Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Conserved lipid metabolic reprogramming confers hypoxic and aging resilience. 2025 EMBO Rep
Control of Physical and Biochemical Parameters Influencing Exogeneous Cargo Protein Association to Extracellular Vesicles Using Lipid Anchors Enables High Loading and Effective Intracellular Delivery. 2025 J Extracell Biol
Controllable Doping for Tunable and Multimodal Emission in ZnS-Based Mechanoluminescent Nanocrystals. 2025 Nano Lett
Controlling nephron precursor differentiation to generate proximal-biased kidney organoids with emerging maturity. 2025 Nat Commun
Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork. 2025 Transl Vis Sci Technol
CRISPR activation for SCN2A-related neurodevelopmental disorders. 2025 Nature
Culture conditions differentially regulate the inflammatory niche and cellular phenotype of tracheobronchial basal stem cells. 2025 Am J Physiol Lung Cell Mol Physiol
Deep learning the dynamic regulatory sequence code of cardiac organoid differentiation. 2025 bioRxiv
Demographics, Prevalence, and Characteristics of Limbal Stem Cell Deficiency in Southern California. 2025 Cornea
Derivation and Characterization of Isogenic OPA1 Mutant and Control Human Pluripotent Stem Cell Lines. 2025 Cells
Derivation of cardiomyocyte-propelled motile aggregates from stem cells. 2025 bioRxiv
Derivation of functional early gestation decidual natural killer cell subtypes from induced pluripotent stem cells. 2025 bioRxiv
Designing and Evaluating Circadian Experiments on Mouse Skin. 2025 J Invest Dermatol
Developing machine learning-driven multidisease diagnostic platforms using immune repertoire sequencing. 2025 Am J Transplant
Development of iPSC-derived T cells targeting EGFR neoantigens in non-small cell lung cancer. 2025 Mol Ther Methods Clin Dev
Digging Deeper Into Cardiovascular Plasma Proteomics: Opportunities and Limitations of Current Platforms. 2025 Circ Genom Precis Med
Dissecting Gene Regulatory Networks Governing Human Cortical Cell Fate. 2025 bioRxiv
Distinct adipose progenitor cells emerging with age drive active adipogenesis. 2025 Science
Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics. 2025 Neuron
Donor-Targeted Anti-HLA-A2 Antibody Shows Nanogram-Level Efficacy in a Novel GVHD Mouse Model. 2025 bioRxiv
Dosing parameters for grafting human neural stem cells into sites of spinal cord injury. 2025 Exp Neurol
Double-strand break repair pathways differentially affect processing and transduction by dual AAV vectors. 2025 Nat Commun
Dual alpha-globin-truncated erythropoietin receptor knockin restores hemoglobin production in alpha-thalassemia-derived erythroid cells. 2025 Cell Rep
Dysfunctional CD11c(-)CD21(-) extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer. 2025 Sci Transl Med
Editing stem cell genomes at scale to measure variant effects in diverse cell and genetic contexts. 2025 medRxiv
Effect of immunosuppression on hESC-derived retina organoids in vitro and in vivo. 2025 Stem Cell Res Ther
Effects of PDMS culture on stem cell differentiation towards definitive endoderm and hepatocytes. 2025 Acta Biomater
Efficient Retroviral Transduction and Competitive Homing for Investigating GPCR-Mediated T-Cell Localization in Diverse Tissue Microenvironments. 2025 J Vis Exp
eIF3 engages with 3′-UTR termini of highly translated mRNAs. 2025 Elife
Elevated hematopoietic stem cell frequency in mouse alveolar bone marrow. 2025 Stem Cell Reports
Elevated Senescence Markers in Developing Trisomy 21 Human Lungs. 2025 Am J Respir Cell Mol Biol
Engineering filamentous potato virus X as a platform nanotechnology for nucleic acid gene delivery. 2025 Sci Rep
Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis. 2025 Nat Commun
Enhanced durability of a Zika virus self-amplifying RNA vaccine through combinatorial OX40 and 4-1BB agonism. 2025 JCI Insight
Enhanced neuromorphogenesis of neural stem cells via the optimization of physical stimulus-responsive signaling pathways. 2025 Stem Cell Res Ther
Enhanced Parkin-mediated mitophagy mitigates adverse left ventricular remodelling after myocardial infarction: role of PR-364. 2025 Eur Heart J
Epigenetic Upregulation of Carotid Body Angiotensin Signaling Increases Blood Pressure. 2025 Hypertension
Every cell every gene all at once: Systems genetic approaches toward corticogenesis. 2025 Curr Opin Neurobiol
Evidence of neuronal DNA damage in the brains of patients with Rett syndrome. 2025 Dis Model Mech
Evolutionary-scale enzymology enables exploration of a rugged catalytic landscape. 2025 Science
Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors. 2025 Cancer Discov
Exosomes as Future Therapeutic Tools and Targets for Corneal Diseases. 2025 Cells
Expansion of human pluripotent stem cell-induced nephron progenitor cells (iNPCs) and the generation of nephron organoids from iNPCs. 2025 Nat Protoc
F.O.R.W.A.R.D: A Data-Driven Framework for Network-Based Target Prioritization in Drug Discovery. 2025 bioRxiv
Functional Neurogenomics to Dissect Disease Mechanisms Across Models. 2025 Annu Rev Genomics Hum Genet
FXYD2 marks and regulates maturity of beta cells via ion channel-mediated signal transduction. 2025 Nat Commun
Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. 2025 Nat Protoc
Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines. 2025 Stem Cell Res
Genome editing with programmable base editors in human cells. 2025 Methods Enzymol
GFP-on mouse model for interrogation of in vivo gene editing. 2025 Nat Commun