Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Elastin-like protein-hyaluronic acid (ELP-HA) hydrogels with decoupled mechanical and biochemical cues for cartilage regeneration. 2017 Biomaterials
Human Embryonic Stem Cells Do Not Change Their X Inactivation Status during Differentiation. 2017 Cell Rep
Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion. 2017 Aging Cell
Genome Editing Techniques and Their Therapeutic Applications. 2017 Clin Pharmacol Ther
Characterization of the Corneal Subbasal Nerve Plexus in Limbal Stem Cell Deficiency. 2017 Cornea
A 3D Tissue-Printing Approach for Validation of Diffusion Tensor Imaging in Skeletal Muscle. 2017 Tissue Eng Part A
iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. 2017 Neuron
Contractile force generation by 3D hiPSC-derived cardiac tissues is enhanced by rapid establishment of cellular interconnection in matrix with muscle-mimicking stiffness. 2017 Biomaterials
Systematic optimization of an engineered hydrogel allows for selective control of human neural stem cell survival and differentiation after transplantation in the stroke brain. 2016 Biomaterials
Chromosome conformation elucidates regulatory relationships in developing human brain. 2016 Nature
alpha-Ketoglutarate Accelerates the Initial Differentiation of Primed Human Pluripotent Stem Cells. 2016 Cell Metab
Reactivating Fetal Hemoglobin Expression in Human Adult Erythroblasts Through BCL11A Knockdown Using Targeted Endonucleases. 2016 Mol Ther Nucleic Acids
Maternal Human Immunodeficiency Virus-Associated Hypergammaglobulinemia Reduces Transplacental Transfer of Immunoglobulin G to Plasmodium falciparum Antigens in Cameroonian Neonates. 2016 Open Forum Infect Dis
Influence of Intermittent Preventive Treatment on Antibodies to VAR2CSA in Pregnant Cameroonian Women. 2016 Am J Trop Med Hyg
Alcohol-induced suppression of KDM6B dysregulates the mineralization potential in dental pulp stem cells. 2016 Stem Cell Res
Genetic Tagging During Human Mesoderm Differentiation Reveals Tripotent Lateral Plate Mesodermal Progenitors. 2016 Stem Cells
Medial HOXA genes demarcate haematopoietic stem cell fate during human development. 2016 Nat Cell Biol
Differentiation of human embryonic stem cells to HOXA+ hemogenic vasculature that resembles the aorta-gonad-mesonephros. 2016 Nat Biotechnol
Multifactorial Optimizations for Directing Endothelial Fate from Stem Cells. 2016 PLoS One
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy. 2016 N Engl J Med
ROCK inhibitor primes human induced pluripotent stem cells to selectively differentiate towards mesendodermal lineage via epithelial-mesenchymal transition-like modulation. 2016 Stem Cell Res
Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice. 2016 J Assoc Res Otolaryngol
Spatiotemporal Reconstruction of the Human Blastocyst by Single-Cell Gene-Expression Analysis Informs Induction of Naive Pluripotency. 2016 Dev Cell
Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos. 2016 Cell Stem Cell
Stem cells and interspecies chimaeras. 2016 Nature
Msx1 and Msx2 function together in the regulation of primordial germ cell migration in the mouse. 2016 Dev Biol
Incubator embedded cell culture imaging system (EmSight) based on Fourier ptychographic microscopy. 2016 Biomed Opt Express
Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward. 2016 J Neurosci
Smoking-Relevant Nicotine Concentration Attenuates the Unfolded Protein Response in Dopaminergic Neurons. 2016 J Neurosci
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. 2016 Nat Biotechnol
Targeted Type 2 Alveolar Cell Depletion. A Dynamic Functional Model for Lung Injury Repair. 2016 Am J Respir Cell Mol Biol
Transplanted Human Stem Cell-Derived Interneuron Precursors Mitigate Mouse Bladder Dysfunction and Central Neuropathic Pain after Spinal Cord Injury. 2016 Cell Stem Cell
Improved Mobilization of Exogenous Mesenchymal Stem Cells to Bone for Fracture Healing and Sex Difference. 2016 Stem Cells
Altered proliferation and networks in neural cells derived from idiopathic autistic individuals. 2016 Mol Psychiatry
Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatan minipigs. 2016 Graefes Arch Clin Exp Ophthalmol
Inferring causal molecular networks: empirical assessment through a community-based effort. 2016 Nat Methods
Existence of Normal Limbal Epithelium in Eyes With Clinical Signs of Total Limbal Stem Cell Deficiency. 2016 Cornea
Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. 2016 Mol Ther Methods Clin Dev
Gene expression changes in the retina following subretinal injection of human neural progenitor cells into a rodent model for retinal degeneration. 2016 Mol Vis
Stem Cell Therapy in Nonneovascular Age-Related Macular Degeneration. 2016 Invest Ophthalmol Vis Sci
NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism. 2016 Cell Metab
Intronic polyadenylation of PDGFRalpha in resident stem cells attenuates muscle fibrosis. 2016 Nature
A human neurodevelopmental model for Williams syndrome. 2016 Nature
Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. 2016 Cell
The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model. 2016 Nat Commun
Induction of site-specific chromosomal translocations in embryonic stem cells by CRISPR/Cas9. 2016 Sci Rep
Functional Human and Murine Tissue-Engineered Liver Is Generated From Adult Stem/Progenitor Cells. 2016 Stem Cells Transl Med
Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells. 2016 Mol Ther Methods Clin Dev
Vertical sleeve gastrectomy activates GPBAR-1/TGR5 to sustain weight loss, improve fatty liver, and remit insulin resistance in mice. 2016 Hepatology


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