All CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
University of California, Los Angeles Lili Yang Therapeutic Translational Research Projects HSC-Engineered Off-The-Shelf CAR-iNKT Cell Therapy for Multiple Myeloma $5,949,651
University of California, Los Angeles Cristina Puig Saus Therapeutic Translational Research Projects CAR-Tnm cell therapy for melanoma targeting TYRP-1 $5,904,462
University of California, Los Angeles Donald Kohn Quest - Discovery Stage Research Projects Hematopoietic Stem Cell Gene Therapy for X-linked Agammaglobulinemia $219,230
University of California, Los Angeles Stanley Carmichael Quest - Discovery Stage Research Projects Human-induced pluripotent stem cell-derived glial enriched progenitors to treat white matter stroke and vascular dementia. $250,000
University of California, Los Angeles Lili Yang Discovery Research Projects Battling COVID-19 Using Off-The-Shelf HSC-Engineered iNKT Cells $250,000
University of California, Los Angeles Song Li Discovery Research Projects Biomaterial vaccine to enhance the formation of SARS-CoV-2-specific T memory stem cells $149,916
University of California, Los Angeles Vaithilingaraja Arumugaswami Therapeutic Translational Research Projects COVID-19 Antiviral Therapy to Block Direct Cell Injury and Associated Tissue Damage $349,999
University of California, Los Angeles Caroline Kuo Progression Award - Discovery Stage Research Projects Evaluation of Gene Therapy Approaches for Autosomal Recessive Hyper IgE Syndrome Due to Mutations in DOCK8 $234,000
University of California, Los Angeles Brigitte Gomperts Discovery Research Projects Identifying a lead compound for COVID19 using high throughput screening with lung stem cell organoids $149,998
University of California, Los Angeles Gay Crooks Discovery Research Projects Stem cell-based rapid identification of SARS-CoV-2 T cell epitopes and T cell receptors for therapeutic use $126,692
University of California, Los Angeles Sophie Deng Clinical Trial Stage Projects Safety and Feasibility of Cultivated Autologous Limbal Stem Cells for Limbal Stem Cell Deficiency $10,301,486
University of California, Los Angeles Caroline Kuo Therapeutic Translational Research Projects Ex Vivo Gene Editing of Human Hematopoietic Stem Cells for the Treatment of X-Linked Hyper-IgM Syndrome $4,896,628
University of California, Los Angeles Yvonne Chen Therapeutic Translational Research Projects BCMA/CS1 Bispecific CAR-T Cell Therapy to Prevent Antigen Escape in Multiple Myeloma $3,176,805
University of California, Los Angeles Theodore Nowicki Clinical Trial Stage Projects Genetic Modification of Stem Cells and T cells to Activate the Immune System to Target Solid Tumors $4,693,839
University of California, Los Angeles Steven Schwartz Therapeutic Translational Research Projects Clinical Translation of Autologous Regenerative Cell Therapy for Blindness $5,068,026
University of California, Los Angeles Lili Yang Quest - Discovery Stage Research Projects Preclinical Development of An HSC-Engineered Off-The-Shelf iNKT Cell Therapy for Cancer $1,404,000
University of California, Los Angeles Steven Dubinett Clinical Trial Stage Projects A phase I trial of intratumoral administration of CCL21-gene modified dendritic cell (DC) combined with intravenous pembrolizumab for advanced NSCLC $10,955,315
University of California, Los Angeles John Adams Conference - The 2018 Alpha Stem Cell Clinic Annual Symposium Delivery of Stem Cell Therapeutics to Patients $60,000
University of California, Los Angeles April Pyle Quest - Discovery Stage Research Projects Identification and Generation of Long Term Repopulating Human Muscle Stem Cells from Human Pluripotent Stem Cells $2,148,519
University of California, Los Angeles Stanley Carmichael Quest - Discovery Stage Research Projects iPS Glial Therapy for White Matter Stroke and Vascular Dementia $2,096,095
University of California, Los Angeles Scott Kitchen Quest - Discovery Stage Research Projects Engineering Lifelong Cellular Immunity to HIV $1,701,178
University of California, Los Angeles Alireza Moshaverinia Inception - Discovery Stage Research Projects Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration $194,483
