City of Hope, Beckman Research Institute

Total Awards: 
50
Award Value: 
$165,129,132
Institution type: 
Not for profit
Short Name: 
COH

Awards to the Institution

Program Investigator Award Title Award Value
SEED Grant Timothy O'Connor Sources of Genetic Instability in Human Embryonic Stem Cells. $327,311
Disease Team Planning Michael Barish Genetically-modified neural stem cells for treatment of high-grade glioma $55,000
Conference Fouad Kandeel 2013 Rachmiel Diabetes and Obesity Levine Symposium - Advances in Diabetes Research $27,750
Conference - The 2017 Alpha Stem Cell Clinic Annual Symposium John Zaia 2nd Annual Symposium of the CIRM Alpha Stem Cell Clinics Network "Alpha Clinics - Making the Future a Reality for Stem Cell-Based Therapies" $79,287
Late Stage Preclinical Projects Xiuli Wang CMV-specific T cells expressing anti-HIV CAR and CMV vaccine boost as immunotherapy for HIV/AIDS $3,812,797
SPARK David Ann Train, Educate, and Accelerate Mastery of Stem cell research (TEAMS) program $508,750
Tools and Technologies I Larry Couture Development of Suspension Adaptation, Scale-up cGMP Banking and Cell Characterization Technologies for hESC Lines $882,929
Strategic Partnership III Track A John Zaia A Phase I, Open-Label Study To Assess The Safety, Feasibility and Engraftment of Zinc Finger Nucleases (ZFN) CCR5 Modified Autologous CD34+ Hematopoietic Stem/Progenitor Cells (SB-728MR-HSPC) with Escalating Doses of Busulfan In HIV-1 (R5) Infected Sub... $5,583,438
Conference Fouad Kandeel 2011 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Research $15,000
Quest - Discovery Stage Research Projects Markus Müschen Lgr5-mediated self-renewal in B cell selection and leukemia-initiation $2,186,520
Clinical Trial Stage Projects Saul Priceman A Phase I Study of Chimeric Antigen Receptor Engineered Stem/Memory T Cells for the Treatment of HER2-Positive Brain Metastases $9,015,149
Clinical Trial Stage Projects Jana Portnow A Phase I Study of Multiple doses of NSC-Based Oncolytic Virotherapy Administered Intracerebrally to Patients with Recurrent High-Grade Gliomas $11,999,984
New Faculty I Tiziano Barberi Skeletal muscle development from hESC and its in vivo applications in animal models of muscular dystrophy $131,840
Alpha Stem Cell Clinics John Zaia The Innovation-Alpha Clinic for Cellular Therapies (I-ACT) – A Program for the Development and Delivery of Innovative Cell-based Treatments and Cures for Life-threatening Diseases. $8,456,000
Conference Fouad Kandeel 2012 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Research $15,000
Quest - Discovery Stage Research Projects Yuan Chen A Novel Approach to Eradicate Cancer Stem Cells $1,539,935
Therapeutic Translational Research Projects Karen Aboody Neural Stem cell-mediated oncolytic immunotherapy for ovarian cancer $2,873,262
Alpha Stem Cell Clinics Network Expansion Leo Wang The City of Hope Alpha Clinic: A roadmap for equitable and inclusive access to regenerative medicine therapies for all Californians $8,000,000
Basic Biology III Jiing-Kuan Yee Use of human iPS cells to study spinal muscular atrophy $1,268,868
Tools and Technologies III Joseph Gold Development of a scalable, practical, and transferable GMP-compliant suspension culture-based differentiation process for cardiomyocyte production from human embryonic stem cells. $891,518
Conference Richard Jove New Approaches in Cell Based Therapies $20,000
Clinical Trial Stage Projects Christine Brown Phase I Study of Chimeric Antigen Receptor Engineered Central Memory T cells for the Treatment of Malignant Glioma $12,753,854
Clinical Trial Stage Projects John Zaia Evaluation and Characterization of SARS-CoV-2 Antibody in Convalescent Volunteer Plasma Donors for Potential Therapeutic Use $999,999
