Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Endogenous Wnt signalling in human embryonic stem cells generates an equilibrium of distinct lineage-specified progenitors. 2012 Nat Commun
Human ESC Self-Renewal Promoting miRNAs Induce Epithelial-Mesenchymal Transition in Hepatocytes by Controlling the PTEN and TGFbeta Tumor Suppressor Signaling Pathways. 2012 Mol Cancer Res
Exogenous Activation of BMP-2 Signaling Overcomes TGFbeta-Mediated Inhibition of Osteogenesis in Marfan Embryonic Stem Cells and Marfan Patient-Specific Induced Pluripotent Stem Cells. 2012 Stem Cells
The genomic stability of induced pluripotent stem cells. 2012 Protein Cell
Wnt Signaling and Injury Repair. 2012 Cold Spring Harb Perspect Biol
Correcting human mitochondrial mutations with targeted RNA import. 2012 Proc Natl Acad Sci U S A
The little molecules that could: a story about microRNAs in neural stem cells and neurogenesis. 2012 Front Neurosci
Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest. 2012 Cell Stem Cell
The effect of stromal cell-derived factor-1alpha/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration. 2012 Biomaterials
Biophysical regulation of stem cell behavior within the niche. 2012 Stem Cell Res Ther
Cholangiocarcinomas can originate from hepatocytes in mice. 2012 J Clin Invest
Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. 2012 PLoS One
The many roads to Rome: induction of neural precursor cells from fibroblasts. 2012 Curr Opin Genet Dev
miR-125b Promotes Early Germ Layer Specification through Lin28/let-7d and Preferential Differentiation of Mesoderm in Human Embryonic Stem Cells. 2012 PLoS One
Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. 2012 Cell
The GLIB technique for genome-wide mapping of 5-hydroxymethylcytosine. 2012 Nat Protoc
NELL-1 Injection Maintains Long Bone Quantity and Quality in an Ovariectomy-Induced Osteoporotic Senile Rat Model. 2012 Tissue Eng Part A
Modeling Parkinson's disease using induced pluripotent stem cells. 2012 Curr Neurol Neurosci Rep
Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells. 2012 PLoS One
Rapid fibroblast removal from high density human embryonic stem cell cultures. 2012 J Vis Exp
Sox1 marks an activated neural stem/progenitor cell in the hippocampus. 2012 Development
Sinus microbiome diversity depletion and Corynebacterium tuberculostearicum enrichment mediates rhinosinusitis. 2012 Sci Transl Med
Heterochronic parabiosis for the study of the effects of aging on stem cells and their niches. 2012 Cell Cycle
A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal. 2012 Integr Biol (Camb)
From skin biopsy to neurons through a pluripotent intermediate under good manufacturing practice protocols. 2012 Stem Cells Transl Med
Concise review: Immune recognition of induced pluripotent stem cells. 2012 Stem Cells
Modeling neurodevelopmental disorders using human neurons. 2012 Curr Opin Neurobiol
Use of LysoTracker to detect programmed cell death in embryos and differentiating embryonic stem cells. 2012 J Vis Exp
Smyd3 regulates cancer cell phenotypes and catalyzes histone H4 lysine 5 methylation. 2012 Epigenetics
The emerging functions of the p53-miRNA network in stem cell biology. 2012 Cell Cycle
Using the BLT Humanized Mouse as a Stem Cell based Gene Therapy Tumor Model. 2012 J Vis Exp
APJ acts as a dual receptor in cardiac hypertrophy. 2012 Nature
Rapid and cost-effective gene targeting in rat embryonic stem cells by TALENs. 2012 J Genet Genomics
Modeling psychiatric disorders at the cellular and network levels. 2012 Mol Psychiatry
Zebrafish screen identifies novel compound with selective toxicity against leukemia. 2012 Blood
SRY-box-containing gene 2 regulation of nuclear receptor tailless (Tlx) transcription in adult neural stem cells. 2012 J Biol Chem
Single-injection HPLC method for rapid analysis of a combination drug delivery system. 2012 AAPS PharmSciTech
Effective delivery of stem cells using an extracellular matrix patch results in increased cell survival and proliferation and reduced scarring in skin wound healing. 2012 Tissue Eng Part A
Nodal signaling regulates endodermal cell motility and actin dynamics via Rac1 and Prex1. 2012 J Cell Biol
Advances in treatment and management: immunologic and cell-based regenerative therapies. 2012 Invest Ophthalmol Vis Sci
Dynamic expression of the Robo ligand Slit2 in bone marrow cell populations. 2012 Cell Cycle
Phasor Fluorescence Lifetime Microscopy of Free and Protein-Bound NADH Reveals Neural Stem Cell Differentiation Potential. 2012 PLoS One
Astrocytes regulate adult hippocampal neurogenesis through ephrin-B signaling. 2012 Nat Neurosci
Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop. 2012 Genes Dev
Library-free methylation sequencing with bisulfite padlock probes. 2012 Nat Methods
Isolation and in vitro characterization of Basal and submucosal gland duct stem/progenitor cells from human proximal airways. 2012 Stem Cells Transl Med
Challenges to the clinical application of pluripotent stem cells: towards genomic and functional stability. 2012 Genome Med
Dnmt3a regulates both proliferation and differentiation of mouse neural stem cells. 2012 J Neurosci Res
Characterizing the radioresponse of pluripotent and multipotent human stem cells. 2012 PLoS One
Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. 2012 Cell Stem Cell


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