Search all CIRM Grants

Institution Researcher name Grant Type Grant Title Award Value
Beckman Research Institute of City of Hope Yanhong Shi Early Translational II Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
University of California, Berkeley Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
Stanford University Michele Calos Early Translational II Stem Cell Therapy for Duchenne Muscular Dystrophy $2,267,900
Buck Institute for Age Research Xianmin Zeng Early Translational II Banking transplant ready dopaminergic neurons using a scalable process $4,998,871
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
University of California, Irvine leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,614,231
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology II Endothelial cells and ion channel maturation of human stem cell-derived cardiomyocytes $1,587,610
University of California, Davis Mark Zern Early Translational II Liver Cell Transplantation $4,215,748
Stanford University Michael Cleary Basic Biology IV Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells $1,244,455
The Salk Institute for Biological Studies Fred Gage Early Translational II Crosstalk: Inflammation in Parkinson’s disease (PD) in a humanized in vitro model $2,472,839
University of California, Los Angeles Noriyuki Kasahara Early Translational II Stem cell-based carriers for RCR vector delivery to glioblastoma $3,370,607
University of California, Davis Deborah Lieu Basic Biology IV Induction of Pluripotent Stem Cell-Derived Pacemaking Cells $1,333,800
Beckman Research Institute of City of Hope Yanhong Shi Basic Biology IV Modeling Alexander disease using patient-specific induced pluripotent stem cells $1,367,172
University of California, San Diego Catriona Jamieson Early Translational II Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy $3,103,041
University of California, San Francisco Miguel Ramalho-Santos Basic Biology IV Genetic dissection of human cellular reprogramming to pluripotency $1,184,883
Stanford University Ching-Pin Chang New Faculty II VEGF signaling in adventitial stem cells in vascular physiology and disease $3,008,076
University of California, San Diego Maike Sander Basic Biology IV Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,258,560
University of California, Irvine Leslie Thompson Early Translational II A hESc-based Development Candidate for Huntington's Disease $3,539,536
Buck Institute for Age Research Deepak Lamba Basic Biology IV 3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis $1,212,553
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology IV Studying Arrhythmogenic Right Ventricular Dysplasia with patient-specific iPS cells $1,582,606
University of California, San Diego Alysson Muotri Early Translational II Developing a drug-screening system for Autism Spectrum Disorders using human neurons $1,410,697
University of California, San Francisco Jeremy Reiter Basic Biology IV Modeling disease in human embryonic stem cells using new genetic tools $1,387,800
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
Beckman Research Institute of City of Hope David DiGiusto Early Translational II Development of RNA-based approaches to stem cell gene therapy for HIV $3,124,130
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
The J. David Gladstone Institutes Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,506,420
University of California, Los Angeles Sophie Deng Early Translational II Regeneration of Functional Human Corneal Epithelial Progenitor Cells $2,224,930
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
The J. David Gladstone Institutes Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,708,560
University of California, Irvine Henry Klassen Early Translational II Human retinal progenitor cells as candidate therapy for retinitis pigmentosa $1,803,768
University of California, Los Angeles Kathrin Plath Basic Biology IV Understanding the status of the X chromosomes in human ESCs and preimplantation embryos $1,382,400
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
Scripps Research Institute Peter Schultz Early Translational II Cartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis $6,180,114
The J. David Gladstone Institutes Sheng Ding Basic Biology IV A new paradigm of lineage-specific reprogramming $1,708,560
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
