Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Exploiting the origins of Ras mediated squamous cell carcinoma to develop novel therapeutic interventions. 2011 Small Gtpases
Cell-cell junction remodeling in the heart: Possible role in cardiac conduction system function and arrhythmias? 2011 Life Sci
An antibody against SSEA-5 glycan on human pluripotent stem cells enables removal of teratoma-forming cells. 2011 Nat Biotechnol
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 Science
Annual Research Review: Development of the cerebral cortex: implications for neurodevelopmental disorders. 2011 J Child Psychol Psychiatry
Multi-Dimensional X-Space Magnetic Particle Imaging. 2011 IEEE Trans Med Imaging
Guided Migration of Neural Stem Cells Derived from Human Embryonic Stem Cells by an Electric Field. 2011 Stem Cells
The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-beta. 2011 Biomaterials
Targeting SOX17 in human embryonic stem cells creates unique strategies for isolating and analyzing developing endoderm. 2011 Cell Stem Cell
Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors. 2011 Proc Natl Acad Sci U S A
Antitumor activity from antigen-specific CD8 T cells generated in vivo from genetically engineered human hematopoietic stem cells. 2011 Proc Natl Acad Sci U S A
A New FACS Approach Isolates hESC Derived Endoderm Using Transcription Factors. 2011 PLoS One
Phosphatidylserine directly and positively regulates fusion of myoblasts into myotubes. 2011 Biochem Biophys Res Commun
Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response. 2011 Am J Physiol Lung Cell Mol Physiol
Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. 2011 Proc Natl Acad Sci U S A
Shrink-Film Configurable Multiscale Wrinkles for Functional Alignment of Human Embryonic Stem Cells and their Cardiac Derivatives. 2011 Adv Mater
Sox9-haploinsufficiency causes glucose intolerance in mice. 2011 PLoS One
Reprogramming, transdifferentiation and the shifting landscape of cellular identity. 2011 Cell Cycle
The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. 2011 Aging (Albany NY)
MicroRNA-mediated conversion of human fibroblasts to neurons. 2011 Nature
Open chromatin in pluripotency and reprogramming. 2011 Nat Rev Mol Cell Biol
Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming. 2011 Cell Stem Cell
Small RNA and transcriptional upregulation. 2011 Wiley Interdiscip Rev RNA
Control of B cell development by the histone H2A deubiquitinase MYSM1. 2011 Immunity
Dynamics of Retrieval Strategies for Remote Memories. 2011 Cell
Embryonic stem cells require Wnt proteins to prevent differentiation to epiblast stem cells. 2011 Nat Cell Biol
Fine-tuning of Drp1/Fis1 availability by AKAP121/Siah2 regulates mitochondrial adaptation to hypoxia. 2011 Mol Cell
Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions. 2011 Cell Stem Cell
3D-Spheroid Culture of Human Gingiva-Derived Mesenchymal Stem Cells Enhances Mitigation of Chemotherapy-Induced Oral Mucositis. 2011 Stem Cells Dev
NANOS3 function in human germ cell development. 2011 Hum Mol Genet
The role of anti-mullerian hormone (AMH) in assessing ovarian reserve. 2011 J Clin Endocrinol Metab
Single-cell dissection of transcriptional heterogeneity in human colon tumors. 2011 Nat Biotechnol
Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors. 2011 Proc Natl Acad Sci U S A
Sphingolipid signaling and hematopoietic malignancies: to the rheostat and beyond. 2011 Anticancer Agents Med Chem
Vitamin C treatment promotes mesenchymal stem cell sheet formation and tissue regeneration by elevating telomerase activity. 2011 J Cell Physiol
Mitochondrial cardiomyopathies: how to identify candidate pathogenic mutations by mitochondrial DNA sequencing, MITOMASTER and phylogeny. 2011 Eur J Hum Genet
Derivation of new human embryonic stem cell lines reveals rapid epigenetic progression in vitro that can be prevented by chemical modification of chromatin. 2011 Hum Mol Genet
Inhibitors of Src and focal adhesion kinase promote endocrine specification: impact on the derivation of beta-cells from human pluripotent stem cells. 2011 J Biol Chem
A Novel Role for an RNA Polymerase III Subunit POLR3G in Regulating Pluripotency in Human Embryonic Stem Cells. 2011 Stem Cells
From microRNAs to targets: pathway discovery in cell fate transitions. 2011 Curr Opin Genet Dev
Comparative Transcriptome Analysis of Human Trophectoderm and Embryonic Stem Cell-Derived Trophoblasts Reveal Key Participants in Early Implantation. 2011 Biol Reprod
Placental expression of vascular endothelial growth factor receptor-1/soluble vascular endothelial growth factor receptor-1 correlates with severity of clinical preeclampsia and villous hypermaturity. 2011 Hum Pathol
Recapitulation of the embryonic cardiovascular progenitor cell niche. 2011 Biomaterials
Single cell analysis facilitates staging of blimp1-dependent primordial germ cells derived from mouse embryonic stem cells. 2011 PLoS One
Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis. 2011 J Neurosci
Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. 2011 Nature
Characterization of an In Vitro Differentiation Assay for Pancreatic-Like Cell Development from Murine Embryonic Stem Cells: Detailed Gene Expression Analysis. 2011 Assay Drug Dev Technol
MEF2C Enhances Dopaminergic Neuron Differentiation of Human Embryonic Stem Cells in a Parkinsonian Rat Model. 2011 PLoS One
Genetically Encoding Unnatural Amino Acids in Neural Stem Cells and Optically Reporting Voltage-Sensitive Domain Changes in Differentiated Neurons. 2011 Stem Cells
Highly efficient large-scale lentiviral vector concentration by tandem tangential flow filtration. 2011 J Virol Methods

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