Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform. 2014 Circ Res
Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile x syndrome in a mouse model. 2014 J Neurosci
Engineering strategies to mimic the glioblastoma microenvironment. 2014 Adv Drug Deliv Rev
Differentiation of pluripotent stem cells into retinal pigmented epithelium. 2014 Dev Ophthalmol
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. 2014 Proc Natl Acad Sci U S A
Phenotypic differences in hiPSC NPCs derived from patients with schizophrenia. 2014 Mol Psychiatry
Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming. 2014 Mol Cell
Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. 2014 EMBO Mol Med
Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns. 2014 Proc Natl Acad Sci U S A
Cell-specific translational profiling in acute kidney injury. 2014 J Clin Invest
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem-Derived Cardiomyocytes Cultured over Different Spatial Scales. 2014 Tissue Eng Part C Methods
Modular plasmonic nanocarriers for efficient and targeted delivery of cancer-therapeutic siRNA. 2014 Nano Lett
Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis. 2014 Cell Rep
Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia. 2014 Stem Cell Reports
Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones. 2014 Cell Stem Cell
TACE in perinatal mouse lung epithelial cells promotes lung saccular formation. 2013 Am J Physiol Lung Cell Mol Physiol
Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer. 2013 BMC Biol
Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state. 2013 Stem Cell Reports
Lysophosphatidic acid enhances stromal cell-directed angiogenesis. 2013 PLoS One
Mesenchymal stem cells inhibit multiple myeloma cells via the Fas/Fas ligand pathway. 2013 Stem Cell Res Ther
Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment. 2013 Proc Natl Acad Sci U S A
Opposing chemokine gradients control human thymocyte migration in situ. 2013 J Clin Invest
Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst. 2013 Dev Cell
Insulin and IGFs Enhance Hepatocyte Differentiation from Human Embryonic Stem Cells via the PI3K/AKT Pathway. 2013 Stem Cells
The interactomes of POU5F1 and SOX2 enhancers in human embryonic stem cells. 2013 Sci Rep
Augmenting endogenous Wnt signaling improves skin wound healing. 2013 PLoS One
The Presenilin-1 DeltaE9 Mutation Results in Reduced gamma-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells. 2013 Cell Rep
Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. 2013 Stem Cell Res Ther
Quantitative Transcriptomics using Designed Primer-based Amplification. 2013 Sci Rep
A High-Resolution Enhancer Atlas of the Developing Telencephalon. 2013 Cell
mir-17-92: a polycistronic oncomir with pleiotropic functions. 2013 Immunol Rev
Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. 2013 PLoS One
Intraspinal transplantation of mouse and human neural precursor cells. 2013 Curr Protoc Stem Cell Biol
ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement. 2013 PLoS One
Tissue Engineering the Small Intestine. 2013 Clin Gastroenterol Hepatol
Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling. 2013 Science
Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? 2013 Stem Cell Reports
Endogenous mammalian histone H3.3 exhibits chromatin-related functions during development. 2013 Epigenetics Chromatin
Modification of hematopoietic stem/progenitor cells with CD19-specific chimeric antigen receptors as a novel approach for cancer immunotherapy. 2013 Hum Gene Ther
Intrachromosomal Looping Is Required for Activation of Endogenous Pluripotency Genes during Reprogramming. 2013 Cell Stem Cell
Cerebellar Cortical Lamination and Foliation Require Cyclin A2. 2013 Dev Biol
Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca(2)(+)/calmodulin-dependent protein kinase II. 2013 Mol Cancer Ther
Call for fellowship programs in stem cell-based regenerative and cellular medicine: new stem cell training is essential for physicians. 2013 Regen Med
Brg1 governs distinct pathways to direct multiple aspects of mammalian neural crest cell development. 2013 Proc Natl Acad Sci U S A
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. 2013 Cell
FOXO3 Shares Common Targets with ASCL1 Genome-wide and Inhibits ASCL1-Dependent Neurogenesis. 2013 Cell Rep
Perivascular support of human hematopoietic stem/progenitor cells. 2013 Blood
Allelic Exclusion and Peripheral Reconstitution by TCR Transgenic T Cells Arising From Transduced Human Hematopoietic Stem/Progenitor Cells. 2013 Mol Ther
MK5 activates Rag transcription via Foxo1 in developing B cells. 2013 J Exp Med
DICE, an efficient system for iterative genomic editing in human pluripotent stem cells. 2013 Nucleic Acids Res


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