Therapeutic Translational Research Projects Jianhua Yu Specific Targeting Hypoxia Metastatic Breast Tumor with Allogeneic Off-the-Shelf Anti-EGFR CAR NK Cells Expressing an ODD domain of HIF-1α $6,036,002
Early Translational II Yanhong Shi Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
Research Training II Michael Barish City of Hope Research Training Program in Stem Cell Biology $2,197,782
SPARK Paul Salvaterra SPARK Award Program in Stem Cell Biology for California High School Students $241,080
Conference Richard Jove Innovation and Translational Stem Cell Therapy for Diabetes and Neurological Diseases: Paving the way for real life solutions $14,878
Quest - Discovery Stage Research Projects Saswati Chatterjee Genome Editing of Sinusoidal Endothelial Stem Cells for Permanent Correction of Hemophilia A $2,182,193
Discovery Research Projects Jianhua Yu Persistent Off-the-Shelf meACE2-CAR-IL-15 NK Cells Derived from CD34(+) Cord Blood Stem Cells to Prevent and Treat COVID-19 $150,000
Quest - Discovery Stage Research Projects Jianhua Yu Reprogramming Somatic Cells into iPSCs Engineered with an Anti-PSCA CAR to Develop Allogeneic Off-the-Shelf Cell Therapy to Treat Pancreatic Cancer $2,263,500
Early Translational II David DiGiusto Development of RNA-based approaches to stem cell gene therapy for HIV $3,097,160
Early Translational III Stephen Forman Targeting glioma cancer stem cells with receptor-engineered self-renewing memory T cells $5,215,447
Therapeutic Translational Research Projects Yanhong Shi Process development for establishing an iPSC-based therapeutic candidate for Canavan disease $7,377,384
Conference Richard Jove Innovative Partnerships: Bringing Stem Cell Discoveries to the Clinic $14,994
Clinical Trial Stage Projects De-Fu Zeng Treatment of sickle cell disease by induction of mixed chimerism and immune tolerance using CD4+ T-depleted haploidentical blood stem cell transplant $4,352,180
Quest - Discovery Stage Research Projects Yanhong Shi Combating COVID-19 using human PSC-derived NK cells $249,998
Therapeutic Translational Research Projects Michael Caligiuri Targeting multiple myeloma with BCMA-CAR NK cells expressing a GPRC5D-NKG2D bispecific antibody $6,036,001
Disease Team Research I Karen Aboody Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials $17,890,623
Basic Biology IV Yanhong Shi Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,366,656
Conference II Fouad Kandeel 2016 Rachmiel Levine-Arthur Riggs Diabetes Research Symposium $10,000
Conference Fouad Kandeel 15th Annual Rachmiel Levine Diabetes and Obesity Symposium $20,000
Late Stage Preclinical Projects John Zaia Ex Vivo Gene Engineering of Blood Stem Cells for Enhanced Chemotherapy Efficacy in Glioblastoma Patients $3,684,259
Clinical Trial Stage Projects Leo Wang Phase I Study of IL13Rα2-Targeting CAR T Cells After Lymphodepletion for Children with Refractory or Recurrent Malignant Brain Tumors $8,401,309
Disease Team Research I John Zaia ZINC FINGER NUCLEASE-BASED STEM CELL THERAPY FOR AIDS $14,536,969
Creativity Awards Paul Salvaterra Creativity Award Program in Stem Cell Biology for California High School Students $260,825
Conference Fouad Kandeel 2009 Rachmiel Levine Diabetes and Obesity Symposium: Advances in Diabetes Biology, Immunology and Cell Therapy $15,000
Conference - Manage The SPARK Annual Meeting Paul Salvaterra Manage the 2017 SPARK Annual Meeting $22,555
Quest - Discovery Stage Research Projects Saul Priceman Chimeric Antigen Receptor-Engineered Stem/Memory T Cells for the Treatment of Recurrent Ovarian Cancer $1,351,174
Research Training Grant Michael Barish Research Training Program in Stem Cell Biology and Regenerative Medicine $4,860,989
Total:
$165,129,132.00
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