
University of California, Los Angeles
Dr. Thomas Carmichael M.D., Ph.D.
Quest – Discovery Stage Research Projects
Human-induced pluripotent stem cell-derived glial enriched progenitors to treat white matter stroke and vascular dementia.
$250,000
University of California, Irvine
Robert F. Hunt
Quest – Discovery Stage Research Projects
Optimization of a human interneuron cell therapy for traumatic brain injury
$240,000
University of Southern California
Dr. Justin K Ichida
Quest – Discovery Stage Research Projects
Development of a SYF2 antisense oligonucleotide (ASO) treatment for ALS
$222,300
University of California, Irvine
Dr. Mathew Mark Blurton-Jones
Quest – Discovery Stage Research Projects
Transplantation of Pluripotent Stem Cell Derived Microglia for the Treatment of Adult-onset Leukoencephalopathy (HDLS/ALSP)
$214,668
Vitabolus, Inc.
Aline Betancourt
Quest – Discovery Stage Research Projects
The First Orally Delivered Cell Therapy for the Treatment of Inflammatory Bowel Disease
$249,000
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center
Dr Eiji Yoshihara PhD
Quest – Discovery Stage Research Projects
Dual angiogenic and immunomodulating nanotechnology for subcutaneous stem cell derived islet transplantation for the treatment of diabetes
$250,000
University of California, Los Angeles
Dr. Donald B. Kohn PhD
Quest – Discovery Stage Research Projects
Hematopoietic Stem Cell Gene Therapy for X-linked Agammaglobulinemia
$219,230
University of California, San Diego
Dan S Kaufman
Quest – Discovery Stage Research Projects
Human iPSC-derived chimeric antigen receptor-expressing macrophages for cancer treatment
$222,200
Stanford University
Alan G Cheng
Quest – Discovery Stage Research Projects
Modulation of the Wnt pathway to restore inner ear function
$1,389,416
University of California, San Diego
Prof James S Hagood
Quest – Discovery Stage Research Projects
Mesenchymal stem cell extracellular vesicles as therapy for pulmonary fibrosis
$0
University of Southern California
Dr. Neil Segil
Quest – Discovery Stage Research Projects
A screen for drugs to protect against chemotherapy-induced hearing loss, using sensory hair cells derived by direct lineage reprogramming from hiPSCs
$741,574
Salk Institute for Biological Studies
Ronald Mark Evans
Quest – Discovery Stage Research Projects
Therapeutic immune tolerant human islet-like organoids (HILOs) for Type 1 Diabetes
$1,637,209
Gladstone Institutes, J. David
Li Gan
Quest – Discovery Stage Research Projects
Develop iPSC-derived microglia to treat progranulin-deficient Frontotemporal Dementia
$1,547,157
University of California, Los Angeles
Dr. Lili Yang
Quest – Discovery Stage Research Projects
Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer
$1,404,000
University of California, San Diego
Dr. Eric D. Adler MD
Quest – Discovery Stage Research Projects
Genetically Modified Hematopoietic Stem Cells for the Treatment of Danon Disease
$1,393,200
Stanford University
Dr. Katja Weinacht
Quest – Discovery Stage Research Projects
Regenerative Thymic Tissues as Curative Cell Therapy for Patients with 22q11 Deletion Syndrome
$1,251,720
City of Hope, Beckman Research Institute
Dr Saul J Priceman
Quest – Discovery Stage Research Projects
Chimeric Antigen Receptor-Engineered Stem/Memory T Cells for the Treatment of Recurrent Ovarian Cancer
$1,351,174
Stanford University
Dr. Philip Arden Beachy PhD
Quest – Discovery Stage Research Projects
Pluripotent stem cell-derived bladder epithelial progenitors for definitive cell replacement therapy of bladder cancer
$1,265,436
Scripps Research Institute
Stuart A Lipton
Quest – Discovery Stage Research Projects
Drug Development for Autism Spectrum Disorder Using Human Patient iPSCs
$1,827,576
University of California, San Francisco
Dr. Hideho Okada
Quest – Discovery Stage Research Projects
Non-viral reprogramming of the endogenous TCRα locus to direct stem memory T cells against shared neoantigens in malignant gliomas
$900,000
Children’s Hospital of Los Angeles
Dr. Mark R Frey
Quest – Discovery Stage Research Projects
Universal Pluripotent Liver Failure Therapy (UPLiFT)
$1,297,512
University of California, San Diego
Dr. Jonathan H Lin
Quest – Discovery Stage Research Projects
Small Molecule Proteostasis Regulators to Treat Photoreceptor Diseases
$1,153,937
University of California, Irvine
Dr. Aileen J Anderson
Quest – Discovery Stage Research Projects
Generation and in vitro profiling of neural stem cell lines to predict in vivo efficacy for chronic cervical spinal cord injury.
