Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
A cGMP-applicable Expansion Method for Aggregates of Human Neural Stem and Progenitor Cells Derived From Pluripotent Stem Cells or Fetal Brain Tissue. 2014 J Vis Exp
Comparison of Epigenetic Mediator Expression and Function in Mouse and Human Embryonic Blastomeres. 2014 Hum Mol Genet
Wnt signaling regulates homeostasis of the periodontal ligament. 2014 J Periodontal Res
Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. 2014 Cell
Sphingosine phosphate lyase regulates myogenic differentiation via S1P receptor-mediated effects on myogenic microRNA expression. 2014 FASEB J
Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity. 2014 J Biol Chem
Human COL7A1-corrected induced pluripotent stem cells for the treatment of recessive dystrophic epidermolysis bullosa. 2014 Sci Transl Med
Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors. 2014 Cell Rep
Cell Junctions in the Specialized Conduction System of the Heart. 2014 Cell Commun Adhes
Genetic removal of matrix metalloproteinase 9 rescues the symptoms of fragile x syndrome in a mouse model. 2014 J Neurosci
Crosstalk Between Adrenergic and Toll-Like Receptors in Human Mesenchymal Stem Cells and Keratinocytes: A Recipe for Impaired Wound Healing. 2014 Stem Cells Transl Med
Fetal Intervention Increases Maternal T Cell Awareness of the Foreign Conceptus and Can Lead to Immune-Mediated Fetal Demise. 2014 J Immunol
Differentiation of pluripotent stem cells into retinal pigmented epithelium. 2014 Dev Ophthalmol
Existing cardiomyocytes generate cardiomyocytes at a low rate after birth in mice. 2014 Proc Natl Acad Sci U S A
Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions. 2014 J Comp Neurol
Inner ear hair cell-like cells from human embryonic stem cells. 2014 Stem Cells Dev
Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming. 2014 Mol Cell
Human induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. 2014 Hum Mol Genet
Fate of iPSCs Derived from Azoospermic and Fertile Men following Xenotransplantation to Murine Seminiferous Tubules. 2014 Cell Rep
Mouse liver repopulation with hepatocytes generated from human fibroblasts. 2014 Nature
Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns. 2014 Proc Natl Acad Sci U S A
Tbr2 is required to generate a neural circuit mediating the pupillary light reflex. 2014 J Neurosci
Cell-specific translational profiling in acute kidney injury. 2014 J Clin Invest
Potential for Cell Therapy in Parkinson's Disease Using Genetically-Programmed Human Embryonic Stem Cell-Derived Neural Progenitor Cells. 2014 J Comp Neurol
Technical Variations in Low-Input RNA-seq Methodologies. 2014 Sci Rep
Modular plasmonic nanocarriers for efficient and targeted delivery of cancer-therapeutic siRNA. 2014 Nano Lett
Engineering the human thymic microenvironment to support thymopoiesis in vivo. 2014 Stem Cells
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. 2014 Nat Med
Calcium Transients Closely Reflect Prolonged Action Potentials in iPSC Models of Inherited Cardiac Arrhythmia. 2014 Stem Cell Reports
Targeted gene correction minimally impacts whole-genome mutational load in human-disease-specific induced pluripotent stem cell clones. 2014 Cell Stem Cell
Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules. 2014 Hum Mol Genet
Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway. 2014 Cell Rep
Cardiospheres reverse adverse remodeling in chronic rat myocardial infarction: roles of soluble endoglin and Tgf-beta signaling. 2014 Basic Res Cardiol
m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. 2014 Cell Stem Cell
Hypoxia-Inducible Factor (HIF)/Vascular Endothelial Growth Factor (VEGF) Signaling in the Retina. 2014 Adv Exp Med Biol
Endogenous WNT Signaling Regulates hPSC-Derived Neural Progenitor Cell Heterogeneity and Specifies Their Regional Identity. 2014 Stem Cell Reports
miR-34/449 miRNAs are required for motile ciliogenesis by repressing cp110. 2014 Nature
Biomaterial microenvironments to support the generation of new neurons in the adult brain. 2014 Stem Cells
Translational Profiles of Medullary Myofibroblasts during Kidney Fibrosis. 2014 J Am Soc Nephrol
Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant. 2014 Mol Ther
Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice. 2014 Nat Med
LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction. 2014 Neurobiol Dis
Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. 2014 Nature
Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells. 2014 Stem Cells
Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. 2014 Stem Cells
Critical roles of a small conductance Ca2+-activated K+ channel (SK3) in the repolarization process of atrial myocytes. 2014 Cardiovasc Res
Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1. 2014 Stem Cell Reports
Enhancer-trap Flippase Lines for Clonal Analysis in the Drosophila Ovary. 2014 G3 (Bethesda)
COE Loss-of-Function Analysis Reveals a Genetic Program Underlying Maintenance and Regeneration of the Nervous System in Planarians. 2014 PLoS Genet
Tracking migration during human T cell development. 2014 Cell Mol Life Sci


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