Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Mixed chimerism and acceptance of kidney transplants after immunosuppressive drug withdrawal. 2020 Sci Transl Med
Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids. 2020 Cell Rep Med
mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex. 2020 Elife
Multiexon deletion alleles of ATF6 linked to achromatopsia. 2020 JCI Insight
Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. 2020 Neuron
Neural Stem Cells Improve the Delivery of Oncolytic Chimeric Orthopoxvirus in a Metastatic Ovarian Cancer Model. 2020 Mol Ther Oncolytics
NODAL inhibition promotes differentiation of pacemaker-like cardiomyocytes from human induced pluripotent stem cells. 2020 Stem Cell Res
Northstar enables automatic classification of known and novel cell types from tumor samples. 2020 Sci Rep
Novel C1q receptor-mediated signaling controls neural stem cell behavior and neurorepair. 2020 Elife
Optimization of a syngeneic murine model of bone metastasis. 2020 J Bone Oncol
Outcomes of Limbal Stem Cell Transplant: A Meta-analysis. 2020 JAMA Ophthalmol
PAWI-2 overcomes tumor stemness and drug resistance via cell cycle arrest in integrin beta3-KRAS-dependent pancreatic cancer stem cells. 2020 Sci Rep
Pluripotent Stem Cell-Based Organoid Technologies for Developing Next-Generation Vision Restoration Therapies of Blindness. 2020 J Ocul Pharmacol Ther
Post-Transcriptional Regulation of Homeostatic, Stressed, and Malignant Stem Cells. 2020 Cell Stem Cell
Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells. 2020 Elife
Prrx1 Fibroblasts Represent a Pro-fibrotic Lineage in the Mouse Ventral Dermis. 2020 Cell Rep
Rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR. 2020 Lab Chip
Regulatory T cells promote remyelination in the murine experimental autoimmune encephalomyelitis model of multiple sclerosis following human neural stem cell transplant. 2020 Neurobiol Dis
Resolving the 3D Landscape of Transcription-Linked Mammalian Chromatin Folding. 2020 Mol Cell
Retina Organoid Transplants Develop Photoreceptors and Improve Visual Function in RCS Rats With RPE Dysfunction. 2020 Invest Ophthalmol Vis Sci
Specific targeting of ovarian tumor-associated macrophages by large, anionic nanoparticles. 2020 Proc Natl Acad Sci U S A
Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation. 2020 Elife
Splice Modulation Synergizes Cell Cycle Inhibition. 2020 ACS Chem Biol
Stem Cells and Lung Regeneration. 2020 Am J Physiol Cell Physiol
SUMOylation of E2F1 Regulates Expression of EZH2. 2020 Cancer Res
Surviving Lambs with Myelomeningocele Repaired in utero with Placental Mesenchymal Stromal Cells for 6 Months: A Pilot Study. 2020 Fetal Diagn Ther
Systemic Anti-PD-1 Immunotherapy Results in PD-1 Blockade on T Cells in the Cerebrospinal Fluid. 2020 JAMA Oncol
Targeting macrophage checkpoint inhibitor SIRPalpha for anticancer therapy. 2020 JCI Insight
The antifibrotic adipose-derived stromal cell: Grafted fat enriched with CD74+ adipose-derived stromal cells reduces chronic radiation-induced skin fibrosis. 2020 Stem Cells Transl Med
Three-dimensional bioprinted glioblastoma microenvironments model cellular dependencies and immune interactions. 2020 Cell Res
Tissue Stem Cells: Architects of Their Niches. 2020 Cell Stem Cell
Tumor necrosis factor overcomes immune evasion in p53-mutant medulloblastoma. 2020 Nat Neurosci
Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells. 2020 Cancer Cell
Virus-specific T-cell therapies for patients with primary immune deficiency. 2020 Blood
When glia meet induced pluripotent stem cells (iPSCs). 2020 Mol Cell Neurosci
“Females Are Not Just ‘Protected’ Males”: Sex-Specific Vulnerabilities in Placenta and Brain after Prenatal Immune Disruption. 2019 eNeuro
A Clearing Technique to Enhance Endogenous Fluorophores in Skin and Soft Tissue. 2019 Sci Rep
A Single-Cell Transcriptomic Atlas of Human Neocortical Development during Mid-gestation. 2019 Neuron
A strategic road map to filing a Biologics License Application for a pluripotent stem cell derived therapeutic product 2019 International Alliance for Biological Standardization
Activation of PDGF pathway links LMNA mutation to dilated cardiomyopathy. 2019 Nature
Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme. 2019 Cell Chem Biol
An Improved Two-Step Protocol for Trophoblast Differentiation of Human Pluripotent Stem Cells. 2019 Curr Protoc Stem Cell Biol
An ultrasensitive test for profiling circulating tumor DNA using integrated comprehensive droplet digital detection. 2019 Lab Chip
Anephrogenic phenotype induced by SALL1 gene knockout in pigs. 2019 Sci Rep
Anti-CD117 antibody depletes normal and myelodysplastic syndrome human hematopoietic stem cells in xenografted mice. 2019 Blood
Anti-human CD117 antibody-mediated bone marrow niche clearance in nonhuman primates and humanized NSG mice. 2019 Blood
Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance. 2019 Cell Stem Cell
Atoh1 Directs Regeneration and Functional Recovery of the Mature Mouse Vestibular System. 2019 Cell Rep
Atoh1(+) secretory progenitors possess renewal capacity independent of Lgr5(+) cells during colonic regeneration. 2019 EMBO J
Automated Design of Pluripotent Stem Cell Self-Organization. 2019 Cell Syst