[(18)F]FDG-PET and [(18)F]MPPF-PET are brain biomarkers for the creatine transporter Slc6a8 loss of function mutation. |
2025 |
Sci Rep |
Adipose tissue ageing: implications for metabolic health and lifespan. |
2025 |
Nat Rev Endocrinol |
ADMET-AI Enables Interpretable Predictions of Drug-Induced Cardiotoxicity. |
2025 |
Circulation |
Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies. |
2025 |
Nat Commun |
An SSTR2-somatostatin chemotactic axis drives T cell progenitor homing to the intestines. |
2025 |
Nat Immunol |
Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork. |
2025 |
Transl Vis Sci Technol |
Derivation and Characterization of Isogenic OPA1 Mutant and Control Human Pluripotent Stem Cell Lines. |
2025 |
Cells |
Distinct adipose progenitor cells emerging with age drive active adipogenesis. |
2025 |
Science |
Effect of immunosuppression on hESC-derived retina organoids in vitro and in vivo. |
2025 |
Stem Cell Res Ther |
Efficient Retroviral Transduction and Competitive Homing for Investigating GPCR-Mediated T-Cell Localization in Diverse Tissue Microenvironments. |
2025 |
J Vis Exp |
Every cell every gene all at once: Systems genetic approaches toward corticogenesis. |
2025 |
Curr Opin Neurobiol |
Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors. |
2025 |
Cancer Discov |
Functional Neurogenomics to Dissect Disease Mechanisms Across Models. |
2025 |
Annu Rev Genomics Hum Genet |
Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. |
2025 |
Nat Protoc |
Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines. |
2025 |
Stem Cell Res |
Genome editing with programmable base editors in human cells. |
2025 |
Methods Enzymol |
Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. |
2025 |
NPJ Precis Oncol |
Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury. |
2025 |
Brain Behav Immun |
On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery. |
2025 |
Biosensors (Basel) |
Rapamycin enhances CAR-T control of HIV replication and reservoir elimination in vivo. |
2025 |
J Clin Invest |
The UCSC Genome Browser database: 2025 update. |
2025 |
Nucleic Acids Res |
Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction. |
2025 |
Nat Commun |
A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis. |
2024 |
Elife |
A facilitatory role of astrocytes in axonal regeneration after acute and chronic spinal cord injury. |
2024 |
Exp Neurol |
A fibroblast-dependent TGF-beta1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis. |
2024 |
J Clin Invest |
A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases. |
2024 |
Nat Commun |
A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS. |
2024 |
Nature |
A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease. |
2024 |
Mol Ther Methods Clin Dev |
A Panoramic View of Cell Population Dynamics in Mammalian Aging. |
2024 |
bioRxiv |
A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. |
2024 |
Proc Natl Acad Sci U S A |
Acid-degradable lipid nanoparticles enhance the delivery of mRNA. |
2024 |
Nat Nanotechnol |
AMPK Drives both Glycolytic and Oxidative Metabolism in Murine and Human T Cells During Graft-versus-host Disease. |
2024 |
Blood Adv |
An age-progressive platelet differentiation path from hematopoietic stem cells causes exacerbated thrombosis. |
2024 |
Cell |
An Endothelial Cell Is Not Simply an Endothelial Cell. |
2024 |
Stem Cells Dev |
An improved method for generating human spinal cord neural stem cells. |
2024 |
Exp Neurol |
Antigen-Specific T Cell Receptor Discovery for Treating Progressive Multifocal Leukoencephalopathy. |
2024 |
bioRxiv |
Antisense oligonucleotide therapy in an individual with KIF1A-associated neurological disorder. |
2024 |
Nat Med |
Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment. |
2024 |
Nat Commun |
CAR-T cell therapy targeting surface expression of TYRP1 to treat cutaneous and rare melanoma subtypes. |
2024 |
Nat Commun |
Cell type mapping reveals tissue niches and interactions in subcortical multiple sclerosis lesions. |
2024 |
Nat Neurosci |
Comparing fabrication techniques for engineered cardiac tissue. |
2024 |
J Biomed Mater Res A |
Conserved and divergent features of trophoblast stem cells. |
2024 |
J Mol Endocrinol |
CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity. |
2024 |
Cell Stem Cell |
Custom-engineered hydrogels for delivery of human iPSC-derived neurons into the injured cervical spinal cord. |
2024 |
Biomaterials |
Defining metabolic flexibility in hair follicle stem cell induced squamous cell carcinoma. |
2024 |
Sci Adv |
Disease modeling and pharmacological rescue of autosomal dominant retinitis pigmentosa associated with RHO copy number variation. |
2024 |
Elife |
DNA-guided transcription factor cooperativity shapes face and limb mesenchyme. |
2024 |
Cell |
Early-life stress triggers long-lasting organismal resilience and longevity via tetraspanin. |
2024 |
Sci Adv |
Engineered Protein Hydrogels as Biomimetic Cellular Scaffolds. |
2024 |
Adv Mater |
Engineering allorejection-resistant CAR-NKT cells from hematopoietic stem cells for off-the-shelf cancer immunotherapy. |
2024 |
Mol Ther |