Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
A reference human induced pluripotent stem cell line for large-scale collaborative studies. 2022 Cell Stem Cell
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. 2022 Cell Stem Cell
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice. 2022 Cell Rep
Adapting Physiology in Functional Human Islet Organogenesis. 2022 Front Cell Dev Biol
Adult Expression of Tbr2 Is Required for the Maintenance but Not Survival of Intrinsically Photosensitive Retinal Ganglion Cells. 2022 Front Cell Neurosci
Advancing preclinical models of psychiatric disorders with human brain organoid cultures. 2022 Mol Psychiatry
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. 2022 Nat Neurosci
An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy. 2022 Cells
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. 2022 Nat Med
Antibody screening data of human midgestation liver cells with a focus on hematopoietic, liver sinusoidal endothelial, and hepatoblast cell-populations. 2022 BMC Res Notes
Autophagy inducer rapamycin treatment reduces IFN-I-mediated Inflammation and improves anti-HIV-1 T cell response in vivo. 2022 JCI Insight
Biallelic pathogenic variants in COX11 are associated with an infantile-onset mitochondrial encephalopathy. 2022 Hum Mutat
Biomarkers of in vivo limbal stem cell function. 2022 Ocul Surf
Brain organoids, consciousness, ethics and moral status. 2022 Semin Cell Dev Biol
c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. 2022 iScience
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. 2022 Cell
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. 2022 Nat Commun
Cell Morphology as an In Vivo Parameter for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Cloud-controlled microscopy enables remote project-based biology education in underserved Latinx communities. 2022 Heliyon
Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal alpha-Adrenergic Signaling and a Transient Loss of Vascular Tone. 2022 Front Cardiovasc Med
Comment on: Long-Term Outcome After Superficial Keratectomy of the Abnormal Epithelium for Partial Limbal Stem Cell Deficiency. 2022 Am J Ophthalmol
COVID-19 vaccination elicits an evolving, cross-reactive antibody response to epitopes conserved with endemic coronavirus spike proteins. 2022 Cell Rep
Cross-species comparisons reveal resistance of human skeletal stem cells to inhibition by non-steroidal anti-inflammatory drugs. 2022 Front Endocrinol (Lausanne)
Cytokeratin 13 Is a New Biomarker for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Decellularized Adipose Matrices Can Alleviate Radiation-Induced Skin Fibrosis. 2022 Adv Wound Care (New Rochelle)
Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention. 2022 Stem Cell Res Ther
Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting. 2022 Sci Transl Med
Dose-dependent thresholds of dexamethasone destabilize CAR T-cell treatment efficacy. 2022 PLoS Comput Biol
DYNC1LI2 regulates localization of the chaperone-mediated autophagy receptor LAMP2A and improves cellular homeostasis in cystinosis. 2022 Autophagy
Early investigations into improving bowel and bladder function in fetal ovine myelomeningocele repair. 2022 J Pediatr Surg
EED is required for mouse primordial germ cell differentiation in the embryonic gonad. 2022 Dev Cell
Effects of Multi-stage Procurement on the Viability and Function of Human Donor Parathyroid Glands. 2022 J Surg Res
Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration. 2022 Cell Stem Cell
Engineered extracellular vesicles with high collagen-binding affinity present superior in situ retention and therapeutic efficacy in tissue repair. 2022 Theranostics
Engineering Extracellular Microenvironment for Tissue Regeneration. 2022 Bioengineering (Basel)
Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain. 2022 Cell
Erratum. 2022 Muscle Nerve
Establishment of Chimerism and Organ Transplant Tolerance in Laboratory Animals: Safety and Efficacy of Adaptation to Humans. 2022 Front Immunol
Estrogen-Related Receptor gamma Maintains Pancreatic Acinar Cell Function and Identity by Regulating Cellular Metabolism. 2022 Gastroenterology
Exposure to Cigarette Smoke Impedes Human Osteoblast Differentiation Independently of Nicotine. 2022 Nicotine Tob Res
Gene Expression Analysis in Stem Cell-derived Cortical Neuronal Cultures Using Multi-well SYBR Green Quantitative PCR Arrays. 2022 Bio Protoc
High-level correction of the sickle mutation is amplified in vivo during erythroid differentiation. 2022 iScience
High-throughput characterization of the role of non-B DNA motifs on promoter function. 2022 Cell Genom
HUMAN CELLULAR MODELS FOR RETINAL DISEASE: From Induced Pluripotent Stem Cells to Organoids. 2022 Retina
IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis. 2022 Nat Commun
IL7Ralpha, but not Flk2, is required for hematopoietic stem cell reconstitution of tissue-resident lymphoid cells. 2022 Development
Impact of Gestational Age on Neuroprotective Function of Placenta-Derived Mesenchymal Stromal Cells. 2022 J Surg Res
Impact of pre-existing chronic viral infection and reactivation on the development of long COVID. 2022 J Clin Invest
Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion. 2022 EBioMedicine
Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium. 2022 Nat Commun