| Biophysical matrix cues from the regenerating niche direct muscle stem cell fate in engineered microenvironments. |
2021 |
Biomaterials |
| Bioprinting of dual ECM scaffolds encapsulating limbal stem/progenitor cells in active and quiescent statuses. |
2021 |
Biofabrication |
| Bromodomain containing 9 (BRD9) regulates macrophage inflammatory responses by potentiating glucocorticoid receptor activity. |
2021 |
Proc Natl Acad Sci U S A |
| CAR T cells with dual targeting of CD19 and CD22 in adult patients with recurrent or refractory B cell malignancies: a phase 1 trial. |
2021 |
Nat Med |
| Characterization and Biomarker Analyses of Post-COVID-19 Complications and Neurological Manifestations. |
2021 |
Cells |
| Clearing the Haze: How Does Nicotine Affect Hematopoiesis before and after Birth? |
2021 |
Cancers (Basel) |
| Clinical outcomes and complications of fluid-filled scleral lens devices for the management of limbal stem cell deficiency. |
2021 |
Cont Lens Anterior Eye |
| Co-grafts of Human Embryonic Stem Cell Derived Retina Organoids and Retinal Pigment Epithelium for Retinal Reconstruction in Immunodeficient Retinal Degenerate Royal College of Surgeons Rats. |
2021 |
Front Neurosci |
| Combining CD47 blockade with trastuzumab eliminates HER2-positive breast cancer cells and overcomes trastuzumab tolerance. |
2021 |
Proc Natl Acad Sci U S A |
| Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses. |
2021 |
Sci Rep |
| Conservation and divergence of vulnerability and responses to stressors between human and mouse astrocytes. |
2021 |
Nat Commun |
| Cranial Suture Regeneration Mitigates Skull and Neurocognitive Defects in Craniosynostosis. |
2021 |
Cell |
| Craniofacial and Long Bone Development in the Context of Distraction Osteogenesis. |
2021 |
Plast Reconstr Surg |
| CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies. |
2021 |
Cancer Discov |
| Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses. |
2021 |
Nat Commun |
| Deep immune profiling reveals targetable mechanisms of immune evasion in immune checkpoint inhibitor-refractory glioblastoma. |
2021 |
J Immunother Cancer |
| Deep Learning-Assisted Multiphoton Microscopy to Reduce Light Exposure and Expedite Imaging in Tissues With High and Low Light Sensitivity. |
2021 |
Transl Vis Sci Technol |
| Deficiency of the sedoheptulose kinase (Shpk) does not alter the ability of hematopoietic stem cells to rescue cystinosis in the mouse model. |
2021 |
Mol Genet Metab |
| Development of allogeneic HSC-engineered iNKT cells for off-the-shelf cancer immunotherapy. |
2021 |
Cell Rep Med |
| Development of selective bispecific Wnt mimetics for bone loss and repair. |
2021 |
Nat Commun |
| Development of Stem Cell-Derived Immune Cells for Off-the-Shelf Cancer Immunotherapies. |
2021 |
Cells |
| Discordant Virus-Specific Antibody Levels, Antibody Neutralization Capacity, and T-cell Responses Following 3 Doses of SARS-CoV-2 Vaccination in a Patient With Connective Tissue Disease. |
2021 |
Open Forum Infect Dis |
| Discovery and Mechanism of SARS-CoV-2 Main Protease Inhibitors. |
2021 |
J Med Chem |
| Distinct skeletal stem cell types orchestrate long bone skeletogenesis. |
2021 |
Elife |
| Doxycycline Significantly Enhances Induction of Induced Pluripotent Stem Cells to Endoderm by Enhancing Survival Through Protein Kinase B Phosphorylation. |
2021 |
Hepatology |
| Early-life inflammation primes a T helper 2 cell-fibroblast niche in skin. |
2021 |
Nature |
| Efficacy of clinical-grade human placental mesenchymal stromal cells in fetal ovine myelomeningocele repair. |
2021 |
J Pediatr Surg |
| Engineering stem cells for cancer immunotherapy. |
2021 |
Trends Cancer |
| Enhancing proteasomal processing improves survival for a peptide vaccine used to treat glioblastoma. |
2021 |
Sci Transl Med |
| Epigenetic silencing directs expression heterogeneity of stably integrated multi-transcript unit genetic circuits. |
2021 |
Sci Rep |
| Fabrication of 3D Cardiac Microtissue Arrays using Human iPSC-Derived Cardiomyocytes, Cardiac Fibroblasts, and Endothelial Cells. |
2021 |
J Vis Exp |
| Foxc1 establishes enhancer accessibility for craniofacial cartilage differentiation. |
2021 |
Elife |
| Freshly Thawed Cryobanked Human Neural Stem Cells Engraft within Endogenous Neurogenic Niches and Restore Cognitive Function after Chronic Traumatic Brain Injury. |
2021 |
J Neurotrauma |
| Global proteomic analyses of human cytotrophoblast differentiation/invasion. |
2021 |
Development |
| Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1. |
2021 |
PLoS One |
| Heart Muscle Microphysiological System for Cardiac Liability Prediction of Repurposed COVID-19 Therapeutics. |
2021 |
Front Pharmacol |
| Hematopoietic Stem Cell Gene Therapy for Cystinosis: From Bench-to-Bedside. |
2021 |
Cells |
| Human induced pluripotent stem cell-derived macrophages ameliorate liver fibrosis. |
2021 |
Stem Cells |
| Human limbal epithelial stem cell regulation, bioengineering and function. |
2021 |
Prog Retin Eye Res |
| Human neural stem cell-derived extracellular vesicles mitigate hallmarks of Alzheimer’s disease. |
2021 |
Alzheimers Res Ther |
| Identification of neural oscillations and epileptiform changes in human brain organoids. |
2021 |
Nat Neurosci |
| IFNgamma Is Critical for CAR T Cell-Mediated Myeloid Activation and Induction of Endogenous Immunity. |
2021 |
Cancer Discov |
| Immune Protection of Stem Cell-Derived Islet Cell Therapy for Treating Diabetes. |
2021 |
Front Endocrinol (Lausanne) |
| In vitro safety “clinical trial” of the cardiac liability of drug polytherapy. |
2021 |
Clin Transl Sci |
| Inflammation-driven deaminase deregulation fuels human pre-leukemia stem cell evolution. |
2021 |
Cell Rep |
| Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength. |
2021 |
Science |
| Insulin expression and C-peptide in type 1 diabetes subjects implanted with stem cell-derived pancreatic endoderm cells in an encapsulation device. |
2021 |
Cell Rep Med |
| Integrated spatial multiomics reveals fibroblast fate during tissue repair. |
2021 |
Proc Natl Acad Sci U S A |
| Inter-cellular CRISPR screens reveal regulators of cancer cell phagocytosis. |
2021 |
Nature |
| Interneuron Dysfunction in a New Mouse Model of SCN1A GEFS. |
2021 |
eNeuro |
