Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
The microRNA cluster miR-106b~25 regulates adult neural stem/progenitor cell proliferation and neuronal differentiation. 2011 Aging (Albany NY)
Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons under Defined Conditions. 2011 Cell Stem Cell
Mechanistic insights into reprogramming to induced pluripotency. 2011 J Cell Physiol
Morphological analysis of CDC2 and glycogen synthase kinase 3beta phosphorylation as markers of g2 --> m transition in glioma. 2011 Patholog Res Int
Germ-layer and lineage-restricted stem/progenitors regenerate the mouse digit tip. 2011 Nature
Embryonic Stem Cell-Derived Hematopoietic Stem Cells: Challenges in Development, Differentiation, and Immunogenicity. 2011 Curr Top Med Chem
Successful Investigational New Drug Preparation without Reinventing the Wheel. 2011 J Invest Dermatol
Modeling initiation of ewing sarcoma in human neural crest cells. 2011 PLoS One
Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. 2011 Dev Biol
Dynamic changes in the copy number of pluripotency and cell proliferation genes in human ESCs and iPSCs during reprogramming and time in culture. 2011 Cell Stem Cell
Rapid mRNA-Display Selection of an IL-6 Inhibitor Using Continuous-Flow Magnetic Separation. 2011 Angew Chem Int Ed Engl
HEB and E2A function as SMAD/FOXH1 cofactors. 2011 Genes Dev
Quantitative assessment of immune cells in the injured spinal cord tissue by flow cytometry: a novel use for a cell purification method. 2011 J Vis Exp
Direct reprogramming of mouse fibroblasts to neural progenitors. 2011 Proc Natl Acad Sci U S A
A New FACS Approach Isolates hESC Derived Endoderm Using Transcription Factors. 2011 PLoS One
Dorsomorphin Promotes Human Embryonic Stem Cell Self-Renewal. 2011 Angew Chem Int Ed Engl
Regulation of tooth number by fine-tuning levels of receptor-tyrosine kinase signaling. 2011 Development
Generation of HIV-1 Resistant and Functional Macrophages From Hematopoietic Stem Cell-derived Induced Pluripotent Stem Cells. 2011 Mol Ther
Progress in understanding reprogramming to the induced pluripotent state. 2011 Nat Rev Genet
Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. 2011 Science
Multi-Dimensional X-Space Magnetic Particle Imaging. 2011 IEEE Trans Med Imaging
The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-beta. 2011 Biomaterials
Rapid induction and long-term self-renewal of primitive neural precursors from human embryonic stem cells by small molecule inhibitors. 2011 Proc Natl Acad Sci U S A
MR-based keyhole SPECT for small animal imaging. 2011 Phys Med Biol
Computer-Aided 2D and 3D quantification of human stem cell fate from in vitro samples using Volocity high performance image analysis software. 2011 Stem Cell Res
New Approaches in the Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells toward Hepatocytes. 2011 Stem Cell Rev
3D-Spheroid Culture of Human Gingiva-Derived Mesenchymal Stem Cells Enhances Mitigation of Chemotherapy-Induced Oral Mucositis. 2011 Stem Cells Dev
NANOS3 function in human germ cell development. 2011 Hum Mol Genet
High Throughput MicroRNA Profiling: Optimized Multiplex qRT-PCR at Nanoliter Scale on the Fluidigm Dynamic ArrayTM IFCs. 2011 J Vis Exp
Overexpression of BCL2 enhances survival of human embryonic stem cells during stress and obviates the requirement for serum factors. 2011 Proc Natl Acad Sci U S A
A Slit/miR-218/Robo regulatory loop is required during heart tube formation in zebrafish. 2011 Development
Partial pneumonectomy of telomerase null mice carrying shortened telomeres initiates cell growth arrest resulting in a limited compensatory growth response. 2011 Am J Physiol Lung Cell Mol Physiol
Mitochondrial cardiomyopathies: how to identify candidate pathogenic mutations by mitochondrial DNA sequencing, MITOMASTER and phylogeny. 2011 Eur J Hum Genet
Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium. 2011 Development
Characterization of an In Vitro Differentiation Assay for Pancreatic-Like Cell Development from Murine Embryonic Stem Cells: Detailed Gene Expression Analysis. 2011 Assay Drug Dev Technol
Optogenetics in neural systems. 2011 Neuron
Genetically Encoding Unnatural Amino Acids in Neural Stem Cells and Optically Reporting Voltage-Sensitive Domain Changes in Differentiated Neurons. 2011 Stem Cells
Gene Editing of Human Embryonic Stem Cells via an Engineered Baculoviral Vector Carrying Zinc-finger Nucleases. 2011 Mol Ther
A Novel Stem/Progenitor Cell Population from Murine Tracheal Submucosal Gland Ducts with Multipotent Regenerative Potential. 2011 Stem Cells
Retinoic Acid functions as a key GABAergic differentiation signal in the Basal Ganglia. 2011 PLoS Biol
From microRNAs to targets: pathway discovery in cell fate transitions. 2011 Curr Opin Genet Dev
Mesenchymal-Specific Inhibition of Vascular Endothelial Growth Factor (VEGF) Attenuates Growth in Neonatal Mice. 2011 J Surg Res
Myo-mechanical analysis of isolated skeletal muscle. 2011 J Vis Exp
Deep Sequencing Reveals Novel MicroRNAs and Regulation of MicroRNA Expression during Cell Senescence. 2011 PLoS One
MHC Mismatch Inhibits Neurogenesis and Neuron Maturation in Stem Cell Allografts. 2011 PLoS One
Engineered polymer-media interfaces for the long-term self-renewal of human embryonic stem cells. 2011 Biomaterials
Adaptive optics wide-field microscopy using direct wavefront sensing. 2011 Opt Lett
Induced pluripotent stem cells for neural tissue engineering. 2011 Biomaterials
Computational integration of homolog and pathway gene module expression reveals general stemness signatures. 2011 PLoS One
Reprogramming to pluripotency: stepwise resetting of the epigenetic landscape. 2011 Cell Res

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