| Simultaneous multi-site editing of individual genomes using retron arrays. |
2023 |
bioRxiv |
| Single Cell Multimodal Analyses Reveal Epigenomic and Transcriptomic Basis for Birth Defects in Maternal Diabetes. |
2023 |
Nat Cardiovasc Res |
| Single mRNA detection of Wnt signaling pathway in the human limbus. |
2023 |
Exp Eye Res |
| Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. |
2023 |
Sci Adv |
| Single-nuclei transcriptome analysis of Huntington disease iPSC and mouse astrocytes implicates maturation and functional deficits. |
2023 |
iScience |
| SIX1+PAX3+ identify a progenitor for myogenic lineage commitment from hPSCs. |
2023 |
Development |
| Sonogenetic control of multiplexed genome regulation and base editing. |
2023 |
Nat Commun |
| Stable expression of large transgenes via the knock-in of an integrase-deficient lentivirus. |
2023 |
Nat Biomed Eng |
| Stem Cell-Based Organoid Models of Neurodevelopmental Disorders. |
2023 |
Biol Psychiatry |
| Stereochemical Control of Splice Modulation in FD-895 Analogues. |
2023 |
J Med Chem |
| Strength of CAR signaling determines T cell versus ILC differentiation from pluripotent stem cells. |
2023 |
Cell Rep |
| Subfunctionalized expression drives evolutionary retention of ribosomal protein paralogs Rps27 and Rps27l in vertebrates. |
2023 |
Elife |
| Sustained postconfluent culture of human mammary epithelial cells enriches for luminal and c-Kit+ subtypes. |
2023 |
Breast Cancer Res |
| Systems-level analyses dissociate genetic regulators of reactive oxygen species and energy production. |
2023 |
bioRxiv |
| T-allo10 Infusion after αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Improved Immune Reconstitution in the Absence of Severe GvHD |
2023 |
Transplantation and Cellular Therapy |
| Targeted Proteomic Profiling Revealed Roles of Small GTPases during Osteogenic Differentiation. |
2023 |
Anal Chem |
| Targeting the ADPKD methylome using nanoparticle-mediated combination therapy. |
2023 |
APL Bioeng |
| Thalamocortical circuits in generalized epilepsy: Pathophysiologic mechanisms and therapeutic targets. |
2023 |
Neurobiol Dis |
| The sinoatrial node extracellular matrix promotes pacemaker phenotype and protects automaticity in engineered heart tissues from cyclic strain. |
2023 |
Cell Rep |
| Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD(4)-selective WNT surrogate in mice. |
2023 |
Nat Commun |
| Theta Frequency Electromagnetic Stimulation Enhances Functional Recovery After Stroke. |
2023 |
Transl Stroke Res |
| Transcriptional reprogramming restores UBE3A brain-wide and rescues behavioral phenotypes in an Angelman syndrome mouse model. |
2023 |
Mol Ther |
| Transcriptomic Effects on the Mouse Heart Following 30 Days on the International Space Station. |
2023 |
Biomolecules |
| Transplanted human neural stem cells rescue phenotypes in zQ175 Huntington’s disease mice and innervate the striatum. |
2023 |
Mol Ther |
| TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. |
2023 |
Proc Natl Acad Sci U S A |
| Tumor inflammation-associated neurotoxicity. |
2023 |
Nat Med |
| Understanding cell fate acquisition in stem-cell-derived pancreatic islets using single-cell multiome-inferred regulomes. |
2023 |
Dev Cell |
| Understanding Fibroblast Heterogeneity in Form and Function. |
2023 |
Biomedicines |
| Vascularized liver-on-a-chip model to investigate nicotine-induced dysfunction. |
2023 |
Biomicrofluidics |
| Wnt activation as a potential therapeutic approach to treat partial limbal stem cell deficiency. |
2023 |
Sci Rep |
| A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs. |
2022 |
Nat Commun |
| A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. |
2022 |
Muscle Nerve |
| A reference human induced pluripotent stem cell line for large-scale collaborative studies. |
2022 |
Cell Stem Cell |
| A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. |
2022 |
Cell Stem Cell |
| Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice. |
2022 |
Cell Rep |
| Adapting Physiology in Functional Human Islet Organogenesis. |
2022 |
Front Cell Dev Biol |
| Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells. |
2022 |
Front Cell Neurosci |
| Advancing preclinical models of psychiatric disorders with human brain organoid cultures. |
2022 |
Mol Psychiatry |
| Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. |
2022 |
Nat Neurosci |
| An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy. |
2022 |
Cells |
| An NKX-COUP-TFII morphogenetic code directs mucosal endothelial addressin expression. |
2022 |
Nat Commun |
| Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. |
2022 |
Nat Med |
| Antibody screening data of human midgestation liver cells with a focus on hematopoietic, liver sinusoidal endothelial, and hepatoblast cell-populations. |
2022 |
BMC Res Notes |
| Autophagy inducer rapamycin treatment reduces IFN-I-mediated Inflammation and improves anti-HIV-1 T cell response in vivo. |
2022 |
JCI Insight |
| Biallelic pathogenic variants in COX11 are associated with an infantile-onset mitochondrial encephalopathy. |
2022 |
Hum Mutat |
| Biomarkers of in vivo limbal stem cell function. |
2022 |
Ocul Surf |
| Brain organoids, consciousness, ethics and moral status. |
2022 |
Semin Cell Dev Biol |
| c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. |
2022 |
iScience |
| Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. |
2022 |
Cell |
| CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. |
2022 |
Nat Commun |
