CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.
Check out our portfolio of awards below. Click here to see a list of People We’ve Funded. Click here to see a list of our Funded Institutions.
All CIRM Grants
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| Institution |
Researcher name |
Grant Type |
Grant Title |
Award Value |
| University of California, Berkeley |
Kevin E. Healy |
Quest – Discovery Stage Research Projects |
Human Cardiac Chip for Assessment of Proarrhythmic Risk |
$899,581 |
| University of California, San Francisco |
Dr. Holger F Willenbring |
Quest – Discovery Stage Research Projects |
Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis |
$1,638,389 |
| Scaled Biolabs Inc. |
Dr Justin Cooper-White |
Quest – Discovery Stage Research Projects |
A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs |
$657,528 |
| City of Hope, Beckman Research Institute |
Markus Müschen |
Quest – Discovery Stage Research Projects |
Lgr5-mediated self-renewal in B cell selection and leukemia-initiation |
$2,183,223 |
| University of California, San Diego |
Professor Alysson R Muotri |
Quest – Discovery Stage Research Projects |
A treatment for Zika virus infection and neuroprotection efficacy |
$1,924,524 |
| Stanford University |
Dr. Matthew H Porteus |
Quest – Discovery Stage Research Projects |
Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells |
$1,968,456 |
| University of California, San Francisco |
Dr. Julie B Sneddon |
Quest – Discovery Stage Research Projects |
Designing a cellular niche for transplantation of human embryonic stem cell-derived beta cells |
$2,006,076 |
| University of California, Los Angeles |
Dr. John P Chute |
Quest – Discovery Stage Research Projects |
Protein tyrosine phosphatase – sigma inhibitors for hematopoietic regeneration |
$2,115,735 |
| University of California, San Diego |
Dan S Kaufman |
Quest – Discovery Stage Research Projects |
Targeted off-the-shelf immunotherapy to treat refractory cancers |
$1,936,936 |
| Parkinson’s Institute |
Dr. Birgitt Schuele |
Quest – Discovery Stage Research Projects |
CRISPR/dCas9 mutant targeting SNCA promoter for downregulation of alpha-synuclein expression as a novel therapeutic approach for Parkinson’s disease |
$1,288,415 |
| Gladstone Institutes, J. David |
Dr. Deepak Srivastava |
Quest – Discovery Stage Research Projects |
Direct Cardiac Reprogramming for Regenerative Medicine |
$2,392,157 |
| University of California, Irvine |
Dr. Leslie M Thompson |
Quest – Discovery Stage Research Projects |
hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease |
$1,650,263 |
| Stanford University |
Dr. Roel Nusse |
Quest – Discovery Stage Research Projects |
Preclinical development of human hepatocyte progenitor cells for cell therapy |
$1,651,211 |
| University of California, San Francisco |
Dr. Tejal Ashwin Desai |
Quest – Discovery Stage Research Projects |
Thin Film Encapsulation Devices for Human Stem Cell derived Insulin Producing Cells |
$1,092,063 |
| Stanford University |
Dr. Rosa Bacchetta |
Quest – Discovery Stage Research Projects |
GENE EDITING FOR FOXP3 IN HUMAN HSC |
$984,228 |
| California Institute of Technology |
Dr. David Baltimore PhD |
Quest – Discovery Stage Research Projects |
Immunotherapy for HIV infection using engineered hematopoietic stem/progenitor cells |
$1,569,193 |
| Gladstone Institutes, J. David |
Dr. Deepak Srivastava |
Quest – Discovery Stage Research Projects |
Use of Human iPSC-derived Endothelial Cells for Calcific Aortic Valve Disease Therapeutics |
$2,400,048 |
| Scripps Research Institute |
Dr. Jeanne F Loring |
Quest – Discovery Stage Research Projects |
Autologous cell therapy for Parkinson’s disease using iPSC-derived DA neurons |
$2,299,786 |
| University of California, Davis |
Dr. David J Segal PhD |
Quest – Discovery Stage Research Projects |
MSC delivery of an artificial transcription factor to the brain as a treatment for Angelman Syndrome |
$1,055,319 |
| University of California, Berkeley |
John Dueber |
Quest – Discovery Stage Research Projects |
Scalable, Defined Production of Oligodendrocyte Precursor Cells to Treat Neural Disease and Injury |
$1,627,099 |
| Stanford University |
Professor Hiromitsu Nakauchi |
Quest – Discovery Stage Research Projects |
Novel Rejuvenated T Cell Immunotherapy for Lung Cancer |
$1,968,456 |
| University of California, Los Angeles |
Dr. April Pyle Ph.D. |
Quest – Discovery Stage Research Projects |
CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells |
$2,150,400 |
| Stanford University |
Dr. Katja Weinacht |
Preclinical Stage Projects |
Therapeutic Restoration of Immune Function through iPSC-derived Human Thymic Epithelial Cells |
$12,999,871 |
| EVADE Therapeutics |
Sonja Schrepfer |
Preclinical Stage Projects |
