Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Uncovering the role of genomic "dark matter" in human disease. 2012 J Clin Invest
Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells. 2012 Nature
Exogenous leukemia inhibitory factor stimulates oligodendrocyte progenitor cell proliferation and enhances hippocampal remyelination. 2012 J Neurosci
Foxp-mediated suppression of N-cadherin regulates neuroepithelial character and progenitor maintenance in the CNS. 2012 Neuron
Reexamining hydroxamate inhibitors of botulinum neurotoxin serotype A: Extending towards the beta-exosite. 2012 Bioorg Med Chem Lett
Direct conversion of mouse fibroblasts to self-renewing, tripotent neural precursor cells. 2012 Proc Natl Acad Sci U S A
Injectable skeletal muscle matrix hydrogel promotes neovascularization and muscle cell infiltration in a hindlimb ischemia model. 2012 Eur Cell Mater
A microRNA-21 surge facilitates rapid cyclin D1 translation and cell cycle progression in mouse liver regeneration. 2012 J Clin Invest
Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. 2012 J Cell Sci
Three differentiation states risk-stratify bladder cancer into distinct subtypes. 2012 Proc Natl Acad Sci U S A
Small molecules greatly improve conversion of human-induced pluripotent stem cells to the neuronal lineage. 2012 Stem Cells Int
Correcting human mitochondrial mutations with targeted RNA import. 2012 Proc Natl Acad Sci U S A
Role of mismatch repair enzymes in GAA-TTC triplet-repeat expansion in Friedreich's ataxia induced pluripotent stem cells (iPSCs). 2012 J Biol Chem
MicroRNA profiling predicts a variance in the proliferative potential of cardiac progenitor cells derived from neonatal and adult murine hearts. 2012 J Mol Cell Cardiol
Numb Expression and Asymmetric Versus Symmetric Cell Division in Distal Embryonic Lung Epithelium. 2012 J Histochem Cytochem
miR-125b Promotes Early Germ Layer Specification through Lin28/let-7d and Preferential Differentiation of Mesoderm in Human Embryonic Stem Cells. 2012 PLoS One
Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells. 2012 PLoS One
Release Factor One Is Nonessential in Escherichia coli. 2012 ACS Chem Biol
A single cell bioengineering approach to elucidate mechanisms of adult stem cell self-renewal. 2012 Integr Biol (Camb)
The retinoblastoma tumor suppressor and stem cell biology. 2012 Genes Dev
Induced Pluripotent Stem Cells from Patients with Huntington's Disease Show CAG-Repeat-Expansion-Associated Phenotypes. 2012 Cell Stem Cell
Modeling psychiatric disorders at the cellular and network levels. 2012 Mol Psychiatry
Adoptive transfer of induced-treg cells effectively attenuates murine airway allergic inflammation. 2012 PLoS One
Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. 2012 PLoS One
Advances in treatment and management: immunologic and cell-based regenerative therapies. 2012 Invest Ophthalmol Vis Sci
Dynamic expression of the Robo ligand Slit2 in bone marrow cell populations. 2012 Cell Cycle
Library-free methylation sequencing with bisulfite padlock probes. 2012 Nat Methods
Mineralized Synthetic Matrices as an Instructive Microenvironment for Osteogenic Differentiation of Human Mesenchymal Stem Cells. 2012 Macromol Biosci
Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. 2012 Am J Physiol Lung Cell Mol Physiol
A roundabout way to cancer. 2012 Adv Cancer Res
Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives. 2012 Cell Stem Cell
Potent low toxicity inhibition of human melanogenesis by novel indole-containing octapeptides. 2012 Biochim Biophys Acta
Epigenetic regulation of stem cells differentiating along the neural lineage. 2012 Curr Opin Neurobiol
Cochlea Radiation Dose Correlates with Hearing Loss Following Stereotactic Radiosurgery of Vestibular Schwannoma. 2012 World Neurosurg
A Sox9/Fgf feed-forward loop maintains pancreatic organ identity. 2012 Development
Cdk2ap2 is a Novel Regulator for Self-Renewal of Murine Embryonic Stem Cells. 2012 Stem Cells Dev
Isolation of primitive endoderm, mesoderm, vascular endothelial and trophoblast progenitors from human pluripotent stem cells. 2012 Nat Biotechnol
Measuring energy metabolism in cultured cells, including human pluripotent stem cells and differentiated cells. 2012 Nat Protoc
Context-Dependent Enhancement of Induced Pluripotent Stem Cell Reprogramming by Silencing Puma. 2012 Stem Cells
Characterization of Dental Epithelial Stem Cells from the Mouse Incisor with 2D and 3D Platforms. 2012 Tissue Eng Part C Methods
Arrayed cellular microenvironments for identifying culture and differentiation conditions for stem, primary and rare cell populations. 2012 Nat Protoc
Frequency discretization in dielectrophoretic assisted cell sorting arrays to isolate neural cells. 2012 Lab Chip
Functional and Molecular Characterization of the Role of CTCF in Human Embryonic Stem Cell Biology. 2012 PLoS One
Identification of functional progenitor cells in the pulmonary vasculature. 2012 Pulm Circ
Tissue-engineering of the gastrointestinal tract. 2012 Curr Opin Pediatr
Injection of Amniotic Fluid Stem Cells Delays Progression of Renal Fibrosis. 2012 J Am Soc Nephrol
A map of the cis-regulatory sequences in the mouse genome. 2012 Nature
A ZFN/piggyBac step closer to autologous liver cell therapy. 2012 Hepatology
Pluripotency factor-mediated expression of the leptin receptor (OB-R) links obesity to oncogenesis through tumor-initiating stem cells. 2012 Proc Natl Acad Sci U S A
Additive Effects of Sonic Hedgehog and Nell-1 Signaling in Osteogenic versus Adipogenic Differentiation of Human Adipose-Derived Stromal Cells. 2012 Stem Cells Dev

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