Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Human iPSC-based Cardiac Microphysiological System For Drug Screening Applications. 2015 Sci Rep
Notch activity modulates the responsiveness of neural progenitors to sonic hedgehog signaling. 2015 Dev Cell
Canonical/beta-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. 2015 Invest Ophthalmol Vis Sci
Proof of concept studies exploring the safety and functional activity of human parthenogenetic-derived neural stem cells for the treatment of Parkinson's disease. 2015 Cell Transplant
Follicle dynamics and global organization in the intact mouse ovary. 2015 Dev Biol
Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss. 2015 PLoS Genet
Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion. 2015 Cell
Single-cell resolution of morphological changes in hemogenic endothelium. 2015 Development
Tolerance induction and reversal of diabetes in mice transplanted with human embryonic stem cell-derived pancreatic endoderm. 2015 Cell Stem Cell
Identification of HECT E3 ubiquitin ligase family genes involved in stem cell regulation and regeneration in planarians. 2015 Dev Biol
Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis. 2015 Cell Rep
Human Disease Modeling Reveals Integrated Transcriptional and Epigenetic Mechanisms of NOTCH1 Haploinsufficiency. 2015 Cell
Transcriptome-wide Analysis Reveals Hallmarks of Human Intestine Development and Maturation In Vitro and In Vivo. 2015 Stem Cell Reports
Embryonic stem cells derived from in vivo or in vitro-generated murine blastocysts display similar transcriptome and differentiation potential. 2015 PLoS One
Ephrin-As are required for the topographic mapping but not laminar choice of physiologically distinct RGC types. 2015 Dev Neurobiol
A Continuous Molecular Roadmap to iPSC Reprogramming through Progression Analysis of Single-Cell Mass Cytometry. 2015 Cell Stem Cell
Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs. 2015 Cell Stem Cell
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas. 2015 N Engl J Med
Early reprogramming regulators identified by prospective isolation and mass cytometry. 2015 Nature
Brief reports: Lysosomal cross-correction by hematopoietic stem cell-derived macrophages via tunneling nanotubes. 2015 Stem Cells
Potential for Cell Therapy in Parkinson's Disease Using Genetically-Programmed Human Embryonic Stem Cell-Derived Neural Progenitor Cells. 2014 J Comp Neurol
Evidence that the DNA endonuclease ARTEMIS also has intrinsic 5'-exonuclease activity. 2014 J Biol Chem
Defining the localization and molecular characteristic of minor salivary gland label retaining cells. 2014 Stem Cells
Long-distance axonal growth from human induced pluripotent stem cells after spinal cord injury. 2014 Neuron
Engineering interpenetrating network hydrogels as biomimetic cell niche with independently tunable biochemical and mechanical properties. 2014 Biomaterials
Role of BRCA1 in brain development. 2014 Proc Natl Acad Sci U S A
Human cardiosphere-derived cells from advanced heart failure patients exhibit augmented functional potency in myocardial repair. 2014 JACC Heart Fail
Breakthroughs in cell therapy for heart disease: focus on cardiosphere-derived cells. 2014 Mayo Clin Proc
Translating stem cell research to cardiac disease therapies: pitfalls and prospects for improvement. 2014 J Am Coll Cardiol
Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac dilatation in porcine ischemic cardiomyopathy. 2014 PLoS One
Angiogenesis, cardiomyocyte proliferation and anti-fibrotic effects underlie structural preservation post-infarction by intramyocardially-injected cardiospheres. 2014 PLoS One
Conversion of Human Fibroblasts into Monocyte-Like Progenitor Cells. 2014 Stem Cells
Mathematical approaches to modeling development and reprogramming. 2014 Proc Natl Acad Sci U S A
Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs. 2014 Nat Commun
Reprogramming by lineage specifiers: blurring the lines between pluripotency and differentiation. 2014 Curr Opin Genet Dev
Stem cells and biopharmaceuticals: vital roles in the growth of tissue-engineered small intestine. 2014 Semin Pediatr Surg
Regenerative medicine: is this the biggest change in surgery? 2014 Semin Pediatr Surg
Delivery of iPS-NPCs to the stroke cavity within a hyaluronic acid matrix promotes the differentiation of transplanted cells 2014 Advanced Functional Materials
Hydrogel design of experiments methodology to optimize hydrogel for iPSC-NPC culture 2014 Advanced Healthcare Materials
Importance of cell-cell contact in the therapeutic benefits of cardiosphere-derived cells. 2014 Stem Cells
RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia. 2014 Nat Genet
Mechanistic rationale for targeting the unfolded protein response in pre-B acute lymphoblastic leukemia. 2014 Proc Natl Acad Sci U S A
Systematic Identification of Barriers to Human iPSC Generation. 2014 Cell
Cardiac regeneration in model organisms. 2014 Curr Treat Options Cardiovasc Med
3D imaging of Sox2 enhancer clusters in embryonic stem cells. 2014 Elife
Natural Killer Cell Subsets Differentially Reject Embryonic Stem Cells Based on Licensing. 2014 Transplantation
An effective approach to prevent immune rejection of human ESC-derived allografts. 2014 Cell Stem Cell
Enhanced trophic factor secretion by mesenchymal stem/stromal cells with Glycine-Histidine-Lysine (GHK)-modified alginate hydrogels. 2014 Acta Biomater
Lysophosphatidic acid protects human mesenchymal stromal cells from differentiation-dependent vulnerability to apoptosis. 2014 Tissue Eng Part A
Histone H3.3 regulates dynamic chromatin states during spermatogenesis. 2014 Development

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