Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
betaDiketonate-Iron(III) Complex: A Versatile Fluorine-19 MRI Signal Enhancement Agent. 2019 ACS Appl Bio Mater
Biological process activity transformation of single cell gene expression for cross-species alignment. 2019 Nat Commun
Biomaterials for tissue repair. 2019 Science
Bortezomib Augments Natural Killer Cell Targeting of Stem-Like Tumor Cells. 2019 Cancers (Basel)
Bovine pericardial extracellular matrix niche modulates human aortic endothelial cell phenotype and function. 2019 Sci Rep
Brain organoids as a model system for human neurodevelopment and disease. 2019 Semin Cell Dev Biol
Brain Organoids as Tools for Modeling Human Neurodevelopmental Disorders. 2019 Physiology (Bethesda)
CaMKII inhibition in human primary and pluripotent stem cell-derived chondrocytes modulates effects of TGFbeta and BMP through SMAD signaling. 2019 Osteoarthritis Cartilage
Cardiac and skeletal muscle effects in the randomized HOPE-Duchenne trial. 2019 Neurology
Cardiac fibrosis: potential therapeutic targets. 2019 Transl Res
CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. 2019 Nature
Chasing Mavericks: The quest for defining developmental waves of hematopoiesis. 2019 Curr Top Dev Biol
Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-beta in iPSC-Derived Alzheimer’s Disease Neurons. 2019 Cell Stem Cell
Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling. 2019 J Clin Invest
Circulating tumor cells exhibit metastatic tropism and reveal brain metastasis drivers. 2019 Cancer Discov
Classification of Limbal Stem Cell Deficiency Using Clinical and Confocal Grading. 2019 Cornea
Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells. 2019 EBioMedicine
Comparison of endothelial keratoplasty techniques in patients with prior glaucoma surgery – a case-matched study. 2019 Am J Ophthalmol
Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. 2019 Cell Stem Cell
CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. 2019 Science
CTCF sites display cell cycle-dependent dynamics in factor binding and nucleosome positioning. 2019 Genome Res
Determining cellular CTCF and cohesin abundances to constrain 3D genome models. 2019 Elife
Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. 2019 J Gen Physiol
Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. 2019 Neuron
Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. 2019 Cell Stem Cell
Development of innate immune cells from human pluripotent stem cells. 2019 Exp Hematol
Diagnostic criteria for limbal stem cell deficiency before surgical intervention-A systematic literature review and analysis. 2019 Surv Ophthalmol
Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. 2019 Cell Stem Cell
Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF. 2019 Mol Cell
Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. 2019 Mol Ther
Effect of inoculum density on human-induced pluripotent stem cell expansion in 3D bioreactors. 2019 Cell Prolif
Effects of Spaceflight and Simulated Microgravity on YAP1 Expression in Cardiovascular Progenitors: Implications for Cell-Based Repair. 2019 Int J Mol Sci
Efficient Differentiation of Human Pluripotent Stem Cells into Liver Cells. 2019 J Vis Exp
Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer. 2019 Mol Ther Oncolytics
Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. 2019 Cell
Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences. 2019 Genes Dev
Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. 2019 Elife
Fiber-based platform for synchronous imaging of endogenous and exogenous fluorescence of biological tissue. 2019 Opt Lett
Fluorous-Soluble Metal Chelate for Sensitive Fluorine-19 Magnetic Resonance Imaging Nanoemulsion Probes. 2019 ACS Nano
Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells. 2019 Methods Mol Biol
Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells. 2019 Nat Med
Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. 2019 Nat Commun
Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts. 2019 Toxicol Sci
Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function. 2019 Cell Rep
Harnessing the versatility of PLGA nanoparticles for targeted Cre-mediated recombination. 2019 Nanomedicine
Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes. 2019 Development
High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia. 2019 Cell Stem Cell
Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. 2019 Cell Stem Cell
Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility. 2019 Nat Commun
Human induced pluripotent stem cell line with genetically encoded fluorescent voltage indicator generated via CRISPR for action potential assessment post-cardiogenesis. 2019 Stem Cells