Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. 2014 Sci Transl Med
Critical roles of a small conductance Ca2+-activated K+ channel (SK3) in the repolarization process of atrial myocytes. 2014 Cardiovasc Res
Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors. 2014 Cell Rep
Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules. 2014 Hum Mol Genet
Clinical use of proteasome inhibitors in the treatment of multiple myeloma. 2014 Pharmaceuticals (Basel)
Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway. 2014 Cell Rep
Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile x syndrome in a mouse model. 2014 J Neurosci
Hypoxia-Inducible Factor (HIF)/Vascular Endothelial Growth Factor (VEGF) Signaling in the Retina. 2014 Adv Exp Med Biol
Differentiation of pluripotent stem cells into retinal pigmented epithelium. 2014 Dev Ophthalmol
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. 2014 Proc Natl Acad Sci U S A
Human limbal mesenchymal cells support the growth of human corneal epithelial stem/progenitor cells. 2014 Invest Ophthalmol Vis Sci
Human Neural Stem Cells Survive Long Term in the Midbrain of Dopamine-Depleted Monkeys After GDNF Overexpression and Project Neurites Toward an Appropriate Target. 2014 Stem Cells Transl Med
Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia. 2014 Stem Cell Reports
Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development. 2014 J Dent Res
Neonatal immune-tolerance in mice does not prevent xenograft rejection. 2014 Exp Neurol
Human Lymphoid Development in the Absence of Common gamma-Chain Receptor Signaling. 2014 J Immunol
Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns. 2014 Proc Natl Acad Sci U S A
Sexually dimorphic effect of in vitro fertilization (IVF) on adult mouse fat and liver metabolomes. 2014 Endocrinology
Cell-specific translational profiling in acute kidney injury. 2014 J Clin Invest
Utilizing Stem Cell-Derived RPE Cells as A Therapeutic Intervention for Age-Related Macular Degeneration. 2014 Adv Exp Med Biol
Modular plasmonic nanocarriers for efficient and targeted delivery of cancer-therapeutic siRNA. 2014 Nano Lett
Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1. 2014 Stem Cell Reports
Enhancer-trap Flippase Lines for Clonal Analysis in the Drosophila Ovary. 2014 G3 (Bethesda)
Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming. 2014 Cell Stem Cell
Cardiospheres reverse adverse remodeling in chronic rat myocardial infarction: roles of soluble endoglin and Tgf-beta signaling. 2014 Basic Res Cardiol
STAT3 Phosphorylation at Tyrosine 705 and Serine 727 Differentially Regulates Mouse ESC Fates. 2014 Stem Cells
Endogenous WNT Signaling Regulates hPSC-Derived Neural Progenitor Cell Heterogeneity and Specifies Their Regional Identity. 2014 Stem Cell Reports
Ptch2 mediates the Shh response in Ptch1-/- cells. 2014 Development
Discovery of consensus gene signature and intermodular connectivity defining self-renewal of human embryonic stem cells. 2014 Stem Cells
miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110. 2014 Nature
The past, present and future of stem cell clinical trials for ALS. 2014 Exp Neurol
Translational Profiles of Medullary Myofibroblasts during Kidney Fibrosis. 2014 J Am Soc Nephrol
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. 2014 Nat Med
Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells. 2014 Stem Cells
Cartilage Tissue Engineering Using Dermis Isolated Adult Stem Cells: The Use of Hypoxia during Expansion versus Chondrogenic Differentiation. 2014 PLoS One
Single-molecule super-resolution light-sheet microscopy. 2014 Chemphyschem
Evidence against a Stem Cell Origin of New Hepatocytes in a Common Mouse Model of Chronic Liver Injury. 2014 Cell Rep
Inhibitory Interneuron Progenitor Transplantation Restores Normal Learning and Memory in ApoE4 Knock-In Mice without or with Abeta Accumulation. 2014 J Neurosci
Recombinase-Mediated Reprogramming and Dystrophin Gene Addition in mdx Mouse Induced Pluripotent Stem Cells. 2014 PLoS One
COE Loss-of-Function Analysis Reveals a Genetic Program Underlying Maintenance and Regeneration of the Nervous System in Planarians. 2014 PLoS Genet
Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform. 2014 Circ Res
Shaking up the salt and pepper: origins of cellular heterogeneity in the inner cell mass of the blastocyst. 2014 EMBO J
Tracking migration during human T cell development. 2014 Cell Mol Life Sci
Moving beyond surrogate endpoints in cell therapy trials for heart disease. 2014 Stem Cells Transl Med
A Rare Human Syndrome Provides Genetic Evidence that WNT Signaling Is Required for Reprogramming of Fibroblasts to Induced Pluripotent Stem Cells. 2014 Cell Rep
Engineering strategies to mimic the glioblastoma microenvironment. 2014 Adv Drug Deliv Rev
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. 2014 Proc Natl Acad Sci U S A
Follistatin interacts with Noggin in the development of the axial skeleton. 2014 Mech Dev
Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. 2014 Cell Stem Cell
Human neural progenitor cells generated from induced pluripotent stem cells can survive, migrate, and integrate in the rodent spinal cord. 2014 J Comp Neurol

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