University of California, Los Angeles Gay Crooks Quest - Discovery Stage Research Projects Platform Technology for Pluripotent Stem Cell-Derived T cell Immunotherapy $965,636
University of California, Los Angeles Vaithilingaraja Arumugaswami Quest - Discovery Stage Research Projects Immunization strategies to prevent Zika viral congenital eye and brain disease $2,128,867
University of California, Los Angeles Caroline Kuo Quest - Discovery Stage Research Projects Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome $1,512,333
University of California, Los Angeles Song Li Conference II The 18th Annual UC System-Wide Bioengineering Symposium $25,000
University of California, Los Angeles John Chute Quest - Discovery Stage Research Projects Protein tyrosine phosphatase - sigma inhibitors for hematopoietic regeneration $2,116,708
University of California, Los Angeles Donald Kohn Clinical Trial Stage Projects Efficacy and safety of cryopreserved autologous CD34+ HSC transduced with EFS lentiviral vector encoding for human ADA gene in ADA-SCID subjects $10,156,925
University of California, Los Angeles April Pyle Quest - Discovery Stage Research Projects CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells $2,150,400
University of California, Los Angeles Sophie Deng Late Stage Preclinical Projects Regeneration of a Normal Corneal Surface by Limbal Stem Cell Therapy $4,244,211
University of California, Los Angeles Brigitte Gomperts Conference - Lung Regenerative Medicine Workshop Stem Cells for Lung Diseases - Overcoming Barriers to Find New Therapies $44,548
University of California, Los Angeles Stanley Carmichael Inception - Discovery Stage Research Projects iPS-Interneuron Transplantation for Neural Repair after Stroke $229,396
University of California, Los Angeles Arjun Deb Inception - Discovery Stage Research Projects Targeting progenitors in scar tissue to reduce chronic scar burden $230,400
University of California, Los Angeles Bennett Novitch Inception - Discovery Stage Research Projects Organoid Modeling of Human Cortical Microcircuits $208,916
University of California, Los Angeles April Pyle Inception - Discovery Stage Research Projects Novel Platforms to Enhance In Vivo Delivery of Skeletal Muscle Progenitor Cells from Human Pluripotent Stem Cells $230,400
University of California, Los Angeles Owen Witte Inception - Discovery Stage Research Projects Identification of stem cell surface markers as potential therapeutic targets for advanced prostate cancer $209,160
University of California, Los Angeles Peter Butler Therapeutic Translational Research Projects Personalized Cell Therapy for Diabetes $1,494,896
University of California, Los Angeles Lili Yang Therapeutic Translational Research Projects Stem Cell-Based iNKT Cell Therapy for Cancer $6,956,775
University of California, Los Angeles Donald Kohn Conference II Primary Immune Deficiency Treatment Consortium (PIDTC) Annual Scientific Workshop $29,807
University of California, Los Angeles Donald Kohn Clinical Trial Stage Projects A Phase I/II, Non Randomized, Multicenter, Open-Label Study of G1XCGD (Lentiviral Vector Transduced CD34+ Cells) in Patients With X-Linked Chronic Granulomatous Disease $7,083,364
University of California, Los Angeles Hanna Mikkola Tools and Technologies III A suite of engineered human pluripotent stem cell lines to facilitate the generation of hematopoietic stem cells $1,382,400
University of California, Los Angeles James Dunn Tools and Technologies III Skin-derived precursor cells for the treatment of enteric neuromuscular dysfunction $1,044,423
University of California, Los Angeles Carla Koehler Tools and Technologies III A small molecule tool for reducing the malignant potential in reprogramming human iPSCs and ESCs $1,283,900
University of California, Los Angeles Leif Havton Tools and Technologies III Development of a Relevant Pre-Clinical Animal Model as a Tool to Evaluate Human Stem Cell-Derived Replacement Therapies for Motor Neuron Injuries and Degenerative Diseases $1,308,711
University of California, Los Angeles John Adams Alpha Stem Cell Clinics UCLA-UCI Alpha Stem Cell Clinic (ASCC) Consortium $8,000,000
University of California, Los Angeles John Chute Research Leadership Niche-Focused Research: Discovery & Development of Hematopoietic Regenerative Factors $4,645,297
