Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Cancer stem cells generated by alcohol, diabetes, and hepatitis C virus. 2012 J Gastroenterol Hepatol
Mitochondrial DNA variant associated with Leber hereditary optic neuropathy and high-altitude Tibetans. 2012 Proc Natl Acad Sci U S A
Transcriptional Analysis of Pluripotency Reveals the Hippo Pathway as a Barrier to Reprogramming. 2012 Hum Mol Genet
Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage. 2012 Stem Cells Int
Human neural stem cell tropism to metastatic breast cancer. 2012 Stem Cells
Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. 2012 J Cell Sci
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. 2012 Nature
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. 2012 Stem Cells Dev
Release Factor One Is Nonessential in Escherichia coli. 2012 ACS Chem Biol
Rapid Thymic Reconstitution Following Bone Marrow Transplantation in Neonatal Mice is VEGF-Dependent. 2012 Biol Blood Marrow Transplant
The retinoblastoma tumor suppressor and stem cell biology. 2012 Genes Dev
Role of mismatch repair enzymes in GAA-TTC triplet-repeat expansion in Friedreich's ataxia induced pluripotent stem cells (iPSCs). 2012 J Biol Chem
Numb Expression and Asymmetric Versus Symmetric Cell Division in Distal Embryonic Lung Epithelium. 2012 J Histochem Cytochem
Topological domains in mammalian genomes identified by analysis of chromatin interactions. 2012 Nature
Projection x-space magnetic particle imaging. 2012 IEEE Trans Med Imaging
Mineralized Synthetic Matrices as an Instructive Microenvironment for Osteogenic Differentiation of Human Mesenchymal Stem Cells. 2012 Macromol Biosci
Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes. 2012 Cell Stem Cell
High-throughput screening in primary neurons. 2012 Methods Enzymol
Adoptive transfer of induced-treg cells effectively attenuates murine airway allergic inflammation. 2012 PLoS One
A roundabout way to cancer. 2012 Adv Cancer Res
Wnt Inhibition Correlates with Human Embryonic Stem Cell Cardiomyogenesis: A Structure-Activity Relationship Study Based on Inhibitors for the Wnt Response. 2012 J Med Chem
Potent low toxicity inhibition of human melanogenesis by novel indole-containing octapeptides. 2012 Biochim Biophys Acta
Identification of a Ckit+ Colonic Crypt Base Secretory Cell that Supports Lgr5+ Stem Cells in Mice. 2012 Gastroenterology
mtDNA lineage analysis of mouse L-cell lines reveals the accumulation of multiple mtDNA mutants and intermolecular recombination. 2012 Genes Dev
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. 2012 Am J Physiol Lung Cell Mol Physiol
Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. 2012 Nat Biotechnol
Active chromatin and noncoding RNAs: an intimate relationship. 2012 Curr Opin Genet Dev
Characterization of Dental Epithelial Stem Cells from the Mouse Incisor with 2D and 3D Platforms. 2012 Tissue Eng Part C Methods
aSIRTing Control over Cancer Stem Cells. 2012 Cancer Cell
Epigenetic regulation of stem cells differentiating along the neural lineage. 2012 Curr Opin Neurobiol
Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1. 2012 Hum Mol Genet
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. 2012 Development
Functional and Molecular Characterization of the Role of CTCF in Human Embryonic Stem Cell Biology. 2012 PLoS One
A Stem Cell-Based Approach to Cartilage Repair. 2012 Science
Integrins Regulate Repulsion-Mediated Dendritic Patterning of Drosophila Sensory Neurons by Restricting Dendrites in a 2D Space. 2012 Neuron
Chromatin Isolation by RNA Purification (ChIRP). 2012 J Vis Exp
In vitro culture of epicardial cells from adult zebrafish heart on a fibrin matrix. 2012 Nat Protoc
A map of the cis-regulatory sequences in the mouse genome. 2012 Nature
Induction of NANOG expression by targeting promoter sequence with small activating RNA antagonizes retinoic acid-induced differentiation. 2012 Biochem J
Polycomb-like 3 promotes polycomb repressive complex 2 binding to CpG islands and embryonic stem cell self-renewal. 2012 PLoS Genet
Molecular and biophysical basis of glutamate and trace metal modulation of voltage-gated Cav2.3 calcium channels. 2012 J Gen Physiol
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. 2012 PLoS One
Transcriptional regulation of TRKC by SOX2 in human embryonic stem cells. 2012 Stem Cell Res
Additive Effects of Sonic Hedgehog and Nell-1 Signaling in Osteogenic versus Adipogenic Differentiation of Human Adipose-Derived Stromal Cells. 2012 Stem Cells Dev
A molecular signature for purified definitive endoderm guides differentiation and isolation of endoderm from mouse and human embryonic stem cells. 2012 Stem Cells Dev
Wnt Inhibition Correlates with Human Embryonic Stem Cell Cardiomyogenesis: A Structure-Activity Relationship Study Based on Inhibitors for the Wnt Response. 2012 J Med Chem
Integrins Regulate Repulsion-Mediated Dendritic Patterning of Drosophila Sensory Neurons by Restricting Dendrites in a 2D Space. 2012 Neuron
Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells. 2011 Cell Res
Smek promotes histone deacetylation to suppress transcription of Wnt target gene brachyury in pluripotent embryonic stem cells. 2011 Cell Res
Polynucleotide kinase and aprataxin-like forkhead-associated protein (PALF) acts as both a single-stranded DNA endonuclease and a single-stranded DNA 3' exonuclease and can participate in DNA end joining in a biochemical system. 2011 J Biol Chem

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