Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Targeted mutation of the mouse Grp94 gene disrupts development and perturbs endoplasmic reticulum stress signaling. 2010 PLoS One
Efficient generation of functional dopaminergic neurons from human induced pluripotent stem cells under defined conditions. 2010 Stem Cells
Bmi-1 is a crucial regulator of prostate stem cell self-renewal and malignant transformation. 2010 Cell Stem Cell
Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. 2010 J Clin Invest
Dynamic changes in the human methylome during differentiation. 2010 Genome Res
Hybrid median filter background estimator for correcting distortions in microtiter plate data. 2010 Assay Drug Dev Technol
Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes. 2010 Hum Mol Genet
The histone demethylase UTX enables RB-dependent cell fate control. 2010 Genes Dev
Regulated expansion of human pancreatic beta-cells. 2010 Mol Ther
MicroRNA let-7b regulates neural stem cell proliferation and differentiation by targeting nuclear receptor TLX signaling. 2010 Proc Natl Acad Sci U S A
An amyloid-notch hypothesis for Alzheimer's disease. 2010 Neuroscientist
Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. 2010 PLoS One
HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors. 2010 Mol Aspects Med
Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells. 2010 Stem Cells
Variations of X chromosome inactivation occur in early passages of female human embryonic stem cells. 2010 PLoS One
Parallel gateways to pluripotency: open chromatin in stem cells and development. 2010 Curr Opin Genet Dev
Long-term human pluripotent stem cell self-renewal on synthetic polymer surfaces. 2010 Biomaterials
Histological and functional benefit following transplantation of motor neuron progenitors to the injured rat spinal cord. 2010 PLoS One
HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype. 2010 J Clin Invest
Stem Cells' position statement on hESC research. 2010 Stem Cells
MicroRNAs control hepatocyte proliferation during liver regeneration. 2010 Hepatology
Deconstructing pancreas development to reconstruct human islets from pluripotent stem cells. 2010 Cell Stem Cell
Multilayered specification of the T-cell lineage fate. 2010 Immunol Rev
PET imaging of the immune system: immune monitoring at the whole body level. 2010 Q J Nucl Med Mol Imaging
Quantitative analysis of cellular inflammation after traumatic spinal cord injury: evidence for a multiphasic inflammatory response in the acute to chronic environment. 2010 Brain
Differentiation and characterization of metabolically functioning hepatocytes from human embryonic stem cells. 2010 Stem Cells
A model of motor neuron loss: selective deficits after ricin injection. 2010 J Neurotrauma
Chromatin regulation by Brg1 underlies heart muscle development and disease. 2010 Nature
MicroRNA-9 coordinates proliferation and migration of human embryonic stem cell-derived neural progenitors. 2010 Cell Stem Cell
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation. 2010 Nature
Method for Decellularizing Skeletal Muscle Without Detergents or Proteolytic Enzymes. 2010 Tissue Eng Part C Methods
Vascular remodeling of the vitelline artery initiates extravascular emergence of hematopoietic clusters. 2010 Blood
Cardiac myocyte force development during differentiation and maturation. 2010 Ann N Y Acad Sci
Memory in Induced Pluripotent Stem Cells: Reprogrammed Human Retinal Pigmented Epithelial Cells Show Tendency for Spontaneous Redifferentiation. 2010 Stem Cells
Cancer-associated fibroblasts enhance the gland-forming capability of prostate cancer stem cells. 2010 Cancer Res
Alternative splicing regulates mouse embryonic stem cell pluripotency and differentiation. 2010 Proc Natl Acad Sci U S A
Reprogramming of human primary somatic cells by OCT4 and chemical compounds. 2010 Cell Stem Cell
Parthenogenic blastocysts derived from cumulus-free in vitro matured human oocytes. 2010 PLoS One
Immature B-cell progenitors survive oncogenic stress and efficiently initiate Ph+ B-acute lymphoblastic leukemia. 2010 Blood
Hydrogel matrix to support stem cell survival after brain transplantation in stroke. 2010 Neurorehabil Neural Repair
Expression of migration-related genes is progressively upregulated in murine Lineage-Sca-1+c-Kit+ population from the fetal to adult stages of development. 2010 Stem Cell Res Ther
Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors. 2010 Development
Cell-based immunotherapy with mesenchymal stem cells cures bisphosphonate-related osteonecrosis of the jaw-like disease in mice. 2010 J Bone Miner Res
Disease research and drug development models based on genetically altered human embryonic stem cells. 2010 Discov Med
Human primordial germ cell formation is diminished by exposure to environmental toxicants acting through the AHR signaling pathway. 2010 Toxicol Sci
Female human iPSCs retain an inactive X chromosome. 2010 Cell Stem Cell
Ontogeny of the kidney and renal developmental markers in the rhesus monkey (Macaca mulatta). 2010 Anat Rec (Hoboken)
G1 arrest and differentiation can occur independently of Rb family function. 2010 J Cell Biol
FragSeq: transcriptome-wide RNA structure probing using high-throughput sequencing. 2010 Nat Methods
Human neural stem cells differentiate and promote locomotor recovery in an early chronic spinal cord injury NOD-scid mouse model. 2010 PLoS One


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