Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
beta-globin gene transfer to human bone marrow for sickle cell disease. 2013 J Clin Invest
Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models. 2013 PLoS One
Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells. 2013 Proc Natl Acad Sci U S A
Encodes Two Isoforms with Distinct Functions in Cancers. 2013 PLoS One
Breaking down protein degradation mechanisms in cardiac muscle. 2013 Trends Mol Med
Multivalent ligands control stem cell behaviour in vitro and in vivo. 2013 Nat Nanotechnol
Understanding telomere diseases through analysis of patient-derived iPS cells. 2013 Curr Opin Genet Dev
Co-encapsulation of anti-BMP2 monoclonal antibody and mesenchymal stem cells in alginate microspheres for bone tissue engineering. 2013 Biomaterials
Introduction of Exogenous T-cell Receptors Into Human Hematopoietic Progenitors Results in Exclusion of Endogenous T-cell Receptor Expression. 2013 Mol Ther
Tracking immune cells in vivo using magnetic resonance imaging. 2013 Nat Rev Immunol
Modeling heart disease in a dish: From somatic cells to disease-relevant cardiomyocytes. 2013 Trends Cardiovasc Med
Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position. 2013 Nat Methods
Mouse TU tagging: a chemical/genetic intersectional method for purifying cell type-specific nascent RNA. 2013 Genes Dev
Frizzled 7 maintains the undifferentiated state of human limbal stem/progenitor cells. 2013 Stem Cells
Prospective isolation of human embryonic stem cell-derived cardiovascular progenitors that integrate into human fetal heart tissue. 2013 Proc Natl Acad Sci U S A
Analysis of SOX2-Expressing Cell Populations Derived from Human Pluripotent Stem Cells. 2013 Stem Cell Reports
Implications and limitations of cellular reprogramming for psychiatric drug development. 2013 Exp Mol Med
Efficient Generation of Astrocytes From Human Pluripotent Stem Cells in Defined Conditions. 2013 Stem Cells
Flk2/Flt3 promotes both myeloid and lymphoid development by expanding non-self-renewing multipotent hematopoietic progenitor cells. 2013 Exp Hematol
Distinct temporal patterns of T cell receptor signaling during positive versus negative selection in situ. 2013 Sci Signal
Transdifferentiation and remodeling of post-embryonic C. elegans cells by a single transcription factor. 2013 Development
Nipah virus envelope-pseudotyped lentiviruses efficiently target ephrinB2-positive stem cell populations in vitro and bypass the liver sink when administered in vivo. 2013 J Virol
Screening drug-induced arrhythmia [corrected] using human induced pluripotent stem cell-derived cardiomyocytes and low-impedance microelectrode arrays. 2013 Circulation
Endogenous electric currents might guide rostral migration of neuroblasts. 2013 EMBO Rep
Back to the future: how human induced pluripotent stem cells will transform regenerative medicine. 2013 Hum Mol Genet
Dental mesenchymal stem cells encapsulated in an alginate hydrogel co-delivery microencapsulation system for cartilage regeneration. 2013 Acta Biomater
Identification of Human Embryonic Progenitor Cell Targeting Peptides Using Phage Display. 2013 PLoS One
Genomic Analysis of hESC Pedigrees Identifies De Novo Mutations and Enables Determination of the Timing and Origin of Mutational Events. 2013 Cell Rep
A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells. 2013 FASEB J
An indirect approach to generating specific human cell types. 2013 Nat Methods
Contextual effect of repression of bone morphogenetic protein activity in prostate cancer. 2013 Endocr Relat Cancer
Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells. 2013 Proc Natl Acad Sci U S A
A dynamic population of stromal cells contributes to the follicle stem cell niche in the Drosophila ovary. 2013 Development
Factors affecting the structure and maturation of human tissue engineered skeletal muscle. 2013 Biomaterials
A Three-Dimensional Culture Method to Expand Limbal Stem/Progenitor Cells. 2013 Tissue Eng Part C Methods
Single-cell mass cytometry for analysis of immune system functional states. 2013 Curr Opin Immunol
Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation. 2013 Proc Natl Acad Sci U S A
Glial cell line-derived neurotrophic factor-secreting human neural progenitors show long-term survival, maturation into astrocytes, and no tumor formation following transplantation into the spinal cord of immunocompromised rats. 2013 Neuroreport
Genome-wide analysis of the bHLH gene family in planarians identifies factors required for adult neurogenesis and neuronal regeneration. 2013 Development
Quantification of biomass and cell motion in human pluripotent stem cell colonies. 2013 Biophys J
Combinatorial RNA-based gene therapy for the treatment of HIV/AIDS. 2013 Expert Opin Biol Ther
Engineering of three-dimensional microenvironments to promote contractile behavior in primary intestinal organoids. 2013 Integr Biol (Camb)
Rapid single-step induction of functional neurons from human pluripotent stem cells. 2013 Neuron
Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression. 2013 J Exp Med
Histone Acetylation Regulates Intracellular pH. 2013 Mol Cell
A population of Nestin-expressing progenitors in the cerebellum exhibits increased tumorigenicity. 2013 Nat Neurosci
Characterization of Growth, Glomerular Number, and Tubular Proteins in the Developing Rhesus Monkey Kidney. 2013 Anat Rec (Hoboken)
Genome organization and long-range regulation of gene expression by enhancers. 2013 Curr Opin Cell Biol
Chemical approaches to stem cell biology and therapeutics. 2013 Cell Stem Cell
Tumor suppressors: enhancers or suppressors of regeneration? 2013 Development

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