Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Characterization of an In Vitro Differentiation Assay for Pancreatic-Like Cell Development from Murine Embryonic Stem Cells: Detailed Gene Expression Analysis. 2011 Assay Drug Dev Technol
Inducing iPSCs to escape the dish. 2011 Cell Stem Cell
Stereochemical basis for engineered pyrrolysyl-tRNA synthetase and the efficient in vivo incorporation of structurally divergent non-native amino acids. 2011 ACS Chem Biol
The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. 2011 Aging (Albany NY)
Inhibitors of Src and focal adhesion kinase promote endocrine specification: impact on the derivation of beta-cells from human pluripotent stem cells. 2011 J Biol Chem
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. 2011 Proc Natl Acad Sci U S A
Open chromatin in pluripotency and reprogramming. 2011 Nat Rev Mol Cell Biol
Genetically Encoding Unnatural Amino Acids in Neural Stem Cells and Optically Reporting Voltage-Sensitive Domain Changes in Differentiated Neurons. 2011 Stem Cells
Gene Editing of Human Embryonic Stem Cells via an Engineered Baculoviral Vector Carrying Zinc-finger Nucleases. 2011 Mol Ther
Distinct Roles of MicroRNA-1 and -499 in Ventricular Specification and Functional Maturation of Human Embryonic Stem Cell-Derived Cardiomyocytes. 2011 PLoS One
Stem cell gene expression programs influence clinical outcome in human leukemia. 2011 Nat Med
Somatic coding mutations in human induced pluripotent stem cells. 2011 Nature
A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing. 2011 RNA
miR than meets the eye. 2011 Genes Dev
Critical role of PINK1 in regulating Parkin protein levels in vivo. 2011 Arch Neurol
Generating gene knockout rats by homologous recombination in embryonic stem cells. 2011 Nat Protoc
Induced pluripotent stem cells for neural tissue engineering. 2011 Biomaterials
Beyond Phenotype: The Promise of hiPSC-Based Studies of Schizophrenia. 2011 Stem Cells
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. 2011 Nature
Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes. 2011 J Mammary Gland Biol Neoplasia
Multi-scale Biomimetic Topography for the Alignment of Neonatal and Embryonic Stem Cell-derived Heart Cells. 2011 Tissue Eng Part C Methods
Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell. 2011 Proc Natl Acad Sci U S A
Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility. 2011 Hum Mol Genet
Decellularized liver matrix as a carrier for the transplantation of human fetal and primary hepatocytes in mice. 2011 Liver Transpl
Teratoma Generation in the Testis Capsule. 2011 J Vis Exp
Neuropilins are positive regulators of Hedgehog signal transduction. 2011 Genes Dev
Defining the nature of human pluripotent stem cell progeny. 2011 Cell Res
Antimycotic ciclopirox olamine in the diabetic environment promotes angiogenesis and enhances wound healing. 2011 PLoS One
Theranostic effect of serial manganese-enhanced magnetic resonance imaging of human embryonic stem cell derived teratoma. 2011 Magn Reson Med
Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence. 2011 PLoS One
MHC Mismatch Inhibits Neurogenesis and Neuron Maturation in Stem Cell Allografts. 2011 PLoS One
Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells. 2011 Mol Ther
Functional Modules Distinguish Human Induced Pluripotent Stem Cells from Embryonic Stem Cells. 2011 Stem Cells Dev
Enhancers: Multi-dimensional signal integrators. 2011 Transcription
Transcriptomic Signature of Trophoblast Differentiation in a Human Embryonic Stem Cell Model. 2011 Biol Reprod
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. 2011 Nat Biotechnol
Beyond knockout rats: new insights into finer genome manipulation in rats. 2011 Cell Cycle
Nanogel star polymer architectures: a nanoparticle platform for modular programmable macromolecular self-assembly, intercellular transport, and dual-mode cargo delivery. 2011 Adv Mater
Engineering Bi-layer Nanofibrous Conduits for Peripheral Nerve Regeneration. 2011 Tissue Eng Part C Methods
A Chemical Approach to Controlling Cell Fate and Function. 2011 Stem Cells
Radiolabeling and In Vivo Imaging of Transplanted Renal Lineages Differentiated from Human Embryonic Stem Cells in Fetal Rhesus Monkeys. 2011 Mol Imaging Biol
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. 2011 Nat Biotechnol
Computational integration of homolog and pathway gene module expression reveals general stemness signatures. 2011 PLoS One
Akt increases sox2 expression in adult hippocampal neural progenitor cells, but increased sox2 does not promote proliferation. 2011 Stem Cells Dev
Neocortical excitation/inhibition balance in information processing and social dysfunction. 2011 Nature
A Genome-Wide Screen Reveals a Role for microRNA-1 in Modulating Cardiac Cell Polarity. 2011 Dev Cell
Transferable cell-secreted extracellular matrices enhance osteogenic differentiation. 2011 Acta Biomater
Exploiting bacterial peptide display technology to engineer biomaterials for neural stem cell culture. 2011 Biomaterials
Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. 2011 Cell Res
miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. 2011 Nat Commun


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