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Information about disease focus, human stem cell use or new cell line generation will typically not be available on the website until a few months after the award is announced. Disease categories are provided for awards that might impact a given disease or related area, whether those awards are for translational research on new therapy candidates or for basic research to address a biological question that is relevant to that disease.
Institution Researcher name Grant Type Grant Title ICOC Approved Funds
Stanford University Michele Calos Early Translational II Stem Cell Therapy for Duchenne Muscular Dystrophy $2,325,933
University of California, Irvine leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,614,441
La Jolla Institute for Allergy and Immunology Anjana Rao Transplantation Immunology Generation of regulatory T cells by reprogramming $1,503,998
University of California, Los Angeles Gay Crooks Comprehensive Grant Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $2,551,088
University of California, San Diego Dong-Er Zhang Basic Biology II RUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells $1,371,540
University of California, San Francisco Holger Willenbring New Faculty II Molecular dissection of adult liver regeneration to guide the generation of hepatocytes from pluripotent stem cells $3,207,510
Sanford-Burnham Medical Research Institute Mark Mercola Comprehensive Grant Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes $3,036,002
University of California, Davis Mark Zern Comprehensive Grant An in vitro and in vivo comparison among three different human hepatic stem cell populations $2,504,614
University of California, San Diego Kun-Liang Guan Basic Biology II The function of YAP in human embryonic stem cells $1,340,565
The J. David Gladstone Institutes Yadong Huang New Faculty II Defining the Isoform-Specific Effects of Apolipoprotein E on the Development of iPS Cells into Functional Neurons in Vitro and in Vivo $2,847,600
Stanford University Christopher Contag Transplantation Immunology Engineering Embryonic Stem Cell Allografts for Operational Tolerance $1,447,956
Stanford University Stefan Heller Comprehensive Grant Generation of inner ear sensory cells from human ES cells toward a cure for deafness $2,469,373
University of California, Los Angeles Benhur Lee Basic Biology II The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
University of California, San Diego Benjamin Yu New Faculty II Regulation of Adult Stem Cell Proliferation by RAS and Cell-Permeable Proteins $3,231,649
University of California, San Francisco Randall Lee Comprehensive Grant Embryonic Stem Cell-Derived Therapies Targeting Cardiac Ischemic Disease $2,524,617
Stanford University Aaron Hsueh Basic Biology II Maturation of Human Oocytes for SCNT and Embryonic Stem Cell Derivation $1,432,197
Stanford University Ching-Pin Chang New Faculty II VEGF signaling in adventitial stem cells in vascular physiology and disease $3,330,931
Scripps Research Institute Jeanne Loring Transplantation Immunology Thymus based tolerance to stem cell therapies $1,269,844
Stanford University Roel Nusse Comprehensive Grant Guiding the developmental program of human embryonic stem cells by isolated Wnt factors $2,354,820
The Salk Institute for Biological Studies Ronald Evans Basic Biology II Molecular Characterization and Functional Exploration of Nuclear Receptors in hiPSCs $1,712,880
University of California, San Diego Catriona Jamieson New Faculty II Derivation and Characterization of Myeloproliferative Disorder Stem Cells from Human ES Cells $3,065,572
University of California, Davis Alice Tarantal Comprehensive Grant Preclinical Model for Labeling, Transplant, and In Vivo Imaging of Differentiated Human Embryonic Stem Cells $2,257,040
iPierian, Inc. John Dimos Basic Biology II Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency $1,458,000
University of California, Irvine Edwin Monuki New Faculty II Mechanisms in Choroid Plexus Epithelial Development $3,169,328
University of California, San Francisco Jeffrey Bluestone Transplantation Immunology Stem cell tolerance through the use of engineered antigen-specific regulatory T cells $1,152,768
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,570,000
University of California, Davis Eric Kurzrock Basic Biology II Differentiation of Human Embryonic Stem Cells into Urothelium $1,328,400
University of Southern California Gage DeKoeyer Crump New Faculty II Skeletogenic Neural Crest Cells in Embryonic Development and Adult Regeneration of the Jaw $2,396,871
University of California, San Francisco Tippi MacKenzie Transplantation Immunology Maternal and Fetal Immune Responses to In Utero Hematopoietic Stem Cell Transplantation $1,324,229
Stanford University Julie Baker Comprehensive Grant Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,628,635
University of California, San Francisco Jeremy Reiter New Faculty II High throughput modeling of human neurodegenerative diseases in embryonic stem cells $2,259,092