University of California, Los Angeles Lili Yang Basic Biology V Differentiation of Human Hematopoietic Stem Cells into iNKT Cells $614,400
University of California, Los Angeles Denis Evseenko Basic Biology V Promoting survival and countering hypertrophy of pluripotent stem cell (PSC)-derived chondrocytes $411,330
University of California, Los Angeles Bennett Novitch Basic Biology V In vitro modeling of human motor neuron disease $1,148,758
University of California, Los Angeles Samantha Butler Basic Biology V Assessing the mechanism by which the Bone Morphogenetic Proteins direct stem cell fate $515,730
University of California, Los Angeles Donald Kohn Disease Team Therapy Development III Clinical Trial of Stem Cell Gene Therapy for Sickle Cell Disease $13,145,465
University of California, Los Angeles Dennis Slamon Disease Team Therapy Development III A Phase I dose escalation and expansion clinical trial of the novel first-in-class Polo-like Kinase 4 (PLK4) inhibitor, CFI-400945 in patients with advanced solid tumors $5,683,693
University of California, Los Angeles Dana Jones Conference 7th CA/HSCI Junior PI Conference: Stem Cells 2.0 $2,500
University of California, Los Angeles Robert Reiter Early Translational IV Clinical Development of an N-cadherin Antibody to Target Cancer Stem Cells $4,075,668
University of California, Los Angeles Zack Jerome Early Translational IV Stem Cell Programming With Chimeric Antigen Receptors to Eradicate HIV Infection $4,925,166
University of California, Los Angeles Donald Kohn Early Translational IV Beta-Globin Gene Correction of Sickle Cell Disease in Hematopoietic Stem Cells $1,651,884
University of California, Los Angeles Gerald Lipshutz Early Translational IV Gene therapy-corrected autologous hepatocyte-like cells from induced pluripotent stem cells for the treatment of pediatric single enzyme disorders $1,801,629
University of California, Los Angeles Brigitte Gomperts Tissue Collection for Disease Modeling Using human induced pluripotent stem cells to improve our understanding of Idiopathic Pulmonary Fibrosis $811,231
University of California, Los Angeles Tatiana Segura Conference 2013 Materials Research Society (MRS) Spring Meeting Symposium "Design of Cell Instructive Materials" $4,000
University of California, Los Angeles Ali Nsair New Faculty Physician Scientist Human Induced Pluripotent Stem Cell-Derived Cardiovascular Progenitor Cells for Cardiac Cell Therapy. $2,316,894
University of California, Los Angeles Reza Ardehali New Faculty Physician Scientist Preclinical evaluation of human embryonic stem cell-derived cardiovascular progenitors in a large animal model $2,930,388
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
University of California, Los Angeles Kathrin Plath Basic Biology IV Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
University of California, Los Angeles Antoni Ribas Disease Team Therapy Development - Research Genetic Re-programming of Stem Cells to Fight Cancer $14,144,221
University of California, Los Angeles Stanley Nelson Early Translational from Disease Team Conversion Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $1,823,545
University of California, Los Angeles Antoni Ribas Disease Team Therapy Planning I Genetic Re-programming of Stem Cells to Fight Cancer $97,785
University of California, Los Angeles Stanley Nelson Disease Team Therapy Planning I Combination therapy to Enhance Antisense Mediated Exon Skipping for Duchenne Muscular Dystrophy $68,947
University of California, Los Angeles Martina Wiedau-Pazos Conference California ALS Summit 2011 $13,300
University of California, Los Angeles Adele Rennie Patent Assistance Fund Awards Patent Assistance Fund - UCLA $84,973
University of California, Los Angeles Gay Crooks Basic Biology III Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,252,857
University of California, Los Angeles Yi Sun Basic Biology III Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
University of California, Los Angeles Ali Nsair Basic Biology III Characterization and Engineering of the Cardiac Stem Cell Niche $1,127,741
University of California, Los Angeles Kathrin Plath Basic Biology III Discovery of mechanisms that control epigenetic states in human reprogramming and pluripotent cells $1,364,598
