Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
DNA methyltransferase-3-dependent nonrandom template segregation in differentiating embryonic stem cells. 2013 J Cell Biol
Myc binds the pluripotency factor Utf1 through the basic-helix-loop-helix leucine zipper domain. 2013 Biochem Biophys Res Commun
Multivalent ligands control stem cell behaviour in vitro and in vivo. 2013 Nat Nanotechnol
Deficiency of MIWI2 (Piwil4) induces mouse erythroleukemia cell differentiation, but has no effect on hematopoiesis in vivo. 2013 PLoS One
TYK2-STAT1-BCL2 Pathway Dependence in T-cell Acute Lymphoblastic Leukemia. 2013 Cancer Discov
Breaking down protein degradation mechanisms in cardiac muscle. 2013 Trends Mol Med
Co-encapsulation of anti-BMP2 monoclonal antibody and mesenchymal stem cells in alginate microspheres for bone tissue engineering. 2013 Biomaterials
From neural development to cognition: unexpected roles for chromatin. 2013 Nat Rev Genet
Proteomic and genomic approaches reveal critical functions of H3K9 methylation and heterochromatin protein-1gamma in reprogramming to pluripotency. 2013 Nat Cell Biol
Introduction of Exogenous T-cell Receptors Into Human Hematopoietic Progenitors Results in Exclusion of Endogenous T-cell Receptor Expression. 2013 Mol Ther
Contextual effect of repression of bone morphogenetic protein activity in prostate cancer. 2013 Endocr Relat Cancer
Headcase promotes cell survival and niche maintenance in the Drosophila testis. 2013 PLoS One
An indirect approach to generating specific human cell types. 2013 Nat Methods
Astroglial cells regulate the developmental timeline of human neurons differentiated from induced pluripotent stem cells. 2013 Stem Cell Res
Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells. 2013 Proc Natl Acad Sci U S A
A Three-Dimensional Culture Method to Expand Limbal Stem/Progenitor Cells. 2013 Tissue Eng Part C Methods
Glial cell line-derived neurotrophic factor-secreting human neural progenitors show long-term survival, maturation into astrocytes, and no tumor formation following transplantation into the spinal cord of immunocompromised rats. 2013 Neuroreport
Placental growth factor expression is required for bone marrow endothelial cell support of primitive murine hematopoietic cells. 2013 PLoS One
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism. 2013 Cell Res
Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation. 2013 Proc Natl Acad Sci U S A
Flk2/Flt3 promotes both myeloid and lymphoid development by expanding non-self-renewing multipotent hematopoietic progenitor cells. 2013 Exp Hematol
Immunosuppressants Affect Human Neural Stem Cells In Vitro but Not in an In Vivo Model of Spinal Cord Injury. 2013 Stem Cells Transl Med
In vivo response to dynamic hyaluronic acid hydrogels. 2013 Acta Biomater
Efficient Generation of Astrocytes From Human Pluripotent Stem Cells in Defined Conditions. 2013 Stem Cells
A Pan-BCL2 inhibitor renders bone-marrow-resident human leukemia stem cells sensitive to tyrosine kinase inhibition. 2013 Cell Stem Cell
Endogenous electric currents might guide rostral migration of neuroblasts. 2013 EMBO Rep
Dental mesenchymal stem cells encapsulated in an alginate hydrogel co-delivery microencapsulation system for cartilage regeneration. 2013 Acta Biomater
Targeting RNA Foci in iPSC-Derived Motor Neurons from ALS Patients with a C9ORF72 Repeat Expansion. 2013 Sci Transl Med
Nuclear factor one b regulates neural stem cell differentiation and axonal projection of corticofugal neurons. 2013 J Comp Neurol
Identification of Human Embryonic Progenitor Cell Targeting Peptides Using Phage Display. 2013 PLoS One
A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells. 2013 FASEB J
Magnetostimulation limits in magnetic particle imaging. 2013 IEEE Trans Med Imaging
PGC7, H3K9me2 and Tet3: regulators of DNA methylation in zygotes. 2013 Cell Res
hESC-derived Olig2(+) progenitors generate a subtype of astroglia with protective effects against ischaemic brain injury. 2013 Nat Commun
Mitotic spindle orientation predicts outer radial glial cell generation in human neocortex. 2013 Nat Commun
Imaging-based chemical screening reveals activity-dependent neural differentiation of pluripotent stem cells. 2013 Elife
Human trophoblast progenitors: where do they reside? 2013 Semin Reprod Med
Presence of native limbal stromal cells increases the expansion efficiency of limbal stem/progenitor cells in culture. 2013 Exp Eye Res
A fully defined and scalable 3D culture system for human pluripotent stem cell expansion and differentiation. 2013 Proc Natl Acad Sci U S A
Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/beta-catenin/CBP pathway. 2013 Int J Cancer
Engineering of three-dimensional microenvironments to promote contractile behavior in primary intestinal organoids. 2013 Integr Biol (Camb)
Usp16 contributes to somatic stem-cell defects in Down's syndrome. 2013 Nature
hESC-secreted proteins can be enriched for multiple regenerative therapies by heparin-binding. 2013 Aging (Albany NY)
Neuroglobin expression in neurogenesis. 2013 Neurosci Lett
Combinatorial RNA-based gene therapy for the treatment of HIV/AIDS. 2013 Expert Opin Biol Ther
Human genetic variation within neural crest enhancers: molecular and phenotypic implications. 2013 Philos Trans R Soc Lond B Biol Sci
A far downstream enhancer for murine Bcl11b controls its T-cell specific expression. 2013 Blood
Histone Acetylation Regulates Intracellular pH. 2013 Mol Cell
Gingivae contain neural-crest- and mesoderm-derived mesenchymal stem cells. 2013 J Dent Res
Genome organization and long-range regulation of gene expression by enhancers. 2013 Curr Opin Cell Biol

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