Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Mapping human epigenomes. 2013 Cell
Oct4 Cell-Autonomously Promotes Primitive Endoderm Development in the Mouse Blastocyst. 2013 Dev Cell
Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice. 2013 J Infect Dis
Functional assessment of long-term deficits in rodent models of traumatic brain injury. 2013 Regen Med
Linearity and shift invariance for quantitative magnetic particle imaging. 2013 IEEE Trans Med Imaging
Insulin and IGFs Enhance Hepatocyte Differentiation from Human Embryonic Stem Cells via the PI3K/AKT Pathway. 2013 Stem Cells
The Presenilin-1 DeltaE9 Mutation Results in Reduced gamma-Secretase Activity, but Not Total Loss of PS1 Function, in Isogenic Human Stem Cells. 2013 Cell Rep
Preferential biological processes in the human limbus by differential gene profiling. 2013 PLoS One
Generation and characterization of transgene-free human induced pluripotent stem cells and conversion to putative clinical-grade status. 2013 Stem Cell Res Ther
Melanocytes derived from transgene-free human induced pluripotent stem cells. 2013 J Invest Dermatol
Loss of survivin in the prostate epithelium impedes carcinogenesis in a mouse model of prostate adenocarcinoma. 2013 PLoS One
Ebf1 and c-Myb repress rag transcription downstream of Stat5 during early B cell development. 2013 J Immunol
Missense Mutations in Plakophilin-2 Cause Sodium Current Deficit and Associate with a Brugada Syndrome Phenotype. 2013 Circulation
ECM-dependent HIF induction directs trophoblast stem cell fate via LIMK1-mediated cytoskeletal rearrangement. 2013 PLoS One
Synthesis of a photocaged tamoxifen for light-dependent activation of Cre-ER recombinase-driven gene modification. 2013 Chem Commun (Camb)
Do pluripotent stem cells exist in adult mice as very small embryonic stem cells? 2013 Stem Cell Reports
Small molecule screening with laser cytometry can be used to identify pro-survival molecules in human embryonic stem cells. 2013 PLoS One
Methods to quantify microRNAs in the Myc gene network for posttranscriptional gene repression. 2013 Methods Mol Biol
Particle shape enhances specificity of antibody-displaying nanoparticles. 2013 Proc Natl Acad Sci U S A
Genome-wide approaches to dissect the roles of RNA binding proteins in translational control: implications for neurological diseases. 2012 Front Neurosci
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. 2012 Cell Res
High-Frequency Hippocampal Oscillations Activated by Optogenetic Stimulation of Transplanted Human ESC-Derived Neurons. 2012 J Neurosci
Brief report: Mechanism of extravasation of infused stem cells. 2012 Stem Cells
Mixed results for bone marrow-derived cell therapy for ischemic heart disease. 2012 JAMA
Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via beta-catenin signaling. 2012 Genes Dev
Adoptive transfer of induced-treg cells effectively attenuates murine airway allergic inflammation. 2012 PLoS One
Active chromatin and noncoding RNAs: an intimate relationship. 2012 Curr Opin Genet Dev
Wnt Inhibition Correlates with Human Embryonic Stem Cell Cardiomyogenesis: A Structure-Activity Relationship Study Based on Inhibitors for the Wnt Response. 2012 J Med Chem
From skin biopsy to neurons through a pluripotent intermediate under good manufacturing practice protocols. 2012 Stem Cells Transl Med
Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal. 2012 Cell Stem Cell
Stage-Specific Cardiomyocyte Differentiation Method for H7 and H9 Human Embryonic Stem Cells. 2012 Stem Cell Rev
Absence of sclerostin adversely affects B cell survival. 2012 J Bone Miner Res
Disruption of NMDA Receptors in Oligodendroglial Lineage Cells Does Not Alter Their Susceptibility to Experimental Autoimmune Encephalomyelitis or Their Normal Development. 2012 J Neurosci
The little molecules that could: a story about microRNAs in neural stem cells and neurogenesis. 2012 Front Neurosci
Molecular roadblocks for cellular reprogramming. 2012 Mol Cell
Widespread dynamic DNA methylation in response to biotic stress. 2012 Proc Natl Acad Sci U S A
aSIRTing Control over Cancer Stem Cells. 2012 Cancer Cell
Fibroblast growth factor 10-fibroblast growth factor receptor 2b mediated signaling is not required for adult glandular stomach homeostasis. 2012 PLoS One
TCF/LEFs and Wnt Signaling in the Nucleus. 2012 Cold Spring Harb Perspect Biol
Mineralized Synthetic Matrices as an Instructive Microenvironment for Osteogenic Differentiation of Human Mesenchymal Stem Cells. 2012 Macromol Biosci
Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. 2012 Hum Mol Genet
Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. 2012 Cell
Impaired placental nutrient transport in mice generated by in vitro fertilization. 2012 Endocrinology
Electrical signaling in control of ocular cell behaviors. 2012 Prog Retin Eye Res
Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes. 2012 Cell Stem Cell
Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. 2012 J Tissue Eng Regen Med
Patient-specific induced pluripotent stem cells as a model for familial dilated cardiomyopathy. 2012 Sci Transl Med
Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche. 2012 Cell Rep
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. 2012 Am J Physiol Lung Cell Mol Physiol
Chromatin Isolation by RNA Purification (ChIRP). 2012 J Vis Exp

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