Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Sheets of human retinal progenitor transplants improve vision in rats with severe retinal degeneration. 2018 Exp Eye Res
Short-term and long-term human or mouse organoid units generate tissue-engineered small intestine without added signalling molecules. 2018 Exp Physiol
Short-term hypoxia improves early cardiac progenitor cell function in vitro. 2018 Am J Stem Cells
Single Molecule Imaging in Live Embryos Using Lattice Light-Sheet Microscopy. 2018 Methods Mol Biol
Site-Specific Gene Editing of Human Hematopoietic Stem Cells for X-Linked Hyper-IgM Syndrome. 2018 Cell Rep
Sox2 haploinsufficiency primes regeneration and Wnt responsiveness in the mouse cochlea. 2018 J Clin Invest
SoxB1 Activity Regulates Sensory Neuron Regeneration, Maintenance, and Function in Planarians. 2018 Dev Cell
Spatiotemporal mosaic self-patterning of pluripotent stem cells using CRISPR interference. 2018 Elife
Spred1 Safeguards Hematopoietic Homeostasis against Diet-Induced Systemic Stress. 2018 Cell Stem Cell
Stage-specific Effects of Bioactive Lipids on Human iPSC Cardiac Differentiation and Cardiomyocyte Proliferation. 2018 Sci Rep
Stem cell characteristics and the therapeutic potential of amniotic epithelial cells. 2018 Am J Reprod Immunol
Stem Cell-Based Immunomodulation After Stroke: Effects on Brain Repair Processes. 2018 Stroke
Stem cells for babies and their surgeons: the future is now. 2018 J Pediatr Surg
Survival of syngeneic and allogeneic iPSC-derived neural precursors after spinal grafting in minipigs. 2018 Sci Transl Med
Targeting Tumor Hypoxia Using Nanoparticle-engineered CXCR4-overexpressing Adipose-derived Stem Cells. 2018 Theranostics
TCF7L1 suppresses primitive streak gene expression to support human embryonic stem cell pluripotency. 2018 Development
The contribution of GTF2I haploinsufficiency to Williams syndrome. 2018 Mol Cell Probes
The diagnosis of limbal stem cell deficiency. 2018 Ocul Surf
The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis. 2018 Cell
The intestinal epithelial response to damage. 2018 Sci China Life Sci
The Physical and Biochemical Properties of the Extracellular Matrix Regulate Cell Fate. 2018 Curr Top Dev Biol
The role of Hedgehog-responsive fibroblasts in facial nerve regeneration. 2018 Exp Neurol
The Use of the Humanized Mouse Model in Gene Therapy and Immunotherapy for HIV and Cancer. 2018 Front Immunol
The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism. 2018 Mol Autism
Three-Dimensional Printing of Bisphenol A-Free Polycarbonates. 2018 ACS Appl Mater Interfaces
Topological Arrangement of Cardiac Fibroblasts Regulates Cellular Plasticity. 2018 Circ Res
Transcriptionally and Functionally Distinct Mesenchymal Subpopulations Are Generated from Human Pluripotent Stem Cells. 2018 Stem Cell Reports
Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats. 2018 Invest Ophthalmol Vis Sci
Trophoblast lineage specification, differentiation and their regulation by oxygen tension. 2018 J Endocrinol
Tunable Control of Hydrogel Microstructure by Kinetic Competition between Self-Assembly and Crosslinking of Elastin-like Proteins. 2018 ACS Appl Mater Interfaces
Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate. 2018 Sci Rep
Visualization of macrophage recruitment in head and neck carcinoma model using fluorine-19 magnetic resonance imaging. 2018 Magn Reson Med
Vitamin D Switches BAF Complexes to Protect beta Cells. 2018 Cell
Wild-type Kras expands and exhausts hematopoietic stem cells. 2018 JCI Insight
X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. 2018 Stem Cell Reports
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model. 2017 Immunity
3-Dimensionally Printed, Native-Like Scaffolds for Myocardial Tissue Engineering. 2017 Circ Res
3D-printed biomaterials with regional auxetic properties. 2017 J Mech Behav Biomed Mater
A 3D Tissue-Printing Approach for Validation of Diffusion Tensor Imaging in Skeletal Muscle. 2017 Tissue Eng Part A
A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer. 2017 Nat Commun
A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3alpha and GSK3beta in Regulating Embryonic Stem Cell Fate. 2017 Dev Cell
A comparative study of chondroitin sulfate and heparan sulfate for directing three-dimensional chondrogenesis of mesenchymal stem cells. 2017 Stem Cell Res Ther
A dynamic interplay of enhancer elements regulates Klf4 expression in naive pluripotency. 2017 Genes Dev
A Hyper-Crosslinked Carbohydrate Polymer Scaffold Facilitates Lineage Commitment and Maintains a Reserve Pool of Proliferating Cardiovascular Progenitors. 2017 Transplant Direct
A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations. 2017 Elife
A novel Alzheimer’s disease drug candidate targeting inflammation and fatty acid metabolism. 2017 Alzheimers Res Ther
A Novel Hybrid Compound LLP2A-Ale Both Prevented and Rescued the Osteoporotic Phenotype in a Mouse Model of Glucocorticoid-Induced Osteoporosis. 2017 Calcif Tissue Int
A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. 2017 Biotechnol Bioeng
A post-translational modification switch controls coactivator function of histone methyltransferases G9a and GLP. 2017 EMBO Rep
A Rationally Designed, General Strategy for Membrane Orientation of Photoinduced Electron Transfer-Based Voltage-Sensitive Dyes. 2017 ACS Chem Biol