Publications by CIRM grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

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Year Journal
Preclinical studies for a phase 1 clinical trial of autologous hematopoietic stem cell gene therapy for sickle cell disease. 2017 Cytotherapy
In Vivo Human Somitogenesis Guides Somite Development from hPSCs. 2017 Cell Rep
Engineered HA hydrogel for stem cell transplantation in the brain: Biocompatibility data using a design of experiment approach. 2017 Data Brief
A small molecule screen to identify regulators of let-7 targets. 2017 Sci Rep
Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism. 2017 Nat Cell Biol
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. 2017 Elife
Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. 2017 Dev Cell
Multiplexed genetic engineering of human hematopoietic stem and progenitor cells using CRISPR/Cas9 and AAV6. 2017 Elife
Resolving stem and progenitor cells in the adult mouse incisor through gene co-expression analysis. 2017 Elife
Lessons from Interspecies Mammalian Chimeras. 2017 Annu Rev Cell Dev Biol
CRISPR/Cas9 microinjection in oocytes disables pancreas development in sheep. 2017 Sci Rep
In Vivo Generation of Engraftable Murine Hematopoietic Stem Cells by Gfi1b, c-Fos, and Gata2 Overexpression within Teratoma. 2017 Stem Cell Reports
Mechanoresponsive stem cells to target cancer metastases through biophysical cues. 2017 Sci Transl Med
The effect of Nipped-B-like (Nipbl) haploinsufficiency on genome-wide cohesin binding and target gene expression: modeling Cornelia de Lange syndrome. 2017 Clin Epigenetics
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS). 2017 Proc Natl Acad Sci U S A
Cell-mediated enzyme prodrug cancer therapies. 2017 Adv Drug Deliv Rev
BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities. 2017 Elife
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model. 2017 Immunity
Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection. 2017 Cell Rep
In vitro patterning of pluripotent stem cell-derived intestine recapitulates in vivo human development. 2017 Development
SERS-enhanced piezoplasmonic graphene composite for biological and structural strain mapping. 2017 Nanoscale
Nanofibre optic force transducers with sub-piconewton resolution via near-field plasmon-dielectric interactions. 2017 Nat Photonics
3D-printed biomaterials with regional auxetic properties. 2017 J Mech Behav Biomed Mater
Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data. 2017 Nat Commun
Nkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal Heart. 2017 Sci Rep
Molecular and functional resemblance of differentiated cells derived from isogenic human iPSCs and SCNT-derived ESCs. 2017 Proc Natl Acad Sci U S A
Genome-Wide Temporal Profiling of Transcriptome and Open Chromatin of Early Cardiomyocyte Differentiation Derived From hiPSCs and hESCs. 2017 Circ Res
Controlling the Release of Small, Bioactive Proteins via Dual Mechanisms with Therapeutic Potential. 2017 Adv Healthc Mater
Tuning and Predicting Mesh Size and Protein Release from Step Growth Hydrogels. 2017 Biomacromolecules
Metabolic shift in density-dependent stem cell differentiation. 2017 Cell Commun Signal
Leaf-inspired microcontact printing vascular patterns. 2017 Biofabrication
Development of Mural Cells: From In Vivo Understanding to In Vitro Recapitulation. 2017 Stem Cells Dev
Lineage- and developmental stage-specific mechanomodulation of induced pluripotent stem cell differentiation. 2017 Stem Cell Res Ther
A Hyper-Crosslinked Carbohydrate Polymer Scaffold Facilitates Lineage Commitment and Maintains a Reserve Pool of Proliferating Cardiovascular Progenitors. 2017 Transplant Direct
SLC7A11 Overexpression in Glioblastoma Is Associated with Increased Cancer Stem Cell-Like Properties. 2017 Stem Cells Dev
Anodization of magnesium for biomedical applications - Processing, characterization, degradation and cytocompatibility. 2017 Acta Biomater
Potential clinical applications of placental stem cells for use in fetal therapy of birth defects. 2017 Placenta
A post-translational modification switch controls coactivator function of histone methyltransferases G9a and GLP. 2017 EMBO Rep
Frequency of mononuclear diploid cardiomyocytes underlies natural variation in heart regeneration. 2017 Nat Genet
WNT-activated bone grafts repair osteonecrotic lesions in aged animals. 2017 Sci Rep
Mammalian Transcription Factor Networks: Recent Advances in Interrogating Biological Complexity. 2017 Cell Syst
An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors. 2017 Stem Cell Reports
Interspecies organogenesis generates autologous functional islets. 2017 Nature
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis. 2017 Proc Natl Acad Sci U S A
An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. 2017 Front Physiol
Three-Dimensional Bioprinting and Its Potential in the Field of Articular Cartilage Regeneration. 2017 Cartilage
Human fetal liver cultures support multiple cell lineages that can engraft immunodeficient mice. 2017 Open Biol
Identification and characterization of a rich population of CD34(+) mesenchymal stem/stromal cells in human parotid, sublingual and submandibular glands. 2017 Sci Rep
Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. 2017 Cell Rep
Engineered hydrogels increase the post-transplantation survival of encapsulated hESC-derived midbrain dopaminergic neurons. 2017 Biomaterials

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