Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Biomaterial microenvironments to support the generation of new neurons in the adult brain. 2014 Stem Cells
An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons. 2014 Nature
HSV-sr39TK positron emission tomography and suicide gene elimination of human hematopoietic stem cells and their progeny in humanized mice. 2014 Cancer Res
Primary Cilia Integrate Hedgehog and Wnt Signaling during Tooth Development. 2014 J Dent Res
Neonatal immune-tolerance in mice does not prevent xenograft rejection. 2014 Exp Neurol
Polyglutamine-expanded androgen receptor interferes with TFEB to elicit autophagy defects in SBMA. 2014 Nat Neurosci
Human Lymphoid Development in the Absence of Common gamma-Chain Receptor Signaling. 2014 J Immunol
HIPPO pathway members restrict SOX2 to the inner cell mass where it promotes ICM fates in the mouse blastocyst. 2014 PLoS Genet
A long noncoding RNA protects the heart from pathological hypertrophy. 2014 Nature
Utilizing Stem Cell-Derived RPE Cells as A Therapeutic Intervention for Age-Related Macular Degeneration. 2014 Adv Exp Med Biol
Positron emission tomography probe demonstrates a striking concentration of ribose salvage in the liver. 2014 Proc Natl Acad Sci U S A
Molecular profiling of premalignant lesions in lung squamous cell carcinomas identifies mechanisms involved in stepwise carcinogenesis. 2014 Cancer Prev Res (Phila)
Human Neural Stem Cells Survive Long Term in the Midbrain of Dopamine-Depleted Monkeys After GDNF Overexpression and Project Neurites Toward an Appropriate Target. 2014 Stem Cells Transl Med
Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells. 2014 J Vis Exp
Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. 2014 Nat Commun
Two miRNA Clusters Reveal Alternative Paths in Late-Stage Reprogramming. 2014 Cell Stem Cell
Radial glia require PDGFD-PDGFRbeta signalling in human but not mouse neocortex. 2014 Nature
STAT3 Phosphorylation at Tyrosine 705 and Serine 727 Differentially Regulates Mouse ESC Fates. 2014 Stem Cells
Discovery of consensus gene signature and intermodular connectivity defining self-renewal of human embryonic stem cells. 2014 Stem Cells
The past, present and future of stem cell clinical trials for ALS. 2014 Exp Neurol
m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. 2014 Cell Stem Cell
Enhanced Genetic Modification of Adult Growth Factor Mobilized Peripheral Blood Hematopoietic Stem and Progenitor Cells With Rapamycin. 2014 Stem Cells Transl Med
Human neural precursor cells promote neurologic recovery in a viral model of multiple sclerosis. 2014 Stem Cell Reports
Somatic correction of junctional epidermolysis bullosa by a highly recombinogenic AAV variant. 2014 Mol Ther
Human embryonic stem cell derived islet progenitors mature inside an encapsulation device without evidence of increased biomass or cell escape. 2014 Stem Cell Res
Reprogramming Human Retinal Pigmented Epithelial Cells to Neurons Using Recombinant Proteins. 2014 Stem Cells Transl Med
Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. 2014 Nat Immunol
Recombinase-Mediated Reprogramming and Dystrophin Gene Addition in mdx Mouse Induced Pluripotent Stem Cells. 2014 PLoS One
Shaking up the salt and pepper: origins of cellular heterogeneity in the inner cell mass of the blastocyst. 2014 EMBO J
Defining the role of oxygen tension in human neural progenitor fate. 2014 Stem Cell Reports
Moving beyond surrogate endpoints in cell therapy trials for heart disease. 2014 Stem Cells Transl Med
Preleukemic mutations in human acute myeloid leukemia affect epigenetic regulators and persist in remission. 2014 Proc Natl Acad Sci U S A
Patient-Specific Induced Pluripotent Stem Cell Models: Generation and Characterization of Cardiac Cells. 2014 Methods Mol Biol
Systematic Identification of Barriers to Human iPSC Generation. 2014 Cell
Dynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study. 2014 Cell Stem Cell
Human neural progenitor cells generated from induced pluripotent stem cells can survive, migrate, and integrate in the rodent spinal cord. 2014 J Comp Neurol
Interventional Magnetic Resonance Imaging-Guided Cell Transplantation into the Brain with Radially Branched Deployment. 2014 Mol Ther
(19)F spin-lattice relaxation of perfluoropolyethers: Dependence on temperature and magnetic field strength (7.0-14.1T). 2014 J Magn Reson
Genome wide profiling of dopaminergic neurons derived from human embryonic and induced pluripotent stem cells. 2014 Stem Cells Dev
Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4. 2014 Cell Rep
Subventricular spread of diffuse intrinsic pontine glioma. 2014 Acta Neuropathol
Single-molecule super-resolution light-sheet microscopy. 2014 Chemphyschem
Reliable Generation of Induced Pluripotent Stem Cells From Human Lymphoblastoid Cell Lines. 2014 Stem Cells Transl Med
Neural stem cells improve intracranial nanoparticle retention and tumor-selective distribution. 2014 Future Oncol
The WNT receptor FZD7 is required for maintenance of the pluripotent state in human embryonic stem cells. 2014 Proc Natl Acad Sci U S A
Upregulation of CD11A on Hematopoietic Stem Cells Denotes the Loss of Long-Term Reconstitution Potential. 2014 Stem Cell Reports
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain. 2014 Science
Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency. 2014 Elife
Human neural stem cells improve cognition and promote synaptic growth in two complementary transgenic models of Alzheimer's disease and neuronal loss. 2014 Hippocampus
The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny. 2014 PLoS One


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