Search all CIRM Grants

Institution Researcher name Grant Type Grant Title Approved funds
Sanford-Burnham Medical Research Institute Evan Snyder Early Translational I Developmental Candidates for Cell-Based Therapies for Parkinson's Disease (PD) $5,190,752
The Salk Institute for Biological Studies Emmanuelle Passegue Shared Labs CIRM Shared Research Laboratory for Stem Cells and Aging $2,414,749
The Salk Institute for Biological Studies Ronald Evans Basic Biology II Molecular Characterization and Functional Exploration of Nuclear Receptors in hiPSCs $1,712,880
iPierian, Inc. Irene Griswold-Prenner Basic Biology II Cellular Reprogramming: Dissecting the Molecular Mechanism and Enhancing Efficiency $1,458,000
University of California, Davis Eric Kurzrock Basic Biology II Differentiation of Human Embryonic Stem Cells into Urothelium $849,037
Palo Alto Institute for Research and Education, Inc. Tony Wyss-Coray Basic Biology II Systemic Protein Factors as Modulators of the Aging Neurogenic Niche $1,159,812
University of California, Los Angeles Douglas Black Basic Biology II Programs of alternative splicing regulation by polypyrimidine tract binding protein $1,344,562
University of California, Los Angeles Yong Kim Basic Biology II Novel Mechanism in Self-Renewal/Differentiation of Human Embryonic Stem Cells $1,259,371
Sanford-Burnham Medical Research Institute Huei-sheng Chen Basic Biology II Endothelial cells and ion channel maturation of human stem cell-derived cardiomyocytes $1,587,610
Stanford University Garry Nolan Basic Biology II Kinase signaling analysis of iPS cell reprogramming and differentiation $1,343,789
University of California, Irvine Aileen Anderson Basic Biology II Role of the microenvironment in human iPS and NSC fate and tumorigenesis $1,256,194
University of California, Irvine Marian Waterman Basic Biology II TCF-3: A Wnt Pathway Effector and Nanog Regulator in Pluripotent Stem Cell Self-Renewal $1,277,101
University of California, San Diego Dong-Er Zhang Basic Biology II RUNX1 in maintenance, expansion, and differentiation of therapeutic pluripotent stem cells $1,371,540
University of California, San Diego Kun-Liang Guan Basic Biology II The function of YAP in human embryonic stem cells $1,245,693
University of California, Los Angeles Benhur Lee Basic Biology II The EphrinB2/EphB4 axis in regulating hESC pluripotency and differentiation $1,371,936
Stanford University Aaron Hsueh Basic Biology II Maturation of Human Oocytes for SCNT and Embryonic Stem Cell Derivation $1,309,018
University of California, Davis Alice Tarantal Early Translational I In Utero Model to Assess the Fate of Transplanted Human Cells for Translational Research and Pediatric Therapies $4,214,592
BioTime, Inc. Michael West Early Translational I Addressing the Cell Purity and Identity Bottleneck Through Generation and Expansion of Clonal Human Embryonic Progenitor Cell Lines $4,721,706
University of California, Davis Jan Nolta Early Translational I Sustained siRNA production from human MSC to treat Huntingtons Disease and other neurodegenerative disorders $2,615,674
University of California, Irvine Frank LaFerla Early Translational I Neural Stem Cells as a Developmental Candidate to Treat Alzheimer Disease $3,599,997
University of California, San Diego Yang Xu Early Translational I Developing induced pluripotent stem cells into human therapeutics and disease models $5,165,028
Scripps Research Institute Jeanne Loring Early Translational I Ensuring the safety of cell therapy: a quality control pipeline for cell purification and validation $5,830,771
ViaCyte, Inc. Olivia Kelly Early Translational I Methods for detection and elimination of residual human embryonic stem cells in a differentiated cell product $5,405,397
Scripps Health Darryl D'Lima Early Translational I Stem Cell-Based Therapy for Cartilage Regeneration and Osteoarthritis $3,118,431
