Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Identification by automated screening of a small molecule that selectively eliminates neural stem cells derived from hESCs but not dopamine neurons. 2009 PLoS One
Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent. 2009 Dev Biol
Adult mice generated from induced pluripotent stem cells. 2009 Nature
Renal ontogeny in the rhesus monkey (Macaca mulatta) and directed differentiation of human embryonic stem cells towards kidney precursors. 2009 Differentiation
A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. 2009 PLoS One
Anatomic demarcation of cells: genes to patterns. 2009 Science
Digital RNA allelotyping reveals tissue-specific and allele-specific gene expression in human. 2009 Nat Methods
G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies. 2009 PLoS One
Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. 2009 Blood
Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation. 2009 Immunol Res
Fibroblast growth factor 10 plays a causative role in the tracheal cartilage defects in a mouse model of Apert syndrome. 2009 Pediatr Res
Endogenous Wnt signaling maintains neural progenitor cell potency. 2009 Stem Cells
Molecular imaging of human embryonic stem cells. 2009 Methods Mol Biol
An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. 2009 Nat Struct Mol Biol
Dlx1&2 and Mash1 transcription factors control striatal patterning and differentiation through parallel and overlapping pathways. 2009 J Comp Neurol
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation. 2009 Proc Natl Acad Sci U S A
Sustained in vitro intestinal epithelial culture within a Wnt-dependent stem cell niche. 2009 Nat Med
Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues. 2009 Leukemia
Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells. 2009 Stem Cells
Optimal timing of inner cell mass isolation increases the efficiency of human embryonic stem cell derivation and allows generation of sibling cell lines. 2009 Cell Stem Cell
Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation. 2009 Cancer Res
Parsing the niche code: the molecular mechanisms governing hematopoietic stem cell adhesion and differentiation. 2009 Haematologica
Genic regions of a large salamander genome contain long introns and novel genes. 2009 BMC Genomics
Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation. 2009 Nature
Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. 2009 Cereb Cortex
Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. 2009 BMC Genomics
Linking the p53 tumour suppressor pathway to somatic cell reprogramming. 2009 Nature
Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology. 2009 Stem Cells Dev
New regulatory mechanisms of TGF-beta receptor function. 2009 Trends Cell Biol
Temporally precise in vivo control of intracellular signalling. 2009 Nature
Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. 2009 PLoS One
Identification and characterization of posttranslational modification-specific binding proteins in vivo by mammalian tethered catalysis. 2009 Proc Natl Acad Sci U S A
Transforming growth factor-alpha induces neurogenesis and behavioral improvement in a chronic stroke model. 2009 Neuroscience
Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis. 2009 Nature
Cultivating liver cells on printed arrays of hepatocyte growth factor. 2009 Biomaterials
Facilitated maturation of Ca2+ handling properties of human embryonic stem cell-derived cardiomyocytes by calsequestrin expression. 2009 Am J Physiol Cell Physiol
Immune influence on adult neural stem cell regulation and function. 2009 Neuron
PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis. 2009 J Biol Chem
Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. 2009 Proc Natl Acad Sci U S A
Early postnatal proteolipid promoter-expressing progenitors produce multilineage cells in vivo. 2009 J Neurosci
Directing hepatic differentiation of embryonic stem cells with protein microarray-based co-cultures. 2009 Integr Biol (Camb)
Molecular aging and rejuvenation of human muscle stem cells. 2009 EMBO Mol Med
Derivation of primordial germ cells from human embryonic and induced pluripotent stem cells is significantly improved by coculture with human fetal gonadal cells. 2009 Stem Cells
A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. 2009 Cell
Human DNA methylomes at base resolution show widespread epigenomic differences. 2009 Nature
A central role for the small GTPase Rac1 in hippocampal plasticity and spatial learning and memory. 2009 Mol Cell Neurosci
Journal club. A cell biologist looks at the risk and promise of a new insight into stem cells and cancer. 2009 Nature
Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitions. 2009 J Neurosci
Bendamustine therapy in chronic lymphocytic leukemia. 2009 Expert Opin Pharmacother
The adhesion molecule esam1 is a novel hematopoietic stem cell marker. 2009 Stem Cells

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