Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Stereochemical basis for engineered pyrrolysyl-tRNA synthetase and the efficient in vivo incorporation of structurally divergent non-native amino acids. 2011 ACS Chem Biol
Multiscale computational models for optogenetic control of cardiac function. 2011 Biophys J
miR-34 miRNAs provide a barrier for somatic cell reprogramming. 2011 Nat Cell Biol
Myc and Miz-1 have coordinate genomic functions including targeting Hox genes in human embryonic stem cells. 2011 Epigenetics Chromatin
SNCA Triplication Parkinson's Patient's iPSC-derived DA Neurons Accumulate alpha-Synuclein and Are Susceptible to Oxidative Stress. 2011 PLoS One
MicroRNA programs in normal and aberrant stem and progenitor cells. 2011 Genome Res
Navigating breast cancer: axon guidance molecules as breast cancer tumor suppressors and oncogenes. 2011 J Mammary Gland Biol Neoplasia
Molecular Mechanisms of Long Noncoding RNAs. 2011 Mol Cell
Human Embryonic Stem Cells Express Elevated Levels of Multiple Pro-Apoptotic BCL-2 Family Members. 2011 PLoS One
Electrophysiological Mapping of Embryonic Mouse Hearts: Mechanisms for Developmental Pacemaker Switch and Internodal Conduction Pathway. 2011 J Cardiovasc Electrophysiol
Stepwise chemically induced cardiomyocyte specification of human embryonic stem cells. 2011 Angew Chem Int Ed Engl
Inducing iPSCs to escape the dish. 2011 Cell Stem Cell
Stem cell gene expression programs influence clinical outcome in human leukemia. 2011 Nat Med
GROalpha regulates human embryonic stem cell self-renewal or adoption of a neuronal fate. 2011 Differentiation
Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells. 2011 Proc Natl Acad Sci U S A
Beyond Phenotype: The Promise of hiPSC-Based Studies of Schizophrenia. 2011 Stem Cells
The post-apoptotic fate of RNAs identified through high-throughput sequencing of human hair. 2011 PLoS One
Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility. 2011 Hum Mol Genet
Neuropilins are positive regulators of Hedgehog signal transduction. 2011 Genes Dev
Nanogel star polymer architectures: a nanoparticle platform for modular programmable macromolecular self-assembly, intercellular transport, and dual-mode cargo delivery. 2011 Adv Mater
Directed Evolution of Adeno-associated Virus for Enhanced Gene Delivery and Gene Targeting in Human Pluripotent Stem Cells. 2011 Mol Ther
Functional Modules Distinguish Human Induced Pluripotent Stem Cells from Embryonic Stem Cells. 2011 Stem Cells Dev
Epithelial mesenchymal transition and hedgehog signaling activation are associated with chemoresistance and invasion of hepatoma subpopulations. 2011 J Hepatol
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. 2011 Nat Biotechnol
Mediator coordinates PIC assembly with recruitment of CHD1. 2011 Genes Dev
A Chemical Approach to Controlling Cell Fate and Function. 2011 Stem Cells
Akt increases sox2 expression in adult hippocampal neural progenitor cells, but increased sox2 does not promote proliferation. 2011 Stem Cells Dev
miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. 2011 Nat Commun
Double Edge: CDK2AP1 in Cell-cycle Regulation and Epigenetic Regulation. 2011 J Dent Res
Endothelial cells from embryonic stem cells in a chemically defined medium. 2011 Stem Cells Dev
In Situ Genetic Correction of the Sickle Cell Anemia Mutation in Human Induced Pluripotent Stem Cells Using Engineered Zinc Finger Nucleases. 2011 Stem Cells
Site-Specific Recombinase Strategy to create iPS Cells Efficiently with Plasmid DNA. 2011 Stem Cells
Vitamin C treatment promotes mesenchymal stem cell sheet formation and tissue regeneration by elevating telomerase activity. 2011 J Cell Physiol
Divergent RNA-Binding Proteins, DAZL and VASA, Induce Meiotic Progression in Human Germ Cells Derived In vitro. 2011 Stem Cells
Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis. 2011 Cell Res
Ataxia telangiectasia mutated (ATM) modulates long interspersed element-1 (L1) retrotransposition in human neural stem cells. 2011 Proc Natl Acad Sci U S A
VEGF optimizes the formation of tissue-engineered small intestine. 2011 Regen Med
Genome sequencing of mouse induced pluripotent stem cells reveals retroelement stability and infrequent DNA rearrangement during reprogramming. 2011 Cell Stem Cell
The maternal immune response inhibits the success of in utero hematopoietic cell transplantation. 2011 Chimerism
Id3 upregulates BrdU incorporation associated with a DNA damage response, not replication, in human pancreatic beta-cells. 2011 Islets
Roles of Hedgehog pathway components and retinoic acid signalling in specifying zebrafish ventral spinal cord neurons. 2011 Development
Improving Aptamer Selection Efficiency through Volume Dilution, Magnetic Concentration, and Continuous Washing in Microfluidic Channels. 2011 Anal Chem
The role of anti-mullerian hormone (AMH) in assessing ovarian reserve. 2011 J Clin Endocrinol Metab
Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. 2011 J Clin Invest
Self-organizing and stochastic behaviors during the regeneration of hair stem cells. 2011 Science
Improved engraftment with minimal graft-versus-host disease after major histocompatibility complex-mismatched cord blood transplantation with photochemically treated donor lymphocytes. 2011 Exp Biol Med (Maywood)
Oct4 kinetics predict cell lineage patterning in the early mammalian embryo. 2011 Nat Cell Biol
Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells. 2011 Nature
BCL6 enables Ph(+) acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. 2011 Nature
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal. 2011 Nat Cell Biol


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