Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans. 2012 Proc Natl Acad Sci U S A
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. 2012 PLoS One
Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal. 2012 Cell Stem Cell
Stage-Specific Cardiomyocyte Differentiation Method for H7 and H9 Human Embryonic Stem Cells. 2012 Stem Cell Rev
Efficient reversal of phiC31 integrase recombination in mammalian cells. 2012 Biotechnol J
A roundabout way to cancer. 2012 Adv Cancer Res
Transcriptional Analysis of Pluripotency Reveals the Hippo Pathway as a Barrier to Reprogramming. 2012 Hum Mol Genet
Molecular roadblocks for cellular reprogramming. 2012 Mol Cell
Effect of substrate stiffness on early mouse embryo development. 2012 PLoS One
Widespread dynamic DNA methylation in response to biotic stress. 2012 Proc Natl Acad Sci U S A
Small molecules, big roles - the chemical manipulation of stem cell fate and somatic cell reprogramming. 2012 J Cell Sci
The RB family is required for the self-renewal and survival of human embryonic stem cells. 2012 Nat Commun
TCF/LEFs and Wnt Signaling in the Nucleus. 2012 Cold Spring Harb Perspect Biol
Mineralized Synthetic Matrices as an Instructive Microenvironment for Osteogenic Differentiation of Human Mesenchymal Stem Cells. 2012 Macromol Biosci
Human neural stem cell tropism to metastatic breast cancer. 2012 Stem Cells
Characterization and therapeutic potential of induced pluripotent stem cell-derived cardiovascular progenitor cells. 2012 PLoS One
ADAR1 promotes malignant progenitor reprogramming in chronic myeloid leukemia. 2012 Proc Natl Acad Sci U S A
Alcam Regulates Long-term Hematopoietic Stem Cell Engraftment and Self-Renewal. 2012 Stem Cells
Bmps and id2a act upstream of Twist1 to restrict ectomesenchyme potential of the cranial neural crest. 2012 PLoS Genet
Stem cells and modeling of autism spectrum disorders. 2012 Exp Neurol
Drosophila models of epithelial stem cells and their niches. 2012 Wiley Interdiscip Rev Dev Biol
Identification of miRNA Signatures during the Differentiation of hESCs into Retinal Pigment Epithelial Cells. 2012 PLoS One
Analysis of the endocardial-to-mesenchymal transformation of heart valve development by collagen gel culture assay. 2012 Methods Mol Biol
Pleiotrophin Regulates the Retention and Self-Renewal of Hematopoietic Stem Cells in the Bone Marrow Vascular Niche. 2012 Cell Rep
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. 2012 Am J Physiol Lung Cell Mol Physiol
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. 2012 Nature
Transcriptional regulation of TRKC by SOX2 in human embryonic stem cells. 2012 Stem Cell Res
Essential role for Notch signaling in restricting developmental plasticity. 2012 Genes Dev
Cardiac tissue development for delivery of embryonic stem cell-derived endothelial and cardiac cells in natural matrices. 2012 J Biomed Mater Res B Appl Biomater
Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. 2012 Nat Biotechnol
Rapid Thymic Reconstitution Following Bone Marrow Transplantation in Neonatal Mice is VEGF-Dependent. 2012 Biol Blood Marrow Transplant
Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. 2012 Blood
Key anticipated regulatory issues for clinical use of human induced pluripotent stem cells. 2012 Regen Med
Striatal atrophy and dendritic alterations in a knock-in mouse model of Huntington's disease. 2012 Brain Res Bull
Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage. 2012 Nat Commun
Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway. 2012 PLoS One
Potent low toxicity inhibition of human melanogenesis by novel indole-containing octapeptides. 2012 Biochim Biophys Acta
Trophoblasts Regulate the Placental Hematopoietic Niche through PDGF-B Signaling. 2012 Dev Cell
Selective elimination of leukemia stem cells: Hitting a moving target. 2012 Cancer Lett
The gene expression profiles of induced pluripotent stem cells from individuals with childhood cerebral adrenoleukodystrophy are consistent with proposed mechanisms of pathogenesis. 2012 Stem Cell Res Ther
Ubiquitin-dependent regulation of COPII coat size and function. 2012 Nature
Epigenetic regulation of stem cells differentiating along the neural lineage. 2012 Curr Opin Neurobiol
Highly parallel genome-wide expression analysis of single mammalian cells. 2012 PLoS One
Topological domains in mammalian genomes identified by analysis of chromatin interactions. 2012 Nature
Analysis of the patterning of cardiac outflow tract and great arteries with angiography and vascular casting. 2012 Methods Mol Biol
Neural progenitor cells regulate microglia functions and activity. 2012 Nat Neurosci
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. 2012 Development
Projection x-space magnetic particle imaging. 2012 IEEE Trans Med Imaging
Additive Effects of Sonic Hedgehog and Nell-1 Signaling in Osteogenic versus Adipogenic Differentiation of Human Adipose-Derived Stromal Cells. 2012 Stem Cells Dev
A self-limiting switch based on translational control regulates the transition from proliferation to differentiation in an adult stem cell lineage. 2012 Cell Stem Cell


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