Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile x syndrome in a mouse model. 2014 J Neurosci
Mouse SCNT ESCs Have Lower Somatic Mutation Load Than Syngeneic iPSCs. 2014 Stem Cell Reports
Engineering strategies to mimic the glioblastoma microenvironment. 2014 Adv Drug Deliv Rev
Differentiation of pluripotent stem cells into retinal pigmented epithelium. 2014 Dev Ophthalmol
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. 2014 Proc Natl Acad Sci U S A
Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia. 2014 Stem Cell Reports
Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones. 2014 Cell Stem Cell
Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns. 2014 Proc Natl Acad Sci U S A
Cell-specific translational profiling in acute kidney injury. 2014 J Clin Invest
Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression. 2014 EMBO Mol Med
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem-Derived Cardiomyocytes Cultured over Different Spatial Scales. 2014 Tissue Eng Part C Methods
Modular plasmonic nanocarriers for efficient and targeted delivery of cancer-therapeutic siRNA. 2014 Nano Lett
Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis. 2014 Cell Rep
TACE in perinatal mouse lung epithelial cells promotes lung saccular formation. 2013 Am J Physiol Lung Cell Mol Physiol
Spatial-temporal targeting of lung-specific mesenchyme by a Tbx4 enhancer. 2013 BMC Biol
Direct reprogramming of human fibroblasts toward a cardiomyocyte-like state. 2013 Stem Cell Reports
Lysophosphatidic acid enhances stromal cell-directed angiogenesis. 2013 PLoS One
Insulin and IGFs Enhance Hepatocyte Differentiation from Human Embryonic Stem Cells via the PI3K/AKT Pathway. 2013 Stem Cells
Fending for a Braveheart. 2013 EMBO J
Augmenting endogenous Wnt signaling improves skin wound healing. 2013 PLoS One
The Presenilin-1 DeltaE9 Mutation Results in Reduced gamma-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells. 2013 Cell Rep
Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. 2013 Stem Cell Res Ther
Opposing chemokine gradients control human thymocyte migration in situ. 2013 J Clin Invest
Lineage tracing with Axin2 reveals distinct developmental and adult populations of Wnt/beta-catenin-responsive neural stem cells. 2013 Proc Natl Acad Sci U S A
Radially Branched Deployment for More Efficient Cell Transplantation at the Scale of the Human Brain. 2013 Stereotact Funct Neurosurg
mir-17-92: a polycistronic oncomir with pleiotropic functions. 2013 Immunol Rev
Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. 2013 PLoS One
ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement. 2013 PLoS One
Serotonergic 5-HT(1A) receptor agonist (8-OH-DPAT) ameliorates impaired micturition reflexes in a chronic ventral root avulsion model of incomplete cauda equina/conus medullaris injury. 2013 Exp Neurol
Interfollicular epidermal stem cells self-renew via autocrine Wnt signaling. 2013 Science
Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? 2013 Stem Cell Reports
Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2. 2013 Development
Mesenchymal stem cells inhibit multiple myeloma cells via the Fas/Fas ligand pathway. 2013 Stem Cell Res Ther
Hippo signaling disruption and Akt stimulation of ovarian follicles for infertility treatment. 2013 Proc Natl Acad Sci U S A
Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst. 2013 Dev Cell
Intraspinal transplantation of mouse and human neural precursor cells. 2013 Curr Protoc Stem Cell Biol
Cerebellar Cortical Lamination and Foliation Require Cyclin A2. 2013 Dev Biol
The Pluripotency Factor-Bound Intron 1 of Xist Is Dispensable for X Chromosome Inactivation and Reactivation In Vitro and In Vivo. 2013 Cell Rep
Berbamine inhibits the growth of liver cancer cells and cancer-initiating cells by targeting Ca(2)(+)/calmodulin-dependent protein kinase II. 2013 Mol Cancer Ther
Timothy syndrome is associated with activity-dependent dendritic retraction in rodent and human neurons. 2013 Nat Neurosci
Modification of hematopoietic stem/progenitor cells with CD19-specific chimeric antigen receptors as a novel approach for cancer immunotherapy. 2013 Hum Gene Ther
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons. 2013 Cell
FOXO3 Shares Common Targets with ASCL1 Genome-wide and Inhibits ASCL1-Dependent Neurogenesis. 2013 Cell Rep
Genomic Editing of the HIV-1 Coreceptor CCR5 in Adult Hematopoietic Stem and Progenitor Cells Using Zinc Finger Nucleases. 2013 Mol Ther
FOXO3A directs a protective autophagy program in haematopoietic stem cells. 2013 Nature
DICE, an efficient system for iterative genomic editing in human pluripotent stem cells. 2013 Nucleic Acids Res
Wnt7a regulates multiple steps of neurogenesis. 2013 Mol Cell Biol
Differential roles of TNFR1 and TNFR2 signaling in adult hippocampal neurogenesis. 2013 Brain Behav Immun
Endothelial cells derived from embryonic stem cells respond to cues from topographical surface patterns. 2013 J Biol Eng
Modulation of beta-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal. 2013 Nat Commun


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