Modeling brain macrophage biology and neurodegenerative diseases using human iPSC-derived neuroimmune organoids. |
2023 |
Front Cell Neurosci |
Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI. |
2023 |
Res Sq |
Neonatal Cardiovascular-Progenitor-Cell-Derived Extracellular Vesicles Activate YAP1 in Adult Cardiac Progenitor Cells. |
2023 |
Int J Mol Sci |
Neurons require glucose uptake and glycolysis in vivo. |
2023 |
Cell Rep |
Ocular Surface Regeneration by Limbal Stem Cells Therapies: State of the Art, Challenges, and Perspectives. |
2023 |
Stem Cells Transl Med |
OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis. |
2023 |
Proc Natl Acad Sci U S A |
Patient-derived SLC6A1 variant S295L results in an epileptic phenotype similar to haploinsufficient mice. |
2023 |
Epilepsia |
Pharmacological inhibition of CLK2 activates YAP by promoting alternative splicing of AMOTL2. |
2023 |
bioRxiv |
Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition. |
2023 |
bioRxiv |
Preferential FGF18/FGFR activity in pseudoglandular versus canalicular stage human lung fibroblasts. |
2023 |
Front Cell Dev Biol |
Preneoplastic stromal cells promote BRCA1-mediated breast tumorigenesis. |
2023 |
Nat Genet |
Present and Future Modeling of Human Psychiatric Connectopathies With Brain Organoids. |
2023 |
Biol Psychiatry |
Presentation of Human Neural Stem Cell Antigens Drives Regulatory T Cell Induction. |
2023 |
J Immunol |
Profiling of repetitive RNA sequences in the blood plasma of patients with cancer. |
2023 |
Nat Biomed Eng |
Profiling ovarian cancer tumor and microenvironment during disease progression for cell-based immunotherapy design. |
2023 |
iScience |
Protein-encapsulated doxorubicin reduces cardiotoxicity in hiPSC-cardiomyocytes and cardiac spheroids while maintaining anticancer efficacy. |
2023 |
Stem Cell Reports |
PTPN2 Is a Critical Regulator of Ileal Paneth Cell Viability and Function in Mice. |
2023 |
Cell Mol Gastroenterol Hepatol |
PTPN2 regulates bacterial clearance in a mouse model of enteropathogenic and enterohemorrhagic E. coli infection. |
2023 |
JCI Insight |
Purification and functional characterization of novel human skeletal stem cell lineages. |
2023 |
Nat Protoc |
Pushing the boundaries of brain organoids to study Alzheimer’s disease. |
2023 |
Trends Mol Med |
Reversing lysosome-ribosome circuit dysregulation mitigates C9FTD/ALS neurodegeneration and behaviors. |
2023 |
Hum Mol Genet |
RNA editing: Expanding the potential of RNA therapeutics. |
2023 |
Mol Ther |
RNA splicing factor Rbm25 underlies heterogeneous preleukemic clonal expansion in mice. |
2023 |
Blood |
Sensory nerve niche regulates mesenchymal stem cell homeostasis via FGF/mTOR/autophagy axis. |
2023 |
Nat Commun |
Signalling by senescent melanocytes hyperactivates hair growth. |
2023 |
Nature |
Single mRNA detection of Wnt signaling pathway in the human limbus. |
2023 |
Exp Eye Res |
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. |
2023 |
Sci Adv |
Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits. |
2023 |
iScience |
SIX1+PAX3+ identify a progenitor for myogenic lineage commitment from hPSCs. |
2023 |
Development |
Sonogenetic control of multiplexed genome regulation and base editing. |
2023 |
Nat Commun |
Stable expression of large transgenes via the knock-in of an integrase-deficient lentivirus. |
2023 |
Nat Biomed Eng |
Stem Cell-Based Organoid Models of Neurodevelopmental Disorders. |
2023 |
Biol Psychiatry |
Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates. |
2023 |
Elife |
Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes. |
2023 |
Breast Cancer Res |
Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production. |
2023 |
bioRxiv |
T-allo10 Infusion after αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Improved Immune Reconstitution in the Absence of Severe GvHD |
2023 |
Transplantation and Cellular Therapy |
Targeted Proteomic Profiling Revealed Roles of Small GTPases during Osteogenic Differentiation. |
2023 |
Anal Chem |
Targeting the ADPKD methylome using nanoparticle-mediated combination therapy. |
2023 |
APL Bioeng |
Thalamocortical circuits in generalized epilepsy: Pathophysiologic mechanisms and therapeutic targets. |
2023 |
Neurobiol Dis |
The sinoatrial node extracellular matrix promotes pacemaker phenotype and protects automaticity in engineered heart tissues from cyclic strain. |
2023 |
Cell Rep |
Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD(4)-selective WNT surrogate in mice. |
2023 |
Nat Commun |
Transcriptomic Effects on the Mouse Heart Following 30 Days on the International Space Station. |
2023 |
Biomolecules |
Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington’s disease mice and innervate the striatum. |
2023 |
Mol Ther |
TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. |
2023 |
Proc Natl Acad Sci U S A |
Tumor inflammation-associated neurotoxicity. |
2023 |
Nat Med |
Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes. |
2023 |
Dev Cell |
Understanding Fibroblast Heterogeneity in Form and Function. |
2023 |
Biomedicines |
Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency. |
2023 |
Sci Rep |
A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs. |
2022 |
Nat Commun |
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. |
2022 |
Muscle Nerve |