Hypoimmune Stem Cell–Derived Islets: A Next-Generation Cell Therapy Toward a Functional Cure for Type 1 Diabetes |
$12,480,000 |
| University of Southern California |
Charles Murry |
Preclinical Stage Projects |
Regenerating the Acutely Infarcted Heart with iPSC-Ventricular Cardiomyocytes. |
$7,499,998 |
| University of California, Los Angeles |
Dr. Lili Yang |
Preclinical Stage Projects |
Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy for Multiple Sclerosis |
$7,499,996 |
| Scribe Therapeutics |
Brett Staahl |
Preclinical Stage Projects |
A First-in-Class CIRSPR-CasX Gene Editing Therapy for Lowering Lp(a) to Prevent
Cardiovascular Events |
$12,714,480 |
| 4D Molecular Therapeutics, Inc. |
Sara Collins |
Preclinical Stage Projects |
Gene Therapy for Alpha-1 Anti-Trypsin Deficiency |
$5,915,073 |
| AcuraStem Incorporated |
Mr. Samuel V. Alworth MS, MBA |
Preclinical Stage Projects |
Late-stage development of AS-241, an UNC13A Targeting Antisense Oligonucleotide treatment for Amyotrophic Lateral Sclerosis, for IND-enabling studies |
$7,500,000 |
| Cure Rare Disease |
Dr. Tahseen Mozaffar |
Preclinical Stage Projects |
Advancement of a myotropic, liver-detargeting therapy for LGMD2i/R9 |
$7,292,297 |
| Scribe Therapeutics |
Brett Staahl |
Preclinical Stage Projects |
A first-in-class CRISPR-CasX gene editor silencing APOC3 transcription for the treatment of Severe Hypertriglyceridemia |
$13,000,000 |
| Savanna Biotherapeutics, Inc. |
Dr. Sunil Gandhi Ph.D |
Preclinical Stage Projects |
Microglia replacement therapy for CSF1R-related Leukoencephalopathy |
$12,993,456 |
| Cedars-Sinai Medical Center |
Dr. David Joseph Lefer |
Preclinical Stage Projects |
TY1 and Semaglutide to Treat Cardiometabolic HFpEF |
$10,571,220 |
| University of California, San Diego |
Dr. Stephanie Cherqui |
Preclinical Stage Projects |
CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia |
$7,423,504 |
| Cedars-Sinai Medical Center |
Dr. Alessandra Ciullo |
Preclinical Stage Projects |
Noncoding RNA drug TY2 for arrhythmogenic cardiomyopathy |
$10,419,929 |
| Navega Therapeutics |
Ana Maria Moreno |
Preclinical Stage Projects |
Development of an AAV Epigenetic Gene Therapy for Intractable Chronic Pain Disorders |
$9,486,864 |
| Scripps Health |
Dr. Darryl D. D’Lima |
Preclinical Stage Projects |
Stem Cell-Based Cartilage Tissue Regeneration |
$12,715,000 |
| Stanford University |
Dr. Bertha Chen |
Preclinical Stage Projects |
Autologous iPSC-derived progenitor smooth muscle cells for treatment of urinary incontinence |
$7,275,596 |
| Loma Linda University |
Hisham Abdel-Azim |
CCCE Grant |
Inland Empire and Desert Region CIRM Community Care Center of Excellence |
$9,000,000 |
| Fresno Community Hospital and Medical Center |
Haifaa Abdulhaq |
CCCE Grant |
Establishing a CIRM Community Care Center of Excellence in the Central Valley |
$8,996,101 |
| Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center |
Lynda Polgreen MD |
CCCE Grant |
South Los Angeles Community Center of Excellence for Regenerative Medicine |
$9,000,000 |
| Stanford University |
Dr. Michael P Snyder PhD |
ReMIND – Discovery Stage ReMIND |
Dissecting cell-specific genetic and molecular drivers of amyotrophic lateral sclerosis for therapeutic insights |
$12,999,837 |
| Stanford University |
Sergiu P Pasca |
ReMIND – Discovery Stage ReMIND |
Transplantation of human forebrain assembloids as a platform for therapeutic screening in neurodevelopmental disorders |
$13,999,999 |
| University of California, Los Angeles |
Daniel Geschwind |
ReMIND – Discovery Stage ReMIND |
Advancing Therapeutic Discovery Through Multimodal Analyses of Genetic and Cellular Mechanisms in Neuropsychiatric Disorders |
$13,957,175 |
| University of California, San Diego |
Dr. Gene Wei-Ming Yeo |
ReMIND – Discovery Stage ReMIND |
Reversing age-dependent neurodegeneration by elimination of RNA pollution |
$13,000,000 |
| Salk Institute for Biological Studies |
Christian Metallo |
ReMIND – Discovery Stage ReMIND |
Tracing the metabolic basis of neurological disorders |
$12,995,613 |
| University of California, San Francisco |
Dr. Arnold Kriegstein |
ReMIND – Discovery Stage ReMIND |
Defining the Developmental Origins and Neuronal Regulation of Glioblastoma Stem Cells |
$13,578,858 |
| University of California, San Diego |
Jonathan Sebat |
ReMIND – Discovery Stage ReMIND |
Modeling the genetic basis of psychopathology in schizophrenia and autism |
$12,703,708 |
| University of California, San Francisco |
Mercedes Paredes |
ReMIND – Discovery Stage ReMIND |
Multi-gene modulation to rescue CNS-associated microdeletion syndromes |
$6,253,897 |
| University of California, Los Angeles |
Aparna Bhaduri |
ReMIND – Discovery Stage ReMIND |
Defining Neurovascular Metabolism in Neurodevelopmental and Neuropsychiatric Disorders |
$10,330,000 |