Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Stereochemical basis for engineered pyrrolysyl-tRNA synthetase and the efficient in vivo incorporation of structurally divergent non-native amino acids. 2011 ACS Chem Biol
Stepwise chemically induced cardiomyocyte specification of human embryonic stem cells. 2011 Angew Chem Int Ed Engl
Placental expression of vascular endothelial growth factor receptor-1/soluble vascular endothelial growth factor receptor-1 correlates with severity of clinical preeclampsia and villous hypermaturity. 2011 Hum Pathol
Macroglial plasticity and the origins of reactive astroglia in experimental autoimmune encephalomyelitis. 2011 J Neurosci
Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes. 2011 J Mammary Gland Biol Neoplasia
MEF2C Enhances Dopaminergic Neuron Differentiation of Human Embryonic Stem Cells in a Parkinsonian Rat Model. 2011 PLoS One
Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members. 2011 PLoS One
Inhibitors of tyrosine phosphatases and apoptosis reprogram lineage-marked differentiated muscle to myogenic progenitor cells. 2011 Chem Biol
CXCR4 signaling regulates remyelination by endogenous oligodendrocyte progenitor cells in a viral model of demyelination. 2011 Glia
Nanogel star polymer architectures: a nanoparticle platform for modular programmable macromolecular self-assembly, intercellular transport, and dual-mode cargo delivery. 2011 Adv Mater
PDGF enhances store-operated Ca2+ entry by upregulating STIM1/Orai1 via activation of Akt/mTOR in human pulmonary arterial smooth muscle cells. 2011 Am J Physiol Cell Physiol
GROalpha regulates human embryonic stem cell self-renewal or adoption of a neuronal fate. 2011 Differentiation
Measurement of bioelectric current with a vibrating probe. 2011 J Vis Exp
Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells. 2011 Proc Natl Acad Sci U S A
The post-apoptotic fate of RNAs identified through high-throughput sequencing of human hair. 2011 PLoS One
Modulation of Longevity and Tissue Homeostasis by the Drosophila PGC-1 Homolog. 2011 Cell Metab
The ageing systemic milieu negatively regulates neurogenesis and cognitive function. 2011 Nature
Identification of the earliest natural killer cell committed progenitor in murine bone marrow. 2011 Blood
LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans. 2011 Nat Struct Mol Biol
Uniaxial mechanical strain modulates the differentiation of neural crest stem cells into smooth muscle lineage on micropatterned surfaces. 2011 PLoS One
Modeling psychiatric disorders through reprogramming. 2011 Dis Model Mech
Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. 2011 J Hepatol
Mediator coordinates PIC assembly with recruitment of CHD1. 2011 Genes Dev
Mesenchymal stem cell-based tissue regeneration is governed by recipient T lymphocytes via IFN-gamma and TNF-alpha 2011 Nat Med
Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming. 2011 Cell Stem Cell
The maternal immune response inhibits the success of in utero hematopoietic cell transplantation. 2011 Chimerism
RF1 knockout allows ribosomal incorporation of unnatural amino acids at multiple sites. 2011 Nat Chem Biol
Notch post-translationally regulates beta-catenin protein in stem and progenitor cells. 2011 Nat Cell Biol
The role of anti-mullerian hormone (AMH) in assessing ovarian reserve. 2011 J Clin Endocrinol Metab
Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRTdeficient bone marrow. 2011 Exp Hematol
Vitamin C treatment promotes mesenchymal stem cell sheet formation and tissue regeneration by elevating telomerase activity. 2011 J Cell Physiol
Divergent RNA-Binding Proteins, DAZL and VASA, Induce Meiotic Progression in Human Germ Cells Derived In vitro. 2011 Stem Cells
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. 2011 EMBO J
Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. 2011 Proc Natl Acad Sci U S A
VEGF optimizes the formation of tissue-engineered small intestine. 2011 Regen Med
Control of Embryonic Stem Cell Lineage Commitment by Core Promoter Factor, TAF3. 2011 Cell
Decreased Risk of Graft Failure with Maternal Liver Transplantation in Patients with Biliary Atresia. 2011 Am J Transplant
Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells. 2011 Nature
Endogenous APOBEC3B restricts LINE-1 retrotransposition in transformed cells and human embryonic stem cells. 2011 J Biol Chem
Derivation of Smooth Muscle Cells with Neural Crest Origin from Human Induced Pluripotent Stem Cells. 2011 Cells Tissues Organs
Identification of multipotent stem/progenitor cells in murine sclera. 2011 Invest Ophthalmol Vis Sci
Characterization of a novel angiogenic model based on stable, fluorescently labeled endothelial cell lines amenable to scale-up for high content screening. 2011 Biol Cell
Genetically Engineered Mesenchymal Stem Cells as a Proposed Therapeutic for Huntington's Disease. 2011 Mol Neurobiol
The intestinal stem cell markers Bmi1 and Lgr5 identify two functionally distinct populations. 2011 Proc Natl Acad Sci U S A
Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. 2011 Genes Dev
Mesenchymal-Specific Inhibition of Vascular Endothelial Growth Factor (VEGF) Attenuates Growth in Neonatal Mice. 2011 J Surg Res
Myelin Restoration: Progress and Prospects for Human Cell Replacement Therapies. 2011 Arch Immunol Ther Exp (Warsz)
Myo-mechanical analysis of isolated skeletal muscle. 2011 J Vis Exp
Embryonic anti-aging niche. 2011 Aging (Albany NY)
Engineered polymer-media interfaces for the long-term self-renewal of human embryonic stem cells. 2011 Biomaterials

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