Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Organophosphate Flame Retardants, Highly Fluorinated Chemicals, and Biomarkers of Placental Development and Disease During Mid-Gestation. 2021 Toxicol Sci
Overexpression of CD47 is associated with brain overgrowth and 16p11.2 deletion syndrome. 2021 Proc Natl Acad Sci U S A
Patient-derived glial enriched progenitors repair functional deficits due to white matter stroke and vascular dementia in rodents. 2021 Sci Transl Med
peri-Adventitial delivery of smooth muscle cells in porous collagen scaffolds for treatment of experimental abdominal aortic aneurysm. 2021 Biomater Sci
Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids. 2021 EMBO Mol Med
Placental Mesenchymal Stromal Cells: Preclinical Safety Evaluation for Fetal Myelomeningocele Repair. 2021 J Surg Res
Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring. 2021 Science
Proangiogenic Collagen-Binding Glycan Therapeutic Promotes Endothelial Cell Angiogenesis. 2021 ACS Biomater Sci Eng
Regeneration of Jaw Joint Cartilage in Adult Zebrafish. 2021 Front Cell Dev Biol
Regulation of Limbal Epithelial Stem Cells: Importance of the Niche. 2021 Int J Mol Sci
Reliable generation of glial enriched progenitors from human fibroblast-derived iPSCs. 2021 Stem Cell Res
Repeatability of tumor perfusion kinetics from dynamic contrast-enhanced MRI in glioblastoma. 2021 Neurooncol Adv
Retinal Organoids Long-Term Functional Characterization Using Two-Photon Fluorescence Lifetime and Hyperspectral Microscopy. 2021 Front Cell Neurosci
Retinal organoids on-a-chip: a micro-millifluidic bioreactor for long-term organoid maintenance. 2021 Lab Chip
Retinal Protection by Sustained Nanoparticle Delivery of Oncostatin M and Ciliary Neurotrophic Factor Into Rodent Models of Retinal Degeneration. 2021 Transl Vis Sci Technol
Reversing neural circuit and behavior deficit in mice exposed to maternal inflammation by Zika virus. 2021 EMBO Rep
Robust CAR-T memory formation and function via hematopoietic stem cell delivery. 2021 PLoS Pathog
SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery. 2021 Cell Rep
Secretomes of human pluripotent stem cell-derived smooth muscle cell progenitors upregulate extracellular matrix metabolism in the lower urinary tract and vagina. 2021 Stem Cell Res Ther
Selective antisense oligonucleotide inhibition of human IRF4 prevents malignant myeloma regeneration via cell cycle disruption. 2021 Cell Stem Cell
Signaling Pathways That Regulate Normal and Aberrant Red Blood Cell Development. 2021 Genes (Basel)
Skeletal stem and progenitor cells maintain cranial suture patency and prevent craniosynostosis. 2021 Nat Commun
Stem cell-derived CAR T cells traffic to HIV reservoirs in macaques. 2021 JCI Insight
Successful SCID gene therapy in infant with disseminated BCG. 2021 J Allergy Clin Immunol Pract
Superporous agarose scaffolds for encapsulation of adult human islets and human stem-cell-derived beta cells for intravascular bioartificial pancreas applications. 2021 J Biomed Mater Res A
Targeting microRNA-mediated gene repression limits adipogenic conversion of skeletal muscle mesenchymal stromal cells. 2021 Cell Stem Cell
Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis. 2021 Nat Cancer
The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D. 2021 Nature
The developing mouse coronal suture at single-cell resolution. 2021 Nat Commun
The Epithelial-Mesenchymal Transcription Factor SNAI1 Represses Transcription of the Tumor Suppressor miRNA let-7 in Cancer. 2021 Cancers (Basel)
The Rhox gene cluster suppresses germline LINE1 transposition. 2021 Proc Natl Acad Sci U S A
The Unique Properties of Placental Mesenchymal Stromal Cells: A Novel Source of Therapy for Congenital and Acquired Spinal Cord Injury. 2021 Cells
Therapeutic implications of transplanted-cell death. 2021 Nat Biomed Eng
Upregulation of Vitamin C Transporter Functional Expression in 5xFAD Mouse Intestine. 2021 Nutrients
Vitamin C, From Supplement to Treatment: A Re-Emerging Adjunct for Cancer Immunotherapy? 2021 Front Immunol
Wnt signaling activation: targets and therapeutic opportunities for stem cell therapy and regenerative medicine. 2021 RSC Chem Biol
Wnt6 plays a complex role in maintaining human limbal stem/progenitor cells. 2021 Sci Rep
A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids. 2020 Wiley Interdiscip Rev Dev Biol
A Decade of Experience with the Ovine Model of Myelomeningocele: Risk Factors for Fetal Loss. 2020 Fetal Diagn Ther
A Human Skeletal Muscle Atlas Identifies the Trajectories of Stem and Progenitor Cells across Development and from Human Pluripotent Stem Cells. 2020 Cell Stem Cell
A new anabolic compound, LLP2A-Ale, reserves periodontal bone loss in mice through augmentation of bone formation. 2020 BMC Pharmacol Toxicol
A Small-Molecule Wnt Mimic Improves Human Limbal Stem Cell Ex Vivo Expansion. 2020 iScience
Aberrant Development Corrected in Adult-Onset Huntington’s Disease iPSC-Derived Neuronal Cultures via WNT Signaling Modulation. 2020 Stem Cell Reports
Adeno-Associated Virus and Hematopoietic Stem Cells: The Potential of Adeno-Associated Virus Hematopoietic Stem Cells in Genetic Medicines. 2020 Hum Gene Ther
An engineered cell-laden adhesive hydrogel promotes craniofacial bone tissue regeneration in rats. 2020 Sci Transl Med
An intrinsic, label-free signal for identifying stem cell-derived cardiomyocyte subtype. 2020 Stem Cells
Articular cartilage regeneration by activated skeletal stem cells. 2020 Nat Med
Association of polybrominated diphenyl ether (PBDE) levels with biomarkers of placental development and disease during mid-gestation. 2020 Environ Health
Broad-spectrum antibiotics alter the microbiome, increase intestinal fxr, and decrease hepatic steatosis in zebrafish short bowel syndrome. 2020 Am J Physiol Gastrointest Liver Physiol
Busulfan Pharmacokinetics in Adenosine Deaminase-Deficient Severe Combined Immunodeficiency Gene Therapy. 2020 Biol Blood Marrow Transplant