Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Ptch2 mediates the Shh response in Ptch1-/- cells. 2014 Development
Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development. 2014 J Dent Res
Neonatal immune-tolerance in mice does not prevent xenograft rejection. 2014 Exp Neurol
Human Lymphoid Development in the Absence of Common gamma-Chain Receptor Signaling. 2014 J Immunol
HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. 2014 PLoS Genet
A long noncoding RNA protects the heart from pathological hypertrophy. 2014 Nature
Utilizing Stem Cell-Derived RPE Cells as A Therapeutic Intervention for Age-Related Macular Degeneration. 2014 Adv Exp Med Biol
Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. 2014 Proc Natl Acad Sci U S A
Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. 2014 Cancer Prev Res (Phila)
Human Neural Stem Cells Survive Long Term in the Midbrain of Dopamine-Depleted Monkeys After GDNF Overexpression and Project Neurites Toward an Appropriate Target. 2014 Stem Cells Transl Med
Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells. 2014 J Vis Exp
Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. 2014 Nat Commun
Engineering strategies to mimic the glioblastoma microenvironment. 2014 Adv Drug Deliv Rev
Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming. 2014 Cell Stem Cell
Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. 2014 Nature
STAT3 Phosphorylation at Tyrosine 705 and Serine 727 Differentially Regulates Mouse ESC Fates. 2014 Stem Cells
Discovery of consensus gene signature and intermodular connectivity defining self-renewal of human embryonic stem cells. 2014 Stem Cells
The past, present and future of stem cell clinical trials for ALS. 2014 Exp Neurol
Enhanced Genetic Modification of Adult Growth Factor Mobilized Peripheral Blood Hematopoietic Stem and Progenitor Cells With Rapamycin. 2014 Stem Cells Transl Med
Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis. 2014 Stem Cell Reports
Human induced pluripotent stem cell-derived cardiomyocytes as an in vitro model for coxsackievirus B3-induced myocarditis and antiviral drug screening platform. 2014 Circ Res
Reprogramming Human Retinal Pigmented Epithelial Cells to Neurons Using Recombinant Proteins. 2014 Stem Cells Transl Med
Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. 2014 Nat Immunol
Automated Video-Based Analysis of Contractility and Calcium Flux in Human-Induced Pluripotent Stem-Derived Cardiomyocytes Cultured over Different Spatial Scales. 2014 Tissue Eng Part C Methods
Recombinase-Mediated Reprogramming and Dystrophin Gene Addition in mdx Mouse Induced Pluripotent Stem Cells. 2014 PLoS One
Shaking up the salt and pepper: origins of cellular heterogeneity in the inner cell mass of the blastocyst. 2014 EMBO J
Defining the role of oxygen tension in human neural progenitor fate. 2014 Stem Cell Reports
Activation of neuronal gene expression by the JMJD3 demethylase is required for postnatal and adult brain neurogenesis. 2014 Cell Rep
Moving beyond surrogate endpoints in cell therapy trials for heart disease. 2014 Stem Cells Transl Med
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. 2014 Proc Natl Acad Sci U S A
Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization of Cardiac Cells. 2014 Methods Mol Biol
Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. 2014 Cell Stem Cell
Human neural progenitor cells generated from induced pluripotent stem cells can survive, migrate, and integrate in the rodent spinal cord. 2014 J Comp Neurol
Interventional Magnetic Resonance Imaging-Guided Cell Transplantation into the Brain with Radially Branched Deployment. 2014 Mol Ther
(19)F spin-lattice relaxation of perfluoropolyethers: Dependence on temperature and magnetic field strength (7.0-14.1T). 2014 J Magn Reson
Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. 2014 Cell Rep
Subventricular spread of diffuse intrinsic pontine glioma. 2014 Acta Neuropathol
Single-molecule super-resolution light-sheet microscopy. 2014 Chemphyschem
Reliable Generation of Induced Pluripotent Stem Cells From Human Lymphoblastoid Cell Lines. 2014 Stem Cells Transl Med
Neural stem cells improve intracranial nanoparticle retention and tumor-selective distribution. 2014 Future Oncol
Developing Defined and Scalable 3D Culture Systems for Culturing Human Pluripotent Stem Cells at High Densities. 2014 Cell Mol Bioeng
The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells. 2014 Proc Natl Acad Sci U S A
Upregulation of CD11A on Hematopoietic Stem Cells Denotes the Loss of Long-Term Reconstitution Potential. 2014 Stem Cell Reports
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain. 2014 Science
Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. 2014 Elife
Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss. 2014 Hippocampus
The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny. 2014 PLoS One
Multiple conserved regulatory domains promote Fezf2 expression in the developing cerebral cortex. 2014 Neural Dev
Combining perfluorocarbon and superparamagnetic iron-oxide cell labeling for improved and expanded applications of cellular MRI. 2014 Magn Reson Med
Human germ cell formation in xenotransplants of induced pluripotent stem cells carrying X chromosome aneuploidies. 2014 Sci Rep

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