Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
aSIRTing Control over Cancer Stem Cells. 2012 Cancer Cell
Epigenetic regulation of planarian stem cells by the SET1/MLL family of histone methyltransferases. 2012 Epigenetics
Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair. 2012 J Control Release
Live imaging using adaptive optics with fluorescent protein guide-stars. 2012 Opt Express
Stimulation of histone deacetylase activity by metabolites of intermediary metabolism. 2012 J Biol Chem
Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. 2012 Hum Mol Genet
NOTCH1 signaling promotes human T-cell acute lymphoblastic leukemia initiating cell regeneration in supportive niches. 2012 PLoS One
Intrinsically determined cell death of developing cortical interneurons. 2012 Nature
TPP1 OB-Fold Domain Controls Telomere Maintenance by Recruiting Telomerase to Chromosome Ends. 2012 Cell
Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. 2012 J Tissue Eng Regen Med
In utero hematopoietic cell transplantation for the treatment of congenital anomalies. 2012 Clin Perinatol
Induced pluripotent stem cells show metabolomic differences to embryonic stem cells in polyunsaturated phosphatidylcholines and primary metabolism. 2012 PLoS One
Mapping differentiation pathways from hematopoietic stem cells using Flk2/Flt3 lineage tracing. 2012 Cell Cycle
Active chromatin and noncoding RNAs: an intimate relationship. 2012 Curr Opin Genet Dev
Wnt Inhibition Correlates with Human Embryonic Stem Cell Cardiomyogenesis: A Structure-Activity Relationship Study Based on Inhibitors for the Wnt Response. 2012 J Med Chem
Signal-dependent incorporation of MyoD-BAF60c into Brg1-based SWI/SNF chromatin-remodelling complex. 2012 EMBO J
Absence of sclerostin adversely affects B cell survival. 2012 J Bone Miner Res
Endogenous proliferation after spinal cord injury in animal models. 2012 Stem Cells Int
Disruption of NMDA Receptors in Oligodendroglial Lineage Cells Does Not Alter Their Susceptibility to Experimental Autoimmune Encephalomyelitis or Their Normal Development. 2012 J Neurosci
Wnt signaling promotes Muller cell proliferation and survival after injury. 2012 Invest Ophthalmol Vis Sci
Identification of protease exosite-interacting peptides that enhance substrate cleavage kinetics. 2012 Biol Chem
A Lissencephaly-1 homologue is essential for mitotic progression in the planarian Schmidtea mediterranea. 2012 Dev Dyn
Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Cav2.3 calcium channels. 2012 J Gen Physiol
Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells. 2011 Mol Ther
Functional Modules Distinguish Human Induced Pluripotent Stem Cells from Embryonic Stem Cells. 2011 Stem Cells Dev
A role for noncanonical microRNAs in the mammalian brain revealed by phenotypic differences in Dgcr8 versus Dicer1 knockouts and small RNA sequencing. 2011 RNA
GROalpha regulates human embryonic stem cell self-renewal or adoption of a neuronal fate. 2011 Differentiation
miR than meets the eye. 2011 Genes Dev
Evolving concepts in lung carcinogenesis. 2011 Semin Respir Crit Care Med
Induced pluripotent stem cells for neural tissue engineering. 2011 Biomaterials
Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells. 2011 Proc Natl Acad Sci U S A
Beyond Phenotype: The Promise of hiPSC-Based Studies of Schizophrenia. 2011 Stem Cells
Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. 2011 Nature
Self-renewal induced efficiently, safely, and effective therapeutically with one regulatable gene in a human somatic progenitor cell. 2011 Proc Natl Acad Sci U S A
Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility. 2011 Hum Mol Genet
Decellularized liver matrix as a carrier for the transplantation of human fetal and primary hepatocytes in mice. 2011 Liver Transpl
In vivo demonstration that {alpha}-synuclein oligomers are toxic. 2011 Proc Natl Acad Sci U S A
Neuropilins are positive regulators of Hedgehog signal transduction. 2011 Genes Dev
Defining the nature of human pluripotent stem cell progeny. 2011 Cell Res
Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence. 2011 PLoS One
MHC Mismatch Inhibits Neurogenesis and Neuron Maturation in Stem Cell Allografts. 2011 PLoS One
Endothelial cells from embryonic stem cells in a chemically defined medium. 2011 Stem Cells Dev
In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases. 2011 Stem Cells
Characterization of high-affinity peptides and their feasibility for use in nanotherapeutics targeting leukemia stem cells. 2011 Nanomedicine
Transcriptomic Signature of Trophoblast Differentiation in a Human Embryonic Stem Cell Model. 2011 Biol Reprod
Mitochondrial cardiomyopathies: how to identify candidate pathogenic mutations by mitochondrial DNA sequencing, MITOMASTER and phylogeny. 2011 Eur J Hum Genet
Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. 2011 J Hepatol
A New FACS Approach Isolates hESC Derived Endoderm Using Transcription Factors. 2011 PLoS One
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. 2011 Nat Biotechnol
Critical role of PINK1 in regulating Parkin protein levels in vivo. 2011 Arch Neurol


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