University of California, San Francisco Harold Bernstein Comprehensive Grant Modeling Myocardial Therapy with Human Embryonic Stem Cells $2,229,140
University of California, Merced Kara McCloskey New Faculty II Building Cardiac Tissue from Stem Cells and Natural Matrices $1,706,255
Stanford University Theo Palmer Comprehensive Grant Immunology of neural stem cell fate and function $2,501,125
University of California, Davis Paul Knoepfler New Faculty II Molecular mechanisms governing hESC and iPS cell self-renewal and pluripotency $2,158,161
University of California, San Francisco Samuel Pleasure Comprehensive Grant Human stem cell derived oligodendrocytes for treatment of stroke and MS $2,566,701
University of California, Berkeley Lin He New Faculty II The roles of non-coding RNAs in the self-renewal and differentiation of pluripotent stem cells $1,499,994
University of California, Los Angeles Zack Jerome Comprehensive Grant Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,516,831
University of California, San Diego Mana Parast New Faculty II Molecular Mechanisms of Trophoblast Stem Cell Specification and Self-Renewal $3,253,580
Scripps Research Institute Nicholas Gascoigne Transplantation Immunology Role of Innate Immunity in hematopoeitic stem cell-mediated allograft tolerance $1,746,684
Stanford University Christopher Zarins Comprehensive Grant Engineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells $2,618,704
University of California, San Francisco Ophir Klein New Faculty II Laying the groundwork for building a tooth: analysis of dental epithelial stem cells $3,250,251
Palo Alto Institute for Research and Education, Inc. Tony Wyss-Coray Basic Biology II Systemic Protein Factors as Modulators of the Aging Neurogenic Niche $1,522,800
University of California, Irvine Hans Keirstead Comprehensive Grant hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,396,932
University of California, San Francisco Emmanuelle Passegue New Faculty II Mechanisms Underlying the Responses of Normal and Cancer Stem Cells to Environmental and Therapeutic Insults $2,274,368
University of California, Los Angeles Douglas Black Basic Biology II Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,350,994
University of California, San Francisco Arnold Kriegstein Comprehensive Grant Derivation of Inhibitory Nerve Cells from Human Embryonic Stem Cells $2,507,223
University of Southern California Qilong Ying New Faculty II Mechanisms Underlying the Diverse Functions of STAT3 in Embryonic Stem Cell Fate Regulation $2,413,650
University of California, Los Angeles Yong Kim Basic Biology II Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
University of California, Los Angeles Antoni Ribas New Faculty II Stem Cells for Immune System Regeneration to Fight Cancer $3,247,000
Stanford University Renee Reijo Pera Comprehensive Grant Human oocyte development for genetic, pharmacological and reprogramming applications $2,469,104
San Diego State University Ricardo Zayas New Faculty II The molecular basis underlying adult neurogenesis during regeneration and tissue renewal $1,725,830
Stanford University Steven Artandi Basic Biology II Self-renewal and senescence in iPS cells derived from patients with a stem cell disease $1,430,908
The J. David Gladstone Institutes Benoit Bruneau New Faculty II Induction of cardiogenesis in pluripotent cells via chromatin remodeling factors $2,847,600
The J. David Gladstone Institutes Deepak Srivastava Comprehensive Grant microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells $3,164,000
Escape Therapeutics, Inc Basil Hantash Transplantation Immunology Development of an immune tolerant hESC source for allogeneic cell therapy applications $1,453,040
Sanford-Burnham Medical Research Institute Stuart Lipton Comprehensive Grant MEF2C-Directed Neurogenesis From Human Embryonic Stem Cells $3,035,996
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology II Endothelial cells and ion channel maturation of human stem cell-derived cardiomyocytes $1,823,362
University of California, Los Angeles Brigitte Gomperts New Faculty II Stem Cells in Lung Cancer $2,556,572
University of California, Los Angeles Guoping Fan Comprehensive Grant Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair $2,516,613
Palo Alto Institute for Research and Education, Inc. Husein Hadeiba Transplantation Immunology Application of Tolerogenic Dendritic Cells for Hematopoietic Stem Cell Transplantation $885,475
Stanford University Irving Weissman Comprehensive Grant Prospective isolation of hESC-derived hematopoietic and cardiomyocyte stem cells $2,636,900
University of California, San Francisco John Rubenstein Basic Biology II MGE Enhancers to Select for Interneuron Precursors Produced from Human ES Cells $1,387,800
Ludwig Institute for Cancer Research Bing Ren New Faculty II Mechanisms of chromatin dynamics at enhancers during ES cell differentiation $1,726,564
University of California, San Francisco Susan Fisher Comprehensive Grant Constructing a fate map of the human embryo $2,532,388
University of California, Los Angeles Gay Crooks Transplantation Immunology Engineering Thymic Regeneration to Induce Tolerance $1,357,398
