Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Human induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. 2014 Hum Mol Genet
Wnt signaling regulates homeostasis of the periodontal ligament. 2014 J Periodontal Res
Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed States of human pluripotent stem cells. 2014 Stem Cell Reports
Reorganization of enhancer patterns in transition from naive to primed pluripotency. 2014 Cell Stem Cell
Targeted delivery of mesenchymal stem cells to the bone. 2014 Bone
Tbr2 is required to generate a neural circuit mediating the pupillary light reflex. 2014 J Neurosci
X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. 2014 Cell
A systems biology approach for defining the molecular framework of the hematopoietic stem cell niche. 2014 Cell Stem Cell
Actin and dynamin2 dynamics and interplay during clathrin-mediated endocytosis. 2014 J Cell Biol
Technical Variations in Low-Input RNA-seq Methodologies. 2014 Sci Rep
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. 2014 Immunity
Engineering the human thymic microenvironment to support thymopoiesis in vivo. 2014 Stem Cells
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. 2014 Nat Med
Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. 2014 Development
Fate of iPSCs Derived from Azoospermic and Fertile Men following Xenotransplantation to Murine Seminiferous Tubules. 2014 Cell Rep
Isolation, culture, and imaging of human fetal pancreatic cell clusters. 2014 J Vis Exp
Mouse liver repopulation with hepatocytes generated from human fibroblasts. 2014 Nature
Replication of Mycobacterium tuberculosis in retinal pigment epithelium. 2014 JAMA Ophthalmol
Serine integrase chimeras with activity in E. coli and HeLa cells. 2014 Biol Open
Hypoxia-Inducible Factor (HIF)/Vascular Endothelial Growth Factor (VEGF) Signaling in the Retina. 2014 Adv Exp Med Biol
Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model. 2014 Proc Natl Acad Sci U S A
Pharmacological induction of pancreatic islet cell transdifferentiation: relevance to type I diabetes. 2014 Cell Death Dis
Biomaterial microenvironments to support the generation of new neurons in the adult brain. 2014 Stem Cells
Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis 2014 Aging
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. 2014 Mol Psychiatry
LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction. 2014 Neurobiol Dis
Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. 2014 Nature
Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. 2014 Stem Cells
Critical roles of a small conductance Ca2+-activated K+ channel (SK3) in the repolarization process of atrial myocytes. 2014 Cardiovasc Res
Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules. 2014 Hum Mol Genet
sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveal differentially expressed microRNAs and novel isomiRs with distinct targets. 2014 Stem Cells
Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway. 2014 Cell Rep
Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. 2014 J Neurosci
Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. 2014 Proc Natl Acad Sci U S A
Utilizing Stem Cell-Derived RPE Cells as A Therapeutic Intervention for Age-Related Macular Degeneration. 2014 Adv Exp Med Biol
Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. 2014 Cancer Prev Res (Phila)
An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons. 2014 Nature
Human Neural Stem Cells Survive Long Term in the Midbrain of Dopamine-Depleted Monkeys After GDNF Overexpression and Project Neurites Toward an Appropriate Target. 2014 Stem Cells Transl Med
HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice. 2014 Cancer Res
Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development. 2014 J Dent Res
Neonatal immune-tolerance in mice does not prevent xenograft rejection. 2014 Exp Neurol
HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. 2014 PLoS Genet
Human Lymphoid Development in the Absence of Common gamma-Chain Receptor Signaling. 2014 J Immunol
A long noncoding RNA protects the heart from pathological hypertrophy. 2014 Nature
Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis. 2014 Stem Cell Reports
Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant. 2014 Mol Ther
Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells. 2014 J Vis Exp
Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. 2014 Nat Commun
Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. 2014 Nature
Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming. 2014 Cell Stem Cell

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