Our Grants

CIRM provides funding across five key areas: Infrastructure, Education, Discovery Research, Translational Research, and Clinical Research. By supporting projects at every stage of development, from initial discovery to clinical trials, CIRM drives progress in regenerative medicine and accelerates innovative therapies to patients.

Check out our portfolio of awards below. Click here to see a list of People We’ve Funded. Click here to see a list of our Funded Institutions.

All CIRM Grants

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Institution Researcher name Grant Type Grant Title Award Value
University of California, Berkeley Kevin E. Healy Quest – Discovery Stage Research Projects Human Cardiac Chip for Assessment of Proarrhythmic Risk $899,581
University of California, San Francisco Dr. Holger F Willenbring Quest – Discovery Stage Research Projects Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis $1,638,389
Scaled Biolabs Inc. Dr Justin Cooper-White Quest – Discovery Stage Research Projects A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs $657,528
City of Hope, Beckman Research Institute Markus Müschen Quest – Discovery Stage Research Projects Lgr5-mediated self-renewal in B cell selection and leukemia-initiation $2,183,223
University of California, San Diego Professor Alysson R Muotri Quest – Discovery Stage Research Projects A treatment for Zika virus infection and neuroprotection efficacy $1,924,524
Stanford University Dr. Matthew H Porteus Quest – Discovery Stage Research Projects Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells $1,968,456
University of California, San Francisco Dr. Julie B Sneddon Quest – Discovery Stage Research Projects Designing a cellular niche for transplantation of human embryonic stem cell-derived beta cells $2,006,076
University of California, Los Angeles Dr. John P Chute Quest – Discovery Stage Research Projects Protein tyrosine phosphatase – sigma inhibitors for hematopoietic regeneration $2,115,735
University of California, San Diego Dan S Kaufman Quest – Discovery Stage Research Projects Targeted off-the-shelf immunotherapy to treat refractory cancers $1,936,936
Parkinson’s Institute Dr. Birgitt Schuele Quest – Discovery Stage Research Projects CRISPR/dCas9 mutant targeting SNCA promoter for downregulation of alpha-synuclein expression as a novel therapeutic approach for Parkinson’s disease $1,288,415
Gladstone Institutes, J. David Dr. Deepak Srivastava Quest – Discovery Stage Research Projects Direct Cardiac Reprogramming for Regenerative Medicine $2,392,157
University of California, Irvine Dr. Leslie M Thompson Quest – Discovery Stage Research Projects hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease $1,650,263
Stanford University Dr. Roel Nusse Quest – Discovery Stage Research Projects Preclinical development of human hepatocyte progenitor cells for cell therapy $1,651,211
University of California, San Francisco Dr. Tejal Ashwin Desai Quest – Discovery Stage Research Projects Thin Film Encapsulation Devices for Human Stem Cell derived Insulin Producing Cells $1,092,063
Stanford University Dr. Rosa Bacchetta Quest – Discovery Stage Research Projects GENE EDITING FOR FOXP3 IN HUMAN HSC $984,228
California Institute of Technology Dr. David Baltimore PhD Quest – Discovery Stage Research Projects Immunotherapy for HIV infection using engineered hematopoietic stem/progenitor cells $1,569,193
Gladstone Institutes, J. David Dr. Deepak Srivastava Quest – Discovery Stage Research Projects Use of Human iPSC-derived Endothelial Cells for Calcific Aortic Valve Disease Therapeutics $2,400,048
Scripps Research Institute Dr. Jeanne F Loring Quest – Discovery Stage Research Projects Autologous cell therapy for Parkinson’s disease using iPSC-derived DA neurons $2,299,786
University of California, Davis Dr. David J Segal PhD Quest – Discovery Stage Research Projects MSC delivery of an artificial transcription factor to the brain as a treatment for Angelman Syndrome $1,055,319
University of California, Berkeley John Dueber Quest – Discovery Stage Research Projects Scalable, Defined Production of Oligodendrocyte Precursor Cells to Treat Neural Disease and Injury $1,627,099
Stanford University Professor Hiromitsu Nakauchi Quest – Discovery Stage Research Projects Novel Rejuvenated T Cell Immunotherapy for Lung Cancer $1,968,456
University of California, Los Angeles Dr. April Pyle Ph.D. Quest – Discovery Stage Research Projects CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells $2,150,400
Stanford University Dr. Katja Weinacht Preclinical Stage Projects Therapeutic Restoration of Immune Function through iPSC-derived Human Thymic Epithelial Cells $12,999,871