University of California, Irvine Peter Donovan Comprehensive Grant Improved hES Cell Growth and Differentiation $2,509,438
Stanford University Garry Nolan Basic Biology II Kinase signaling analysis of iPS cell reprogramming and differentiation $1,447,956
University of California, San Diego Shyni Varghese New Faculty II A Novel Microenvironment-Mediated Functional Skeletal Muscle from Human Embryonic Stem Cells and their In Vivo Engraftment $2,300,569
The Salk Institute for Biological Studies Fred Gage Comprehensive Grant Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons $2,879,210
University of California, San Francisco Andrew Leavitt Comprehensive Grant Understanding hESC-based Hematopoiesis for Therapeutic Benefit $2,566,702
University of California, Irvine Aileen Anderson Basic Biology II Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,284,921
University of California, San Francisco Robert Blelloch New Faculty II Mechanisms of small RNA regulation in early embryonic development $3,204,897
University of California, San Diego Lawrence Goldstein Comprehensive Grant Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer's Disease $2,512,664
University of California, San Francisco Mark Anderson Transplantation Immunology Stem cell differentiation to thymic epithelium for inducing tolerance to stem cells $1,314,090
University of California, Irvine Douglas Wallace Comprehensive Grant The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $2,530,000
University of California, Irvine Marian Waterman Basic Biology II TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal $1,277,101
Children's Hospital of Los Angeles Tracy Grikscheit New Faculty II Mechanism of Tissue Engineered Small Intestine Formation $3,415,000
University of California, San Diego Martin Marsala Comprehensive Grant Spinal ischemic paraplegia: modulation by human embryonic stem cell implant $2,445,716
Calimmune, Inc. Geoff Symonds Disease Team Research I GENE-MODIFIED HEMATOPOIETIC STEM/PROGENITOR CELL BASED THERAPY FOR HIV DISEASE $8,278,722
University of California, Los Angeles Irvin Chen Early Translational from Disease Team Conversion HPSC based therapy for HIV disease using RNAi to CCR5. $1,505,000
University of California, San Diego Dennis Carson Disease Team Research I Development of Highly Active Anti-Leukemia Stem Cell Therapy (HALT) $19,999,826
Stanford University Alfred Lane Disease Team Research I iPS Cell-Based Treatment of Dominant Dystrophic Epidermolysis Bullosa $11,709,574
Beckman Research Institute of City of Hope Karen Aboody Disease Team Research I Stem Cell-mediated Therapy for High-grade Glioma: Toward Phase I-II Clinical Trials $18,015,429
Stanford University Gary Steinberg Disease Team Research I Embryonic-Derived Neural Stem Cells for Treatment of Motor Sequelae following Sub-cortical Stroke $20,000,000
University of California, Los Angeles Dennis Slamon Disease Team Research I THERAPEUTIC OPPORTUNITIES TO TARGET TUMOR INITIATING CELLS IN SOLID TUMORS $19,979,660
University of California, Los Angeles Donald Kohn Disease Team Research I Stem Cell Gene Therapy for Sickle Cell Disease $9,212,365
Stanford University Irving Weissman Disease Team Research I Development of Therapeutic Antibodies Targeting Human Acute Myeloid Leukemia Stem Cells $19,999,996
ViaCyte, Inc. Allan Robins Disease Team Research I Cell Therapy for Diabetes $22,999,937
Cedars-Sinai Medical Center Eduardo Marbán Disease Team Research I Autologous cardiac-derived cells for advanced ischemic cardiomyopathy $5,560,232
Beckman Research Institute of City of Hope John Zaia Disease Team Research I ZIinc Finger Nuclease-Based Stem Cell Therapy for AIDS $14,583,187
University of California, Los Angeles Irvin Chen Disease Team Research I HPSC based therapy for HIV disease using RNAi to CCR5. $9,905,604
University of California, San Francisco Mitchel Berger Disease Team Research I Stem Cell-Mediated Oncocidal Gene Therapy of Glioblastoma (GBM) $19,162,435
University of Southern California Mark Humayun Disease Team Research I Stem cell based treatment strategy for Age-related Macular Degeneration (AMD) $18,904,916
University of California, San Diego Lawrence Goldstein Disease Team Research I Stem Cell-Derived Astrocyte Precursor Transplants in Amyotrophic Lateral Sclerosis $10,857,762
Children's Hospital of Los Angeles David Warburton Shared Labs hESC Facility $3,756,666
University of Southern California Andrew McMahon Shared Labs Center for Stem Cell and Regenerative Medicine: Shared Research Laboratory and Course in Current Protocols in Human Embryonic Stem Cell Research $5,355,969
University of California, San Francisco Linda Giudice Shared Labs Shared Research and Teaching Laboratory: a Non-Federal Human Embryonic Stem Cell Resource for the Bay Area Community $5,546,877
University of California, Santa Barbara Dennis Clegg Shared Labs Laboratory for Stem Cell Biology and Engineering $3,161,329
University of California, Davis Alice Tarantal Shared Labs Translational Human Embryonic Stem Cell Shared Research Facility $3,709,631
Total:
$425,522,124.00

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