Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Cytokines and CNS development. 2009 Neuron
Common variable immunodeficiency: etiological and treatment issues. 2009 Int Arch Allergy Immunol
Gene targeting in a HUES line of human embryonic stem cells via electroporation. 2009 Stem Cells
Parkin, PINK1, and DJ-1 form a ubiquitin E3 ligase complex promoting unfolded protein degradation. 2009 J Clin Invest
Analyses of regenerative wave patterns in adult hair follicle populations reveal macro-environmental regulation of stem cell activity. 2009 Int J Dev Biol
Chronic myeloproliferative diseases with and without the Ph chromosome: some unresolved issues. 2009 Leukemia
Molecular characterization of the human NANOG protein. 2009 Stem Cells
Expanding the genetic code for biological studies. 2009 Chem Biol
TOX3 regulates calcium-dependent transcription in neurons. 2009 Proc Natl Acad Sci U S A
Quo vadis, hair cell regeneration? 2009 Nat Neurosci
Lentiviral vectors and protocols for creation of stable hESC lines for fluorescent tracking and drug resistance selection of cardiomyocytes. 2009 PLoS One
Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation. 2009 Nature
Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain. 2009 Development
Parkinson-linked genes and toxins that affect neuronal cell death through the Bcl-2 family. 2009 Antioxid Redox Signal
Deconstructing stem cell tumorigenicity: a roadmap to safe regenerative medicine. 2009 Stem Cells
Histone modifications at human enhancers reflect global cell-type-specific gene expression. 2009 Nature
Signed weighted gene co-expression network analysis of transcriptional regulation in murine embryonic stem cells. 2009 BMC Genomics
A targeted neuroglial reporter line generated by homologous recombination in human embryonic stem cells. 2009 Stem Cells
A conserved mechanism for control of human and mouse embryonic stem cell pluripotency and differentiation by shp2 tyrosine phosphatase. 2009 PLoS One
EphA4 as an effector of Twist1 in the guidance of osteogenic precursor cells during calvarial bone growth and in craniosynostosis. 2009 Development
Posterior malformations in Dact1 mutant mice arise through misregulated Vangl2 at the primitive streak. 2009 Nat Genet
Versatile synthesis and rational design of caged morpholinos. 2009 J Am Chem Soc
Imaging of STAT3 signaling pathway during mouse embryonic stem cell differentiation. 2009 Stem Cells Dev
A variable torque motor compatible with magnetic resonance imaging. 2009 Rev Sci Instrum
Adult mice generated from induced pluripotent stem cells. 2009 Nature
High-content screening of primary neurons: ready for prime time. 2009 Curr Opin Neurobiol
Mesenchymal stem cells derived from human gingiva are capable of immunomodulatory functions and ameliorate inflammation-related tissue destruction in experimental colitis. 2009 J Immunol
Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liver. 2009 Genome Res
Mesenchymal stem cell-mediated ectopic hematopoiesis alleviates aging-related phenotype in immunocompromised mice. 2009 Blood
PARP-1 deficiency increases the severity of disease in a mouse model of multiple sclerosis. 2009 J Biol Chem
Induced pluripotent stem cells and embryonic stem cells are distinguished by gene expression signatures. 2009 Cell Stem Cell
Molecular aging and rejuvenation of human muscle stem cells. 2009 EMBO Mol Med
Mef2C is a lineage-restricted target of Scl/Tal1 and regulates megakaryopoiesis and B-cell homeostasis. 2009 Blood
Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation. 2009 Immunol Res
Pluripotent stem cell-derived gametes: truth and (potential) consequences. 2009 Cell Stem Cell
Functional and transcriptional characterization of human embryonic stem cell-derived endothelial cells for treatment of myocardial infarction. 2009 PLoS One
An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells. 2009 Nat Struct Mol Biol
FoxO3 regulates neural stem cell homeostasis. 2009 Cell Stem Cell
Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. 2009 Stem Cells
Tumor-like stem cells derived from human keloid are governed by the inflammatory niche driven by IL-17/IL-6 axis. 2009 PLoS One
Glycogen synthase kinase 3beta missplicing contributes to leukemia stem cell generation. 2009 Proc Natl Acad Sci U S A
Bendamustine therapy in chronic lymphocytic leukemia. 2009 Expert Opin Pharmacother
Integrated chemical genomics reveals modifiers of survival in human embryonic stem cells. 2009 Stem Cells
MicroRNA profiling of human-induced pluripotent stem cells. 2009 Stem Cells Dev
Noninvasive de novo imaging of human embryonic stem cell-derived teratoma formation. 2009 Cancer Res
Abeta-specific Th2 cells provide cognitive and pathological benefits to Alzheimer's mice without infiltrating the CNS. 2009 Neurobiol Dis
Genic regions of a large salamander genome contain long introns and novel genes. 2009 BMC Genomics
nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis. 2009 PLoS One
A role for von Hippel-Lindau protein in pancreatic beta-cell function. 2009 Diabetes
Defining long-term maintenance conditions of human embryonic stem cells with arrayed cellular microenvironment technology. 2009 Stem Cells Dev

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