EVADE Therapeutics Sonja Schrepfer Preclinical Stage Projects Hypoimmune Stem Cell–Derived Islets: A Next-Generation Cell Therapy Toward a Functional Cure for Type 1 Diabetes $12,480,000
University of Southern California Charles Murry Preclinical Stage Projects Regenerating the Acutely Infarcted Heart with iPSC-Ventricular Cardiomyocytes. $7,499,998
University of California, Los Angeles Dr. Lili Yang Preclinical Stage Projects Stem Cell-Engineered Off-The-Shelf CAR-NKT Cell Therapy for Multiple Sclerosis $7,499,996
Scribe Therapeutics Brett Staahl Preclinical Stage Projects A First-in-Class CIRSPR-CasX Gene Editing Therapy for Lowering Lp(a) to Prevent Cardiovascular Events $12,714,480
4D Molecular Therapeutics, Inc. Sara Collins Preclinical Stage Projects Gene Therapy for Alpha-1 Anti-Trypsin Deficiency $5,915,073
AcuraStem Incorporated Mr. Samuel V. Alworth MS, MBA Preclinical Stage Projects Late-stage development of AS-241, an UNC13A Targeting Antisense Oligonucleotide treatment for Amyotrophic Lateral Sclerosis, for IND-enabling studies $7,500,000
Cure Rare Disease Dr. Tahseen Mozaffar Preclinical Stage Projects Advancement of a myotropic, liver-detargeting therapy for LGMD2i/R9 $7,292,297
Scribe Therapeutics Brett Staahl Preclinical Stage Projects A first-in-class CRISPR-CasX gene editor silencing APOC3 transcription for the treatment of Severe Hypertriglyceridemia $13,000,000
Savanna Biotherapeutics, Inc. Dr. Sunil Gandhi Ph.D Preclinical Stage Projects Microglia replacement therapy for CSF1R-related Leukoencephalopathy $12,993,456
Cedars-Sinai Medical Center Dr. David Joseph Lefer Preclinical Stage Projects TY1 and Semaglutide to Treat Cardiometabolic HFpEF $10,571,220
University of California, San Diego Dr. Stephanie Cherqui Preclinical Stage Projects CRISPR/Cas9-mediated gene editing of Hematopoietic stem and progenitor cells for Friedreich’s ataxia $7,423,504
Cedars-Sinai Medical Center Dr. Alessandra Ciullo Preclinical Stage Projects Noncoding RNA drug TY2 for arrhythmogenic cardiomyopathy $10,419,929
Navega Therapeutics Ana Maria Moreno Preclinical Stage Projects Development of an AAV Epigenetic Gene Therapy for Intractable Chronic Pain Disorders $9,486,864
Scripps Health Dr. Darryl D. D’Lima Preclinical Stage Projects Stem Cell-Based Cartilage Tissue Regeneration $12,715,000
Stanford University Dr. Bertha Chen Preclinical Stage Projects Autologous iPSC-derived progenitor smooth muscle cells for treatment of urinary incontinence $7,275,596
Loma Linda University Hisham Abdel-Azim CCCE Grant Inland Empire and Desert Region CIRM Community Care Center of Excellence $9,000,000
Fresno Community Hospital and Medical Center Haifaa Abdulhaq CCCE Grant Establishing a CIRM Community Care Center of Excellence in the Central Valley $8,996,101
Lundquist Institute for Biomedical Innovation at Harbor – UCLA Medical Center Lynda Polgreen MD CCCE Grant South Los Angeles Community Center of Excellence for Regenerative Medicine $9,000,000
Stanford University Dr. Michael P Snyder PhD ReMIND – Discovery Stage ReMIND Dissecting cell-specific genetic and molecular drivers of amyotrophic lateral sclerosis for therapeutic insights $12,999,837
Stanford University Sergiu P Pasca ReMIND – Discovery Stage ReMIND Transplantation of human forebrain assembloids as a platform for therapeutic screening in neurodevelopmental disorders $13,999,999
University of California, Los Angeles Daniel Geschwind ReMIND – Discovery Stage ReMIND Advancing Therapeutic Discovery Through Multimodal Analyses of Genetic and Cellular Mechanisms in Neuropsychiatric Disorders $13,957,175
University of California, San Diego Dr. Gene Wei-Ming Yeo ReMIND – Discovery Stage ReMIND Reversing age-dependent neurodegeneration by elimination of RNA pollution $13,000,000
Salk Institute for Biological Studies Christian Metallo ReMIND – Discovery Stage ReMIND Tracing the metabolic basis of neurological disorders $12,995,613
University of California, San Francisco Dr. Arnold Kriegstein ReMIND – Discovery Stage ReMIND Defining the Developmental Origins and Neuronal Regulation of Glioblastoma Stem Cells $13,578,858
University of California, San Diego Jonathan Sebat ReMIND – Discovery Stage ReMIND Modeling the genetic basis of psychopathology in schizophrenia and autism $12,703,708
University of California, San Francisco Mercedes Paredes ReMIND – Discovery Stage ReMIND Multi-gene modulation to rescue CNS-associated microdeletion syndromes $6,253,897
University of California, Los Angeles Aparna Bhaduri ReMIND – Discovery Stage ReMIND Defining Neurovascular Metabolism in Neurodevelopmental and Neuropsychiatric Disorders $10,330,000

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