[(18)F]FDG-PET and [(18)F]MPPF-PET are brain biomarkers for the creatine transporter Slc6a8 loss of function mutation. |
2025 |
Sci Rep |
Acholinebio-ionicliquid-functionalized gelatin methacryloyl hydrogel for chronic wound healing |
2025 |
European Polymer Journal |
Adipose tissue ageing: implications for metabolic health and lifespan. |
2025 |
Nat Rev Endocrinol |
ADMET-AI Enables Interpretable Predictions of Drug-Induced Cardiotoxicity. |
2025 |
Circulation |
Allogeneic CD33-directed CAR-NKT cells for the treatment of bone marrow-resident myeloid malignancies. |
2025 |
Nat Commun |
An SSTR2-somatostatin chemotactic axis drives T cell progenitor homing to the intestines. |
2025 |
Nat Immunol |
Biological tendon regeneration, are we almost there or is it still a stretch? |
2025 |
Regen Med |
Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork. |
2025 |
Transl Vis Sci Technol |
Derivation and Characterization of Isogenic OPA1 Mutant and Control Human Pluripotent Stem Cell Lines. |
2025 |
Cells |
Distinct adipose progenitor cells emerging with age drive active adipogenesis. |
2025 |
Science |
Distinct molecular patterns in R6/2 HD mouse brain: Insights from spatiotemporal transcriptomics. |
2025 |
Neuron |
Dosing parameters for grafting human neural stem cells into sites of spinal cord injury. |
2025 |
Exp Neurol |
Double-strand break repair pathways differentially affect processing and transduction by dual AAV vectors. |
2025 |
Nat Commun |
Effect of immunosuppression on hESC-derived retina organoids in vitro and in vivo. |
2025 |
Stem Cell Res Ther |
Efficient Retroviral Transduction and Competitive Homing for Investigating GPCR-Mediated T-Cell Localization in Diverse Tissue Microenvironments. |
2025 |
J Vis Exp |
eIF3 engages with 3′-UTR termini of highly translated mRNAs. |
2025 |
Elife |
Elevated Senescence Markers in Developing Trisomy 21 Human Lungs. |
2025 |
Am J Respir Cell Mol Biol |
Epigenetic Upregulation of Carotid Body Angiotensin Signaling Increases Blood Pressure. |
2025 |
Hypertension |
Every cell every gene all at once: Systems genetic approaches toward corticogenesis. |
2025 |
Curr Opin Neurobiol |
Evidence of neuronal DNA damage in the brains of patients with Rett syndrome. |
2025 |
Dis Model Mech |
Evolving CAR T-Cell Therapy to Overcome the Barriers in Treating Pediatric Central Nervous System Tumors. |
2025 |
Cancer Discov |
Functional Neurogenomics to Dissect Disease Mechanisms Across Models. |
2025 |
Annu Rev Genomics Hum Genet |
FXYD2 marks and regulates maturity of beta cells via ion channel-mediated signal transduction. |
2025 |
Nat Commun |
Generating allogeneic CAR-NKT cells for off-the-shelf cancer immunotherapy with genetically engineered HSP cells and feeder-free differentiation culture. |
2025 |
Nat Protoc |
Generation of a set of genetically modified long QT syndrome induced pluripotent stem cell lines carrying knock-in variants rs120074178 (KCNQ1 c.569G > A; p.Arg190Gln) and rs137854600 (SCN5A c.4865G > A; p.Arg1622Gln) and isogenic control lines. |
2025 |
Stem Cell Res |
Genome editing with programmable base editors in human cells. |
2025 |
Methods Enzymol |
Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate. |
2025 |
Genes Dev |
Identification of novel genetic mutations for the treatment prognostication of canine lymphoma. |
2025 |
NPJ Precis Oncol |
Implantation of engineered adipocytes suppresses tumor progression in cancer models. |
2025 |
Nat Biotechnol |
Lysosomal proteomics reveals mechanisms of neuronal apoE4-associated lysosomal dysfunction. |
2025 |
bioRxiv |
Minimally invasive serial collection of cerebrospinal fluid reveals sex-dependent differences in neuroinflammation in a rat model of mild traumatic brain injury. |
2025 |
Brain Behav Immun |
On the Feasibility of SERS-Based Monitoring of Drug Loading Efficiency in Exosomes for Targeted Delivery. |
2025 |
Biosensors (Basel) |
Rapamycin enhances CAR-T control of HIV replication and reservoir elimination in vivo. |
2025 |
J Clin Invest |
Reversible proliferative arrest induced by rapid depletion of RNase MRP. |
2025 |
Nat Commun |
Spinal Cord Injury in Real Time: Intra-Operative Ultrasound for Acute Phase Examination in Non-Human Primates. |
2025 |
Brain Sci |
Structural and functional analysis of cancer-associated missense variants in the retinoblastoma protein pocket domain. |
2025 |
J Biol Chem |
Suppressing APOE4-induced neural pathologies by targeting the VHL-HIF axis. |
2025 |
Proc Natl Acad Sci U S A |
The UCSC Genome Browser database: 2025 update. |
2025 |
Nucleic Acids Res |
Upregulated FoxO1 promotes arrhythmogenesis in mice with heart failure and preserved ejection fraction. |
2025 |
Nat Commun |
A CD38-directed, single-chain T-cell engager targets leukemia stem cells through IFN-gamma-induced CD38 expression. |
2024 |
Blood |
A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis. |
2024 |
Elife |
A facilitatory role of astrocytes in axonal regeneration after acute and chronic spinal cord injury. |
2024 |
Exp Neurol |
A fibroblast-dependent TGF-beta1/sFRP2 noncanonical Wnt signaling axis promotes epithelial metaplasia in idiopathic pulmonary fibrosis. |
2024 |
J Clin Invest |
A framework for N-of-1 trials of individualized gene-targeted therapies for genetic diseases. |
2024 |
Nat Commun |
A lymphocyte chemoaffinity axis for lung, non-intestinal mucosae and CNS. |
2024 |
Nature |
A maternal brain hormone that builds bone. |
2024 |
Nature |
A novel high-titer, bifunctional lentiviral vector for autologous hematopoietic stem cell gene therapy of sickle cell disease. |
2024 |
Mol Ther Methods Clin Dev |
A Panoramic View of Cell Population Dynamics in Mammalian Aging. |
2024 |
bioRxiv |
A therapy for suppressing canonical and noncanonical SARS-CoV-2 viral entry and an intrinsic intrapulmonary inflammatory response. |
2024 |
Proc Natl Acad Sci U S A |
Acid-degradable lipid nanoparticles enhance the delivery of mRNA. |
2024 |
Nat Nanotechnol |