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Institution
Researcher name
Grant Type
Grant Title
Award Value
X-Therma Inc.
Dr. Xiaoxi Wei
Quest – Discovery Stage Research Projects
Non-Toxic, Highly-Effective Bioinspired Cryoprotectants for On-Demand Stem Cell Therapies
$887,883
University of California, Los Angeles
Dr. Caroline Y. Kuo
Quest – Discovery Stage Research Projects
Targeted Gene Editing in the Treatment of X-Linked Hyper-IgM Syndrome
$1,512,333
University of California, Davis
Dr. Deborah K Lieu
Quest – Discovery Stage Research Projects
Microenvironment for hiPSC-derived pacemaking cardiomyocytes
$2,042,438
Stanford University
Dr. Mark Mercola
Quest – Discovery Stage Research Projects
Multipotent Cardiovascular Progenitor Regeneration of the Myocardium after MI
$1,809,234
University of California, San Diego
Professor Yuan Chen
Quest – Discovery Stage Research Projects
A Novel Approach to Eradicate Cancer Stem Cells
$279,977
City of Hope, Beckman Research Institute
Professor Yuan Chen
Quest – Discovery Stage Research Projects
A Novel Approach to Eradicate Cancer Stem Cells
$1,539,935
University of California, Berkeley
5106433559 Kevin E. Healy
Quest – Discovery Stage Research Projects
Human Cardiac Chip for Assessment of Proarrhythmic Risk
$899,581
University of California, San Francisco
Dr. Holger F Willenbring
Quest – Discovery Stage Research Projects
Preclinical development of AAV vector-mediated in vivo hepatic reprogramming of myofibroblasts as a therapy for liver fibrosis
$1,638,389
Scaled Biolabs Inc.
Dr Justin Cooper-White
Quest – Discovery Stage Research Projects
A tool for rapid development of clinical-grade protocols for dopaminergic neuronal differentiation of Parkinson’s Disease patient-derived iPSCs
$657,528
City of Hope, Beckman Research Institute
Markus Müschen
Quest – Discovery Stage Research Projects
Lgr5-mediated self-renewal in B cell selection and leukemia-initiation
$2,183,223
University of California, San Diego
Professor Alysson R Muotri
Quest – Discovery Stage Research Projects
A treatment for Zika virus infection and neuroprotection efficacy
$1,924,524
Stanford University
Dr. Matthew H Porteus
Quest – Discovery Stage Research Projects
Genome Editing to Correct Cystic Fibrosis Mutations in Airway Stem Cells
$1,968,456
University of California, San Francisco
Dr. Julie B Sneddon
Quest – Discovery Stage Research Projects
Designing a cellular niche for transplantation of human embryonic stem cell-derived beta cells
$2,006,076
University of California, Los Angeles
Dr. John P Chute
Quest – Discovery Stage Research Projects
Protein tyrosine phosphatase – sigma inhibitors for hematopoietic regeneration
$2,115,735
University of California, San Diego
Dan S Kaufman
Quest – Discovery Stage Research Projects
Targeted off-the-shelf immunotherapy to treat refractory cancers
$1,936,936
Parkinson’s Institute
Dr. Birgitt Schuele
Quest – Discovery Stage Research Projects
CRISPR/dCas9 mutant targeting SNCA promoter for downregulation of alpha-synuclein expression as a novel therapeutic approach for Parkinson’s disease
$1,288,415
Gladstone Institutes, J. David
Dr. Deepak Srivastava
Quest – Discovery Stage Research Projects
Direct Cardiac Reprogramming for Regenerative Medicine
$2,392,157
University of California, Irvine
Leslie M Thompson
Quest – Discovery Stage Research Projects
hNSC-mediated delivery of ApiCCT1 as a candidate therapeutic for Huntington’s disease
$1,650,263
Stanford University
Dr. Roel Nusse
Quest – Discovery Stage Research Projects
Preclinical development of human hepatocyte progenitor cells for cell therapy
$1,651,211
University of California, San Francisco
Dr. Tejal Ashwin Desai
Quest – Discovery Stage Research Projects
Thin Film Encapsulation Devices for Human Stem Cell derived Insulin Producing Cells
$1,092,063
Stanford University
Dr. Rosa Bacchetta
Quest – Discovery Stage Research Projects
GENE EDITING FOR FOXP3 IN HUMAN HSC
$984,228
California Institute of Technology
Dr. David Baltimore PhD
Quest – Discovery Stage Research Projects
Immunotherapy for HIV infection using engineered hematopoietic stem/progenitor cells
$1,569,193
Gladstone Institutes, J. David
Dr. Deepak Srivastava
Quest – Discovery Stage Research Projects
Use of Human iPSC-derived Endothelial Cells for Calcific Aortic Valve Disease Therapeutics
$2,400,048
Scripps Research Institute
Dr. Jeanne F Loring
Quest – Discovery Stage Research Projects
Autologous cell therapy for Parkinson’s disease using iPSC-derived DA neurons
$2,299,786
University of California, Davis
Dr. David J Segal PhD
Quest – Discovery Stage Research Projects
MSC delivery of an artificial transcription factor to the brain as a treatment for Angelman Syndrome
$1,055,319
University of California, Berkeley
Dr. David V. Schaffer
Quest – Discovery Stage Research Projects
Scalable, Defined Production of Oligodendrocyte Precursor Cells to Treat Neural Disease and Injury
$1,627,099
Stanford University
Professor Hiromitsu Nakauchi
Quest – Discovery Stage Research Projects
Novel Rejuvenated T Cell Immunotherapy for Lung Cancer
$1,968,456
University of California, Los Angeles
Dr. April Pyle Ph.D.
