Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
[(18)F]FDG-PET and [(18)F]MPPF-PET are brain biomarkers for the creatine transporter Slc6a8 loss of function mutation. 2025 Sci Rep
A Living Organoid Biobank of Crohn’s Disease Patients Reveals Distinct Clinical Correlates of Molecular Disease Subtypes. 2025 medRxiv
A Rare Hematopoietic Stem Cell-Derived Megakaryocyte Progenitor Accumulates via Enhanced Survival and Contributes to Exacerbated Thrombopoiesis Upon Aging. 2025 Aging Cell
A simple approach of nuclei isolation for single nucleus multiome sequencing. 2025 J Mol Cell Cardiol
A single-cell and spatial genomics atlas of human skin fibroblasts reveals shared disease-related fibroblast subtypes across tissues. 2025 Nat Immunol
Acholinebio-ionicliquid-functionalized gelatin methacryloyl hydrogel for chronic wound healing 2025 European Polymer Journal
Active telomere elongation by a subclass of cancer-associated POT1 mutations. 2025 Genes Dev
Adipose tissue ageing: implications for metabolic health and lifespan. 2025 Nat Rev Endocrinol
ADMET-AI Enables Interpretable Predictions of Drug-Induced Cardiotoxicity. 2025 Circulation
Advances in carbon nanomaterials and their polymeric composites in neural tissue engineering. 2025 Adv Drug Deliv Rev
Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies. 2025 Nat Commun
An SSTR2-somatostatin chemotactic axis drives T cell progenitor homing to the intestines. 2025 Nat Immunol
Androgenetic alopecia. 2025 Nat Rev Dis Primers
Biological tendon regeneration, are we almost there or is it still a stretch? 2025 Regen Med
CAR macrophages with built-In CD47 blocker combat tumor antigen heterogeneity and activate T cells via cross-presentation. 2025 Nat Commun
Challenging Reward Structures and Organizational Cultures that Propagate Stem Cell Hyperbole. 2025 Stem Cell Rev Rep
Complementary biomolecular coassemblies direct energy transport for cardiac photostimulators. 2025 Proc Natl Acad Sci U S A
Composition and RNA binding specificity of metazoan RNase MRP. 2025 Nucleic Acids Res
Controllable Doping for Tunable and Multimodal Emission in ZnS-Based Mechanoluminescent Nanocrystals. 2025 Nano Lett
Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork. 2025 Transl Vis Sci Technol
Culture conditions differentially regulate the inflammatory niche and cellular phenotype of tracheobronchial basal stem cells. 2025 Am J Physiol Lung Cell Mol Physiol
Derivation and Characterization of Isogenic OPA1 Mutant and Control Human Pluripotent Stem Cell Lines. 2025 Cells
Designing and Evaluating Circadian Experiments on Mouse Skin. 2025 J Invest Dermatol
Developing machine learning-driven multidisease diagnostic platforms using immune repertoire sequencing. 2025 Am J Transplant
Distinct adipose progenitor cells emerging with age drive active adipogenesis. 2025 Science
Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics. 2025 Neuron
Dosing parameters for grafting human neural stem cells into sites of spinal cord injury. 2025 Exp Neurol
Double-strand break repair pathways differentially affect processing and transduction by dual AAV vectors. 2025 Nat Commun
Dual alpha-globin-truncated erythropoietin receptor knockin restores hemoglobin production in alpha-thalassemia-derived erythroid cells. 2025 Cell Rep
Effect of immunosuppression on hESC-derived retina organoids in vitro and in vivo. 2025 Stem Cell Res Ther
Effects of PDMS culture on stem cell differentiation towards definitive endoderm and hepatocytes. 2025 Acta Biomater
Efficient Retroviral Transduction and Competitive Homing for Investigating GPCR-Mediated T-Cell Localization in Diverse Tissue Microenvironments. 2025 J Vis Exp
eIF3 engages with 3′-UTR termini of highly translated mRNAs. 2025 Elife
Elevated Senescence Markers in Developing Trisomy 21 Human Lungs. 2025 Am J Respir Cell Mol Biol
Engineering synthetic signaling receptors to enable erythropoietin-free erythropoiesis. 2025 Nat Commun
Enhanced neuromorphogenesis of neural stem cells via the optimization of physical stimulus-responsive signaling pathways. 2025 Stem Cell Res Ther
Epigenetic Upregulation of Carotid Body Angiotensin Signaling Increases Blood Pressure. 2025 Hypertension
Every cell every gene all at once: Systems genetic approaches toward corticogenesis. 2025 Curr Opin Neurobiol
Evidence of neuronal DNA damage in the brains of patients with Rett syndrome. 2025 Dis Model Mech
Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors. 2025 Cancer Discov
F.O.R.W.A.R.D: A Data-Driven Framework for Network-Based Target Prioritization in Drug Discovery. 2025 bioRxiv
Functional Neurogenomics to Dissect Disease Mechanisms Across Models. 2025 Annu Rev Genomics Hum Genet
FXYD2 marks and regulates maturity of beta cells via ion channel-mediated signal transduction. 2025 Nat Commun
Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. 2025 Nat Protoc
Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines. 2025 Stem Cell Res
Genome editing with programmable base editors in human cells. 2025 Methods Enzymol
Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate. 2025 Genes Dev
Identification of CD84 as a potent survival factor in acute myeloid leukemia. 2025 J Clin Invest
Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. 2025 NPJ Precis Oncol
IgG autoantibodies in bullous pemphigoid induce a pathogenic MyD88-dependent pro-inflammatory response in keratinocytes. 2025 Nat Commun
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