Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium. 2013 Proc Natl Acad Sci U S A
A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. 2013 Cancer Discov
Mapping human epigenomes. 2013 Cell
Abnormal calcium handling properties underlie familial hypertrophic cardiomyopathy pathology in patient-specific induced pluripotent stem cells. 2013 Cell Stem Cell
Insulin and IGFs Enhance Hepatocyte Differentiation from Human Embryonic Stem Cells via the PI3K/AKT Pathway. 2013 Stem Cells
The interactomes of POU5F1 and SOX2 enhancers in human embryonic stem cells. 2013 Sci Rep
Augmenting endogenous Wnt signaling improves skin wound healing. 2013 PLoS One
The Presenilin-1 DeltaE9 Mutation Results in Reduced gamma-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells. 2013 Cell Rep
Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. 2013 Stem Cell Res Ther
Quantitative Transcriptomics using Designed Primer-based Amplification. 2013 Sci Rep
A High-Resolution Enhancer Atlas of the Developing Telencephalon. 2013 Cell
mir-17-92: a polycistronic oncomir with pleiotropic functions. 2013 Immunol Rev
Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. 2013 PLoS One
Intraspinal transplantation of mouse and human neural precursor cells. 2013 Curr Protoc Stem Cell Biol
ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement. 2013 PLoS One
Tissue Engineering the Small Intestine. 2013 Clin Gastroenterol Hepatol
Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling. 2013 Science
Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? 2013 Stem Cell Reports
Mesenchymal stem cells inhibit multiple myeloma cells via the Fas/Fas ligand pathway. 2013 Stem Cell Res Ther
Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment. 2013 Proc Natl Acad Sci U S A
Opposing chemokine gradients control human thymocyte migration in situ. 2013 J Clin Invest
Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst. 2013 Dev Cell
Cerebellar Cortical Lamination and Foliation Require Cyclin A2. 2013 Dev Biol
Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca(2)(+)/calmodulin-dependent protein kinase II. 2013 Mol Cancer Ther
Call for fellowship programs in stem cell-based regenerative and cellular medicine: new stem cell training is essential for physicians. 2013 Regen Med
Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development. 2013 Proc Natl Acad Sci U S A
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. 2013 Cell
FOXO3 Shares Common Targets with ASCL1 Genome-wide and Inhibits ASCL1-Dependent Neurogenesis. 2013 Cell Rep
Perivascular support of human hematopoietic stem/progenitor cells. 2013 Blood
Allelic Exclusion and Peripheral Reconstitution by TCR Transgenic T Cells Arising From Transduced Human Hematopoietic Stem/Progenitor Cells. 2013 Mol Ther
MK5 activates Rag transcription via Foxo1 in developing B cells. 2013 J Exp Med
DICE, an efficient system for iterative genomic editing in human pluripotent stem cells. 2013 Nucleic Acids Res
Wnt7a regulates multiple steps of neurogenesis. 2013 Mol Cell Biol
Endothelial cells derived from embryonic stem cells respond to cues from topographical surface patterns. 2013 J Biol Eng
Modulation of beta-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal. 2013 Nat Commun
Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development. 2013 Epigenetics Chromatin
Modification of hematopoietic stem/progenitor cells with CD19-specific chimeric antigen receptors as a novel approach for cancer immunotherapy. 2013 Hum Gene Ther
Intrachromosomal Looping Is Required for Activation of Endogenous Pluripotency Genes during Reprogramming. 2013 Cell Stem Cell
Ossifying Fibroma Tumor Stem Cells Are Maintained by Epigenetic Regulation of a TSP1/TGF-beta/SMAD3 Autocrine Loop. 2013 Cell Stem Cell
Ebf1 and c-Myb repress rag transcription downstream of Stat5 during early B cell development. 2013 J Immunol
The viral oncogene Np9 acts as a critical molecular switch for co-activating beta-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells. 2013 Leukemia
Wnt signaling regulates pulp volume and dentin thickness. 2013 J Bone Miner Res
Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA. 2013 Genes Dev
Patient-specific stem cells and cardiovascular drug discovery. 2013 JAMA
Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. 2013 Proc Natl Acad Sci U S A
Fezf2 expression identifies a multipotent progenitor for neocortical projection neurons, astrocytes, and oligodendrocytes. 2013 Neuron
Amyloid beta peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Abeta mediated toxicity in vitro. 2013 Biol Chem
Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice. 2013 J Infect Dis
Specialized tip/stalk-like and phalanx-like endothelial cells from embryonic stem cells. 2013 Stem Cells Dev
Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1. 2013 EMBO J


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