Scripps Research Institute Martin Friedlander Early Translational I Autologous Retinal Pigmented Epithelial Cells Derived from Induced Pluripotent Stem Cells for the Treatment of Atrophic Age Related Macular Degeneration $5,866,528
The J. David Gladstone Institutes Warner Greene Early Translational I Maximizing the Safety of Induced Pluripotent Stem Cells as an Infusion Therapy: Limiting the Mutagenic Threat of Retroelement Retrotransposition during iPSC Generation, Expansion and Differentiation $1,324,011
The Jackson Laboratory West Pali Kaur Early Translational I Mouse Models for Stem Cell Therapeutic Development $3,833,303
The Parkinson's Institute J. William Langston Early Translational I Using patient-specific iPSC derived dopaminergic neurons to overcome a major bottleneck in Parkinson's disease research and drug discovery $3,698,646
Stanford University Michael Longaker Early Translational I Enhancing healing via Wnt-protein mediated activation of endogenous stem cells $5,964,258
University of California, Los Angeles Gabriel Travis Early Translational I Development of a Stem Cell-based Transplantation Strategy for Treating Age-related Macular Degeneration $5,479,028
The Salk Institute for Biological Studies Inder Verma Early Translational I Curing Hematological Diseases $5,979,252
Stanford University Gerald Crabtree Basic Biology IV Mechanism and Utility of Direct Neuronal Conversion with a MicroRNA-Chromatin Switch $1,392,426
iPierian, Inc. John Dimos Early Translational II New Drug Discovery for SMA using Patient-derived Induced Pluripotent Stem Cells $2,410,000
University of California, Los Angeles Owen Witte Basic Biology IV Trop2 dependent and independent mechanisms of self-renewal in human cancer stem cells $1,254,960
University of California, San Diego Ananda Goldrath Basic Biology IV Mechanisms to protect hESC-derived cells from allogenic immune rejection $1,161,000
University of California, San Diego David Traver Basic Biology IV DECIPHERING THE INSTRUCTIONS FOR VERTEBRATE HSC SPECIFICATION AND AMPLIFICATION. $1,363,698
University of California, San Francisco Markus Muschen Early Translational II Dual targeting of tyrosine kinase and BCL6 signaling for leukemia stem cell eradication $3,607,305
Stanford University Michelle Monje Basic Biology IV Stem Cell Mechanisms Governing Discrete Waves of Gliogenesis in the Childhood Brain $1,264,248
University of California, San Diego Eugene Yeo Basic Biology IV Stem cell models to analyze the role of mutated C9ORF72 in neurodegeneration $1,260,360
University of California, Los Angeles Bruno Peault Early Translational II Harnessing native fat-residing stem cells for bone regeneration $5,359,076
Cedars-Sinai Medical Center Eduardo Marbán Basic Biology IV Mechanism of heart regeneration by cardiosphere-derived cells $1,367,604
University of California, Irvine Brian Cummings Early Translational II Neural restricted, FAC-sorted, human neural stem cells to treat traumatic brain injury $1,517,767
University of California, San Francisco Barbara Panning Basic Biology IV Investigation of the role of O-GlcNAcylation in SOX2 function during reprogramming $1,285,214
Cedars-Sinai Medical Center Dan Gazit Early Translational II Systemic Adult Stem Cell Therapy for Osteoporosis-Related Vertebral Compression Fractures $1,927,698
Beckman Research Institute of City of Hope Yanhong Shi Early Translational II Developing a therapeutic candidate for Canavan disease using induced pluripotent stem cell $1,835,983
University of California, Berkeley Robert Tjian Basic Biology IV Transcriptional regulation of pluripotency in human embryonic stem cells $1,220,968
Stanford University Michele Calos Early Translational II Stem Cell Therapy for Duchenne Muscular Dystrophy $2,267,900
Stanford University Anne Brunet Basic Biology IV Energy metabolism and aging pathways in human stem cell reprogramming and differentiation $1,414,044
