Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Crosstalk Between Adrenergic and Toll-Like Receptors in Human Mesenchymal Stem Cells and Keratinocytes: A Recipe for Impaired Wound Healing. 2014 Stem Cells Transl Med
Fetal Intervention Increases Maternal T Cell Awareness of the Foreign Conceptus and Can Lead to Immune-Mediated Fetal Demise. 2014 J Immunol
Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture 2014 Advanced Healthcare Materials
Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno-free conditions. 2014 J Comp Neurol
Inner ear hair cell-like cells from human embryonic stem cells. 2014 Stem Cells Dev
Innate Antiviral Host Defense Attenuates TGF-beta Function through IRF3-Mediated Suppression of Smad Signaling. 2014 Mol Cell
microRNAs and cilia: An ancient connection. 2014 Cell Cycle
Human induced pluripotent stem cells pave the road for a better understanding of motor neuron disease. 2014 Hum Mol Genet
Wnt signaling regulates homeostasis of the periodontal ligament. 2014 J Periodontal Res
Human cytomegalovirus infection of human embryonic stem cell-derived primitive neural stem cells is restricted at several steps but leads to the persistence of viral DNA. 2014 J Virol
Wnt/Catenin Signaling in Adult Stem Cell Physiology and Disease. 2014 Stem Cell Rev
Cell Junctions in the Specialized Conduction System of the Heart. 2014 Cell Commun Adhes
Human embryonic stem cell derived-mesenchymal stem cells: an alternative mesenchymal stem cell source for regenerative medicine therapy. 2014 Regen Med
Targeted delivery of mesenchymal stem cells to the bone. 2014 Bone
Potential for Cell Therapy in Parkinson's Disease Using Genetically-Programmed Human Embryonic Stem Cell-Derived Neural Progenitor Cells. 2014 J Comp Neurol
X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency. 2014 Cell
Technical Variations in Low-Input RNA-seq Methodologies. 2014 Sci Rep
A systems biology approach for defining the molecular framework of the hematopoietic stem cell niche. 2014 Cell Stem Cell
Actin and dynamin2 dynamics and interplay during clathrin-mediated endocytosis. 2014 J Cell Biol
Engineering the human thymic microenvironment to support thymopoiesis in vivo. 2014 Stem Cells
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles. 2014 Nat Med
Embryonic and adult-derived resident cardiac macrophages are maintained through distinct mechanisms at steady state and during inflammation. 2014 Immunity
Fate of iPSCs Derived from Azoospermic and Fertile Men following Xenotransplantation to Murine Seminiferous Tubules. 2014 Cell Rep
Mouse liver repopulation with hepatocytes generated from human fibroblasts. 2014 Nature
Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3. 2014 Development
Isolation, culture, and imaging of human fetal pancreatic cell clusters. 2014 J Vis Exp
Replication of Mycobacterium tuberculosis in retinal pigment epithelium. 2014 JAMA Ophthalmol
Single-cell gene expression profiles define self-renewing, pluripotent, and lineage primed States of human pluripotent stem cells. 2014 Stem Cell Reports
Reorganization of enhancer patterns in transition from naive to primed pluripotency. 2014 Cell Stem Cell
Tbr2 is required to generate a neural circuit mediating the pupillary light reflex. 2014 J Neurosci
Pharmacological induction of pancreatic islet cell transdifferentiation: relevance to type I diabetes. 2014 Cell Death Dis
Mechanisms of action of hESC-secreted proteins that enhance human and mouse myogenesis 2014 Aging
LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction. 2014 Neurobiol Dis
Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. 2014 Nature
Modeling non-syndromic autism and the impact of TRPC6 disruption in human neurons. 2014 Mol Psychiatry
Erythropoiesis from human embryonic stem cells through erythropoietin-independent AKT signaling. 2014 Stem Cells
Critical roles of a small conductance Ca2+-activated K+ channel (SK3) in the repolarization process of atrial myocytes. 2014 Cardiovasc Res
Fate of induced pluripotent stem cells following transplantation to murine seminiferous tubules. 2014 Hum Mol Genet
Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway. 2014 Cell Rep
Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity. 2014 J Biol Chem
sRNA-seq analysis of human embryonic stem cells and definitive endoderm reveal differentially expressed microRNAs and novel isomiRs with distinct targets. 2014 Stem Cells
Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies. 2014 J Neurosci
Hypoxia-Inducible Factor (HIF)/Vascular Endothelial Growth Factor (VEGF) Signaling in the Retina. 2014 Adv Exp Med Biol
Serine integrase chimeras with activity in E. coli and HeLa cells. 2014 Biol Open
Nuclear receptor TLX stimulates hippocampal neurogenesis and enhances learning and memory in a transgenic mouse model. 2014 Proc Natl Acad Sci U S A
Biomaterial microenvironments to support the generation of new neurons in the adult brain. 2014 Stem Cells
An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons. 2014 Nature
HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice. 2014 Cancer Res
Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development. 2014 J Dent Res
Neonatal immune-tolerance in mice does not prevent xenograft rejection. 2014 Exp Neurol


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