iPierian, Inc. John Dimos Early Translational II New Drug Discovery for SMA using Patient-derived Induced Pluripotent Stem Cells $2,410,000
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
University of California, Davis Roslyn Isseroff Early Translational II Bone Marrow Mesenchymal Stem Cells to Heal Chronic Diabetic Wounds $4,635,576
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
Children's Hospital of Los Angeles Markus Muschen Early Translational II Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication $850,769
Stanford University Roel Nusse Basic Biology IV Asymmetric stem cell division oriented by a local self-renewing signal $1,039,058
University of California, San Francisco Markus Muschen Early Translational II Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication $2,756,536
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
University of California, San Francisco Arturo Alvarez-Buylla Early Translational II Inhibitory Nerve Cell Precursors: Dosing, Safety and Efficacy $1,564,016
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,260,360
University of California, Los Angeles Bruno Peault Early Translational II Harnessing native fat-residing stem cells for bone regeneration $5,359,076
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of California, Irvine Brian Cummings Early Translational II Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,517,767
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,285,214
Cedars-Sinai Medical Center Dan Gazit Early Translational II Systemic Adult Stem Cell Therapy for Osteoporosis-Related Vertebral Compression Fractures $1,927,698
Stanford University Robert Negrin Transplantation Immunology Regulatory T cell induced tolerance to ESC transplantation $1,383,147
University of California, Los Angeles Donald Kohn Disease Team Research I Stem Cell Gene Therapy for Sickle Cell Disease $8,834,129
The Parkinson's Institute R. Jeremy Nichols Basic Biology III Understanding the role of LRRK2 in iPSC cell models of Parkinson's Disease $1,482,822
Beckman Research Institute of City of Hope Jiing-Kuan Yee Basic Biology III Use of human iPS cells to study spinal muscular atrophy $1,268,868
University of California, Berkeley Song Li Basic Biology III Induced Pluripotent Stem Cells for Tissue Regeneration $1,209,148
University of California, Los Angeles Ali Nsair Basic Biology III Characterization and Engineering of the Cardiac Stem Cell Niche $1,172,964
University of California, San Diego Anirvan Ghosh Basic Biology III Investigation of synaptic defects in autism using patient-derived induced pluripotent stem cells $843,597
Stanford University Aaron Hsueh Basic Biology III Correlated time-lapse imaging and single cell molecular analysis of human embryo development $1,260,122
University of California, Los Angeles Kathrin Plath Basic Biology III Discovery of mechanisms that control epigenetic states in human reprogramming and pluripotent cells $1,364,598
University of California, San Diego Eugene Yeo Basic Biology III Neural and general splicing factors control self-renewal, neural survival and differentiation $1,287,619
Stanford University Joanna Wysocka Basic Biology III Enhancer-mediated gene regulation during early human embryonic development $1,425,600
University of California, San Diego Farah Sheikh Basic Biology III Molecular Mechanisms Underlying Human Cardiac Cell Junction Maturation and Disease Using Human iPSC $1,341,955
University of California, San Diego David Cheresh Basic Biology III Molecular basis of human ES cell neurovascular differentiation and co-patterning $1,359,996
University of California, San Diego Charles King Basic Biology III Biological relevance of microRNAs in hESC differentiation to endocrine pancreas $1,313,649
University of California, Los Angeles Gay Crooks Basic Biology III Forming the Hematopoietic Niche from Human Pluripotent Stem Cells $1,252,857
Stanford University Sean Wu Basic Biology III Elucidating Molecular Basis of Hypertrophic Cardiomyopathy with Human Induced Pluripotent Stem Cells $1,264,248
The J. David Gladstone Institutes Deepak Srivastava Basic Biology III Mechanisms of Direct Cardiac Reprogramming $1,708,560
Scripps Research Institute Joel Gottesfeld Basic Biology III Triplet Repeat Instability in Human iPSCs $1,755,861
University of California, San Francisco Jason Pomerantz Basic Biology III Phenotypic Analysis of Human ES Cell-Derived Muscle Stem Cells $1,381,296
