Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. 2016 Sci Rep
Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy. 2016 Sci Transl Med
Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. 2016 Development
Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor. 2016 Cell
Design Principles for Engineering of Tissues from Human Pluripotent Stem Cells. 2016 Curr Stem Cell Rep
alphaE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development. 2016 Nat Commun
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells. 2016 Stem Cell Reports
Vascular Endothelial Growth Factor (VEGF) Bioavailability Regulates Angiogenesis and Intestinal Stem and Progenitor Cell Proliferation during Postnatal Small Intestinal Development. 2016 PLoS One
Increased Gs Signaling in Osteoblasts Reduces Bone Marrow and Whole-Body Adiposity in Male Mice. 2016 Endocrinology
Reversible Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Mouse Embryonic Stem Cells. 2016 Cell Rep
Non-invasive Chamber-Specific Identification of Cardiomyocytes in Differentiating Pluripotent Stem Cells. 2016 Stem Cell Reports
In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining. 2016 Nucleic Acids Res
Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. 2016 JCI Insight
Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA. 2016 Mol Cell
Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles. 2016 Circ Cardiovasc Imaging
TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice. 2016 Gastroenterology
Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration. 2016 Cell Rep
Magnetic Resonance Imaging of Iron Oxide-Labeled Human Embryonic Stem Cell-Derived Cardiac Progenitors. 2016 Stem Cells Transl Med
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis. 2016 JCI Insight
Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. 2016 Nat Commun
A new class of temporarily phenotypic enhancers identified by CRISPR/Cas9-mediated genetic screening. 2016 Genome Res
An Overview of Direct Somatic Reprogramming: The Ins and Outs of iPSCs. 2016 Int J Mol Sci
Sequestration of Vascular Endothelial Growth Factor (VEGF) Induces Late Restrictive Lung Disease. 2016 PLoS One
Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types. 2016 Cell
YAP Induces Human Naive Pluripotency. 2016 Cell Rep
The tumorigenic potential of pluripotent stem cells: What can we do to minimize it? 2016 Bioessays
Transcriptome Encyclopedia of Early Human Development. 2016 Cell
Precise Correction of Disease Mutations in Induced Pluripotent Stem Cells Derived From Patients With Limb Girdle Muscular Dystrophy. 2016 Mol Ther
Adult Stem Cell Therapy and Heart Failure, 2000 to 2016: A Systematic Review. 2016 JAMA Cardiol
Concise Review: Paracrine Functions of Vascular Niche Cells in Regulating Hematopoietic Stem Cell Fate. 2016 Stem Cells Transl Med
Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. 2016 Invest Ophthalmol Vis Sci
alphaB-Crystallin Regulates Subretinal Fibrosis by Modulation of Epithelial-Mesenchymal Transition. 2016 Am J Pathol
A ventral root avulsion injury model for neurogenic underactive bladder studies. 2016 Exp Neurol
Layered hydrogels accelerate iPSC-derived neuronal maturation and reveal migration defects caused by MeCP2 dysfunction. 2016 Proc Natl Acad Sci U S A
Tissue Mechanics Orchestrate Wnt-Dependent Human Embryonic Stem Cell Differentiation. 2016 Cell Stem Cell
Biological impact of xeno-free chemically defined cryopreservation medium on amniotic epithelial cells. 2016 Stem Cell Res Ther
Targeting Transcriptional and Epigenetic Reprogramming in Stromal Cells in Fibrosis and Cancer. 2016 Cold Spring Harb Symp Quant Biol
CRISPR Interference Efficiently Induces Specific and Reversible Gene Silencing in Human iPSCs. 2016 Cell Stem Cell
Human and Murine Tissue-Engineered Colon Exhibit Diverse Neuronal Subtypes and Can Be Populated by Enteric Nervous System Progenitor Cells When Donor Colon Is Aganglionic. 2016 Tissue Eng Part A
Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis. 2016 PLoS One
Naive Human Pluripotent Cells Feature a Methylation Landscape Devoid of Blastocyst or Germline Memory. 2016 Cell Stem Cell
TBP/TFIID-dependent activation of MyoD target genes in skeletal muscle cells. 2016 Elife
Programmable RNA Tracking in Live Cells with CRISPR/Cas9. 2016 Cell
Functional Impairment in Miro Degradation and Mitophagy Is a Shared Feature in Familial and Sporadic Parkinson's Disease. 2016 Cell Stem Cell
Mitochondria in human pluripotent stem cell apoptosis. 2016 Semin Cell Dev Biol
Potential Strategies to Address the Major Clinical Barriers Facing Stem Cell Regenerative Therapy for Cardiovascular Disease: A Review. 2016 JAMA Cardiol
Genome-wide association study and targeted metabolomics identifies sex-specific association of CPS1 with coronary artery disease. 2016 Nat Commun
A Molecular Profile of the Endothelial Cell Response to Ionizing Radiation. 2016 Radiat Res
p53 Regulates Progenitor Cell Quiescence and Differentiation in the Airway. 2016 Cell Rep
Mechanical Control of Epithelial-to-Mesenchymal Transitions in Development and Cancer. 2016 Annu Rev Cell Dev Biol

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