| Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-beta in iPSC-Derived Alzheimer’s Disease Neurons. |
2019 |
Cell Stem Cell |
| Chronic myelogenous leukemia stem cells require cell-autonomous pleiotrophin signaling. |
2019 |
J Clin Invest |
| Circulating tumor cells exhibit metastatic tropism and reveal brain metastasis drivers. |
2019 |
Cancer Discov |
| Classification of Limbal Stem Cell Deficiency Using Clinical and Confocal Grading. |
2019 |
Cornea |
| Combinatorial targeting of cancer bone metastasis using mRNA engineered stem cells. |
2019 |
EBioMedicine |
| Comparison of endothelial keratoplasty techniques in patients with prior glaucoma surgery – a case-matched study. |
2019 |
Am J Ophthalmol |
| Complex Oscillatory Waves Emerging from Cortical Organoids Model Early Human Brain Network Development. |
2019 |
Cell Stem Cell |
| CRISPR-mediated activation of a promoter or enhancer rescues obesity caused by haploinsufficiency. |
2019 |
Science |
| CTCF sites display cell cycle-dependent dynamics in factor binding and nucleosome positioning. |
2019 |
Genome Res |
| Determining cellular CTCF and cohesin abundances to constrain 3D genome models. |
2019 |
Elife |
| Determining the pharmacokinetics of nicotinic drugs in the endoplasmic reticulum using biosensors. |
2019 |
J Gen Physiol |
| Development of a Chimeric Model to Study and Manipulate Human Microglia In Vivo. |
2019 |
Neuron |
| Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer. |
2019 |
Cell Stem Cell |
| Development of innate immune cells from human pluripotent stem cells. |
2019 |
Exp Hematol |
| Diagnostic criteria for limbal stem cell deficiency before surgical intervention-A systematic literature review and analysis. |
2019 |
Surv Ophthalmol |
| Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity. |
2019 |
Cell Stem Cell |
| Distinct Classes of Chromatin Loops Revealed by Deletion of an RNA-Binding Region in CTCF. |
2019 |
Mol Cell |
| Editing the Sickle Cell Disease Mutation in Human Hematopoietic Stem Cells: Comparison of Endonucleases and Homologous Donor Templates. |
2019 |
Mol Ther |
| Effect of inoculum density on human-induced pluripotent stem cell expansion in 3D bioreactors. |
2019 |
Cell Prolif |
| Effects of Spaceflight and Simulated Microgravity on YAP1 Expression in Cardiovascular Progenitors: Implications for Cell-Based Repair. |
2019 |
Int J Mol Sci |
| Efficient Differentiation of Human Pluripotent Stem Cells into Liver Cells. |
2019 |
J Vis Exp |
| Enhanced Delivery of Oncolytic Adenovirus by Neural Stem Cells for Treatment of Metastatic Ovarian Cancer. |
2019 |
Mol Ther Oncolytics |
| Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. |
2019 |
Cell |
| Evaluating phase separation in live cells: diagnosis, caveats, and functional consequences. |
2019 |
Genes Dev |
| Evidence for DNA-mediated nuclear compartmentalization distinct from phase separation. |
2019 |
Elife |
| Fiber-based platform for synchronous imaging of endogenous and exogenous fluorescence of biological tissue. |
2019 |
Opt Lett |
| Fluorous-Soluble Metal Chelate for Sensitive Fluorine-19 Magnetic Resonance Imaging Nanoemulsion Probes. |
2019 |
ACS Nano |
| Generation of Antigen-Specific T Cells from Human Induced Pluripotent Stem Cells. |
2019 |
Methods Mol Biol |
| Generation of functional lungs via conditional blastocyst complementation using pluripotent stem cells. |
2019 |
Nat Med |
| Generation of pluripotent stem cell-derived mouse kidneys in Sall1-targeted anephric rats. |
2019 |
Nat Commun |
| Genomic Profiling of BDE-47 Effects on Human Placental Cytotrophoblasts. |
2019 |
Toxicol Sci |
| Glucose Metabolism Drives Histone Acetylation Landscape Transitions that Dictate Muscle Stem Cell Function. |
2019 |
Cell Rep |
| Harnessing the versatility of PLGA nanoparticles for targeted Cre-mediated recombination. |
2019 |
Nanomedicine |
| Hematopoietic stem cell-independent hematopoiesis and the origins of innate-like B lymphocytes. |
2019 |
Development |
| High-Efficiency, Selection-free Gene Repair in Airway Stem Cells from Cystic Fibrosis Patients Rescues CFTR Function in Differentiated Epithelia. |
2019 |
Cell Stem Cell |
| Highly Efficient and Marker-free Genome Editing of Human Pluripotent Stem Cells by CRISPR-Cas9 RNP and AAV6 Donor-Mediated Homologous Recombination. |
2019 |
Cell Stem Cell |
| Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility. |
2019 |
Nat Commun |
| Human induced pluripotent stem cell line with genetically encoded fluorescent voltage indicator generated via CRISPR for action potential assessment post-cardiogenesis. |
2019 |
Stem Cells |
| Human iPSC Generation from Antigen-Specific T Cells. |
2019 |
Methods Mol Biol |
| Human iPSCs can be differentiated into notochordal cells that reduce intervertebral disc degeneration in a porcine model. |
2019 |
Theranostics |
| Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients. |
2019 |
Nat Biotechnol |
| Hypoxic Preconditioning Enhances Survival and Proangiogenic Capacity of Human First Trimester Chorionic Villus-Derived Mesenchymal Stem Cells for Fetal Tissue Engineering. |
2019 |
Stem Cells Int |
| Identification of preexisting adaptive immunity to Cas9 proteins in humans. |
2019 |
Nat Med |
| Improved Computational Identification of Drug Response Using Optical Measurements of Human Stem Cell Derived Cardiomyocytes in Microphysiological Systems. |
2019 |
Front Pharmacol |
| In Utero Treatment of Myelomeningocele with Placental Mesenchymal Stromal Cells – Selection of an Optimal Cell Line in Preparation for Clinical Trials. |
2019 |
J Pediatr Surg |
| Inhibition of invasive pancreatic cancer: restoring cell apoptosis by activating mitochondrial p53. |
2019 |
Am J Cancer Res |
| Interaction between galectin-3 and cystinosin uncovers a pathogenic role of inflammation in kidney involvement of cystinosis. |
2019 |
Kidney Int |
| Lentiviral Gene Therapy Combined with Low-Dose Busulfan in Infants with SCID-X1. |
2019 |
N Engl J Med |
| Lentiviral Gene Therapy with Low Dose Busulfan for Infants with X-Linked Severe Combined Immune Deficiency (XSCID) results in the Development of a Normal and Sustained Immune System: Interim Results of an ongoing Phase I/II Clinical Study |
2019 |
ASGCT |
| LIM homeobox 2 promotes interaction between human iPS-derived hepatic progenitors and iPS-derived hepatic stellate-like cells. |
2019 |
Sci Rep |
