Publications by Grantees

The following list of publications describe research carried out with CIRM funding. Click on the publication title for a brief summary of the research and for more information about the CIRM grants that contributed to the research.

Title Year Journal
[Cystinosis: From the gene identification to the first gene therapy clinical trial]. 2023 Med Sci (Paris)
A bioactive material with dual integrin-targeting ligands regulates specific endogenous cell adhesion and promotes vascularized bone regeneration in adult and fetal bone defects. 2023 Bioact Mater
Abrupt perturbation and delayed recovery of the vaginal ecosystem following childbirth. 2023 Nat Commun
An Inexpensive 3D Printed Mouse Model of Successful, Complication-free Long Bone Distraction Osteogenesis. 2023 Plast Reconstr Surg Glob Open
Antiretrovirals to CCR5 CRISPR/Cas9 gene editing – A paradigm shift chasing an HIV cure. 2023 Clin Immunol
Assaying Chemical Long-Term Potentiation in Human iPSC-Derived Neuronal Networks. 2023 Methods Mol Biol
Automated 384-well SYBR Green Expression Array for Optimization of Human Induced Pluripotent Stem Cell Differentiation. 2023 Bio Protoc
CD203c is expressed by human fetal hepatoblasts and distinguishes subsets of hepatoblastoma. 2023 Front Oncol
Cellular Therapy for Children with Central Nervous System Tumors: Mining and Mapping the Correlative Data. 2023 Curr Oncol Rep
Combination of Distinct Vascular Stem/Progenitor Cells for Neovascularization and Ischemic Rescue. 2023 Arterioscler Thromb Vasc Biol
Developing Hypoimmunogenic Human iPSC-Derived Oligodendrocyte Progenitor Cells as an Off-The-Shelf Cell Therapy for Myelin Disorders. 2023 Adv Sci (Weinh)
Engineered multi-functional, pro-angiogenic collagen-based scaffolds loaded with endothelial cells promote large deep burn wound healing. 2023 Front Pharmacol
Establishing a Disease-in-a-Dish Model to Study SARS-CoV-2 Infection During Prenatal Development. 2023 Curr Protoc
FGF18 promotes human lung branching morphogenesis through regulating mesenchymal progenitor cells. 2023 Am J Physiol Lung Cell Mol Physiol
Graphene-based cardiac sensors and actuators. 2023 Front Bioeng Biotechnol
Hardwiring tissue-specific AAV transduction in mice through engineered receptor expression. 2023 Nat Methods
Human iPSC-derived neural progenitor cells secreting GDNF provide protection in rodent models of ALS and retinal degeneration. 2023 Stem Cell Reports
Identification of SALL4 Expressing Islet-1+ Cardiovascular Progenitor Cell Clones. 2023 Int J Mol Sci
In utero delivery of mRNA to the heart, diaphragm and muscle with lipid nanoparticles. 2023 Bioact Mater
Inclusion of 4-1BB Costimulation Enhances Selectivity and Functionality of IL13Ralpha2-Targeted Chimeric Antigen Receptor T Cells. 2023 Cancer Res Commun
Inhibition of HSD17B13 protects against liver fibrosis by inhibition of pyrimidine catabolism in nonalcoholic steatohepatitis. 2023 Proc Natl Acad Sci U S A
MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model. 2023 iScience
Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition. 2023 bioRxiv
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance. 2023 Sci Adv
Stem Cell-Based Organoid Models of Neurodevelopmental Disorders. 2023 Biol Psychiatry
T-allo10 Infusion after αβ depleted-HSCT in Children and Young Adults with Hematologic Malignancies: Improved Immune Reconstitution in the Absence of Severe GvHD 2023 Transplantation and Cellular Therapy
Therapeutic blood-brain barrier modulation and stroke treatment by a bioengineered FZD(4)-selective WNT surrogate in mice. 2023 Nat Commun
Transcriptomic Effects on the Mouse Heart Following 30 Days on the International Space Station. 2023 Biomolecules
TRF2 rescues telomere attrition and prolongs cell survival in Duchenne muscular dystrophy cardiomyocytes derived from human iPSCs. 2023 Proc Natl Acad Sci U S A
Tumor inflammation-associated neurotoxicity. 2023 Nat Med
A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs. 2022 Nat Commun
A randomized placebo-controlled phase 3 study of mesenchymal stem cells induced to secrete high levels of neurotrophic factors in amyotrophic lateral sclerosis. 2022 Muscle Nerve
A reference human induced pluripotent stem cell line for large-scale collaborative studies. 2022 Cell Stem Cell
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery. 2022 Cell Stem Cell
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice. 2022 Cell Rep
Adapting Physiology in Functional Human Islet Organogenesis. 2022 Front Cell Dev Biol
Advancing preclinical models of psychiatric disorders with human brain organoid cultures. 2022 Mol Psychiatry
Altered adult neurogenesis and gliogenesis in patients with mesial temporal lobe epilepsy. 2022 Nat Neurosci
An Ex Vivo 3D Tumor Microenvironment-Mimicry Culture to Study TAM Modulation of Cancer Immunotherapy. 2022 Cells
Anti-GD2 synergizes with CD47 blockade to mediate tumor eradication. 2022 Nat Med
Antibody screening data of human midgestation liver cells with a focus on hematopoietic, liver sinusoidal endothelial, and hepatoblast cell-populations. 2022 BMC Res Notes
Biomarkers of in vivo limbal stem cell function. 2022 Ocul Surf
Brain organoids, consciousness, ethics and moral status. 2022 Semin Cell Dev Biol
c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity. 2022 iScience
Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation. 2022 Cell
CDK12 is hyperactivated and a synthetic-lethal target in BRAF-mutated melanoma. 2022 Nat Commun
Cell Morphology as an In Vivo Parameter for the Diagnosis of Limbal Stem Cell Deficiency. 2022 Cornea
Collateral Arteriogenesis Involves a Sympathetic Denervation That Is Associated With Abnormal alpha-Adrenergic Signaling and a Transient Loss of Vascular Tone. 2022 Front Cardiovasc Med
Comment on: Long-Term Outcome After Superficial Keratectomy of the Abnormal Epithelium for Partial Limbal Stem Cell Deficiency. 2022 Am J Ophthalmol
COVID-19 vaccination elicits an evolving, cross-reactive antibody response to epitopes conserved with endemic coronavirus spike proteins. 2022 Cell Rep
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