Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Transposable Elements, Inflammation, and Neurological Disease. 2019 Front Neurol
Use of polyvinyl alcohol for chimeric antigen receptor T-cell expansion. 2019 Exp Hematol
Using the Inducible Caspase-9 Suicide-Safeguard System with iPSC and Bioluminescent Tracking. 2019 Methods Mol Biol
V2a interneuron differentiation from mouse and human pluripotent stem cells. 2019 Nat Protoc
Video-based kinetic analysis of calcification in live osteogenic human embryonic stem cell cultures reveals the developmentally toxic effect of Snus tobacco extract. 2019 Toxicol Appl Pharmacol
Wnt signaling inhibition by monensin results in a period of Hippo pathway activation during intestinal adaptation in zebrafish. 2019 Am J Physiol Gastrointest Liver Physiol
Wnt Signaling Is Required for the Maintenance of Human Limbal Stem/Progenitor Cells In Vitro. 2019 Invest Ophthalmol Vis Sci
A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration. 2018 Sci Transl Med
A Case of Corneal Neovascularization Misdiagnosed as Total Limbal Stem Cell Deficiency. 2018 Cornea
A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human hematopoietic stem and progenitor cells. 2018 Nat Med
A molecular cascade modulates MAP1B and confers resistance to mTOR inhibition in human glioblastoma. 2018 Neuro Oncol
A pathway for Parkinson’s Disease LRRK2 kinase to block primary cilia and Sonic hedgehog signaling in the brain. 2018 Elife
A stable mode of bookmarking by TBP recruits RNA polymerase II to mitotic chromosomes. 2018 Elife
A temporal transcriptome and methylome in human embryonic stem cell-derived cardiomyocytes identifies novel regulators of early cardiac development. 2018 Epigenetics
Accurate, strong, and stable reporting of choroid plexus epithelial cells in transgenic mice using a human transthyretin BAC. 2018 Fluids Barriers CNS
Advancing Stem Cell Models of Alpha-Synuclein Gene Regulation in Neurodegenerative Disease. 2018 Front Neurosci
Alpha-synuclein delays mitophagy and targeting Miro rescues neuron loss in Parkinson’s models. 2018 Acta Neuropathol
An interspecies barrier to tetraploid complementation and chimera formation. 2018 Sci Rep
Analysis of cardiomyocyte clonal expansion during mouse heart development and injury. 2018 Nat Commun
Antisecretory Factor-Mediated Inhibition of Cell Volume Dynamics Produces Antitumor Activity in Glioblastoma. 2018 Mol Cancer Res
Artemisitene suppresses tumorigenesis by inducing DNA damage through deregulating c-Myc-topoisomerase pathway. 2018 Oncogene
Arterialized collateral capillaries progress from nonreactive to capable of increasing perfusion in an ischemic arteriolar tree. 2018 Microcirculation
Astrocyte-enriched feeder layers from cryopreserved cells support differentiation of spontaneously active networks of human iPSC-derived neurons. 2018 J Neurosci Methods
Autoimmunity checkpoints as therapeutic targets in B cell malignancies. 2018 Nat Rev Cancer
Autologous Induced Pluripotent Stem Cell-Derived Neurons to Treat Parkinson’s Disease. 2018 Stem Cells Dev
B-Cell-Specific Diversion of Glucose Carbon Utilization Reveals a Unique Vulnerability in B Cell Malignancies. 2018 Cell
Bad wrap: Myelin and myelin plasticity in health and disease. 2018 Dev Neurobiol
Bcl-2 Overexpression Improves Survival and Efficacy of Neural Stem Cell-Mediated Enzyme Prodrug Therapy. 2018 Stem Cells Int
Bioengineering strategies to accelerate stem cell therapeutics. 2018 Nature
Blocking Zika virus vertical transmission. 2018 Sci Rep
Brain Organoids and the Study of Neurodevelopment. 2018 Trends Mol Med
Branched-chain amino acid depletion conditions bone marrow for hematopoietic stem cell transplantation avoiding amino acid imbalance-associated toxicity. 2018 Exp Hematol
Cell Surface N-Glycans Influence Electrophysiological Properties and Fate Potential of Neural Stem Cells. 2018 Stem Cell Reports
Cell Therapy for Chronic Stroke. 2018 Stroke
Cell transplantation strategies for acquired and inherited disorders of peripheral myelin. 2018 Ann Clin Transl Neurol
Changing concepts in hematopoietic stem cells. 2018 Science
Characterization of Gene Alterations following Editing of the beta-Globin Gene Locus in Hematopoietic Stem/Progenitor Cells. 2018 Mol Ther
Chick chorioallantoic membrane assay as an in vivo model to study the effect of nanoparticle-based anticancer drugs in ovarian cancer. 2018 Sci Rep
Chimeric liver transplantation reveals interspecific graft remodelling. 2018 J Hepatol
Co-Emergence of Specialized Endothelial Cells from Embryonic Stem Cells. 2018 Stem Cells Dev
Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development. 2018 Development
Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. 2018 Stem Cell Reports
Concise Review: Human Pluripotent Stem Cells to Produce Cell-Based Cancer Immunotherapy. 2018 Stem Cells
Concise Review: Neural Stem Cell-Mediated Targeted Cancer Therapies. 2018 Stem Cells Transl Med
Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. 2018 J Am Soc Nephrol
Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. 2018 J Am Soc Nephrol
Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning. 2018 J Am Soc Nephrol
Contractile deficits in engineered cardiac microtissues as a result of MYBPC3 deficiency and mechanical overload. 2018 Nat Biomed Eng
Customized Brain Cells for Stroke Patients Using Pluripotent Stem Cells. 2018 Stroke
De novo formation of the biliary system by TGFbeta-mediated hepatocyte transdifferentiation. 2018 Nature