Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
High-level correction of the sickle mutation is amplified in vivo during erythroid differentiation. 2022 iScience
High-throughput characterization of the role of non-B DNA motifs on promoter function. 2022 Cell Genom
HUMAN CELLULAR MODELS FOR RETINAL DISEASE: From Induced Pluripotent Stem Cells to Organoids. 2022 Retina
IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis. 2022 Nat Commun
IL7Ralpha, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells. 2022 Development
Impact of Gestational Age on Neuroprotective Function of Placenta-Derived Mesenchymal Stromal Cells. 2022 J Surg Res
Impact of pre-existing chronic viral infection and reactivation on the development of long COVID. 2022 J Clin Invest
Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion. 2022 EBioMedicine
Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium. 2022 Nat Commun
Interorgan crosstalk in pancreatic islet function and pathology. 2022 FEBS Lett
Isogenic human SNCA gene dosage induced pluripotent stem cells to model Parkinson’s disease. 2022 Stem Cell Res
Lifelong single-cell profiling of cranial neural crest diversification in zebrafish. 2022 Nat Commun
lincRNA-Cox2 Functions to Regulate Inflammation in Alveolar Macrophages during Acute Lung Injury. 2022 J Immunol
LncRNA Biomarkers of Inflammation and Cancer. 2022 Adv Exp Med Biol
Lymphangiocrine signals are required for proper intestinal repair after cytotoxic injury. 2022 Cell Stem Cell
Microcarrier-Based Culture of Human Pluripotent Stem-Cell-Derived Retinal Pigmented Epithelium. 2022 Bioengineering (Basel)
Modeling Effects of Immunosuppressive Drugs on Human Hearts Using Induced Pluripotent Stem Cell-Derived Cardiac Organoids and Single-Cell RNA Sequencing. 2022 Circulation
Modular automated microfluidic cell culture platform reduces glycolytic stress in cerebral cortex organoids. 2022 Sci Rep
Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin. 2022 Cancer Cell
Mutant KRAS regulates transposable element RNA and innate immunity via KRAB zinc-finger genes. 2022 Cell Rep
Not all cortical organoids are created equal. 2022 Nat Cell Biol
Novel Humanized Peripheral Blood Mononuclear Cell Mouse Model with Delayed Onset of Graft-versus-Host Disease for Preclinical HIV Research. 2022 J Virol
Off-the-shelf, steroid-resistant, IL13Ralpha2-specific CAR T cells for treatment of glioblastoma. 2022 Neuro Oncol
Online seminars as an information source for direct-to-consumer stem cell therapy. 2022 Regen Med
Organotypic cultures as aging associated disease models. 2022 Aging (Albany NY)
Partial Tendon Injury at the Tendon-to-Bone Enthesis Activates Skeletal Stem Cells. 2022 Stem Cells Transl Med
Phase 1/1b Study of T-allo10 Infusion after HLA-Partially Matched αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Preliminary Results. 2022 Transplantation and Cellular Therapy
Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development. 2022 J Gen Physiol
Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion. 2022 Circ Res
Plasticity of muscle stem cells in homeostasis and aging. 2022 Curr Opin Genet Dev
Pre-clinical data supporting immunotherapy for HIV using CMV-HIV-specific CAR T cells with CMV vaccine. 2022 Mol Ther Methods Clin Dev
Preclinical Development and Evaluation of Allogeneic CAR T Cells Targeting CD70 for the Treatment of Renal Cell Carcinoma. 2022 Cancer Res
Primary and metastatic tumors exhibit systems-level differences in dependence on mitochondrial respiratory function. 2022 PLoS Biol
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during aging. 2022 Nat Commun
Procurement of Deceased Donor Parathyroid Glands With the Aid of Near-infrared Autofluorescence Imaging. 2022 Transplant Direct
Proteomic analysis of the actin cortex in interphase and mitosis. 2022 J Cell Sci
Recent advancements and future requirements in vascularization of cortical organoids. 2022 Front Bioeng Biotechnol
Sexually dimorphic estrogen sensing in skeletal stem cells controls skeletal regeneration. 2022 Nat Commun
Sidestream Smoke Extracts from Harm-Reduction and Conventional Camel Cigarettes Inhibit Osteogenic Differentiation via Oxidative Stress and Differential Activation of intrinsic Apoptotic Pathways. 2022 Antioxidants (Basel)
Spatial organization of heterogeneous immunotherapy target antigen expression in high-grade glioma. 2022 Neoplasia
Spatial transcriptomics using combinatorial fluorescence spectral and lifetime encoding, imaging and analysis. 2022 Nat Commun
Spina Bifida: A Review of the Genetics, Pathophysiology and Emerging Cellular Therapies. 2022 J Dev Biol
Stability and Function of Extracellular Vesicles Derived from Immortalized Human Corneal Stromal Stem Cells: A Proof of Concept Study. 2022 AAPS J
Stem Cell-Derived Islets for Type 2 Diabetes. 2022 Int J Mol Sci
Stromal AR inhibits prostate tumor progression by restraining secretory luminal epithelial cells. 2022 Cell Rep
SZN-413, a FZD4 Agonist, as a Potential Novel Therapeutic for the Treatment of Diabetic Retinopathy. 2022 Transl Vis Sci Technol
Targeting Epigenetic Modifiers of Tumor Plasticity and Cancer Stem Cell Behavior. 2022 Cells
Targeting Immunosuppressive Tumor-Associated Macrophages Using Innate T Cells for Enhanced Antitumor Reactivity. 2022 Cancers (Basel)
Telemedicine Experience of General Surgery Trainees: Impact on Patient Care and Education. 2022 Am Surg
TGFbeta superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids. 2022 Stem Cell Reports