Active Awards Portfolio Dashboard

It takes a lot of effort to develop a promising stem cell research idea into an effective treatment that can help patients. CIRM funds a pipeline of projects spanning discovery, translation and clinical stage research. Check out our portfolio of active research awards in our interactive dashboard below. For a detailed list of CIRM-funded clinical trials, visit our Clinical Trials Dashboard.

Disease	Cell Type	Therapeutic or Technology	Institution	Stage	Project Objective	Details
Amyotrophic Lateral Sclerosis, Neurological Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	Cedars-Sinai		Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer, Cancer, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	COH		Clinical Trial, Phase 1 or Phase 1/2
HIV/AIDS, Immune Disease, Infectious Disease	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSF		Clinical Trial, Phase 1 or Phase 1/2
Neurological Disorders, Parkinson's Disease	Vital Research Opportunity	Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	Brain Neurotherapy Bio		Clinical Trial, Phase 1 or Phase 1/2
Corneal Damage, Vision Loss	Adult or Tissue Stem Cell	Personalized cell therapy, Therapeutic Approach	UCLA		Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa, Vision Loss	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	Cedars-Sinai		Clinical Trial, Phase 1 or Phase 1/2
Brain Cancer, Breast Cancer, Cancer, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	COH		Clinical Trial, Phase 1 or Phase 1/2
Cystinosis, Kidney Disease, Kidney Failure, Metabolic Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSD		Clinical Trial, Phase 1 or Phase 1/2
Diabetes, Metabolic Disorders, Type 1 diabetes	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	UCSF		Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders, Severe Combined Immunodeficiency, X-linked (X-SCID)	Adult or Tissue Stem Cell	Antibody, Biologic, Therapeutic Approach	Jasper Therapeutics, Inc.		Clinical Trial, Phase 1 or Phase 1/2
Kidney Disease, Kidney Failure	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	Stanford		Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders, Sickle Cell Disease	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	COH		Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders, Severe Combined Immunodeficiency, Artemis deficient (ART-SCID)	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSF		Clinical Trial, Phase 1 or Phase 1/2
Cancer, Lung Cancer, Solid Tumors	Adult or Tissue Stem Cell	Antibody, Biologic, Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCLA		Clinical Trial, Phase 1 or Phase 1/2
Kidney Disease, Kidney Failure	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	Medeor Acquisition Corp.		Clinical Trial, Phase 3
Blood Cancer, Blood Disorders, Bone Marrow Transplant and Viral Infection, Cancer	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	CHLA		Clinical Trial, Phase 1 or Phase 1/2
Retinitis Pigmentosa, Vision Loss	Other	Donor cell therapy, Therapeutic Approach	jCyte		Clinical Trial, Phase 2
Kidney Disease, Kidney Failure	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	Stanford		Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders, Genetic Disorder, Immune Disease, Pediatrics, Severe Combined Immunodeficiency, Adenosine deaminase-deficient (ADA-SCID)	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCLA		Clinical Trial, Phase 2
Alpha Thalassemia Major, Blood Disorders	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	UCSF		Clinical Trial, Phase 1 or Phase 1/2
Blood Cancer, Cancer, HIV-related Lymphoma, HIV/AIDS, Infectious Disease	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UC Davis		Clinical Trial, Phase 1 or Phase 1/2
Blood Disorders, Immune Disease, Pediatrics, X-linked Chronic Granulomatous Disease	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCLA		Clinical Trial, Phase 1 or Phase 1/2
Heart Disease		Gene Therapy (All), Gene Therapy, cell free, Therapeutic Approach	Rejuvenate Bio		IND
Neurological Disorders, Spinal Cord Injury	Embryonic Stem Cell	Donor cell therapy, Therapeutic Approach	UCSD		IND
Heart Disease, Heart failure		Antibody, Biologic, Therapeutic Approach	UCLA		IND
Cancer, Sarcoma, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	CHLA		IND
Blood Cancer, Cancer, Multiple Myeloma	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSF		IND
Developmental Disorders, Genetic Disorder, Neurological Disorders, Pediatrics		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	Elpida Therapeutics		IND
Heart Disease, Heart failure	Adult or Tissue Stem Cell, Somatic Cell	Biologic, Exosomes based therapy, Therapeutic Approach	Cedars-Sinai		IND
Cancer, Ovarian Cancer, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	COH		IND
Blood Disorders, Bone Marrow Transplant and Viral Infection	Somatic Cell	Biologic, Gene modification, Gene Therapy (All), Gene-modified, donor cell therapy, Therapeutic Approach	Tr1X Inc.		Clinical Trial, Phase 1 or Phase 1/2
Epilepsy, Intellectual Disability, Neurological Disorders		Gene Therapy (All), Gene Therapy, cell free, Nucleic acid based therapy, Therapeutic Approach	Mahzi Therapeutics		IND
Blood Disorders, Sickle Cell Disease	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UC Davis		IND
Cystic Fibrosis, Respiratory Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Stanford		IND
Bone or Cartilage Disease, Cartilage defect	Somatic Cell	Donor cell therapy, Therapeutic Approach	UC Irvine		IND
Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML)		Small molecule therapy, Therapeutic Approach	Aspera Biomedicines, Inc.		IND
Age-related macular degeneration, Vision Loss	iPS Cell	Personalized cell therapy, Therapeutic Approach	UCLA		IND
Neurological Disorders, Parkinson's Disease	iPS Cell	Donor cell therapy, Therapeutic Approach	Kenai Therapeutics		IND
Genetic Disorder, Metabolic Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Rampart Bioscience		IND
B cell cancers, Blood Cancer, Cancer, Solid Tumors	Cancer Stem Cell	Biologic, Protein/peptide therapy, Therapeutic Approach	Nammi Therapeutics, Inc.		IND
Breast Cancer, Cancer, Melanoma, Solid Tumors	Somatic Cell	Donor cell therapy, Therapeutic Approach	Calidi Biotherapeutics, Inc.		IND
Immune Disease	Adult or Tissue Stem Cell	Donor cell therapy, Therapeutic Approach	Ossium Health, Inc.		IND
Neurological Disorders	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Personalized cell therapy, Therapeutic Approach	UC Davis		IND
Genetic Disorder, Metabolic Disorders, Neurological Disorders, Pediatrics	Somatic Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	Stanford		IND
Blood Cancer, Cancer, Leukemia, Acute Myeloid (AML)	Cancer Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSF		IND
Blood Disorders, X-linked Chronic Granulomatous Disease	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	ImmunoVec		Clinical Trial, Phase 1 or Phase 1/2
Skin Disease, Wounds, ulcers		Small molecule therapy, Therapeutic Approach	UCLA		IND
Bone or Cartilage Disease, Cartilage defect	Embryonic Stem Cell	Donor cell therapy, Therapeutic Approach	USC		IND
Blood Cancer, Cancer	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	UCSD		IND
Brain Cancer, Cancer, Solid Tumors	Adult or Tissue Stem Cell	Gene Therapy (All), Gene-modified, personalized cell therapy, Therapeutic Approach	COH		IND