Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Modification of hematopoietic stem/progenitor cells with CD19-specific chimeric antigen receptors as a novel approach for cancer immunotherapy. 2013 Hum Gene Ther
Hypoxia and trophoblast differentiation: a key role for PPARgamma 2013 Stem Cells Dev
Introduction of Exogenous T-cell Receptors Into Human Hematopoietic Progenitors Results in Exclusion of Endogenous T-cell Receptor Expression. 2013 Mol Ther
Regulation of Mammalian Gene Dosage by Long Noncoding RNAs. 2013 Biomolecules
Projection reconstruction magnetic particle imaging. 2013 IEEE Trans Med Imaging
Ossifying Fibroma Tumor Stem Cells Are Maintained by Epigenetic Regulation of a TSP1/TGF-beta/SMAD3 Autocrine Loop. 2013 Cell Stem Cell
Ebf1 and c-Myb repress rag transcription downstream of Stat5 during early B cell development. 2013 J Immunol
The viral oncogene Np9 acts as a critical molecular switch for co-activating beta-catenin, ERK, Akt and Notch1 and promoting the growth of human leukemia stem/progenitor cells. 2013 Leukemia
Wnt signaling regulates pulp volume and dentin thickness. 2013 J Bone Miner Res
Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA. 2013 Genes Dev
Patient-specific stem cells and cardiovascular drug discovery. 2013 JAMA
Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. 2013 Proc Natl Acad Sci U S A
Fezf2 expression identifies a multipotent progenitor for neocortical projection neurons, astrocytes, and oligodendrocytes. 2013 Neuron
Amyloid beta peptide cleavage by kallikrein 7 attenuates fibril growth and rescues neurons from Abeta mediated toxicity in vitro. 2013 Biol Chem
Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice. 2013 J Infect Dis
Specialized tip/stalk-like and phalanx-like endothelial cells from embryonic stem cells. 2013 Stem Cells Dev
Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1. 2013 EMBO J
Breaking down protein degradation mechanisms in cardiac muscle. 2013 Trends Mol Med
Deficiency of MIWI2 (Piwil4) induces mouse erythroleukemia cell differentiation, but has no effect on hematopoiesis in vivo. 2013 PLoS One
Identification of Human Embryonic Progenitor Cell Targeting Peptides Using Phage Display. 2013 PLoS One
beta-globin gene transfer to human bone marrow for sickle cell disease. 2013 J Clin Invest
Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models. 2013 PLoS One
An indirect approach to generating specific human cell types. 2013 Nat Methods
Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells. 2013 Proc Natl Acad Sci U S A
Encodes Two Isoforms with Distinct Functions in Cancers. 2013 PLoS One
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism. 2013 Cell Res
Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation. 2013 Proc Natl Acad Sci U S A
Tissue engineering: a promising therapeutic approach to necrotizing enterocolitis. 2013 Semin Pediatr Surg
Understanding telomere diseases through analysis of patient-derived iPS cells. 2013 Curr Opin Genet Dev
Efficient Generation of Astrocytes From Human Pluripotent Stem Cells in Defined Conditions. 2013 Stem Cells
Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart. 2013 EMBO Mol Med
Modeling heart disease in a dish: From somatic cells to disease-relevant cardiomyocytes. 2013 Trends Cardiovasc Med
DNA methyltransferase-3-dependent nonrandom template segregation in differentiating embryonic stem cells. 2013 J Cell Biol
Endogenous electric currents might guide rostral migration of neuroblasts. 2013 EMBO Rep
A dynamic population of stromal cells contributes to the follicle stem cell niche in the Drosophila ovary. 2013 Development
Factors affecting the structure and maturation of human tissue engineered skeletal muscle. 2013 Biomaterials
Implications and limitations of cellular reprogramming for psychiatric drug development. 2013 Exp Mol Med
Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex. 2013 Nat Commun
Human trophoblast progenitors: where do they reside? 2013 Semin Reprod Med
Contextual effect of repression of bone morphogenetic protein activity in prostate cancer. 2013 Endocr Relat Cancer
Transdifferentiation and remodeling of post-embryonic C. elegans cells by a single transcription factor. 2013 Development
Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo. 2013 J Virol
Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. 2013 Stem Cell Res
MicroRNA let-7d regulates the TLX/microRNA-9 cascade to control neural cell fate and neurogenesis. 2013 Sci Rep
Fgf10 overexpression enhances the formation of tissue-engineered small intestine. 2013 J Tissue Eng Regen Med
Back to the future: how human induced pluripotent stem cells will transform regenerative medicine. 2013 Hum Mol Genet
Combinatorial RNA-based gene therapy for the treatment of HIV/AIDS. 2013 Expert Opin Biol Ther
BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint. 2013 Nat Med
Genomic Analysis of hESC Pedigrees Identifies De Novo Mutations and Enables Determination of the Timing and Origin of Mutational Events. 2013 Cell Rep
Histone Acetylation Regulates Intracellular pH. 2013 Mol Cell


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