Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism. 2016 Cell Metab
Intronic polyadenylation of PDGFRalpha in resident stem cells attenuates muscle fibrosis. 2016 Nature
A human neurodevelopmental model for Williams syndrome. 2016 Nature
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. 2016 Cell
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. 2016 Nat Commun
Induction of site-specific chromosomal translocations in embryonic stem cells by CRISPR/Cas9. 2016 Sci Rep
Functional Human and Murine Tissue-Engineered Liver Is Generated From Adult Stem/Progenitor Cells. 2016 Stem Cells Transl Med
Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells. 2016 Mol Ther Methods Clin Dev
Vertical sleeve gastrectomy activates GPBAR-1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice. 2016 Hepatology
Cells with surface expression of CD133(high)CD71(low) are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas. 2016 Stem Cell Res
Bradykinin promotes neuron-generating division of neural progenitor cells through ERK activation. 2016 J Cell Sci
RNA-binding protein CPEB1 remodels host and viral RNA landscapes. 2016 Nat Struct Mol Biol
A 3D culture system enhances the ability of human bone marrow stromal cells to support the growth of limbal stem/progenitor cells. 2016 Stem Cell Res
IGF1 neuronal response in the absence of MECP2 is dependent on TRalpha 3. 2016 Hum Mol Genet
Monitoring developmental force distributions in reconstituted embryonic epithelia. 2016 Methods
Increased Expression of System xc- in Glioblastoma Confers an Altered Metabolic State and Temozolomide Resistance. 2016 Mol Cancer Res
Hyaluronan as a therapeutic target in human diseases. 2016 Adv Drug Deliv Rev
A dynamic mode of mitotic bookmarking by transcription factors. 2016 Elife
Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice. 2016 PLoS One
Conversion of human fibroblasts into functional cardiomyocytes by small molecules. 2016 Science
An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development. 2016 Sci Data
Protein-RNA Networks Regulated by Normal and ALS-Associated Mutant HNRNPA2B1 in the Nervous System. 2016 Neuron
Muscle Tissue Engineering Using Gingival Mesenchymal Stem Cells Encapsulated in Alginate Hydrogels Containing Multiple Growth Factors. 2016 Ann Biomed Eng
ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium. 2016 Transl Vis Sci Technol
Transcription factor TBX4 regulates myofibroblast accumulation and lung fibrosis. 2016 J Clin Invest
Paramagnetic fluorinated nanoemulsions for sensitive cellular fluorine-19 magnetic resonance imaging. 2016 Nat Mater
Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to stiffness. 2016 J Cell Biol
Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses. 2016 Sci Rep
Hematopoietic stem cell transplantation in immunocompetent hosts without radiation or chemotherapy. 2016 Sci Transl Med
Differential regulation of mouse and human nephron progenitors by the Six family of transcriptional regulators. 2016 Development
Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor. 2016 Cell
A Rational Strategy for the Use of Amniotic Epithelial Stem Cell Therapy for Liver Diseases. 2016 Stem Cells Transl Med
Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease. 2016 Proc Natl Acad Sci U S A
Aggregate formation and suspension culture of human pluripotent stem cells and differentiated progeny. 2016 Methods
Placental transcriptomes in the common aneuploidies reveal critical regions on the trisomic chromosomes and genome-wide effects. 2016 Prenat Diagn
Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination. 2016 Nucleic Acids Res
Hyaluronan synthase 2 regulates fibroblast senescence in pulmonary fibrosis. 2016 Matrix Biol
Non-invasive Chamber-Specific Identification of Cardiomyocytes in Differentiating Pluripotent Stem Cells. 2016 Stem Cell Reports
In vivo blunt-end cloning through CRISPR/Cas9-facilitated non-homologous end-joining. 2016 Nucleic Acids Res
Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. 2016 JCI Insight
Methylome-wide Analysis of Chronic HIV Infection Reveals Five-Year Increase in Biological Age and Epigenetic Targeting of HLA. 2016 Mol Cell
Magnetic Resonance Imaging of Cardiac Strain Pattern Following Transplantation of Human Tissue Engineered Heart Muscles. 2016 Circ Cardiovasc Imaging
TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice. 2016 Gastroenterology
Deletion of the Imprinted Gene Grb10 Promotes Hematopoietic Stem Cell Self-Renewal and Regeneration. 2016 Cell Rep
Design Principles for Engineering of Tissues from Human Pluripotent Stem Cells. 2016 Curr Stem Cell Rep
alphaE-catenin inhibits YAP/TAZ activity to regulate signalling centre formation during tooth development. 2016 Nat Commun
CD13 and ROR2 Permit Isolation of Highly Enriched Cardiac Mesoderm from Differentiating Human Embryonic Stem Cells. 2016 Stem Cell Reports
Vascular Endothelial Growth Factor (VEGF) Bioavailability Regulates Angiogenesis and Intestinal Stem and Progenitor Cell Proliferation during Postnatal Small Intestinal Development. 2016 PLoS One
Increased Gs Signaling in Osteoblasts Reduces Bone Marrow and Whole-Body Adiposity in Male Mice. 2016 Endocrinology


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