Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
Imaging-Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i-Hep Applications. 2018 Stem Cell Reports
Impaired Notch Signaling Leads to a Decrease in p53 Activity and Mitotic Catastrophe in Aged Muscle Stem Cells. 2018 Cell Stem Cell
Improving Gene Editing Outcomes in Human Hematopoietic Stem and Progenitor Cells by Temporal Control of DNA Repair. 2018 Stem Cells
In Vitro and In Vivo Proteomic Comparison of Human Neural Progenitor Cell-Induced Photoreceptor Survival. 2018 Proteomics
In Vivo Evaluation of the Limbus Using Anterior Segment Optical Coherence Tomography. 2018 Transl Vis Sci Technol
Inducible Expression of GDNF in Transplanted iPSC-Derived Neural Progenitor Cells. 2018 Stem Cell Reports
Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M. 2018 Nat Commun
Inflammatory Cytokine TNFalpha Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. 2018 Cell
Integrated Stress Response Activity Marks Stem Cells in Normal Hematopoiesis and Leukemia. 2018 Cell Rep
Interspecies chimeras. 2018 Curr Opin Genet Dev
Intra-embryo Gene Cassette Knockin by CRISPR/Cas9-Mediated Genome Editing with Adeno-Associated Viral Vector. 2018 iScience
Inversion and computational maturation of drug response using human stem cell derived cardiomyocytes in microphysiological systems. 2018 Sci Rep
iPSC-Derived Organs In Vivo: Challenges and Promise. 2018 Cell Stem Cell
Isolation and functional assessment of mouse skeletal stem cell lineage. 2018 Nat Protoc
KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development. 2018 Nat Commun
Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment. 2018 Cell Stem Cell
Live-cell time-lapse imaging and single-cell tracking of in vitro cultured neural stem cells – Tools for analyzing dynamics of cell cycle, migration, and lineage selection. 2018 Methods
Loss of MECP2 Leads to Activation of P53 and Neuronal Senescence. 2018 Stem Cell Reports
LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. 2018 Nat Commun
Macrochimerism and clinical transplant tolerance. 2018 Hum Immunol
Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes. 2018 Nat Commun
Mechanoresponsive stem cells acquire neural crest fate in jaw regeneration. 2018 Nature
Metabolism in Pluripotent Stem Cells and Early Mammalian Development. 2018 Cell Metab
Mimicking Cartilage Tissue Zonal Organization by Engineering Tissue-Scale Gradient Hydrogels as 3D Cell Niche. 2018 Tissue Eng Part A
miRNA-based therapeutic potential of stem cell-derived extracellular vesicles: a safe cell-free treatment to ameliorate radiation-induced brain injury. 2018 Int J Radiat Biol
Modeling neurological diseases using iPSC-derived neural cells : iPSC modeling of neurological diseases. 2018 Cell Tissue Res
Modeling the Interplay Between Neurons and Astrocytes in Autism Using Human Induced Pluripotent Stem Cells. 2018 Biol Psychiatry
Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep. 2018 Transgenic Res
Multicellular Interactions in 3D Engineered Myocardial Tissue. 2018 Front Cardiovasc Med
Muscle stem cell activation in a mouse model of rotator cuff injury. 2018 J Orthop Res
Nanoparticle Delivery of TWIST Small Interfering RNA and Anticancer Drugs: A Therapeutic Approach for Combating Cancer. 2018 Enzymes
NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction. 2018 Nat Cell Biol
Nondestructive assessment of collagen hydrogel cross-linking using time-resolved autofluorescence imaging. 2018 J Biomed Opt
Nondestructive fluorescence lifetime imaging and time-resolved fluorescence spectroscopy detect cartilage matrix depletion and correlate with mechanical properties. 2018 Eur Cell Mater
Optimization of IL13Ralpha2-Targeted Chimeric Antigen Receptor T Cells for Improved Anti-tumor Efficacy against Glioblastoma. 2018 Mol Ther
Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche. 2018 Nature
Phase 1 clinical study of an embryonic stem cell-derived retinal pigment epithelium patch in age-related macular degeneration. 2018 Nat Biotechnol
Phase I Trial: Cirmtuzumab Inhibits ROR1 Signaling and Stemness Signatures in Patients with Chronic Lymphocytic Leukemia. 2018 Cell Stem Cell
PNPase knockout results in mtDNA loss and an altered metabolic gene expression program. 2018 PLoS One
Potent antitumor efficacy of anti-GD2 CAR T cells in H3-K27M(+) diffuse midline gliomas. 2018 Nat Med
Potential use of stem cells as a therapy for cystinosis. 2018 Pediatr Nephrol
Prevalence of glucocorticoid induced osteonecrosis in the mouse is not affected by treatments that maintain bone vascularity. 2018 Bone Rep
Production of Elastin-like Protein Hydrogels for Encapsulation and Immunostaining of Cells in 3D. 2018 J Vis Exp
Programmed cell removal by calreticulin in tissue homeostasis and cancer. 2018 Nat Commun
Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. 2018 Dev Cell
Promise of gene therapy to treat sickle cell disease. 2018 Expert Opin Biol Ther
Protein motion in the nucleus: from anomalous diffusion to weak interactions. 2018 Biochem Soc Trans
Protein-engineered hydrogels enhance the survival of induced pluripotent stem cell-derived endothelial cells for treatment of peripheral arterial disease. 2018 Biomater Sci
Recent evidence that TADs and chromatin loops are dynamic structures. 2018 Nucleus
Recent Progress in Developing Injectable Matrices for Enhancing Cell Delivery and Tissue Regeneration. 2018 Adv Healthc Mater