University of California, Irvine leif Havton Early Translational II Repair of Conus Medullaris/Cauda Equina Injury using Human ES Cell-Derived Motor Neurons $1,614,231
University of California, Davis Mark Zern Early Translational II Liver Cell Transplantation $4,216,113
Stanford University Michael Cleary Basic Biology IV Prostaglandin pathway regulation of self-renwal in hematopoietic and leukemia stem cells $1,244,455
The Salk Institute for Biological Studies Fred Gage Early Translational II Crosstalk: Inflammation in Parkinson’s disease (PD) in a humanized in vitro model $2,472,839
University of California, Los Angeles Noriyuki Kasahara Early Translational II Stem cell-based carriers for RCR vector delivery to glioblastoma $3,370,607
University of California, Davis Deborah Lieu Basic Biology IV Induction of Pluripotent Stem Cell-Derived Pacemaking Cells $1,333,800
University of California, San Diego Catriona Jamieson Early Translational II Preclinical development of a pan Bcl2 inhibitor for cancer stem cell directed therapy $3,103,041
University of California, San Francisco Miguel Ramalho-Santos Basic Biology IV Genetic dissection of human cellular reprogramming to pluripotency $1,184,883
University of California, San Diego Maike Sander Basic Biology IV Deciphering transcriptional control of pancreatic beta-cell maturation in vitro $1,258,560
University of California, Irvine Leslie Thompson Early Translational II A hESc-based Development Candidate for Huntington's Disease $3,539,536
Buck Institute for Age Research Deepak Lamba Basic Biology IV 3D Modeling of Retina using Polymer Scaffolds for Understanding Disease Pathogenesis $1,212,553
University of California, San Diego Alysson Muotri Early Translational II Developing a drug-screening system for Autism Spectrum Disorders using human neurons $1,407,535
Stanford University Howard Chang Basic Biology IV Long noncoding RNAs for pluripotency and cell fate commitment $1,386,627
Stanford University Alexander Dunn Basic Biology IV Role of mechanical signaling in stem cell self-renewal and differentiation $1,064,224
The J. David Gladstone Institutes Steven Finkbeiner Basic Biology IV Common molecular mechanisms in neurodegenerative diseases using patient based iPSC neurons $1,506,420
University of California, San Diego George Sen Basic Biology IV Regulation of Epidermal Self-Renewal and Differentiation by Histone and DNA Demethylases. $1,080,000
The J. David Gladstone Institutes Benoit Bruneau Basic Biology IV Epigenetic regulation of human cardiac differentiation $1,708,560
University of California, Irvine Henry Klassen Early Translational II Human retinal progenitor cells as candidate therapy for retinitis pigmentosa $1,803,768
University of California, San Diego Miles Wilkinson Basic Biology IV Role of the NMD RNA Decay Pathway in Maintaining the Stem-Like State $1,360,450
Scripps Research Institute Peter Schultz Early Translational II Cartilage Regeneration by the Chondrogenic Small Molecule PRO1 during Osteoarthritis $6,180,114
The J. David Gladstone Institutes Sheng Ding Basic Biology IV A new paradigm of lineage-specific reprogramming $1,708,560
University of California, San Diego Martin Marsala Comprehensive Grant Spinal ischemic paraplegia: modulation by human embryonic stem cell implant $2,356,090
University of California, Davis Alice Tarantal Comprehensive Grant Preclinical Model for Labeling, Transplant, and In Vivo Imaging of Differentiated Human Embryonic Stem Cells $2,166,757
Sanford-Burnham Medical Research Institute Mark Mercola Comprehensive Grant Chemical Genetic Approach to Production of hESC-derived Cardiomyocytes $2,832,000
University of California, San Diego Yang Xu Comprehensive Grant Mechanisms to maintain the self-renewal and genetic stability of human embryonic stem cells $2,467,200
Stanford University Julie Baker Comprehensive Grant Functional Genomic Analysis of Chemically Defined Human Embryonic Stem Cell $2,518,303
