Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. 2014 Immunity
Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. 2014 Development
Nanomicelle formulation modifies the pharmacokinetic profiles and cardiac toxicity of daunorubicin. 2014 Nanomedicine (Lond)
Isolation, culture, and imaging of human fetal pancreatic cell clusters. 2014 J Vis Exp
Replication of Mycobacterium tuberculosis in retinal pigment epithelium. 2014 JAMA Ophthalmol
Interneurons from embryonic development to cell-based therapy. 2014 Science
Serine integrase chimeras with activity in E. coli and HeLa cells. 2014 Biol Open
Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model. 2014 Proc Natl Acad Sci U S A
Polyglutamine Disease Modeling: Epitope Based Screen for Homologous Recombination using CRISPR/Cas9 System. 2014 PLoS Curr
Efficient Endoderm Induction from Human Pluripotent Stem Cells by Logically Directing Signals Controlling Lineage Bifurcations. 2014 Cell Stem Cell
Pharmacological induction of pancreatic islet cell transdifferentiation: relevance to type I diabetes. 2014 Cell Death Dis
Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis 2014 Aging
Isolation of single-base genome-edited human iPS cells without antibiotic selection. 2014 Nat Methods
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. 2014 Mol Psychiatry
Comparison of Epigenetic Mediator Expression and Function in Mouse and Human Embryonic Blastomeres. 2014 Hum Mol Genet
A pre-clinical murine model of oral implant osseointegration. 2014 Bone
Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity. 2014 J Biol Chem
Induction of Human Embryonic and Induced Pluripotent Stem Cells Into Urothelium. 2014 Stem Cells Transl Med
sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveal differentially expressed microRNAs and novel isomiRs with distinct targets. 2014 Stem Cells
Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. 2014 J Neurosci
Cell Junctions in the Specialized Conduction System of the Heart. 2014 Cell Commun Adhes
Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. 2014 Proc Natl Acad Sci U S A
Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. 2014 Cancer Prev Res (Phila)
Crosstalk Between Adrenergic and Toll-Like Receptors in Human Mesenchymal Stem Cells and Keratinocytes: A Recipe for Impaired Wound Healing. 2014 Stem Cells Transl Med
Fetal Intervention Increases Maternal T Cell Awareness of the Foreign Conceptus and Can Lead to Immune-Mediated Fetal Demise. 2014 J Immunol
An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons. 2014 Nature
HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice. 2014 Cancer Res
Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions. 2014 J Comp Neurol
Inner ear hair cell-like cells from human embryonic stem cells. 2014 Stem Cells Dev
Human induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. 2014 Hum Mol Genet
Wnt signaling regulates homeostasis of the periodontal ligament. 2014 J Periodontal Res
HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. 2014 PLoS Genet
A long noncoding RNA protects the heart from pathological hypertrophy. 2014 Nature
Tbr2 is required to generate a neural circuit mediating the pupillary light reflex. 2014 J Neurosci
Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis. 2014 Stem Cell Reports
Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant. 2014 Mol Ther
Potential for Cell Therapy in Parkinson's Disease Using Genetically-Programmed Human Embryonic Stem Cell-Derived Neural Progenitor Cells. 2014 J Comp Neurol
Technical Variations in Low-Input RNA-seq Methodologies. 2014 Sci Rep
Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells. 2014 J Vis Exp
Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. 2014 Nat Commun
Engineering the human thymic microenvironment to support thymopoiesis in vivo. 2014 Stem Cells
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. 2014 Nat Med
Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. 2014 Nature
Fate of iPSCs Derived from Azoospermic and Fertile Men following Xenotransplantation to Murine Seminiferous Tubules. 2014 Cell Rep
Mouse liver repopulation with hepatocytes generated from human fibroblasts. 2014 Nature
m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. 2014 Cell Stem Cell
Enhanced Genetic Modification of Adult Growth Factor Mobilized Peripheral Blood Hematopoietic Stem and Progenitor Cells With Rapamycin. 2014 Stem Cells Transl Med
Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. 2014 Stem Cells Dev
Biomaterial microenvironments to support the generation of new neurons in the adult brain. 2014 Stem Cells
Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. 2014 Cell Rep


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