Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD(4)-selective WNT surrogate in mice. 2023 Nat Commun
Transcriptomic Effects on the Mouse Heart Following 30 Days on the International Space Station. 2023 Biomolecules
Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington’s disease mice and innervate the striatum. 2023 Mol Ther
TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. 2023 Proc Natl Acad Sci U S A
Tumor inflammation-associated neurotoxicity. 2023 Nat Med
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes. 2023 Dev Cell
Understanding Fibroblast Heterogeneity in Form and Function. 2023 Biomedicines
Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency. 2023 Sci Rep
A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs. 2022 Nat Commun
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. 2022 Muscle Nerve
A reference human induced pluripotent stem cell line for large-scale collaborative studies. 2022 Cell Stem Cell
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. 2022 Cell Stem Cell
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice. 2022 Cell Rep
Adapting Physiology in Functional Human Islet Organogenesis. 2022 Front Cell Dev Biol
Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells. 2022 Front Cell Neurosci
Advancing preclinical models of psychiatric disorders with human brain organoid cultures. 2022 Mol Psychiatry
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. 2022 Nat Neurosci
An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy. 2022 Cells
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. 2022 Nat Med
Antibody screening data of human midgestation liver cells with a focus on hematopoietic, liver sinusoidal endothelial, and hepatoblast cell-populations. 2022 BMC Res Notes
Biallelic pathogenic variants in COX11 are associated with an infantile-onset mitochondrial encephalopathy. 2022 Hum Mutat
Biomarkers of in vivo limbal stem cell function. 2022 Ocul Surf
Brain organoids, consciousness, ethics and moral status. 2022 Semin Cell Dev Biol
c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. 2022 iScience
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. 2022 Cell
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. 2022 Nat Commun
Cell Morphology as an In Vivo Parameter for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Cloud-controlled microscopy enables remote project-based biology education in underserved Latinx communities. 2022 Heliyon
Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal alpha-Adrenergic Signaling and a Transient Loss of Vascular Tone. 2022 Front Cardiovasc Med
Comment on: Long-Term Outcome After Superficial Keratectomy of the Abnormal Epithelium for Partial Limbal Stem Cell Deficiency. 2022 Am J Ophthalmol
COVID-19 vaccination elicits an evolving, cross-reactive antibody response to epitopes conserved with endemic coronavirus spike proteins. 2022 Cell Rep
Cross-species comparisons reveal resistance of human skeletal stem cells to inhibition by non-steroidal anti-inflammatory drugs. 2022 Front Endocrinol (Lausanne)
Cytokeratin 13 Is a New Biomarker for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Decellularized Adipose Matrices Can Alleviate Radiation-Induced Skin Fibrosis. 2022 Adv Wound Care (New Rochelle)
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting. 2022 Sci Transl Med
Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy. 2022 PLoS Comput Biol
DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis. 2022 Autophagy
Early investigations into improving bowel and bladder function in fetal ovine myelomeningocele repair. 2022 J Pediatr Surg
EED is required for mouse primordial germ cell differentiation in the embryonic gonad. 2022 Dev Cell
Effects of Multi-stage Procurement on the Viability and Function of Human Donor Parathyroid Glands. 2022 J Surg Res
Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration. 2022 Cell Stem Cell
Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair. 2022 Theranostics
Engineering Extracellular Microenvironment for Tissue Regeneration. 2022 Bioengineering (Basel)
Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain. 2022 Cell
Erratum. 2022 Muscle Nerve
Establishment of Chimerism and Organ Transplant Tolerance in Laboratory Animals: Safety and Efficacy of Adaptation to Humans. 2022 Front Immunol
Estrogen-Related Receptor gamma Maintains Pancreatic Acinar Cell Function and Identity by Regulating Cellular Metabolism. 2022 Gastroenterology
Exposure to Cigarette Smoke Impedes Human Osteoblast Differentiation Independently of Nicotine. 2022 Nicotine Tob Res
Gene Expression Analysis in Stem Cell-derived Cortical Neuronal Cultures Using Multi-well SYBR Green Quantitative PCR Arrays. 2022 Bio Protoc
High-level correction of the sickle mutation is amplified in vivo during erythroid differentiation. 2022 iScience