Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Circadian Clock in Muscle Disease Etiology and Therapeutic Potential for Duchenne Muscular Dystrophy. 2024 Int J Mol Sci
Collagen scaffold-seeded iTenocytes accelerate the healing and functional recovery of Achilles tendon defects in a rat model. 2024 Front Bioeng Biotechnol
Comparing fabrication techniques for engineered cardiac tissue. 2024 J Biomed Mater Res A
Conductive Microgel Annealed Scaffolds Enhance Myogenic Potential of Myoblastic Cells. 2024 Adv Healthc Mater
Conserved and divergent features of trophoblast stem cells. 2024 J Mol Endocrinol
Continuous multiplexed phage genome editing using recombitrons. 2024 Nat Biotechnol
CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity. 2024 Cell Stem Cell
Custom-engineered hydrogels for delivery of human iPSC-derived neurons into the injured cervical spinal cord. 2024 Biomaterials
Decellularized Extracellular Matrix Improves Mesenchymal Stromal Cell Spheroid Response to Chondrogenic Stimuli. 2024 Tissue Eng Part A
Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma. 2024 Sci Adv
Dendrite injury triggers neuroprotection in Drosophila models of neurodegenerative disease. 2024 Sci Rep
Development of neuronal timescales in human cortical organoids and rat hippocampus dissociated cultures. 2024 J Neurophysiol
Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity. 2024 Diabetologia
Directed Differentiation of Neurons from Human iPSCs for Modeling Neurological Disorders. 2024 Methods Mol Biol
Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation. 2024 Elife
DNA-guided transcription factor cooperativity shapes face and limb mesenchyme. 2024 Cell
Does vaping increase the likelihood of SARS-CoV-2 infection? Paradoxically yes and no. 2024 Am J Physiol Lung Cell Mol Physiol
Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin. 2024 Sci Adv
Effects of amyloid-beta-mimicking peptide hydrogel matrix on neuronal progenitor cell phenotype. 2024 Acta Biomater
Electroacupuncture may protect pulmonary dysplasia in offspring with perinatal nicotine exposure by altering maternal gut microbiota and metabolites. 2024 Front Microbiol
Engineered Protein Hydrogels as Biomimetic Cellular Scaffolds. 2024 Adv Mater
Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy. 2024 Mol Ther
Engineering programmable material-to-cell pathways via synthetic notch receptors to spatially control differentiation in multicellular constructs. 2024 Nat Commun
EphB2 Signaling Is Implicated in Astrocyte-Mediated Parvalbumin Inhibitory Synapse Development. 2024 J Neurosci
Epididymis-specific RNase A family genes regulate fertility and small RNA processing. 2024 J Biol Chem
Fatty acid oxidation in immune function. 2024 Front Immunol
Frontiers in CAR-T cell therapy for autoimmune diseases. 2024 Trends Pharmacol Sci
Functional outcome of the anterior vaginal wall in a pelvic surgery injury rat model after treatment with stem cell-derived progenitors of smooth muscle cells. 2024 Stem Cell Res Ther
Gene editing improves endoplasmic reticulum-mitochondrial contacts and unfolded protein response in Friedreich’s ataxia iPSC-derived neurons. 2024 Front Pharmacol
Generation of ‘semi-guided’ cortical organoids with complex neural oscillations. 2024 Nat Protoc
Generation of allogeneic CAR-NKT cells from hematopoietic stem and progenitor cells using a clinically guided culture method. 2024 Nat Biotechnol
Generation of antigen-specific mature T cells from RAG1(-/-)RAG2(-/-)B2M(-/-) stem cells by engineering their microenvironment. 2024 Nat Biomed Eng
Glioblastoma Neurovascular Progenitor Orchestrates Tumor Cell Type Diversity. 2024 bioRxiv
H1FOO-DD promotes efficiency and uniformity in reprogramming to naive pluripotency. 2024 Stem Cell Reports
Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells. 2024 ACS Nano
Human anti-PSCA CAR macrophages possess potent antitumor activity against pancreatic cancer. 2024 Cell Stem Cell
Implantation of autologous induced pluripotent stem cell-derived islets provides long-term insulin independence in a patient with type 1 diabetes. 2024 Am J Transplant
Increased mitochondrial mutation heteroplasmy induces aging phenotypes in pluripotent stem cells and their differentiated progeny. 2024 Aging Cell
Induced pluripotent stem cells (iPSCs): molecular mechanisms of induction and applications. 2024 Signal Transduct Target Ther
Inhibition of Pyruvate Oxidation Diminishes Melanoma Progression. 2024 J Invest Dermatol
Integrated Single-Cell Analysis Reveals Spatially and Temporally Dynamic Heterogeneity in Fibroblast States during Wound Healing. 2024 J Invest Dermatol
Integration of Functional Polymers and Biosensors to Enhance Wound Healing. 2024 Adv Healthc Mater
Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses. 2024 bioRxiv
Isolation of Mouse Pancreatic Endothelial Cells. 2024 J Vis Exp
Label-free metabolic optical biomarkers track stem cell fate transition in real time. 2024 Sci Adv
Lentiviral vectors for precise expression to treat X-linked lymphoproliferative disease. 2024 Mol Ther Methods Clin Dev
Locoregional delivery of IL-13Ralpha2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial. 2024 Nat Med
Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility. 2024 Elife
Mechanistic Understanding of Enhancing Bioactivity via Bio-Ionic Liquids Functionalization of Biomaterials 2024 Applied Materials Today
Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism. 2024 Neuron