Active Awards Portfolio Dashboard
It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.
| Disease | Cell Type | Therapeutic or Technology | Institution | Stage | Project Objective | Details |
|---|---|---|---|---|---|---|
| Diabetes, Metabolic Disorders, Type 1 diabetes | Embryonic Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | Salk |  |
Development Candidate, Proof of Concept | |
| Cancer, Sarcoma, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Muscle Injury, Skeletal/Smooth Muscle disorders | Adult or Tissue Stem Cell | Other Components, Therapeutic Approach | UCSF | |
Development Candidate, Proof of Concept | |
| Skeletal/Smooth Muscle disorders | Embryonic Stem Cell, iPS Cell | Biologic, Exosomes based therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Diabetes, Metabolic Disorders, Type 1 diabetes | Embryonic Stem Cell, iPS Cell | Biologic, Therapeutic Approach | UCLA | |
Development Candidate, Proof of Concept | |
| Bone or Cartilage Disease, Cartilage defect | Adult or Tissue Stem Cell | Biologic, Therapeutic Approach | The Stone Research Foundation for Sports Medicine and Arthritis | |
Development Candidate, Proof of Concept | |
| Bone or Cartilage Disease, Cartilage defect, Osteoarthritis | Embryonic Stem Cell | Donor cell therapy, Other Components, Therapeutic Approach | Scripps Health | |
Development Candidate, Proof of Concept | |
| Metabolic Disorders, Neurological Disorders, Sanfilippo Syndrome/MPS III | iPS Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UC Irvine | |
Development Candidate, Proof of Concept | |
| Huntington's Disease, Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCSD | |
Development Candidate, Proof of Concept | |
| Kidney Disease | Somatic Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCSF | |
Development Candidate, Proof of Concept | |
| Blood Cancer, Cancer, Multiple Myeloma | Somatic Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCSF | |
Development Candidate, Proof of Concept | |
| Multiple Sclerosis, Neurological Disorders | iPS Cell | Small molecule therapy, Therapeutic Approach | Scripps | |
Development Candidate, Proof of Concept | |
| Neurological Disorders, Spinal Cord Injury | iPS Cell | Other Components, Personalized cell therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Heart Disease, Heart failure | Adult or Tissue Stem Cell | Biologic, Nucleic acid based therapy, Therapeutic Approach | Cedars-Sinai | |
Development Candidate, Proof of Concept | |
| Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | Navega Therapeutics | |
Development Candidate, Proof of Concept | |
| Heart Disease | iPS Cell | Model system development, Specific Cell Type Derivation, Technology | Stanford | |
Development Candidate, Proof of Concept | |
| Amyotrophic Lateral Sclerosis, Neurological Disorders | Adult or Tissue Stem Cell | Donor cell therapy, Small molecule therapy, Therapeutic Approach | UCSD | |
Development Candidate, Proof of Concept | |
| Cancer, Ovarian Cancer, Solid Tumors | iPS Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | UCSD | |
Development Candidate, Proof of Concept | |
| Angelman Syndrome, Autism, Neurological Disorders | iPS Cell | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UC Davis | |
Development Candidate, Proof of Concept | |
| Epidermolysis Bullosa, Skin Disease | iPS Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Heart Disease, Heart failure | iPS Cell | Biologic, Exosomes based therapy, Nucleic acid based therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Anemia, Blood Disorders | Adult or Tissue Stem Cell, iPS Cell | Small molecule therapy, Therapeutic Approach | Stanford | |
Development Candidate, Proof of Concept | |
| Liver Disease, Metabolic Disorders | iPS Cell | Diagnostic Test, Technology | UCSF | |
Development Candidate, Proof of Concept | |
| Brain Cancer, Cancer, Neurological Disorders, Solid Tumors | Embryonic Stem Cell | Biologic, Exosomes based therapy, Therapeutic Approach | UC Irvine | |
Development Candidate, Proof of Concept | |
| Cancer, Pancreatic Cancer, Solid Tumors | Cancer Stem Cell | Small molecule therapy, Therapeutic Approach | UCSD | |
Development Candidate, Proof of Concept | |
| Heart Disease | iPS Cell | Donor cell therapy, Therapeutic Approach | UC Davis | |
Development Candidate, Proof of Concept | |
| Liver Disease, Metabolic Disorders | iPS Cell | Donor cell therapy, Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | CHLA | |
Development Candidate, Proof of Concept | |
| iPS Cell | Defined Bioscience, Inc. | Tool/Resources/Bottleneck | ||||
| HEALIOS NA, Inc. | ||||||
| aa Multiple Diseases (Centers & Resoures) | Cell processing & handling, Technology | UC Davis |  |
Tool/Resources/Bottleneck | ||
| Other, Toxicity | iPS Cell | Model system development, Technology | Greenstone Biosciences | |
Tool/Resources/Bottleneck | |
| Heart Disease | iPS Cell | Model system development, Technology | Organos, Inc. | |
Tool/Resources/Bottleneck | |
| Kidney Disease, Kidney Failure | Adult or Tissue Stem Cell | Device, Technology, Therapeutic Approach, Tissue engineering | UC Davis | |
Pre-IND/IDE or Equivalent | |
| Beta Thalassemia, Blood Disorders, Sickle Cell Disease | Adult or Tissue Stem Cell | Diagnostic Test, Technology | UCSF | |
Regulated Lab Test, Ready for Validation | |
| Other | Adult or Tissue Stem Cell | Small molecule therapy, Therapeutic Approach | UCSF | |
Pre-IND/IDE or Equivalent | |
| Ray Therapeutics, INC | ||||||
| Cedars-Sinai | ||||||
| Siren Biotechnology, Inc. | ||||||
| UCLA | ||||||
| UCSD | ||||||
| UCSD | ||||||
| UCLA | ||||||
| Blood Cancer, Cancer, Multiple Myeloma | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach | COH | |
Pre-IND/IDE or Equivalent | |
| UCLA | ||||||
| Corneal Damage, Vision Loss | Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | ||
| Neurological Disorders, Parkinson's Disease | iPS Cell | Personalized cell therapy, Therapeutic Approach | BrainXell Therapeutics | |
Pre-IND/IDE or Equivalent | |
| Blood Disorders | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | ImmunoVec | |
Pre-IND/IDE or Equivalent | |
| HIV/AIDS, Infectious Disease | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Corneal Damage, Vision Loss | Adult or Tissue Stem Cell | Biologic, Exosomes based therapy, Therapeutic Approach | UCLA | |
Pre-IND/IDE or Equivalent | |
| Cancer, Lung Cancer, Solid Tumors | Adult or Tissue Stem Cell | Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach | USC | |
Pre-IND/IDE or Equivalent |