Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
The endogenous progenitor response following traumatic brain injury: a target for cell therapy paradigms. 2022 Neural Regen Res
The G209R mutant mouse as a model for human PCSK1 polyendocrinopathy. 2022 Endocrinology
The Prospects for Retinal Organoids in Treatment of Retinal Diseases. 2022 Asia Pac J Ophthalmol (Phila)
The role of BMP4 signaling in trophoblast emergence from pluripotency. 2022 Cell Mol Life Sci
Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial. 2022 Nat Med
Treatment of a genetic brain disease by CNS-wide microglia replacement. 2022 Sci Transl Med
Understanding Scarring in the Oral Mucosa. 2022 Adv Wound Care (New Rochelle)
Undifferentiated Induced Pluripotent Stem Cells as a Genetic Model for Nonalcoholic Fatty Liver Disease. 2022 Cell Mol Gastroenterol Hepatol
VE-Cadherin: A Critical Sticking Point for Lymphatic System Maintenance: Role of VE-Cadherin in Lymphatic Maintenance. 2022 Circ Res
A bioinspired and chemically defined alternative to dimethyl sulfoxide for the cryopreservation of human hematopoietic stem cells. 2021 Bone Marrow Transplant
A comparative analysis of deferoxamine treatment modalities for dermal radiation-induced fibrosis. 2021 J Cell Mol Med
A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion. 2021 N Engl J Med
A Novel Model of Fetal Spinal Cord Exposure Allowing for Long-Term Postnatal Survival. 2021 Fetal Diagn Ther
Acinar cell clonal expansion in pancreas homeostasis and carcinogenesis. 2021 Nature
Advances in Pancreatic Islet Transplantation Sites for the Treatment of Diabetes. 2021 Front Endocrinol (Lausanne)
Aged skeletal stem cells generate an inflammatory degenerative niche. 2021 Nature
Allogeneic human neural stem cells for improved therapeutic delivery to peritoneal ovarian cancer. 2021 Stem Cell Res Ther
An in vivo Cell-Based Delivery Platform for Zinc Finger Artificial Transcription Factors in Pre-clinical Animal Models. 2021 Front Mol Neurosci
ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. 2021 Cell Stem Cell
Application of lung microphysiological systems to COVID-19 modeling and drug discovery: a review. 2021 Biodes Manuf
Assessing Oximetry Response to Chimeric Antigen Receptor T-cell Therapy against Glioma with (19)F MRI in a Murine Model. 2021 Radiol Imaging Cancer
ATF6 is essential for human cone photoreceptor development. 2021 Proc Natl Acad Sci U S A
Autologous Ex Vivo Lentiviral Gene Therapy for Adenosine Deaminase Deficiency. 2021 N Engl J Med
BAF155 methylation drives metastasis by hijacking super-enhancers and subverting anti-tumor immunity. 2021 Nucleic Acids Res
beta-Globin Lentiviral Vectors Have Reduced Titers due to Incomplete Vector RNA Genomes and Lowered Virion Production. 2021 Stem Cell Reports
Biomaterial-based immunoengineering to fight COVID-19 and infectious diseases. 2021 Matter
Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments. 2021 Biomaterials
Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. 2021 Biofabrication
Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocorticoid receptor activity. 2021 Proc Natl Acad Sci U S A
CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial. 2021 Nat Med
Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations. 2021 Cells
Clearing the Haze: How Does Nicotine Affect Hematopoiesis before and after Birth? 2021 Cancers (Basel)
Clinical outcomes and complications of fluid-filled scleral lens devices for the management of limbal stem cell deficiency. 2021 Cont Lens Anterior Eye
Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats. 2021 Front Neurosci
Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance. 2021 Proc Natl Acad Sci U S A
Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses. 2021 Sci Rep
Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes. 2021 Nat Commun
Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis. 2021 Cell
Craniofacial and Long Bone Development in the Context of Distraction Osteogenesis. 2021 Plast Reconstr Surg
CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies. 2021 Cancer Discov
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. 2021 Nat Commun
Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma. 2021 J Immunother Cancer
Deep Learning-Assisted Multiphoton Microscopy to Reduce Light Exposure and Expedite Imaging in Tissues With High and Low Light Sensitivity. 2021 Transl Vis Sci Technol
Deficiency of the sedoheptulose kinase (Shpk) does not alter the ability of hematopoietic stem cells to rescue cystinosis in the mouse model. 2021 Mol Genet Metab
Development of selective bispecific Wnt mimetics for bone loss and repair. 2021 Nat Commun
Discordant Virus-Specific Antibody Levels, Antibody Neutralization Capacity, and T-cell Responses Following 3 Doses of SARS-CoV-2 Vaccination in a Patient With Connective Tissue Disease. 2021 Open Forum Infect Dis
Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. 2021 J Med Chem
Distinct skeletal stem cell types orchestrate long bone skeletogenesis. 2021 Elife
Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation. 2021 Hepatology
Early-life inflammation primes a T helper 2 cell-fibroblast niche in skin. 2021 Nature