Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes. 2021 Nat Commun
Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis. 2021 Cell
Craniofacial and Long Bone Development in the Context of Distraction Osteogenesis. 2021 Plast Reconstr Surg
CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies. 2021 Cancer Discov
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. 2021 Nat Commun
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma. 2021 J Immunother Cancer
Deep Learning-Assisted Multiphoton Microscopy to Reduce Light Exposure and Expedite Imaging in Tissues With High and Low Light Sensitivity. 2021 Transl Vis Sci Technol
Deficiency of the sedoheptulose kinase (Shpk) does not alter the ability of hematopoietic stem cells to rescue cystinosis in the mouse model. 2021 Mol Genet Metab
Development of selective bispecific Wnt mimetics for bone loss and repair. 2021 Nat Commun
Discordant Virus-Specific Antibody Levels, Antibody Neutralization Capacity, and T-cell Responses Following 3 Doses of SARS-CoV-2 Vaccination in a Patient With Connective Tissue Disease. 2021 Open Forum Infect Dis
Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. 2021 J Med Chem
Distinct skeletal stem cell types orchestrate long bone skeletogenesis. 2021 Elife
Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation. 2021 Hepatology
Early-life inflammation primes a T helper 2 cell-fibroblast niche in skin. 2021 Nature
Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair. 2021 J Pediatr Surg
Enhancing proteasomal processing improves survival for a peptide vaccine used to treat glioblastoma. 2021 Sci Transl Med
Epigenetic silencing directs expression heterogeneity of stably integrated multi-transcript unit genetic circuits. 2021 Sci Rep
Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells. 2021 J Vis Exp
Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation. 2021 Elife
Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function after Chronic Traumatic Brain Injury. 2021 J Neurotrauma
Global proteomic analyses of human cytotrophoblast differentiation/invasion. 2021 Development
Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1. 2021 PLoS One
Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics. 2021 Front Pharmacol
Hematopoietic Stem Cell Gene Therapy for Cystinosis: From Bench-to-Bedside. 2021 Cells
Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis. 2021 Stem Cells
Human limbal epithelial stem cell regulation, bioengineering and function. 2021 Prog Retin Eye Res
Human neural stem cell-derived extracellular vesicles mitigate hallmarks of Alzheimer’s disease. 2021 Alzheimers Res Ther
Identification of neural oscillations and epileptiform changes in human brain organoids. 2021 Nat Neurosci
IFNgamma Is Critical for CAR T Cell-Mediated Myeloid Activation and Induction of Endogenous Immunity. 2021 Cancer Discov
Immune Protection of Stem Cell-Derived Islet Cell Therapy for Treating Diabetes. 2021 Front Endocrinol (Lausanne)
In vitro safety “clinical trial” of the cardiac liability of drug polytherapy. 2021 Clin Transl Sci
Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. 2021 Cell Rep
Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. 2021 Science
Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation device. 2021 Cell Rep Med
Integrated spatial multiomics reveals fibroblast fate during tissue repair. 2021 Proc Natl Acad Sci U S A
Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis. 2021 Nature
Interneuron Dysfunction in a New Mouse Model of SCN1A GEFS. 2021 eNeuro
JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models. 2021 Sci Transl Med
Limbal stem cell diseases. 2021 Exp Eye Res
Long-Term Hypoxia Maintains a State of Dedifferentiation and Enhanced Stemness in Fetal Cardiovascular Progenitor Cells. 2021 Int J Mol Sci
Long-term repair of porcine articular cartilage using cryopreservable, clinically compatible human embryonic stem cell-derived chondrocytes. 2021 NPJ Regen Med
Long-term safety evaluation of placental mesenchymal stromal cells for in utero repair of myelomeningocele in a novel ovine model. 2021 J Pediatr Surg
Long-term SARS-CoV-2-specific immune and inflammatory responses in individuals recovering from COVID-19 with and without post-acute symptoms. 2021 Cell Rep
Making Heads or Tails of the Large Mammalian Sinoatrial Node Micro-Organization. 2021 Circ Arrhythm Electrophysiol
Mesenchymal Stromal Cells Regulate Sialylations of N-Glycans, Affecting Cell Migration and Survival. 2021 Int J Mol Sci
Metallofluorocarbon Nanoemulsion for Inflammatory Macrophage Detection via PET and MRI. 2021 J Nucl Med
Minimizing the risk of occupational Q fever exposure: A protocol for ensuring Coxiella burnetii-negative pregnant ewes are used for medical research. 2021 Lab Anim
Mitochondria as Playmakers of CAR T-cell Fate and Longevity. 2021 Cancer Immunol Res
Modeling preeclampsia using human induced pluripotent stem cells. 2021 Sci Rep