$1,575,613
University of California, San Francisco
Dr. Shuvo Roy
Quest – Discovery Stage Research Projects
Silicon Nanopore Membrane encapsulated enriched-Beta Clusters for Type 1 Diabetes treatment
$1,113,000
University of California, Los Angeles
Dr. Scott G Kitchen
Quest – Discovery Stage Research Projects
Engineering Lifelong Cellular Immunity to HIV
$1,701,178
University of California, San Diego
Dr. Tannishtha Reya
Quest – Discovery Stage Research Projects
Targeting Cancer Stem Cells in Hematologic Malignancies
$1,960,560
University of California, Los Angeles
Dr. Thomas Carmichael M.D., Ph.D.
Quest – Discovery Stage Research Projects
iPS Glial Therapy for White Matter Stroke and Vascular Dementia
$2,086,130
University of California, Los Angeles
Dr. April Pyle Ph.D.
Quest – Discovery Stage Research Projects
Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells
$2,148,519
Stanford University
Dr. Kyle M Loh
Quest – Discovery Stage Research Projects
Towards hepatocyte cell replacement therapy: developing a renewable source of human hepatocytes from pluripotent stem cells
$1,968,456
University of California, San Diego
Mark H Tuszynski
Quest – Discovery Stage Research Projects
Neural Stem Cell Relays for Severe Spinal Cord Injury
$1,638,900
Stanford University
Dr. Helen M Blau
Quest – Discovery Stage Research Projects
Stimulating endogenous muscle stem cells to counter muscle atrophy
$2,198,687
ViaCyte, Inc.
Dr. Alan D. Agulnick
Quest – Discovery Stage Research Projects
Preclinical development of an immune evasive islet cell replacement therapy for type 1 diabetes
$1,470,987
University of California, San Diego
Dr Yang Xu
Quest – Discovery Stage Research Projects
Development of immune invisible beta cells as a cell therapy for type 1 diabetes through genetic modification of hESCs
$1,924,791
Neurona Therapeutics
Dr. Cory R Nicholas
Quest – Discovery Stage Research Projects
Development of a Cellular Therapeutic for Treatment of Epilepsy
$1,616,536
City of Hope, Beckman Research Institute
Dr. Saswati Chatterjee
Quest – Discovery Stage Research Projects
Genome Editing of Sinusoidal Endothelial Stem Cells for Permanent Correction of Hemophilia A
$2,182,193
University of California, Irvine
Dr. Brian J. Cummings
Quest – Discovery Stage Research Projects
Identification and characterization of the optimal human neural stem cell line (hNSC) for the treatment of traumatic brain injury (TBI) 2.0.
$1,671,213
University of California, Los Angeles
Dr. Vaithilingaraja Arumugaswami PhD
Quest – Discovery Stage Research Projects
Immunization strategies to prevent Zika viral congenital eye and brain disease
$2,128,867
Rumi Scientific CA
Ali H. Brivanlou
Quest – Discovery Stage Research Projects
Discovery of therapeutics for Huntington’s Disease
$1,399,800
University of California, Los Angeles
UCLA Gay M Crooks
Quest – Discovery Stage Research Projects
Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy
$965,636
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