Quest – Discovery Stage Research Projects
CRISPR/Cas9 nanoparticle enabled therapy for Duchenne Muscular Dystrophy in muscle stem cells
$2,150,400
University of California, San Diego
Karl Karl J. Wahlin
Inception – Discovery Stage Research Projects
An IPSC cell based model of macular degeneration for drug discovery.
$232,200
University of California, Los Angeles
Alireza Moshaverinia
Inception – Discovery Stage Research Projects
Gingival mesenchymal stem cells as a novel treatment modality for periodontal tissue regeneration
$194,483
Zenobia Therapeutics
Vicki Nienaber
Inception – Discovery Stage Research Projects
A new phenotypic screening platform that identifies biologically-relevant targets and lead compounds for the treatment of Parkinson’s disease
$112,500
Cedars-Sinai Medical Center
Dmitriy Sheyn
Inception – Discovery Stage Research Projects
IVD rejuvenation using iPSC-derived notochordal cells
$241,992
Loma Linda University
Dr. David J Baylink
Inception – Discovery Stage Research Projects
Bone Marrow Targeting of Hematopoietic Stem Cells Engineered to Overexpress 25-OH-VD3 1-α-hydroxylase for Acute Myeloid Leukemia Therapy
$178,967
Palo Alto Veterans Institute for Research
Dr. Ngan F Huang
Inception – Discovery Stage Research Projects
iPSC-Derived Smooth Muscle Progenitors for Treatment of Abdominal Aortic Aneurysm
$172,621
University of California, Davis
Dr. Alice F Tarantal
Inception – Discovery Stage Research Projects
Enhanced Branching Morphogenesis and Pluripotent Cell Lineage Differentiation for Pediatric Regenerative Therapies
$235,800
Loma Linda University
Julia J. Unternaehrer-Hamm
Inception – Discovery Stage Research Projects
Targeting cancer stem cells with nanoparticle RNAi delivery to prevent recurrence and metastasis of ovarian cancer
$172,870
Human BioMolecular Research Institute
Dr. John R Cashman
Inception – Discovery Stage Research Projects
Human Pancreatic Cancer Stem Cells: Developing a Novel Drug for Cancer Eradication
$303,785
Stanford University
Professor Hiromitsu Nakauchi
Inception – Discovery Stage Research Projects
Optimizing self-renewal signaling kinetics to stabilize ex vivo hematopoietic stem cell expansion
$210,906
University of California, San Diego
Gerald P Morris
Inception – Discovery Stage Research Projects
Identification of antigenic neo-epitopes from in vitro reprogrammed human tissue precursors for regenerative therapy
$193,500
University of California, Davis
Alyssa Panitch PhD
Inception – Discovery Stage Research Projects
Development of treatments to improve healing of ischemic wounds
$235,099
Stanford University
Guillem Pratx
Inception – Discovery Stage Research Projects
Novel metabolic labeling method for tracking stem cells to irradiated salivary glands using PET
$229,227
University of California, San Francisco
Semil P Choksi
Inception – Discovery Stage Research Projects
Generation of human airway stem cells by direct transcriptional reprogramming for disease modeling and regeneration
$238,408
University of California, Irvine
Janet E Baulch
Inception – Discovery Stage Research Projects
An exosome-based translational strategy to mitigate Alzheimer’s disease neuropathology
$157,650
University of California, San Diego
Dr. Tannishtha Reya
Inception – Discovery Stage Research Projects
Reprogramming human stem cells for blood cell generation
$210,060
Stanford University
Dr. Helen M Blau
Inception – Discovery Stage Research Projects
Prodrug innovation to target muscle stem cells and enhance muscle regeneration
$235,834
Sanford Burnham Prebys Medical Discovery Institute
Dr Alessandra Sacco
Inception – Discovery Stage Research Projects
Generation of expandable, self-renewing muscle stem cells for Duchenne Muscular Dystrophy
$252,000
University of California, San Francisco
Sonja Schrepfer
Inception – Discovery Stage Research Projects
Hypo-immunogenic cardiac patches for myocardial regeneration
$235,818
University of Southern California
Biju B. Thomas
Inception – Discovery Stage Research Projects
A Novel Tissue Engineering Technique to Repair Degenerated Retina
$215,133
Children’s Hospital of Los Angeles
Dr. Senta Georgia
Inception – Discovery Stage Research Projects
Developing a personalized approach to beta cell replacement for patients with a genetic form of diabetes
$179,995
Vitalant Research Institute
Dr. Marcus Oliver Muench
Inception – Discovery Stage Research Projects
Modulating Liver Sinusoidal Endothelial Cell Permeability to Enhance Engraftment of Endothelial Cell Progenitors for the Treatment of Hemophilia A
$180,000
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