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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
University of California, San Francisco Mitchel Berger Disease Team Research I Stem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM) $19,162,435
University of Southern California Mark Humayun Disease Team Research I Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) $18,904,916
University of California, San Diego Lawrence Goldstein Disease Team Research I Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $10,857,762
Calimmune, Inc. Geoff Symonds Disease Team Research I GENE-MODIFIED HEMATOPOIETIC STEM/PROGENITOR CELL BASED THERAPY FOR HIV DISEASE $8,278,722
University of California, Los Angeles Irvin Chen Early Translational from Disease Team Conversion HPSC based therapy for HIV disease using RNAi to CCR5. $1,505,000
University of California, San Diego Dennis Carson Disease Team Research I Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT) $19,999,826
Stanford University Alfred Lane Disease Team Research I iPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa $11,709,574
Beckman Research Institute of City of Hope Karen Aboody Disease Team Research I Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials $18,015,429
Stanford University Gary Steinberg Disease Team Research I Embryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke $20,000,000
University of California, Los Angeles Dennis Slamon Disease Team Research I THERAPEUTIC OPPORTUNITIES TO TARGET TUMOR INITIATING CELLS IN SOLID TUMORS $19,979,660
University of California, Los Angeles Donald Kohn Disease Team Research I Stem Cell Gene Therapy for Sickle Cell Disease $9,212,365
Stanford University Irving Weissman Disease Team Research I Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells $19,999,996
ViaCyte, Inc. Allan Robins Disease Team Research I Cell Therapy for Diabetes $22,999,937
Cedars-Sinai Medical Center Eduardo Marbán Disease Team Research I Autologous cardiac-derived cells for advanced ischemic cardiomyopathy $5,560,232
Beckman Research Institute of City of Hope John Zaia Disease Team Research I ZIinc Finger Nuclease-Based Stem Cell Therapy for AIDS $14,583,187
University of California, Los Angeles Irvin Chen Disease Team Research I HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
Beckman Research Institute of City of Hope Michael Barish Research Training II Research Training Program in Stem Cell Biology $2,500,143
Scripps Research Institute Jeanne Loring Shared Labs Center for hESC Research $3,828,751
Stanford University Renee Reijo Pera Shared Labs Center for Human Embryonic Stem Cell Research and Education $5,819,047
University of California, Los Angeles Stanley Nelson Disease Team Therapy Development - Research Combination Therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $6,000,000
University of California, San Diego Karl Willert Shared Labs Enhancing Facilities for Genetic Manipulation and Engineering of Human Embryonic Stem Cells $3,711,102
Stanford University Judith Shizuru Disease Team Therapy Development - Research A monoclonal antibody that depletes blood stem cells and enables chemotherapy free transplants $20,000,000
Buck Institute for Age Research Xianmin Zeng Shared Labs CIRM Shared Research Laboratory for Stem Cells and Aging $5,883,026
University of California, Los Angeles Antoni Ribas Disease Team Therapy Development - Research Genetic Re-programming of Stem Cells to Fight Cancer $19,999,563
The J. David Gladstone Institutes Deepak Srivastava Shared Labs CIRM Shared Human Embryonic Stem Cell Core Laboratory $2,621,345
Children's Hospital of Los Angeles David Warburton Research Training II Stem Cell Training Grant $5,103,441
University of California, Davis Nancy Lane Disease Team Therapy Development - Research Treatment of osteoporosis with endogenous Mesenchymal stem cells $19,999,867
University of California, Santa Cruz Lindsay Hinck Shared Labs Shared Stem Cell Facility $3,588,740
The J. David Gladstone Institutes Robert Mahley Research Training II CIRM Scholars Program $5,111,047
University of California, Davis John Laird Disease Team Therapy Development - Research Phase I study of IM Injection of VEGF-Producing MSC for the Treatment of Critical Limb Ischemia $14,184,595
University of California, Los Angeles Owen Witte Shared Labs CIRM Shared Research Laboratories $3,740,497
University of California, Berkeley Ellen Robey Research Training II Interdisciplinary Training in Stem Cell Biology, Engineering and Medicine $6,902,189
University of California, Davis Vicki Wheelock Disease Team Therapy Development - Research MSC engineered to produce BDNF for the treatment of Huntington's disease $18,950,061
The Salk Institute for Biological Studies Inder Verma Shared Labs Shared viral vector facility for genetic manipulation of human ES cell $4,316,515
Scripps Research Institute Ulrich Mueller Research Training II Training Stem Cell Researchers at the Chemistry-Biology Interface $4,058,362
Cedars-Sinai Medical Center Clive Svendsen Disease Team Therapy Development - Research Progenitor Cells Secreting GDNF for the Treatment of ALS $17,842,617
University of California, Irvine Peter Donovan Shared Labs Regional Human Embryonic Stem Cell Shared Research Laboratory and Stem Cell Techniques Course $5,572,979
University of California, Irvine Peter Donovan Research Training II Research Training Program II $6,827,148
StemCells, Inc. Alexandra Capela Disease Team Therapy Development - Research Restoration of memory in Alzheimer’s disease: a new paradigm using neural stem cell therapy $20,000,000
Children's Hospital of Los Angeles David Warburton Shared Labs hESC Facility $3,756,666
University of California, San Francisco Susan Fisher Research Training II Training Program in Stem Cell Research $7,946,605
StemCells, Inc. Nobuko Uchida Disease Team Therapy Development - Research Neural stem cell transplantation for chronic cervical spinal cord injury $20,000,000
University of Southern California Andrew McMahon Shared Labs Center for Stem Cell and Regenerative Medicine: Shared Research Laboratory and Course in Current Protocols in Human Embryonic Stem Cell Research $5,355,969
