Publications by Grantees

CIRM funding supported the following publications. Click on the publication title for a brief summary of the research and for more information:

Title Year Journal
Temporally distinct 3D multi-omic dynamics in the developing human brain. 2024 Nature
The Benefits of Stem Cell Biology and Tissue Engineering in Low-Earth Orbit. 2024 Stem Cells Dev
The Importance, Challenges, and Possible Solutions for Sharing Proteomics Data While Safeguarding Individuals’ Privacy. 2024 Mol Cell Proteomics
The JAK inhibitor, Tofacitinib, Corrects the Overexpression of CEACAM6 and Limits Susceptibility to AIEC Caused by Reduced Activity of the IBD Associated Gene, PTPN2. 2024 medRxiv
The rise of epitranscriptomics: recent developments and future directions. 2024 Trends Pharmacol Sci
The spatially resolved transcriptome signatures of glomeruli in chronic kidney disease. 2024 JCI Insight
The tardigrade-derived mitochondrial abundant heat soluble protein improves adipose-derived stem cell survival against representative stressors. 2024 Sci Rep
Therapeutic potential of human microglia transplantation in a chimeric model of CSF1R-related leukoencephalopathy. 2024 Neuron
Tissue-Engineered Three-Dimensional Platforms for Disease Modeling and Therapeutic Development. 2024 Tissue Eng Part B Rev
Ultra-high efficiency T cell reprogramming at multiple loci with SEED-Selection. 2024 bioRxiv
Uncovering Minimal Pathways in Melanoma Initiation. 2024 bioRxiv
Updated single cell reference atlas for the starlet anemone Nematostella vectensis. 2024 Front Zool
Visualizing PIEZO1 Localization and Activity in hiPSC-Derived Single Cells and Organoids with HaloTag Technology. 2024 bioRxiv
Vulvar dermatoses and depression: A systematic review of vulvar lichen sclerosus, lichen planus, and lichen simplex chronicus. 2024 JAAD Int
Widespread Gene Editing in the Brain via In Utero Delivery of mRNA Using Acid-Degradable Lipid Nanoparticles. 2024 ACS Nano
[Cystinosis: From the gene identification to the first gene therapy clinical trial]. 2023 Med Sci (Paris)
A bio-instructive parylene-based conformal coating suppresses thrombosis and intimal hyperplasia of implantable vascular devices. 2023 Bioact Mater
A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. 2023 Bioact Mater
A covalent inhibitor of the YAP-TEAD transcriptional complex identified by high-throughput screening. 2023 RSC Chem Biol
A Roadmap for a Consensus Human Skin Cell Atlas and Single-Cell Data Standardization. 2023 J Invest Dermatol
A scalable, GMP-compatible, autologous organotypic cell therapy for Dystrophic Epidermolysis Bullosa. 2023 bioRxiv
A spatially resolved single-cell genomic atlas of the adult human breast. 2023 Nature
AAV-SPL 2.0, a Modified Adeno-Associated Virus Gene Therapy Agent for the Treatment of Sphingosine Phosphate Lyase Insufficiency Syndrome. 2023 Int J Mol Sci
Abrupt perturbation and delayed recovery of the vaginal ecosystem following childbirth. 2023 Nat Commun
Advancing cell-based cancer immunotherapy through stem cell engineering. 2023 Cell Stem Cell
Airway ciliated cells in adult lung homeostasis and COPD. 2023 Eur Respir Rev
Allele-specific expression reveals genetic drivers of tissue regeneration in mice. 2023 Cell Stem Cell
An altered extracellular matrix-integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells. 2023 Hum Mol Genet
An Inexpensive 3D Printed Mouse Model of Successful, Complication-free Long Bone Distraction Osteogenesis. 2023 Plast Reconstr Surg Glob Open
An iPSC-derived astrocyte model of fragile X syndrome exhibits dysregulated cholesterol homeostasis. 2023 Commun Biol
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting. 2023 Nat Commun
Antiretrovirals to CCR5 CRISPR/Cas9 gene editing – A paradigm shift chasing an HIV cure. 2023 Clin Immunol
Assaying Chemical Long-Term Potentiation in Human iPSC-Derived Neuronal Networks. 2023 Methods Mol Biol
Attenuating Chronic Fibrosis: Decreasing Foreign Body Response with Acellular Dermal Matrix. 2023 Tissue Eng Part B Rev
Automated 384-well SYBR Green Expression Array for Optimization of Human Induced Pluripotent Stem Cell Differentiation. 2023 Bio Protoc
Biodegradable nanoparticles targeting circulating immune cells reduce central and peripheral sensitization to alleviate neuropathic pain following spinal cord injury. 2023 Pain
Bridging the gap with bacterial art. 2023 FEMS Microbiol Lett
Broadly neutralizing antibodies targeting HIV: Progress and challenges. 2023 Clin Immunol
CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma. 2023 Front Oncol
Cellular Therapy for Children with Central Nervous System Tumors: Mining and Mapping the Correlative Data. 2023 Curr Oncol Rep
Chemically Defined Production of Tri-Lineage Human iPSC-Derived Cardiac Spheroids. 2023 Curr Protoc
Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue. 2023 Arterioscler Thromb Vasc Biol
Comparative analysis between single-cell RNA-seq and single-molecule RNA FISH indicates that the pyrimidine nucleobase idoxuridine (IdU) globally amplifies transcriptional noise. 2023 bioRxiv
Complex urban atmosphere alters alveolar stem cells niche properties and drives lung fibrosis. 2023 Am J Physiol Lung Cell Mol Physiol
Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation. 2023 Biomaterials
Context matters: hPSC-derived microglia thrive in a humanized brain environment in vivo. 2023 Cell Stem Cell
Coordination between ECM and cell-cell adhesion regulates the development of islet aggregation, architecture, and functional maturation. 2023 Elife
Craniofacial developmental biology in the single-cell era. 2023 Development
CryoET reveals organelle phenotypes in huntington disease patient iPSC-derived and mouse primary neurons. 2023 Nat Commun
Dermomyotome-derived endothelial cells migrate to the dorsal aorta to support hematopoietic stem cell emergence. 2023 Elife