Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
The role of Hedgehog-responsive fibroblasts in facial nerve regeneration. 2018 Exp Neurol
The Use of the Humanized Mouse Model in Gene Therapy and Immunotherapy for HIV and Cancer. 2018 Front Immunol
The valproic acid rat model of autism presents with gut bacterial dysbiosis similar to that in human autism. 2018 Mol Autism
Three-Dimensional Printing of Bisphenol A-Free Polycarbonates. 2018 ACS Appl Mater Interfaces
Topological Arrangement of Cardiac Fibroblasts Regulates Cellular Plasticity. 2018 Circ Res
Transcriptionally and Functionally Distinct Mesenchymal Subpopulations Are Generated from Human Pluripotent Stem Cells. 2018 Stem Cell Reports
Transplanted hESC-Derived Retina Organoid Sheets Differentiate, Integrate, and Improve Visual Function in Retinal Degenerate Rats. 2018 Invest Ophthalmol Vis Sci
Trophoblast lineage specification, differentiation and their regulation by oxygen tension. 2018 J Endocrinol
Tunable Control of Hydrogel Microstructure by Kinetic Competition between Self-Assembly and Crosslinking of Elastin-like Proteins. 2018 ACS Appl Mater Interfaces
Using patient-derived iPSCs to develop humanized mouse models for chronic myelomonocytic leukemia and therapeutic drug identification, including liposomal clodronate. 2018 Sci Rep
Visualization of macrophage recruitment in head and neck carcinoma model using fluorine-19 magnetic resonance imaging. 2018 Magn Reson Med
Vitamin D Switches BAF Complexes to Protect beta Cells. 2018 Cell
Wild-type Kras expands and exhausts hematopoietic stem cells. 2018 JCI Insight
X Chromosome Dosage Influences DNA Methylation Dynamics during Reprogramming to Mouse iPSCs. 2018 Stem Cell Reports
25-Hydroxycholesterol Protects Host against Zika Virus Infection and Its Associated Microcephaly in a Mouse Model. 2017 Immunity
3-Dimensionally Printed, Native-Like Scaffolds for Myocardial Tissue Engineering. 2017 Circ Res
3D-printed biomaterials with regional auxetic properties. 2017 J Mech Behav Biomed Mater
A 3D Tissue-Printing Approach for Validation of Diffusion Tensor Imaging in Skeletal Muscle. 2017 Tissue Eng Part A
A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer. 2017 Nat Commun
A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3alpha and GSK3beta in Regulating Embryonic Stem Cell Fate. 2017 Dev Cell
A comparative study of chondroitin sulfate and heparan sulfate for directing three-dimensional chondrogenesis of mesenchymal stem cells. 2017 Stem Cell Res Ther
A dynamic interplay of enhancer elements regulates Klf4 expression in naive pluripotency. 2017 Genes Dev
A Hyper-Crosslinked Carbohydrate Polymer Scaffold Facilitates Lineage Commitment and Maintains a Reserve Pool of Proliferating Cardiovascular Progenitors. 2017 Transplant Direct
A minimally sufficient model for rib proximal-distal patterning based on genetic analysis and agent-based simulations. 2017 Elife
A novel Alzheimer’s disease drug candidate targeting inflammation and fatty acid metabolism. 2017 Alzheimers Res Ther
A Novel Hybrid Compound LLP2A-Ale Both Prevented and Rescued the Osteoporotic Phenotype in a Mouse Model of Glucocorticoid-Induced Osteoporosis. 2017 Calcif Tissue Int
A novel protein-engineered hepatocyte growth factor analog released via a shear-thinning injectable hydrogel enhances post-infarction ventricular function. 2017 Biotechnol Bioeng
A post-translational modification switch controls coactivator function of histone methyltransferases G9a and GLP. 2017 EMBO Rep
A Rationally Designed, General Strategy for Membrane Orientation of Photoinduced Electron Transfer-Based Voltage-Sensitive Dyes. 2017 ACS Chem Biol
A semi-interpenetrating network of polyacrylamide and recombinant basement membrane allows pluripotent cell culture in a soft, ligand-rich microenvironment. 2017 Biomaterials
A small molecule screen to identify regulators of let-7 targets. 2017 Sci Rep
Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion. 2017 Aging Cell
Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. 2017 Dev Cell
An All-Recombinant Protein-Based Culture System Specifically Identifies Hematopoietic Stem Cell Maintenance Factors. 2017 Stem Cell Reports
An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. 2017 Front Physiol
Anodization of magnesium for biomedical applications – Processing, characterization, degradation and cytocompatibility. 2017 Acta Biomater
Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. 2017 Stem Cells Int
Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS). 2017 Proc Natl Acad Sci U S A
Bcl11b and combinatorial resolution of cell fate in the T-cell gene regulatory network. 2017 Proc Natl Acad Sci U S A
Bioacoustic-enabled patterning of human iPSC-derived cardiomyocytes into 3D cardiac tissue. 2017 Biomaterials
Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss. 2017 Nat Commun
Bioreactor culture duration of engineered constructs influences bone formation by mesenchymal stem cells. 2017 Biomaterials
BMPs direct sensory interneuron identity in the developing spinal cord using signal-specific not morphogenic activities. 2017 Elife
Brief Report: External Beam Radiation Therapy for the Treatment of Human Pluripotent Stem Cell-Derived Teratomas. 2017 Stem Cells
Cardiac Fibroblasts Adopt Osteogenic Fates and Can Be Targeted to Attenuate Pathological Heart Calcification. 2017 Cell Stem Cell
Cell sex affects extracellular matrix protein expression and proliferation of smooth muscle progenitor cells derived from human pluripotent stem cells. 2017 Stem Cell Res Ther
Cell Type-Specific Chromatin Signatures Underline Regulatory DNA Elements in Human Induced Pluripotent Stem Cells and Somatic Cells. 2017 Circ Res
Cell-mediated enzyme prodrug cancer therapies. 2017 Adv Drug Deliv Rev
Cellular Phenotypes in Human iPSC-Derived Neurons from a Genetic Model of Autism Spectrum Disorder. 2017 Cell Rep
Characterization of the Corneal Subbasal Nerve Plexus in Limbal Stem Cell Deficiency. 2017 Cornea