University of California, San Francisco Harold Bernstein Comprehensive Grant Modeling Myocardial Therapy with Human Embryonic Stem Cells $2,134,694
Stanford University Theo Palmer Comprehensive Grant Immunology of neural stem cell fate and function $2,396,000
University of California, San Francisco Samuel Pleasure Comprehensive Grant Human stem cell derived oligodendrocytes for treatment of stroke and MS $2,459,235
University of California, Los Angeles Zack Jerome Comprehensive Grant Human Embryonic Stem Cell Therapeutic Strategies to Target HIV Disease $2,401,903
Sanford-Burnham Medical Research Institute Stuart Lipton Comprehensive Grant MEF2C-Directed Neurogenesis From Human Embryonic Stem Cells $2,832,000
Stanford University Christopher Zarins Comprehensive Grant Engineering a Cardiovascular Tissue Graft from Human Embryonic Stem Cells $2,454,490
Stanford University Irving Weissman Comprehensive Grant Prospective isolation of hESC-derived hematopoietic and cardiomyocyte stem cells $2,471,386
University of California, Irvine Hans Keirstead Comprehensive Grant hESC-Derived Motor Neurons For the Treatment of Cervical Spinal Cord Injury $2,158,445
University of California, Irvine Peter Donovan Comprehensive Grant Improved hES Cell Growth and Differentiation $2,381,713
University of California, San Francisco Andrew Leavitt Comprehensive Grant Understanding hESC-based Hematopoiesis for Therapeutic Benefit $2,460,822
Stanford University Renee Reijo Pera Comprehensive Grant Human oocyte development for genetic, pharmacological and reprogramming applications $2,300,699
University of California, Irvine Douglas Wallace Comprehensive Grant The Dangers of Mitochondrial DNA Heteroplasmy in Stem Cells Created by Therapeutic Cloning $1,790,133
The J. David Gladstone Institutes Deepak Srivastava Comprehensive Grant microRNA Regulation of Cardiomyocyte Differentiation from Human Embryonic Stem Cells $2,994,719
University of California, Los Angeles Gay Crooks Comprehensive Grant Regulated Expansion of Lympho-hematopoietic Stem and Progenitor Cells from Human Embryonic Stem Cells (hESC) $2,229,410
University of California, Los Angeles Guoping Fan Comprehensive Grant Epigenetic gene regulation during the differentiation of human embryonic stem cells: Impact on neural repair $2,412,995
University of California, Davis Mark Zern Comprehensive Grant An in vitro and in vivo comparison among three different human hepatic stem cell populations $2,252,835
University of California, San Francisco Susan Fisher Comprehensive Grant Constructing a fate map of the human embryo $2,430,487
Stanford University Stefan Heller Comprehensive Grant Generation of inner ear sensory cells from human ES cells toward a cure for deafness $2,330,559
The Salk Institute for Biological Studies Fred Gage Comprehensive Grant Molecular and Cellular Transitions from ES Cells to Mature Functioning Human Neurons $2,749,293
University of California, San Francisco Randall Lee Comprehensive Grant Embryonic Stem Cell-Derived Therapies Targeting Cardiac Ischemic Disease $2,424,353
University of California, San Diego Lawrence Goldstein Comprehensive Grant Using Human Embryonic Stem Cells to Understand and to Develop New Therapies for Alzheimer's Disease $1,859,414
Stanford University Roel Nusse Comprehensive Grant Guiding the developmental program of human embryonic stem cells by isolated Wnt factors $1,710,817
University of Southern California Songtao Shi New Faculty I Oral and Craniofacial Reconstruction Using Mesenchymal Stem Cells $3,253,464
Stanford University Howard Chang New Faculty I Noncoding RNAs in Cell Fate Determination $2,985,894
University of California, San Diego David Traver New Faculty I Genetic dissection of mesodermal commitment to the hematopoietic fates. $2,150,620
University of California, Santa Cruz Bin Chen New Faculty I Molecular mechanisms of neural stem cell differentiation in the developing brain $2,147,592

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