University of California, San Diego Sylvia Evans Research Training II Interdisciplinary Stem Cell Training Program $7,890,588
University of California, Irvine Henry Klassen Disease Team Therapy Development - Research Retinal progenitor cells for treatment of retinitis pigmentosa $17,306,668
University of California, San Francisco Linda Giudice Shared Labs Shared Research and Teaching Laboratory: a Non-Federal Human Embryonic Stem Cell Resource for the Bay Area Community $5,546,877
University of California, Santa Cruz David Haussler Research Training II CIRM Training Program in Systems Biology of Stem cells $4,591,616
Capricor, Inc Rachel Smith Disease Team Therapy Development - Research Allogeneic Cardiac-Derived Stem Cells for Patients Following a Myocardial Infarction $19,782,136
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $3,161,329
The Salk Institute for Biological Studies Juan Carlos Izpisua Belmonte Research Training II Training in the Biology of Human Embryonic Stem Cells and Emerging Technologies II $3,062,677
University of California, Davis Alice Tarantal Shared Labs Translational Human Embryonic Stem Cell Shared Research Facility $3,709,631
University of California, Santa Barbara Dennis Clegg Research Training II Training Program in Stem Cell Biology and Engineering $2,451,273
University of California, Berkeley David Schaffer Shared Labs Human Embryonic Stem Cell Shared Research Laboratory $2,929,237
Stanford University Renee Reijo Pera Research Training II CIRM Training Program $7,974,291
University of California, Riverside Prudence Talbot Shared Labs A Stem Cell Core Facility for Studying Human Embryonic Stem Cell Differentiation $3,658,353
Buck Institute for Age Research David Greenberg Research Training II CIRM Research Training Program in Stem Cells and Aging $3,178,692
Sanford-Burnham Medical Research Institute Evan Snyder Shared Labs Collaborative Laboratory for Human Embryonic Stem Cell Research $4,762,725
University of Southern California Robert Maxson Research Training II CIRM Stem Cell Biology Training Program $6,162,053
Stanford University Joseph Wu Disease Team Therapy Development - Research Human Embryonic Stem Cell-Derived Cardiomyocytes for Patients with End Stage Heart Failure $19,999,899
Sanford-Burnham Medical Research Institute Mark Mercola Research Training II Type III CIRM Stem Cell Research Training Program $2,856,694
University of California, Davis Frederick Meyers Research Training II Stem Cell Training Program $7,358,024
University of California, Los Angeles Kenneth Dorshkind Research Training II CIRM Research Training Program II $7,982,293
Beckman Research Institute of City of Hope Yanhong Shi Basic Biology IV Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,367,172
University of California, Los Angeles Kathrin Plath Basic Biology IV Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
University of California, San Diego Maike Sander Basic Biology IV Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,391,400
The J. David Gladstone Institutes Sheng Ding Basic Biology IV A new paradigm of lineage-specific reprogramming $1,708,560
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology IV Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells $1,582,606
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,382,400
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
The J. David Gladstone Institutes Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,506,420
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
The J. David Gladstone Institutes Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,708,560
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
Stanford University Ben Barres Basic Biology IV Phenotyping Human Astrocytes in Health and Disease $1,385,517
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
Stanford University Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,195,811
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,393,200
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,285,214
University of California, Berkeley Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
Stanford University Michael Cleary Basic Biology IV Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells $1,244,455
University of California, Davis Deborah Lieu Basic Biology IV Induction of Pluripotent Stem Cell-Derived Pacemaking Cells $1,334,880
University of California, San Francisco Miguel Ramalho-Santos Basic Biology IV Genetic dissection of human cellular reprogramming to pluripotency $1,184,883
Buck Institute for Age Research Deepak Lamba Basic Biology IV 3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis $1,526,319
University of California, San Francisco Jeremy Reiter Basic Biology IV Modeling disease in human embryonic stem cells using new genetic tools $1,387,800
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,250,251
University of California, San Francisco Emmanuelle Passegue New Faculty II Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults $2,274,368
University of Southern California Qilong Ying New Faculty II Mechanisms Underlying the Diverse Functions of STAT3 in Embryonic Stem Cell Fate Regulation $2,413,650
University of California, Los Angeles Antoni Ribas New Faculty II Stem Cells for Immune System Regeneration to Fight Cancer $3,247,000
San Diego State University Ricardo Zayas New Faculty II The molecular basis underlying adult neurogenesis during regeneration and tissue renewal $1,725,830
The J. David Gladstone Institutes Benoit Bruneau New Faculty II Induction of cardiogenesis in pluripotent cells via chromatin remodeling factors $2,847,600
University of California, Los Angeles Brigitte Gomperts New Faculty II Stem Cells in Lung Cancer $2,556,572
Ludwig Institute for Cancer Research Bing Ren New Faculty II Mechanisms of chromatin dynamics at enhancers during ES cell differentiation $1,726,564
University of California, San Diego Shyni Varghese New Faculty II A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
University of California, San Francisco Robert Blelloch New Faculty II Mechanisms of small RNA regulation in early embryonic development $3,204,897
Total:
$672,250,163.00

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