University of California, Los Angeles William Lowry Basic Biology III Molecular determinants of accurate differentiation from human pluripotent stem cells $677,115
University of California, Los Angeles Yi Sun Basic Biology III Studying neurotransmission of normal and diseased human ES cell-derived neurons in vivo $1,382,400
University of California, Los Angeles Shuo Lin Basic Biology III Etsrp/ER71 mediated stem cell differentiation into vascular lineage $1,382,400
Stanford University Michael Clarke Basic Biology III USP16 controls stem cell number: implications for Down Syndrome $1,264,032
Scripps Research Institute Kristin Baldwin Basic Biology III Identifying sources of mutation in human induced pluripotent stem cells by whole genome sequencing $1,755,864
University of California, San Diego Deborah Spector Basic Biology III Viral-host interactions affecting neural differentiation of human progenitors $1,372,660
University of California, San Francisco John Murnane Basic Biology III Genomic instability during culturing of human embryonic stem cells $1,070,919
University of California, San Diego Kun Zhang Basic Biology III Functional characterization of mutational load in nuclear reprogramming and differentiation $1,295,318
University of California, Berkeley Michael Rape Basic Biology III Ubiquitin-dependent control of hESC self-renewal and expansion $1,224,805
University of California, San Diego Binhai Zheng Basic Biology III Generation and characterization of corticospinal neurons from human embryonic stem cells $1,355,063
University of California, Merced Kara McCloskey New Faculty II Building Cardiac Tissue from Stem Cells and Natural Matrices $1,656,705
Sanford-Burnham Medical Research Institute Robert Wechsler-Reya Research Leadership 1 The role of neural stem cells in cerebellar development, regeneration and tumorigenesis $5,226,050
University of California, Los Angeles Brigitte Gomperts New Faculty II Stem Cells in Lung Cancer $2,381,572
The J. David Gladstone Institutes Eric Verdin SEED Grant Role of HDAC in human stem cells pluripotentiality and differentiation $590,997
University of California, Los Angeles Yong Kim Basic Biology II Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
University of California, San Diego Martin Marsala Transplantation Immunology Induction of immune tolerance after spinal grafting of human ES-derived neural precursors $1,387,800
University of California, San Francisco Samuel Pleasure Comprehensive Grant Human stem cell derived oligodendrocytes for treatment of stroke and MS $2,459,235
University of California, San Francisco Miguel Ramalho-Santos SEED Grant Transcriptional Regulation of Human Embryonic Stem Cells $595,755
Scripps Research Institute Jeanne Loring Early Translational I Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation $5,830,771
Stanford University Joanna Wysocka SEED Grant Role of Chromatin Modifiers in Regulating Human Embryonic Stem Cell Pluripotency $629,952
Children's Hospital of Los Angeles Elizabeth Lawlor SEED Grant hESC as tools to investigate the neural crest origin of Ewing's sarcoma $595,576
The J. David Gladstone Institutes Sheng Ding New Cell Lines Derivation of New ICM-stage hESCs $778,859
Sanford-Burnham Medical Research Institute Stuart Lipton Comprehensive Grant MEF2C-Directed Neurogenesis From Human Embryonic Stem Cells $2,832,000
University of California, San Francisco Su Guo SEED Grant Identifying small molecules that stimulate the differentiation of hESCs into dopamine-producing neurons $542,619
Stanford University Steven Artandi Basic Biology II Self-renewal and senescence in iPS cells derived from patients with a stem cell disease $931,285
University of California, Davis William Murphy Transplantation Immunology Donor natural killer (NK) cells as “veto” cells to promote donor-specific tolerance $1,257,601
University of California, Los Angeles Zack Jerome Comprehensive Grant Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,401,903
University of California, Santa Cruz Bin Chen SEED Grant In vitro differentiation of hESCs into corticospinal motor neurons $465,624
ViaCyte, Inc. Olivia Kelly Early Translational I Methods for detection and elimination of residual human embryonic stem cells in a differentiated cell product $5,405,397
The J. David Gladstone Institutes Warner Greene SEED Grant The APOBEC3 Gene Family as Guardians of Genome Stability in Human Embryonic Stem Cells $717,363

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