University of California, Los Angeles William Lowry Basic Biology III Molecular determinants of accurate differentiation from human pluripotent stem cells $677,115
University of California, Los Angeles Shuo Lin Basic Biology III Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,378,781
University of California, Los Angeles Stanley Carmichael Tools and Technologies II Development of a Hydrogel Matrix for Stem Cell Growth and Neural Repair after Stroke $1,825,613
University of California, Los Angeles Richard Gatti Tools and Technologies II Use of hiPSCs to develop lead compounds for the treatment of genetic diseases $1,833,054
University of California, Los Angeles Martin Martin Tools and Technologies II Pluripotent and Somatic Stem Cell Models to Study Inherited Diarrheal Disorders $1,783,250
University of California, Los Angeles Irvin Chen Conference Stem Cells: A New Avenue of HIV Research and New Approaches to HIV Treatment $24,456
University of California, Los Angeles Sophie Deng Early Translational II Regeneration of Functional Human Corneal Epithelial Progenitor Cells $697,507
University of California, Los Angeles Noriyuki Kasahara Early Translational II Stem cell-based carriers for RCR vector delivery to glioblastoma $3,340,625
University of California, Los Angeles Sophie Deng Early Translational II Regeneration of Functional Human Corneal Epithelial Progenitor Cells $1,524,947
University of California, Los Angeles Bruno Peault Early Translational II Harnessing native fat-residing stem cells for bone regeneration $5,359,076
University of California, Los Angeles Leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $75,628
University of California, Los Angeles Douglas Black Basic Biology II Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,344,562
University of California, Los Angeles Yong Kim Basic Biology II Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
University of California, Los Angeles Benhur Lee Basic Biology II The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
University of California, Los Angeles Gay Crooks Transplantation Immunology Engineering Thymic Regeneration to Induce Tolerance $1,235,445
University of California, Los Angeles Dennis Slamon Disease Team Research I Therapeutic Opportunities To Target Tumor Initiating Cells in Solid Tumors $19,979,660
University of California, Los Angeles Donald Kohn Disease Team Research I Stem Cell Gene Therapy for Sickle Cell Disease $8,833,695
University of California, Los Angeles Irvin Chen Early Translational from Disease Team Conversion Development of a humanized mouse model for testing anti-HIV HSPC gene therapy strategies in HIV-1 infected mice. $1,505,000
University of California, Los Angeles Irvin Chen Disease Team Research I HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
University of California, Los Angeles Bennett Novitch Basic Biology I Molecular Characterization of hESC and hIPSC-Derived Spinal Motor Neurons $1,229,922
University of California, Los Angeles Michael Teitell Basic Biology I Mitochondrial Metabolism in hESC and hiPSC Differentiation, Reprogramming, and Cancer $1,323,029
University of California, Los Angeles Robb Maclellan Basic Biology I Human Cardiovascular Progenitors, their Niches and Control of Self-renewal and Cell Fate $917,667
University of California, Los Angeles Luisa Iruela-Arispe Basic Biology I Molecular Characterization and Functional Exploration of Hemogenic Endothelium $1,371,477
University of California, Los Angeles Gabriel Travis Early Translational I Development of a Stem Cell-based Transplantation Strategy for Treating Age-related Macular Degeneration $5,487,136
University of California, Los Angeles Kenneth Dorshkind Research Training II UCLA CIRM Research Training Program II $7,790,488
University of California, Los Angeles Hsian-Rong Tseng Tools and Technologies I Microfluidic Platform for Screening Chemically Defined Conditions that Facilitate Clonal Expansion of Human Pluripotent Stem Cells $914,096
University of California, Los Angeles Michael Phelps Tools and Technologies I Novel Tools and Technologies for Translational PET Imaging of Cell-based Therapies $914,039

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