Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Human Neural Stem Cell Transplantation Ameliorates Radiation-Induced Cognitive Dysfunction. 2011 Cancer Res
BCL6-mediated repression of p53 is critical for leukemia stem cell survival in chronic myeloid leukemia. 2011 J Exp Med
Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell. 2011 Proc Natl Acad Sci U S A
Multiscale computational models for optogenetic control of cardiac function. 2011 Biophys J
Uniaxial mechanical strain modulates the differentiation of neural crest stem cells into smooth muscle lineage on micropatterned surfaces. 2011 PLoS One
Modeling psychiatric disorders through reprogramming. 2011 Dis Model Mech
Multi-scale Biomimetic Topography for the Alignment of Neonatal and Embryonic Stem Cell-derived Heart Cells. 2011 Tissue Eng Part C Methods
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions. 2011 Mol Cell
Genetic manipulations in the rat: progress and prospects. 2011 Curr Opin Nephrol Hypertens
The challenges and promises of blood engineered from human pluripotent stem cells. 2011 Adv Drug Deliv Rev
Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence. 2011 PLoS One
MHC Mismatch Inhibits Neurogenesis and Neuron Maturation in Stem Cell Allografts. 2011 PLoS One
Mesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-gamma and TNF-alpha 2011 Nat Med
Computer-Aided 2D and 3D quantification of human stem cell fate from in vitro samples using Volocity high performance image analysis software. 2011 Stem Cell Res
Adaptive optics wide-field microscopy using direct wavefront sensing. 2011 Opt Lett
Transcriptomic Signature of Trophoblast Differentiation in a Human Embryonic Stem Cell Model. 2011 Biol Reprod
Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. 2011 Development
RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites. 2011 Nat Chem Biol
Hemogenic endothelium: origins, regulation, and implications for vascular biology. 2011 Semin Cell Dev Biol
PI3K mediated electrotaxis of embryonic and adult neural progenitor cells in the presence of growth factors. 2011 Exp Neurol
Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. 2011 Dev Biol
Engineering Bi-layer Nanofibrous Conduits for Peripheral Nerve Regeneration. 2011 Tissue Eng Part C Methods
Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members. 2011 PLoS One
Notch post-translationally regulates beta-catenin protein in stem and progenitor cells. 2011 Nat Cell Biol
New Approaches in the Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells toward Hepatocytes. 2011 Stem Cell Rev
Computational integration of homolog and pathway gene module expression reveals general stemness signatures. 2011 PLoS One
Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRTdeficient bone marrow. 2011 Exp Hematol
An Evolved Adeno-associated Viral Variant Enhances Gene Delivery and Gene Targeting in Neural Stem Cells. 2011 Mol Ther
High Throughput MicroRNA Profiling: Optimized Multiplex qRT-PCR at Nanoliter Scale on the Fluidigm Dynamic ArrayTM IFCs. 2011 J Vis Exp
Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. 2011 Cell Res
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. 2011 EMBO J
Adenine nucleotide translocase 1 deficiency results in dilated cardiomyopathy with defects in myocardial mechanics, histopathological alterations, and activation of apoptosis. 2011 JACC Cardiovasc Imaging
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. 2011 Development
Regulation of PCDH15 function in mechanosensory hair cells by alternative splicing of the cytoplasmic domain. 2011 Development
Multiple targets of miR-302 and miR-372 promote reprogramming of human fibroblasts to induced pluripotent stem cells. 2011 Nat Biotechnol
Shrink-induced single-cell plastic microwell array. 2011 J Lab Autom
Control of Embryonic Stem Cell Lineage Commitment by Core Promoter Factor, TAF3. 2011 Cell
A Genome-Wide Screen Reveals a Role for microRNA-1 in Modulating Cardiac Cell Polarity. 2011 Dev Cell
GROalpha regulates human embryonic stem cell self-renewal or adoption of a neuronal fate. 2011 Differentiation
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. 2011 Nature
Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells. 2011 Hum Mol Genet
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. 2011 Development
Role of autonomous androgen receptor signaling in prostate cancer initiation is dichotomous and depends on the oncogenic signal. 2011 Proc Natl Acad Sci U S A
Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells. 2011 Proc Natl Acad Sci U S A
Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells. 2011 J Biol Chem
Sphingolipid signaling and hematopoietic malignancies: to the rheostat and beyond. 2011 Anticancer Agents Med Chem
Optogenetics in neural systems. 2011 Neuron
Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. 2011 Genes Dev
Myelin Restoration: Progress and Prospects for Human Cell Replacement Therapies. 2011 Arch Immunol Ther Exp (Warsz)
Derivation of Smooth Muscle Cells with Neural Crest Origin from Human Induced Pluripotent Stem Cells. 2011 Cells Tissues Organs

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