Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Locoregional delivery of IL-13Ralpha2-targeting CAR-T cells in recurrent high-grade glioma: a phase 1 trial. 2024 Nat Med
Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility. 2024 Elife
Mechanistic Understanding of Enhancing Bioactivity via Bio-Ionic Liquids Functionalization of Biomaterials 2024 Applied Materials Today
Microglia are not necessary for maintenance of blood-brain barrier properties in health, but PLX5622 alters brain endothelial cholesterol metabolism. 2024 Neuron
Microglia protect against age-associated brain pathologies. 2024 Neuron
Modeling Cortical Versus Hippocampal Network Dysfunction in a Human Brain Assembloid Model of Epilepsy and Intellectual Disability. 2024 bioRxiv
Molecular profiling of human blastocysts reveals primitive endoderm defects among embryos of decreased implantation potential. 2024 Cell Rep
Multi-lineage heart-chip models drug cardiotoxicity and enhances maturation of human stem cell-derived cardiovascular cells. 2024 Lab Chip
Nanofiber-microwell cell culture system for spatially patterned differentiation of pluripotent stem cells in 3D. 2024 Mater Today Bio
Netrin1 patterns the dorsal spinal cord through modulation of Bmp signaling. 2024 Cell Rep
Neutrophil Granulopoiesis Optimized Through Ex Vivo Expansion of Hematopoietic Progenitors in Engineered 3D Gelatin Methacrylate Hydrogels. 2024 Adv Healthc Mater
Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance. 2024 bioRxiv
Non-canonical Wnt pathway expression in the developing mouse and human retina. 2024 Exp Eye Res
Non-invasive prenatal testing of beta-hemoglobinopathies using next generation sequencing, in-silico sequence size selection, and haplotyping. 2024 Croat Med J
Ocular Mucous Membrane Pemphigoid Demonstrates a Distinct Autoantibody Profile from Those of Other Autoimmune Blistering Diseases: A Preliminary Study. 2024 Antibodies (Basel)
Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy. 2024 Sci Adv
Overexpression of AMPKgamma2 increases AMPK signaling to augment human T cell metabolism and function. 2024 J Biol Chem
Pathway to independence: perspectives on the future. 2024 Development
Perinatal nicotine vaping exposure induces pro-myofibroblastic phenotype in rat bone marrow-derived mesenchymal stem cells. 2024 Reprod Toxicol
Pharmacological inactivation of a non-canonical gp130 signaling arm attenuates chronic systemic inflammation and multimorbidity induced by a high-fat diet. 2024 Sci Rep
Piezo1 regulates meningeal lymphatic vessel drainage and alleviates excessive CSF accumulation. 2024 Nat Neurosci
Precision proteoform design for 4R tau isoform selective templated aggregation. 2024 Proc Natl Acad Sci U S A
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9. 2024 Cell
Recent developments in translational imaging of in vivo gene therapy outcomes. 2024 Mol Ther
Regulation of nuclear transcription by mitochondrial RNA in endothelial cells. 2024 Elife
Respiratory exposure to agricultural dust extract promotes increased intestinal Tnfalpha expression, gut barrier dysfunction, and endotoxemia in mice. 2024 Am J Physiol Gastrointest Liver Physiol
Response to Arbache et al., “Comment on ‘Vulvar lichen sclerosus and vitiligo: Overlap and clinical features'”. 2024 J Am Acad Dermatol
Resuscitative Thoracotomy for Traumatic Cardiac Arrest: Potential Impact of Resource Constraint on Outcomes and Blood Product Utilization. 2024 J Surg Res
Risk Factors for Major Pregnancy Complications in Female Cardiothoracic Surgeons. 2024 Ann Surg
Robust genome and cell engineering via in vitro and in situ circularized RNAs. 2024 Nat Biomed Eng
Role of long noncoding RNAs in diabetes-associated peripheral arterial disease. 2024 Cardiovasc Diabetol
Safeguarding genomic integrity in beta-cells: implications for beta-cell differentiation, growth, and dysfunction. 2024 Biochem Soc Trans
Scaling Insulin-Producing Cells by Multiple Strategies. 2024 Endocrinol Metab (Seoul)
Secondary bone marrow graft loss after third-party virus-specific T cell infusion: Case report of a rare complication. 2024 Nat Commun
Sensory neurons regulate stimulus-dependent humoral immunity in mouse models of bacterial infection and asthma. 2024 Nat Commun
Single Cell Transcriptomics-Informed Induced Pluripotent Stem Cells Differentiation to Tenogenic Lineage. 2024 bioRxiv
Small molecule inhibition of RNA binding proteins in haematologic cancer. 2024 RNA Biol
Stage-specific CAR-mediated signaling generates naive-like, TCR-null CAR T cells from induced pluripotent stem cells. 2024 bioRxiv
Stem cell-derived CAR T cells show greater persistence, trafficking, and viral control compared to ex vivo transduced CAR T cells. 2024 Mol Ther
Surgical pulmonary arterioplasty at bidirectional cavopulmonary anastomosis leads to favorable pulmonary hemodynamics at final stage palliation. 2024 JTCVS Open
Targeting IGF2BP3 enhances antileukemic effects of menin-MLL inhibition in MLL-AF4 leukemia. 2024 Blood Adv
tauFisher predicts circadian time from a single sample of bulk and single-cell pseudobulk transcriptomic data. 2024 Nat Commun
Temporally distinct 3D multi-omic dynamics in the developing human brain. 2024 Nature
The Benefits of Stem Cell Biology and Tissue Engineering in Low-Earth Orbit. 2024 Stem Cells Dev
The cardiac conduction system: History, development, and disease. 2024 Curr Top Dev Biol
The Importance, Challenges, and Possible Solutions for Sharing Proteomics Data While Safeguarding Individuals’ Privacy. 2024 Mol Cell Proteomics
The JAK inhibitor, Tofacitinib, Corrects the Overexpression of CEACAM6 and Limits Susceptibility to AIEC Caused by Reduced Activity of the IBD Associated Gene, PTPN2. 2024 medRxiv
The rise of epitranscriptomics: recent developments and future directions. 2024 Trends Pharmacol Sci
The spatially resolved transcriptome signatures of glomeruli in chronic kidney disease. 2024 JCI Insight
The tardigrade-derived mitochondrial abundant heat soluble protein improves adipose-derived stem cell survival against representative stressors. 2024 Sci Rep