Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
[(18)F]FDG-PET and [(18)F]MPPF-PET are brain biomarkers for the creatine transporter Slc6a8 loss of function mutation. 2025 Sci Rep
Acholinebio-ionicliquid-functionalized gelatin methacryloyl hydrogel for chronic wound healing 2025 European Polymer Journal
Adipose tissue ageing: implications for metabolic health and lifespan. 2025 Nat Rev Endocrinol
ADMET-AI Enables Interpretable Predictions of Drug-Induced Cardiotoxicity. 2025 Circulation
Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies. 2025 Nat Commun
An SSTR2-somatostatin chemotactic axis drives T cell progenitor homing to the intestines. 2025 Nat Immunol
Biological tendon regeneration, are we almost there or is it still a stretch? 2025 Regen Med
Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork. 2025 Transl Vis Sci Technol
Derivation and Characterization of Isogenic OPA1 Mutant and Control Human Pluripotent Stem Cell Lines. 2025 Cells
Distinct adipose progenitor cells emerging with age drive active adipogenesis. 2025 Science
Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics. 2025 Neuron
Dosing parameters for grafting human neural stem cells into sites of spinal cord injury. 2025 Exp Neurol
Double-strand break repair pathways differentially affect processing and transduction by dual AAV vectors. 2025 Nat Commun
Effect of immunosuppression on hESC-derived retina organoids in vitro and in vivo. 2025 Stem Cell Res Ther
Efficient Retroviral Transduction and Competitive Homing for Investigating GPCR-Mediated T-Cell Localization in Diverse Tissue Microenvironments. 2025 J Vis Exp
eIF3 engages with 3′-UTR termini of highly translated mRNAs. 2025 Elife
Elevated Senescence Markers in Developing Trisomy 21 Human Lungs. 2025 Am J Respir Cell Mol Biol
Epigenetic Upregulation of Carotid Body Angiotensin Signaling Increases Blood Pressure. 2025 Hypertension
Every cell every gene all at once: Systems genetic approaches toward corticogenesis. 2025 Curr Opin Neurobiol
Evidence of neuronal DNA damage in the brains of patients with Rett syndrome. 2025 Dis Model Mech
Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors. 2025 Cancer Discov
Functional Neurogenomics to Dissect Disease Mechanisms Across Models. 2025 Annu Rev Genomics Hum Genet
FXYD2 marks and regulates maturity of beta cells via ion channel-mediated signal transduction. 2025 Nat Commun
Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. 2025 Nat Protoc
Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines. 2025 Stem Cell Res
Genome editing with programmable base editors in human cells. 2025 Methods Enzymol
Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate. 2025 Genes Dev
Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. 2025 NPJ Precis Oncol
Implantation of engineered adipocytes suppresses tumor progression in cancer models. 2025 Nat Biotechnol
Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction. 2025 bioRxiv
Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury. 2025 Brain Behav Immun
On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery. 2025 Biosensors (Basel)
Rapamycin enhances CAR-T control of HIV replication and reservoir elimination in vivo. 2025 J Clin Invest
Reversible proliferative arrest induced by rapid depletion of RNase MRP. 2025 Nat Commun
Spinal Cord Injury in Real Time: Intra-Operative Ultrasound for Acute Phase Examination in Non-Human Primates. 2025 Brain Sci
Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain. 2025 J Biol Chem
Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis. 2025 Proc Natl Acad Sci U S A
The UCSC Genome Browser database: 2025 update. 2025 Nucleic Acids Res
Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction. 2025 Nat Commun
A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-gamma-induced CD38 expression. 2024 Blood
A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis. 2024 Elife
A facilitatory role of astrocytes in axonal regeneration after acute and chronic spinal cord injury. 2024 Exp Neurol
A fibroblast-dependent TGF-beta1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis. 2024 J Clin Invest
A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases. 2024 Nat Commun
A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS. 2024 Nature
A maternal brain hormone that builds bone. 2024 Nature
A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease. 2024 Mol Ther Methods Clin Dev
A Panoramic View of Cell Population Dynamics in Mammalian Aging. 2024 bioRxiv
A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. 2024 Proc Natl Acad Sci U S A
Acid-degradable lipid nanoparticles enhance the delivery of mRNA. 2024 Nat Nanotechnol
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